For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0506 (mmpS2)

annotation: PROBABLE CONSERVED MEMBRANE PROTEIN MMPS2
coordinates: 596759 - 597202
length: 147

VRMISVSGAVKRMWLLLAIVVVAVVGGLGIYRLHSIFGVHEQPTVMVKPDFDVPLFNPKRVTYEVFGPAK
TAKIAYLDPDARVHRLDSVSLPWSVTVETTLPAVSVNLMAQSNADVISCRIIVNGAVKDERSETSPRALT
SCQVSSG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0506mmpS2-100% (147)PROBABLE CONSERVED MEMBRANE PROTEIN MMPS2
M. tuberculosis H37RvRv0677cmmpS51e-2642.25% (142) hypothetical protein Rv0677c
M. tuberculosis H37RvRv0403cmmpS15e-2642.14% (140) membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0518mmpS24e-80100.00% (147) membrane protein
M. gilvum PYR-GCKMflv_3028-4e-2543.80% (137) membrane family protein
M. leprae Br4923MLBr_02377-5e-2945.14% (144) hypothetical protein MLBr_02377
M. abscessus ATCC 19977MAB_3149-4e-2539.13% (138) MmpS family protein
M. marinum MMMAR_0839-3e-5468.75% (144) MmpS-family membrane protein
M. avium 104MAV_3247-4e-2943.48% (138) MmpS4 protein
M. smegmatis MC2 155MSMEG_3495-6e-2841.10% (146) MmpS5 protein
M. thermoresistible (build 8)TH_2866-6e-2739.71% (136) PUTATIVE hypothetical protein Mvan_3834
M. ulcerans Agy99MUL_3687mmpS5_17e-2844.20% (138) membrane protein MmpS5_1
M. vanbaalenii PYR-1Mvan_1058-3e-2743.80% (137) hypothetical protein Mvan_1058

CLUSTAL 2.0.9 multiple sequence alignment


TH_2866|M.thermoresistible__bu      -----LWTSKAKDSAILTRLARAWIPLVMVVVVAIGGFAVWRIRGIFGSE
MUL_3687|M.ulcerans_Agy99           ------------------MLKRAWIPLLMVVVLAISGFVVSRLHKIFGSE
MLBr_02377|M.leprae_Br4923          ----MSKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASE
MAV_3247|M.avium_104                -------------------MKRLWIPLVIVAVVVAGGLTVSRLHGIFGSE
MAB_3149|M.abscessus_ATCC_1997      ---------------MFRTIRKIWMPLLIAAVVAIGGFAVFRVRGIFGSE
Mflv_3028|M.gilvum_PYR-GCK          ---------------MITVVKRVWLPVLIVVALAIGFVSISYLRSVFGS-
Mvan_1058|M.vanbaalenii_PYR-1       ---------------MITVVKRVWLPVLVIAAVAVGAVTVANLRSVFGS-
MSMEG_3495|M.smegmatis_MC2_155      MMAVDTKDKQRKKFSISALARRFWIPLLIGAVVFVGAFTVMRVRTFFGSG
Rv0506|M.tuberculosis_H37Rv         ----------MRMISVSGAVKRMWLLLAIVVVAVVGGLGIYRLHSIFGVH
Mb0518|M.bovis_AF2122/97            ----------MRMISVSGAVKRMWLLLAIVVVAVVGGLGIYRLHSIFGVH
MMAR_0839|M.marinum_M               ------------MIPVTSVVRRMWLLLAVMGVALVAGLGIYRLHRVFGVH
                                                         : *: : :  .   . . :  ::  *.  

TH_2866|M.thermoresistible__bu      QLPTYAGSTSVDTDKANPKRVRYEIFGAPGTVADINYIDAEGDPHQVNGA
MUL_3687|M.ulcerans_Agy99           DLNANAG-AGIDIVQFNPKVVIYEISGPAGSTANINFWDADANTHQVNAA
MLBr_02377|M.leprae_Br4923          KRESYADSNLGSSKPFNPKQIVYEVFGPPGTVADISYFDANSDPQRIDGA
MAV_3247|M.avium_104                KRPSYADTRQQDTKPFNPKHVKYEVFGPAGAMADISYFDANGEPQHINGV
MAB_3149|M.abscessus_ATCC_1997      SFGASADNNAKDAVPYNPKTLVYEIFGEPGAMADVNYFNEDAQPTRVDNV
Mflv_3028|M.gilvum_PYR-GCK          NGAVVTPVGSDTAEDFNPTVVTYEVFG-TGSFAVINYTDLDGLPQRTGQV
Mvan_1058|M.vanbaalenii_PYR-1       DKAIVTPVDADTAENFNPKVVTYEIFG-SGSTATINYADLDGKPQRTGEV
MSMEG_3495|M.smegmatis_MC2_155      DDPSLASAKVDDTKPFDPKVVVYEIYGEPGATADINYLDLDAQPQRVDGA
Rv0506|M.tuberculosis_H37Rv         EQPTVMVKPDFDVPLFNPKRVTYEVFG-PAKTAKIAYLDPDARVHRLDSV
Mb0518|M.bovis_AF2122/97            EQPTVMVKPDFDVPLFNPKRVTYEVFG-PAKTAKIAYLDPDARVHRLDSV
MMAR_0839|M.marinum_M               EQPVVQAAADTDVPQFNPKYVTYEVYG-PAPSARIAYLDPDAHVRQLSDV
                                    .               :*. : **: * ..  * : : : :.   : . .

TH_2866|M.thermoresistible__bu      TLPWSIEIVTNSPAMAGNVLAQGDSDFIGCRIVSDGVVKDERTTQRVSAY
MUL_3687|M.ulcerans_Agy99           PLPWSFTISTTLPSVSANIMAQGDGSQIGCRITVDGVVREEKSAAGVNPQ
MLBr_02377|M.leprae_Br4923          QLPWSLLMTTTLAAVMGNLVAQGNTDSIGCRIIVDGVVKAERVSNEVNAY
MAV_3247|M.avium_104                ELPWTFDISTTLPSIVGNVVAQGNSDSLGCRILVDGVVKTERISHELNAF
MAB_3149|M.abscessus_ATCC_1997      QLPWAFKIVSTLPSLSGNIVAQGNGDQIGCRITVNGEVKMERVSTEHNAY
Mflv_3028|M.gilvum_PYR-GCK          SLPWTLTLETTIPSVRPDLLAQGNGQFIGCRVTVDGEVEDERTAEGVNAA
Mvan_1058|M.vanbaalenii_PYR-1       SLPWSLTLETTLPSVMPNIMAQGDGQSITCRVTVDDEVKDERTAEGLNAA
MSMEG_3495|M.smegmatis_MC2_155      TLPWSLTLSTTAPSVFPNIVAQGNGDTITCRITVDDELKDERTSNGVNAQ
Rv0506|M.tuberculosis_H37Rv         SLPWSVTVETTLPAVSVNLMAQSNADVISCRIIVNGAVKDERSETSPRAL
Mb0518|M.bovis_AF2122/97            SLPWSVTVETTLPAVSVNLMAQSNADVISCRIIVNGAVKDERSETSPRAL
MMAR_0839|M.marinum_M               PLPWSQTVSTSLPAVSVNLLAQSNAEELSCRILVNGAVKDQRSVSRPKAL
                                     ***:  : :. .::  :::**.: . : **:  :. :. ::      . 

TH_2866|M.thermoresistible__bu      VYCFTKSA
MUL_3687|M.ulcerans_Agy99           TFCLVKSA
MLBr_02377|M.leprae_Br4923          TYCLVKSA
MAV_3247|M.avium_104                TYCVLTAT
MAB_3149|M.abscessus_ATCC_1997      IYCLVKSA
Mflv_3028|M.gilvum_PYR-GCK          TYCLVKAA
Mvan_1058|M.vanbaalenii_PYR-1       TYCLVKAA
MSMEG_3495|M.smegmatis_MC2_155      TFCLVKSA
Rv0506|M.tuberculosis_H37Rv         TSCQVSSG
Mb0518|M.bovis_AF2122/97            TSCQVSSG
MMAR_0839|M.marinum_M               TFCQVTSA
                                      *  .: