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RAITALLTLLPLAICALSGCSARGTEPSPHEETTNYPLTFENCGVTVTIDRPPQRVVSLYQASTEILLSL GLADRMVGTSTWFDPVLPALAEDNASVPRLADNDPSLETVLAAEPDLVTSASAHTFTPAVVAERARLGQL GVATYQSPSVCTGAEVDGETVTRTEPLTFDTLFDEINQLARMFDVPERGARLVDDLQRRLSEASLEPKPG TTVAYWFSGLRTPSMAGCCSAPGLYTAALGLANVFADASEDWPEVSWEAVAARDPDVLVLADLNRRRIDG DALDAKIGFLESNPVTRHMTAVRNKRYVVLTGSELDPGIRQVQAVEKMAAGLESFGLVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4561 | - | - | 100% (340) | ABC Fe3+-siderophores transporter, periplasmic binding protein |
| M. smegmatis MC2 155 | MSMEG_4560 | - | 2e-93 | 53.07% (326) | periplasmic binding protein |
| M. smegmatis MC2 155 | MSMEG_6064 | - | 2e-41 | 32.63% (334) | lipoprotein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3882 | - | 1e-42 | 32.92% (319) | periplasmic binding protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0547c | - | 8e-24 | 27.62% (315) | putative iron compound ABC transporter, substrate-binding |
| M. marinum M | MMAR_3037 | cobN | 8e-06 | 28.00% (275) | cobalamin biosynthesis protein, CobN |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3189 | - | 2e-87 | 49.70% (332) | PUTATIVE periplasmic binding protein |
| M. ulcerans Agy99 | MUL_2277 | cobN | 4e-06 | 28.00% (275) | cobaltochelatase subunit CobN |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M MAEPTILLLSTSDTDLICARSSGRAYRWANPARLSDLELADLLTDAAIVV
MUL_2277|M.ulcerans_Agy99 MAEPTILLLSTSDTDLICARSSGRAYRWANPARLSDLELADLLTDAAIVV
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------MR-AITALLTLLPLAICALSGCSARGTEPSPHEETTN-----
TH_3189|M.thermoresistible__bu ----MPARIRNARVTKLTATFAAVLTVTGCAGSAATSASPDTADG-----
Mflv_3882|M.gilvum_PYR-GCK ------MMPSRRCLSSVAAVMAALVSLTGCAASAP---PESGATS-----
MMAR_3037|M.marinum_M VRILGGYRAWEDGIEAVLAAGVPAVMVSGEQAADAELMDRSSVPAGIALQ
MUL_2277|M.ulcerans_Agy99 VRILGGYRAWEDGIEAVLTAGVPAVMVSGEQAADAELMDRSSVPAGIALQ
MAB_0547c|M.abscessus_ATCC_199 -------------MKALIGSVAALALLTTSCATIDEASTATDHVS-----
: . :: .
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------YPLTFENCGVTVTIDR--
TH_3189|M.thermoresistible__bu --------------------------------YPVQLENCGRTVSIPA--
Mflv_3882|M.gilvum_PYR-GCK --------------------------------AVVSVDNCGEQIRLEA--
MMAR_3037|M.marinum_M AHIYLAQGGVDNLRQLHSFLCDTVLMTGVGFGPPVAIPSWGVLRRPDAGS
MUL_2277|M.ulcerans_Agy99 AHVYLAQGGVDNLRQLHSFLCDTVLMTGVGFGPPVAIPSWGVLRRPDAGS
MAB_0547c|M.abscessus_ATCC_199 ------------------------------------VDNCGAPLQVPV--
. . *
MSMEG_4561|M.smegmatis_MC2_155 ------------------------------------PPQRVVSLYQASTE
TH_3189|M.thermoresistible__bu ------------------------------------PPQRAVSLNQGSTE
Mflv_3882|M.gilvum_PYR-GCK ------------------------------------PPQRAVGYFQQSVE
MMAR_3037|M.marinum_M TGPTIAVLYYRAQHLAGNTAYVEALCAAIEAAGGRALPVYCASLRTAEPE
MUL_2277|M.ulcerans_Agy99 AGPTIAVLYYRAQHLAGNTAYVEALCAAIEAAGGRALPAYCASLRTAEPE
MAB_0547c|M.abscessus_ATCC_199 ------------------------------------PVTRVVSNDTGVTE
.. *
MSMEG_4561|M.smegmatis_MC2_155 ILLSLGLADRMVGTSTWFDPVLPALAEDNAS-----VPRLADNDP-SLET
TH_3189|M.thermoresistible__bu ILLSLGLADRMVGTATWTDPVRENLAADNAG-----VERLADNHP-SLER
Mflv_3882|M.gilvum_PYR-GCK LMLALGLGESVVATVYPDNPPLPRYAEAYRS-----IPQLSNKDA-SFEQ
MMAR_3037|M.marinum_M LLTTLGSADAMVVTVLAAGGVKPATASAGGDDDSWNVEHLAALDIPILQG
MUL_2277|M.ulcerans_Agy99 LLTTLGSADAMVVTVLAAGGVKPATASAGGDDDSWNVEHLAALDIPILQG
MAB_0547c|M.abscessus_ATCC_199 LLFALGLQDRMAGYFLDSGQDRDISTSPWKAQ---FESTTNLGQGFTREA
:: :** : :. . : . :
MSMEG_4561|M.smegmatis_MC2_155 VLAAEPDLVTSASAHTFTPAVVAERARLGQLG------------------
TH_3189|M.thermoresistible__bu VLQTEPDLVTASFASTLGPGGVTTPEALEQLG------------------
Mflv_3882|M.gilvum_PYR-GCK VLSAAPDFVYGGYASAFDDTAGRSRRAFHDAG------------------
MMAR_3037|M.marinum_M LCLTSPRAQWCANDDGLSPLDVATQVAVPEFDGRIITVPFSFKEIDDDGL
MUL_2277|M.ulcerans_Agy99 LCLTSPRAQWCANDDGLSPLDVATQVAVPEFDGRIITVPFSFKEIDDDGL
MAB_0547c|M.abscessus_ATCC_199 VQTARPDLVFAGWNYGFSETSGLTPDWVRSIG------------------
: : * . : . . .
MSMEG_4561|M.smegmatis_MC2_155 VATYQSPSVCTGAE---------VDGETVTRTEPLTFDTLFDEINQLARM
TH_3189|M.thermoresistible__bu IPSYLSPADCIKNN---------DTDGDGSRDAALEMDTVYQEITDLAEI
Mflv_3882|M.gilvum_PYR-GCK VATYLNPEYCAT--------------------EPITMDDVHTEIRTIAAI
MMAR_3037|M.marinum_M IAYVADPERCDRVAGLALRHARLRGVDPADKRVALVFSAYPTKHARIGNA
MUL_2277|M.ulcerans_Agy99 IAYVADPERCDRVAGLALRHARLRGVDPADKRVALVFSAYPTKHARIGNA
MAB_0547c|M.abscessus_ATCC_199 AVPYQLTEACRQSG-------------TARRGIKAPLEALYEDLTNLGII
. * :. . :.
MSMEG_4561|M.smegmatis_MC2_155 FDVPE---------------------------RGARLVDDLQRR------
TH_3189|M.thermoresistible__bu FGVPD---------------------------RGAALVEELQTR------
Mflv_3882|M.gilvum_PYR-GCK FGVPE---------------------------RADALIEEMRDR------
MMAR_3037|M.marinum_M VGLDTPASAVALLRAMGERGYQVGELPGVEAADGDALIHALIERGGQDPD
MUL_2277|M.ulcerans_Agy99 VGLDTPASAVALLRAMGERGYQVGELPGVEAADGDALIHALIERGGQDPD
MAB_0547c|M.abscessus_ATCC_199 FGVQD---------------------------RARDLIASYRQT------
..: . *:
MSMEG_4561|M.smegmatis_MC2_155 -----------------------------LSEAS-LEPKPGTTVAYWFSG
TH_3189|M.thermoresistible__bu -----------------------------MAAAADTAPGAPVRVLFWFAN
Mflv_3882|M.gilvum_PYR-GCK -----------------------------VAAAAAAVDGVRTAKIFVYDS
MMAR_3037|M.marinum_M WLTEGQLSGNPIRVSAKDYRRWFATLPSELTDAVTQHWGPPPGELFVDRS
MUL_2277|M.ulcerans_Agy99 WLTEGQLSGNPIRVSAKDYRRWFATLPSELTDAVTQHWGPPPGELFVDRS
MAB_0547c|M.abscessus_ATCC_199 ----------------------------IEDVQSHAPHEQAPVRVFLYDS
: .
MSMEG_4561|M.smegmatis_MC2_155 LR-TPSMAGCCSAPGLYTAALGLANVFAD------------------ASE
TH_3189|M.thermoresistible__bu SE-SPYLAGCCGAPGIIARTLGLTNVFDD------------------TNA
Mflv_3882|M.gilvum_PYR-GCK GEDTAFTAGRQGIGNQIIELAGGTNIFGD------------------VED
MMAR_3037|M.marinum_M NDPDGEIVIAAMQSGNLVLMVQPPRGFGENPVAIYHDPDLPPSHHYLAAY
MUL_2277|M.ulcerans_Agy99 NDPDGEIVIAAMQSGNLVLMVQPPRGFGENPVAIYHDPDLPPSHHYLAAY
MAB_0547c|M.abscessus_ATCC_199 GDAEPFTSGRTAAPQQIIEKAGGRNIFSD------------------LND
. * :
MSMEG_4561|M.smegmatis_MC2_155 DWPEVSWEAVAARDP-----------DVLVLADLNRRRIDGDALDAKIGF
TH_3189|M.thermoresistible__bu EWPQVNWETVADRDP-----------DVLIIGDLTRKSQTAESAAAKIEF
Mflv_3882|M.gilvum_PYR-GCK TFADVSWEQVVQRNP-----------DVIVIYDYFG----TPSVEDKWAF
MMAR_3037|M.marinum_M HWLDAGFGAHAVVHLGKHGNLEWLPGKTLGMSAACGSDAALGNLPLIYPF
MUL_2277|M.ulcerans_Agy99 HWLDAGFGAHAVVHLGKHGNLEWLPGKTLGMSAACGSDAALGNLPLIYPF
MAB_0547c|M.abscessus_ATCC_199 SWTTSAWETAAQRDP-----------QVIIVCDYGVG--PNNTAQAKIDL
: : . . ..: : :
MSMEG_4561|M.smegmatis_MC2_155 LESNP---------------------------------------------
TH_3189|M.thermoresistible__bu LKSHP---------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK LRSRP---------------------------------------------
MMAR_3037|M.marinum_M LVNDPGEGTQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHANVA
MUL_2277|M.ulcerans_Agy99 LVNDPGEGIQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHANVA
MAB_0547c|M.abscessus_ATCC_199 LKAQP---------------------------------------------
* *
MSMEG_4561|M.smegmatis_MC2_155 --VTRHMTAVRNKRYVVLTGSELDPGIRQVQAVEK---------------
TH_3189|M.thermoresistible__bu --VTRELTAVREQRYIPLSGAAMNPSIRTVDGVEQ---------------
Mflv_3882|M.gilvum_PYR-GCK --ELAGVPAIRDDRYAVLTLQDAVLGVRAPYAVET---------------
MMAR_3037|M.marinum_M ALDPAKLPAIRQQIWTLIRAAKMDHDLGLTERPEEDCFDDMLLHVDGWLC
MUL_2277|M.ulcerans_Agy99 ALDPAKLPAIRQQIWTLIRAAKMDHDLGLTERPEEDCFDDMLLHVDGWLC
MAB_0547c|M.abscessus_ATCC_199 --LMRHTQAVRDENFIVLPYAALVEGPRNPDAIVT---------------
*:*:. : : .
MSMEG_4561|M.smegmatis_MC2_155 ------MAAGLESFGLVS--------------------------------
TH_3189|M.thermoresistible__bu ------VAAALREFGFGG--------------------------------
Mflv_3882|M.gilvum_PYR-GCK ------LARQVHPERFR---------------------------------
MMAR_3037|M.marinum_M EIKDVQIRDGLHILGQKPTGETELDLVLAILRARQLFAGAQALPGLRQAL
MUL_2277|M.ulcerans_Agy99 EIKDVQIRDGLHILGQKPTGETELDLVLAILRARQLFAGAQALPGLRQAL
MAB_0547c|M.abscessus_ATCC_199 ------LANYLRSKGF----------------------------------
: :.
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M GLAEDGTDERAAVDQTEAAARGLVAALQAADWDCAAVEQITDNPEVAAVL
MUL_2277|M.ulcerans_Agy99 GLAEDGTDERAAVDRIEAAARGLVSALQAADWDCAAVEQITDNPEAAAVL
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M RFAATEVVPRLAGTEAEIDQVLRALDGHFIAAGPSGSPLRGLVNVLPTGR
MUL_2277|M.ulcerans_Agy99 RFAATEVVPRLAGTEAEIDQVLRALDGHFIAVGPSGSPLRGLVNVLPTGR
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M NFYSVDPKAVPSRLAWEAGAALADSLLTRYRNDHGRWPQSVGLSVWGTSA
MUL_2277|M.ulcerans_Agy99 NFYSVDPKAVPSRLAWEAGAALADSLLTRYRNDHGRWPQSVGLSVWGTSA
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M MRTAGDDIAEVLALLGVRPVWDEASRRVVDLTPIALAELGRPRIDVTVRI
MUL_2277|M.ulcerans_Agy99 MRTAGDDIAEVLALLGVRPVWDEASRRVVDLTPIALAKLGRPRIDVTVRI
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M SGFFRDAFPHVVTMLDDAVRLVAELDEPAEDNYVRAHAQADLAQHGDQRR
MUL_2277|M.ulcerans_Agy99 SGFFRDAFPHVVTMLDDAVRLVAELDEPAEDNYVRAHAQADLAQHGDQRR
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M ATTRIFGSKPGTYGAGLLQLIDSRNWRDDADLAQVYTAWGGFAYGRDLEG
MUL_2277|M.ulcerans_Agy99 ATTRIFGSKPGTYGAGLLQLIDSRNWRDDADLAQVYTAWGGFAYGRDLEG
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M REAVDDMNRQYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVATVRALTG
MUL_2277|M.ulcerans_Agy99 REAVDDMDRQYRRIAVAAKNTDTREHDIADSDDYFQYHGGMVATVRALTG
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M QAPAAYIGDNTRPDAIRTRTLSEETTRVFRARVVNPRWMAAMRRHGYKGA
MUL_2277|M.ulcerans_Agy99 QAPAAYIGDNTRPDAIRTRTLSEETTRVFRARVVNPRWMAAMRRHGYKGA
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 --------------------------------------------------
TH_3189|M.thermoresistible__bu --------------------------------------------------
Mflv_3882|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3037|M.marinum_M FEMAATVDYLFGYDATAGVMADWMYEQLTERYVLDPENRKFMTESNPWAL
MUL_2277|M.ulcerans_Agy99 FEMAATIDYLFGYDATAGVMADWMYEQLTERYVLDPENRKFMTESNPWAL
MAB_0547c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4561|M.smegmatis_MC2_155 ----------------------------------------
TH_3189|M.thermoresistible__bu ----------------------------------------
Mflv_3882|M.gilvum_PYR-GCK ----------------------------------------
MMAR_3037|M.marinum_M HGMAERLLEAAGRGMWAQPQPETLDGLRQALLETEGDLEG
MUL_2277|M.ulcerans_Agy99 HGMAERLLEAAGRGMWAQPQPETLDGLRQALLETEGDLEG
MAB_0547c|M.abscessus_ATCC_199 ----------------------------------------