For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4648 (-)

annotation: DNA-binding protein
coordinates: 4735102 - 4736106
length: 334

AHRYKVREIAQQCGLSEATVDRVLNNRPGVRENTRAEVRQAIADLDKQRAQLRLNGRRFLIDVVMQTPRR
FSDAFRTAVEAELPAFAPALLRARFHLWESGSTAQMVDTLARIKSSHGVVLKAADEPEVVEAVDRLVAAG
VPVVTYTTDVPTSARCAYVGIDNHGAGATAAYLIEQWLGADPADVLITLSRTVFRGEGEREVGFRSGLRA
SGRTVVEVTDSDGIDATNERLVLQALERNPSVGAVYSPGGGNTATVAAFDRLGRHCKVFIAHDLDVDNRR
LLRDGRISAVLHNDLRADARLAMRLILQQHGALPAEPVRPAPIQVVTPYNLPM*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4648--100% (334)DNA-binding protein
M. smegmatis MC2 155MSMEG_6376-8e-0824.60% (248) transcriptional regulator LacI family protein
M. smegmatis MC2 155MSMEG_1708-9e-0529.28% (181) ribose operon repressor, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2615-1e-15680.84% (334) regulatory protein, LacI
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3966-1e-16285.33% (334) regulatory protein, LacI

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2615|M.gilvum_PYR-GCK          MAHRYKVREIAQQSGLSEATVDRVLNNRPGVRENTVAEVRQAIADLDKQR
Mvan_3966|M.vanbaalenii_PYR-1       MAHRYKVREIAQQSGLSEATVDRVLHNRPGVRENTVAEVNQAIADLDKQR
MSMEG_4648|M.smegmatis_MC2_155      MAHRYKVREIAQQCGLSEATVDRVLNNRPGVRENTRAEVRQAIADLDKQR
                                    *************.***********:********* ***.**********

Mflv_2615|M.gilvum_PYR-GCK          SQLRLNGRRYLIDVVMQTPQRFSDAFRAAVEAELPAFAPAMVRARFHLWE
Mvan_3966|M.vanbaalenii_PYR-1       AQLRLNGRRYLIDVVMQTPRRFSDAFRAAVEAELPAFAPAMLRARFHLWE
MSMEG_4648|M.smegmatis_MC2_155      AQLRLNGRRFLIDVVMQTPRRFSDAFRTAVEAELPAFAPALLRARFHLWE
                                    :********:*********:*******:************::********

Mflv_2615|M.gilvum_PYR-GCK          SGETAQMVEALGRLRGSHGVVLKAQDEPEVAEAIDRLVGSGVPVVTYTTD
Mvan_3966|M.vanbaalenii_PYR-1       SGSTAQMVEALGRIRGSHGVVLKAQDDPAVAEAVDRLVDSGVPVVTYTTD
MSMEG_4648|M.smegmatis_MC2_155      SGSTAQMVDTLARIKSSHGVVLKAADEPEVVEAVDRLVAAGVPVVTYTTD
                                    **.*****::*.*::.******** *:* *.**:**** :**********

Mflv_2615|M.gilvum_PYR-GCK          VPGSSRCGYVGIDNHGAGMTAAYLVQQWLGEATSGVLITLSRTAFRGEGE
Mvan_3966|M.vanbaalenii_PYR-1       VPSSARCGYVGIDNHGAGVTAAYLVQQWLGEAPADVLITLSRTVFRGEGE
MSMEG_4648|M.smegmatis_MC2_155      VPTSARCAYVGIDNHGAGATAAYLIEQWLGADPADVLITLSRTVFRGEGE
                                    ** *:**.********** *****::****  .:.********.******

Mflv_2615|M.gilvum_PYR-GCK          REVGFRSALRGSGRPVIEVSDSDGIDATNEALVLAALEANPTVEAVYSVG
Mvan_3966|M.vanbaalenii_PYR-1       REVGFRSALRNCGRTIVEVSDSDGIDATNERLVLDALAANPGVQAVYSVG
MSMEG_4648|M.smegmatis_MC2_155      REVGFRSGLRASGRTVVEVTDSDGIDATNERLVLQALERNPSVGAVYSPG
                                    *******.** .**.::**:********** *** **  ** * **** *

Mflv_2615|M.gilvum_PYR-GCK          GGNVATVSAFERLNRVCRVFVAHDLDADNRRLLREGRISAVLHNDLRADA
Mvan_3966|M.vanbaalenii_PYR-1       GGNVATVAAFEKIGRDCKVFIAHDLDADNRRLLRDGRISAVLHNDLRADA
MSMEG_4648|M.smegmatis_MC2_155      GGNTATVAAFDRLGRHCKVFIAHDLDVDNRRLLRDGRISAVLHNDLRADA
                                    ***.***:**:::.* *:**:*****.*******:***************

Mflv_2615|M.gilvum_PYR-GCK          RLAVRSILQERGALPVESTKPVPIQIVTPYNMPLHF
Mvan_3966|M.vanbaalenii_PYR-1       RLALRLILQERGALPVEPVRPVPIQVVTPYNLPVHP
MSMEG_4648|M.smegmatis_MC2_155      RLAMRLILQQHGALPAEPVRPAPIQVVTPYNLPM--
                                    ***:* ***::****.*..:*.***:*****:*: