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SVPARPAPLFADIDDVARKLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVGKTELARAVAQCTGSEL VRLQCYEGVDEARALYEWNHAKQILRIQAGNAAAAGDSDAWEQTKTDVFSEEFLLTRPLLTAIKRTDPTV LLIDETDKADIEIEGLLLEVLSDFAVTVPELGTITAERPPFVVLTSNATRELSEALKRRCLFLHIDFPDP DLERRILLSRVPELPEHIASELVRIIGVLRGMQLKKLPSVAETIDWGRTVLALGMDTIDDEMIAATLGVI LKHQSDQQRAAGELKLN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4583 | - | - | 100% (298) | ATPase associated with various cellular activities |
| M. smegmatis MC2 155 | MSMEG_6241 | - | 3e-64 | 43.93% (305) | ATPase associated with various cellular activities, AAA-5 |
| M. smegmatis MC2 155 | MSMEG_0748 | - | 4e-60 | 43.37% (279) | ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2450c | - | 1e-144 | 86.91% (298) | hypothetical protein Mb2450c |
| M. gilvum PYR-GCK | Mflv_2645 | - | 1e-145 | 88.93% (298) | ATPase |
| M. tuberculosis H37Rv | Rv2426c | - | 1e-145 | 87.25% (298) | hypothetical protein Rv2426c |
| M. leprae Br4923 | MLBr_02490 | clpB | 2e-05 | 27.08% (144) | heat shock protein |
| M. abscessus ATCC 19977 | MAB_1619 | - | 1e-135 | 84.19% (291) | hypothetical protein MAB_1619 |
| M. marinum M | MMAR_3752 | - | 1e-144 | 86.91% (298) | hypothetical protein MMAR_3752 |
| M. avium 104 | MAV_1748 | - | 1e-148 | 88.93% (298) | ATPase associated with various cellular activities |
| M. thermoresistible (build 8) | TH_0791 | - | 1e-152 | 91.95% (298) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3695 | - | 1e-144 | 86.91% (298) | hypothetical protein MUL_3695 |
| M. vanbaalenii PYR-1 | Mvan_3933 | - | 1e-146 | 87.92% (298) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 MDSFNPTTKMQVALTSALQAASSAGNPEIRPVHLLLAMLMQNDGIAAPLL
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 ETVGVEPDIVRNEAQRLLERLPQASGCSSQPQLSRESLAAITTAQQLATE
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 MDDEYVSTEHLMLGLAMGDSDVAKLLTGHGASPQVLREAFVKIRGSARVT
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 SSDPEFTYQALEKYSTDLTAQSGEGKLDPVIGRDNEIRRVVQVLSRRTKN
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 NPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTLVALDLGSMVAGAK
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 YRGEFEQRLKVVLDDIKFSAGQIITFIDELHTIVGAGATGESAMDAGNMI
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 KPMLARGELRLVGATTLDEYRRYIEKDAALERRFQQIFVGEPSVEDTVGI
MSMEG_4583|M.smegmatis_MC2_155 --------------------------------------------------
TH_0791|M.thermoresistible__bu --------------------------------------------------
Mflv_2645|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3933|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2450c|M.bovis_AF2122/97 --------------------------------------------------
Rv2426c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3752|M.marinum_M --------------------------------------------------
MUL_3695|M.ulcerans_Agy99 --------------------------------------------------
MAV_1748|M.avium_104 --------------------------------------------------
MAB_1619|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02490|M.leprae_Br4923 LRGLKDRYEVHHGVRITDSALVAAAALSDRYITARFLPDKAIDLVDEAAS
MSMEG_4583|M.smegmatis_MC2_155 ---MSVPARP--------------------------------APLFADID
TH_0791|M.thermoresistible__bu ---VSLPARS--------------------------------APLFADID
Mflv_2645|M.gilvum_PYR-GCK ---MSVPASI--------------------------------QPLFADID
Mvan_3933|M.vanbaalenii_PYR-1 ---MSVPAQT--------------------------------VPLFADID
Mb2450c|M.bovis_AF2122/97 ---MTVPARP--------------------------------TPLFADIA
Rv2426c|M.tuberculosis_H37Rv ---MTVPARP--------------------------------TPLFADIA
MMAR_3752|M.marinum_M ---MSVPARS--------------------------------VPLFADIA
MUL_3695|M.ulcerans_Agy99 ---MSVPARS--------------------------------VPLFADIA
MAV_1748|M.avium_104 ---MSVPARP--------------------------------RPLFADID
MAB_1619|M.abscessus_ATCC_1997 ---MSDPLRPSGSSQSR----------------------TQTAPLFTSID
MLBr_02490|M.leprae_Br4923 RLRMEIDSRPVEIDEVERLVRRFEIEEMALVNEEDEASKERLETLRAELA
: .* :.:
MSMEG_4583|M.smegmatis_MC2_155 DVARKLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
TH_0791|M.thermoresistible__bu DVSRRLAETGYLPDTATATAVYLADRLGKPLLVEGPAGVG----------
Mflv_2645|M.gilvum_PYR-GCK DVARRLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
Mvan_3933|M.vanbaalenii_PYR-1 DVARRLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
Mb2450c|M.bovis_AF2122/97 DVSRRLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
Rv2426c|M.tuberculosis_H37Rv DVSRRLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
MMAR_3752|M.marinum_M DVSRRLAQTGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
MUL_3695|M.ulcerans_Agy99 DVSRRLAQTGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
MAV_1748|M.avium_104 DVSRRLAETGYLPDTATATAVFLADRLGKPLLVEGPAGVG----------
MAB_1619|M.abscessus_ATCC_1997 DVTTRLAETGYLADTATATAVFLADRLGKPLLVEGPAGVG----------
MLBr_02490|M.leprae_Br4923 DQKERLAELTARWQNEKNAIDVVRELKEQLETLRGESERAERDGDLAKAA
* :**: :. . : : : : :.* : .
MSMEG_4583|M.smegmatis_MC2_155 ----------KTELARAVAQCTGSELVRLQCYEGVDEAR-ALYEWN----
TH_0791|M.thermoresistible__bu ----------KTELARAVAQATGSELVRLQCYEGVDEAR-ALYEWN----
Mflv_2645|M.gilvum_PYR-GCK ----------KTELARAIAQSTGSGLVRLQCYEGVDESR-ALYEWN----
Mvan_3933|M.vanbaalenii_PYR-1 ----------KTELARAIAQSTGSELVRLQCYEGVDESR-ALYEWN----
Mb2450c|M.bovis_AF2122/97 ----------KTELARAVAQATGSGLVRLQCYEGVDEAR-ALYEWN----
Rv2426c|M.tuberculosis_H37Rv ----------KTELARAVAQATGSGLVRLQCYEGVDEAR-ALYEWN----
MMAR_3752|M.marinum_M ----------KTELARAVAQATGSGLVRLQCYEGVDEAR-ALYEWN----
MUL_3695|M.ulcerans_Agy99 ----------KTELARAVAQATGSGLVRLQCYEGVDEAR-ALYEWN----
MAV_1748|M.avium_104 ----------KTELARAVAQATGSGLVRLQCYEGVDEAR-ALYEWN----
MAB_1619|M.abscessus_ATCC_1997 ----------KTELARAVAHTTGSGLVRLQCYEGVDEAR-ALYEWN----
MLBr_02490|M.leprae_Br4923 ELRYGRIPEVEKKLEAAVPTAQAREDVMLKEEVGPDDIANVVSAWTGIPA
:.:* *:. . * *: * *: .: *.
MSMEG_4583|M.smegmatis_MC2_155 ------HAKQILRIQAGN-------------------AAAAGDSDAWEQT
TH_0791|M.thermoresistible__bu ------HAKQILRIQAGN-------------------AGAGG--EAWERT
Mflv_2645|M.gilvum_PYR-GCK ------HAKQILRIQAG-----------------------HG---DWDQT
Mvan_3933|M.vanbaalenii_PYR-1 ------HAKQILRIQAG-----------------------QGEGADWDRT
Mb2450c|M.bovis_AF2122/97 ------HAKQILRIQAG-----------------------SG---DWEAT
Rv2426c|M.tuberculosis_H37Rv ------HAKQILRIQAG-----------------------SG---DWEAT
MMAR_3752|M.marinum_M ------HAKQILRIQSG-----------------------SG---DWEAT
MUL_3695|M.ulcerans_Agy99 ------HAKQILRIQSG-----------------------SG---DWEAT
MAV_1748|M.avium_104 ------HAKQILRIQAG-----------------------SG---DWDQT
MAB_1619|M.abscessus_ATCC_1997 ------HAKQILRIQAG-----------------------SG---DWDET
MLBr_02490|M.leprae_Br4923 GRLLEGETAKLLRMEDELGKRVVGQKKAVHAVSDAVRRSRAGVADPNRPT
.: ::**:: * *
MSMEG_4583|M.smegmatis_MC2_155 KTDVFS--------------EEFLLTR-----------------------
TH_0791|M.thermoresistible__bu KDDVFS--------------EEFLLSR-----------------------
Mflv_2645|M.gilvum_PYR-GCK RDDVFS--------------EEFLLTR-----------------------
Mvan_3933|M.vanbaalenii_PYR-1 KDDVFS--------------EEFLLTR-----------------------
Mb2450c|M.bovis_AF2122/97 KTDVLS--------------EEFLLQR-----------------------
Rv2426c|M.tuberculosis_H37Rv KTDVFS--------------EEFLLQR-----------------------
MMAR_3752|M.marinum_M KDDVFS--------------EEFLLQR-----------------------
MUL_3695|M.ulcerans_Agy99 KDDVFS--------------EEFLLQR-----------------------
MAV_1748|M.avium_104 KTDVFS--------------EEFLLQR-----------------------
MAB_1619|M.abscessus_ATCC_1997 KTDVFA--------------EEFLLSR-----------------------
MLBr_02490|M.leprae_Br4923 GSFLFLGPTGVGKTELAKALADFLFDDQRAMVRVDMSEYGEKHSVARLVG
:: :**:
MSMEG_4583|M.smegmatis_MC2_155 ------------PLLTAIKRTDPTVLLIDETDKADIEIEGLLLEVLS---
TH_0791|M.thermoresistible__bu ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
Mflv_2645|M.gilvum_PYR-GCK ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
Mvan_3933|M.vanbaalenii_PYR-1 ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
Mb2450c|M.bovis_AF2122/97 ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
Rv2426c|M.tuberculosis_H37Rv ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
MMAR_3752|M.marinum_M ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
MUL_3695|M.ulcerans_Agy99 ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
MAV_1748|M.avium_104 ------------PLLTAIRRTEPTVLLIDETDKADIEIEGLLLEVLS---
MAB_1619|M.abscessus_ATCC_1997 ------------PLLTAIRREDPTVLLIDETDKADIEIEGLLLEVLS---
MLBr_02490|M.leprae_Br4923 APPGYIGHDQGGQLTEAVRRRPYTVVLFDEVEKAHSDVFDVLLQVLDEGR
* *::* **:*:**.:**. :: .:**:**.
MSMEG_4583|M.smegmatis_MC2_155 ---------DFAVTVPELG-TITAERPPFVVLTSNATRELSEALKRRCLF
TH_0791|M.thermoresistible__bu ---------DFAVTVPELG-TITAERIPFVVLTSNATRELSEALKRRCLF
Mflv_2645|M.gilvum_PYR-GCK ---------DFAVTVPELG-TITAERRPLVVLTSNATRELSEALKRRCLF
Mvan_3933|M.vanbaalenii_PYR-1 ---------DFAVTVPELG-TITAERRPLVVLTSNATRELSEALKRRCLF
Mb2450c|M.bovis_AF2122/97 ---------DFAVTVPELG-TLTATRAPFVLLTSNATRELSEALKRRCLY
Rv2426c|M.tuberculosis_H37Rv ---------DFAVTVPELG-TLTATRAPFVLLTSNATRELSEALKRRCLY
MMAR_3752|M.marinum_M ---------DFAVTVPELG-TLTAARAPFVLLTSNATRELSEALKRRCLF
MUL_3695|M.ulcerans_Agy99 ---------DFAVTVPELG-TLTATRAPFVLLTSNATRELSEALKRRCLF
MAV_1748|M.avium_104 ---------DFAVTVPELG-TLTAERPPFVVLTSNATRELSEALKRRCLF
MAB_1619|M.abscessus_ATCC_1997 ---------DFAVTIPELG-TIAASRKPFVLLTSNATRELSEALKRRCLF
MLBr_02490|M.leprae_Br4923 LTDGQGRTVDFRNTIPILTSNLGSGGSEEQVMAAVRSVFKPEFINRLDDV
** *:* * .: : :::: : .* ::*
MSMEG_4583|M.smegmatis_MC2_155 LHIDFPDPDLERRILLSRVPELPEHIASELVRIIGVLRGMQLKKLPSVAE
TH_0791|M.thermoresistible__bu LHIDFPDPDLERRILLSRVPELPERIASELVRIVGVLRGMQLKKLPSVAE
Mflv_2645|M.gilvum_PYR-GCK LHIDFPDPDLERRILLSRVPELPERLAEELVRIIGVLRGMQLKKLPSVAE
Mvan_3933|M.vanbaalenii_PYR-1 LHIDFPDPDLERRILLSRVPELPERLAEELVRIIGVLRGMALKKLPSVAE
Mb2450c|M.bovis_AF2122/97 LHIDFPTPELERRILLSRVPELPEHFAEELVRIIGVLRGMQLKKVPSIAE
Rv2426c|M.tuberculosis_H37Rv LHIDFPTPELERRILLSRVPELPEHFAEELVRIIGVLRGMQLKKVPSIAE
MMAR_3752|M.marinum_M LHIDFPTPEMERRILLSRVPELPEHIAEELVRIIGVLRGMQLKKLPSIAE
MUL_3695|M.ulcerans_Agy99 LHIDFPTPEMERRILLSRVPELPEHIAEELVRIIGVLRGMQLKKLPSIAE
MAV_1748|M.avium_104 LHIDFPSPDLERRILLSRVPELPAHLADELVRIIGVLRGMQLKKVPSIAE
MAB_1619|M.abscessus_ATCC_1997 LHIDFPDAELERRILLKRVPELPASLAEELVRIIGVLRNMQLKKVPSVAE
MLBr_02490|M.leprae_Br4923 LIFDGLNPEELVRIVDIQLEQLGKRLAQRRLQLEVSLPAKRWLAQHGFDP
* :* .: **: :: :* :*.. ::: * ..
MSMEG_4583|M.smegmatis_MC2_155 TIDWGRTVLALGMDTIDDEMIAATLGVILKHQSDQ---QRAAGELKLN-
TH_0791|M.thermoresistible__bu TIDWARTVLALGMDTIDDEMIAATLGVVLKHQSDQ---QRAISELKLN-
Mflv_2645|M.gilvum_PYR-GCK TIDWARTVLALGMDTIDDEVIAATLGVVLKHQSDQ---IKAAGELRLN-
Mvan_3933|M.vanbaalenii_PYR-1 TIDWGRTLLALGMDTVDDEVIAATLGVVLKHQSDQ---IKASGELRLN-
Mb2450c|M.bovis_AF2122/97 TIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQ---QRATGELRLN-
Rv2426c|M.tuberculosis_H37Rv TIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQ---QRATGELRLN-
MMAR_3752|M.marinum_M TIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQ---QRATGELRLN-
MUL_3695|M.ulcerans_Agy99 TIDWGRTVLALGLDTIDDAVVAATLGVVLKHQSDQ---QRATGELRLN-
MAV_1748|M.avium_104 TIDWGRTLLALGLDTIDDAVVAATLGVVLKHQSDQ---QRATGELRLN-
MAB_1619|M.abscessus_ATCC_1997 TIDWGRTILALGLDTLDDAVIASTLGVVLKHHSDQ---QRAAGELRLN-
MLBr_02490|M.leprae_Br4923 -VYGARPLRRLVQQAIGDQLAKMLLAGEVHDGDTLPVNVRPDGEALILG
: .*.: * :::.* : *. ::. . :. .* :