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M. smegmatis MC2 155 MSMEG_4496 (-)

annotation: putative metalloprotease
coordinates: 4576777 - 4577313
length: 178

SIEVSNESGYDVSEPELISVARFVIEKMDVHPAAELSMVLLDSAAMADLHMRWMDLPGPTDVMSFPMDEL
EPGGRPDAPEPGPAMLGDIVLCPEFAEQQAAKAGHSLGHELALLTVHGVLHLLGYDHAEPDEEKEMFALQ
RQLLEEWVADQVEAYHADRQSEKDRRLLDKSRYFDEP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4496--100% (178)putative metalloprotease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2388c-5e-9089.20% (176) putative metalloprotease
M. gilvum PYR-GCKMflv_2707-9e-9289.89% (178) putative metalloprotease
M. tuberculosis H37RvRv2367c-5e-9089.20% (176) putative metalloprotease
M. leprae Br4923MLBr_00628-5e-8585.71% (175) putative metalloprotease
M. abscessus ATCC 19977MAB_1669-3e-7777.97% (177) putative metalloprotease
M. marinum MMMAR_3677-1e-9088.76% (178) metal-dependent hydrolase
M. avium 104MAV_2026-1e-9191.48% (176) putative metalloprotease
M. thermoresistible (build 8)TH_1055-8e-9190.96% (177) UNKNOWN
M. ulcerans Agy99MUL_3620-8e-9188.76% (178) putative metalloprotease
M. vanbaalenii PYR-1Mvan_3831-7e-9189.83% (177) putative metalloprotease

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4496|M.smegmatis_MC2_155      -----MSIEVSNESGYDVSEPELISVARFVIEKMDVHPAAELSMVLLDSA
TH_1055|M.thermoresistible__bu      -----MSIEVSNESGIDVCEEELISVARFVIEKMNVHPAAELSMVLLDPA
MMAR_3677|M.marinum_M               -----MSIEVSNESGIDVSETELVSVARFVIGKMDVNPGAELSMVLLDTA
MUL_3620|M.ulcerans_Agy99           -----MSIEVSNESGIDVSETELVSVARFVIGKMDVNPGAELSMVLLDTA
MAV_2026|M.avium_104                -----MSIEVSNESGIDVSEAELISVARFVIAKMDVNPAAELSMVLLDTA
Mb2388c|M.bovis_AF2122/97           MREHLMSIEVANESGIDVSEAELVSVARFVIAKMDVNPCAELSMLLLDTA
Rv2367c|M.tuberculosis_H37Rv        MREHLMSIEVANESGIDVSEAELVSVARFVIAKMDVNPCAELSMLLLDTA
MLBr_00628|M.leprae_Br4923          -----MSVEVSNESGFDVSEVELVSVARFVIIKMDVNPAAELSMVLLDTA
Mflv_2707|M.gilvum_PYR-GCK          -----MSIEVSNESGIDVSESELVSVARFVIRKMDVNPAAELSMVLLDTA
Mvan_3831|M.vanbaalenii_PYR-1       -----MTIEVSNESGIDVSEEELISVARFVIGKMDVNPAAELSMLLLDTA
MAB_1669|M.abscessus_ATCC_1997      -----MSIEVVNESGIDVAEGELVSVARFAIAAMDVHPAAELSMMLVDLA
                                         *::** **** **.* **:*****.*  *:*:* *****:*:* *

MSMEG_4496|M.smegmatis_MC2_155      AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPAMLGDIVLCPE
TH_1055|M.thermoresistible__bu      AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAAEPGPAMLGDIVLCPE
MMAR_3677|M.marinum_M               AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPAMLGDIVLCPE
MUL_3620|M.ulcerans_Agy99           AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPAMLGDIVLCPE
MAV_2026|M.avium_104                AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPAMLGDIVLCPE
Mb2388c|M.bovis_AF2122/97           AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPSMLGDIVLCPE
Rv2367c|M.tuberculosis_H37Rv        AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPSMLGDIVLCPE
MLBr_00628|M.leprae_Br4923          AMADLHMRWMDLPGPTDVMSFPMDEFEPGGRPDAAEPGPSMLGDIVLCPE
Mflv_2707|M.gilvum_PYR-GCK          AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDTPEPGPSMLGDIVLCPE
Mvan_3831|M.vanbaalenii_PYR-1       AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPSMLGDIVLCPE
MAB_1669|M.abscessus_ATCC_1997      AMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPSMLGDIVLCPQ
                                    *************************:*******:.****:*********:

MSMEG_4496|M.smegmatis_MC2_155      FAEQQAAKAGHSLGHELALLTVHGVLHLLGYDHAEPDEEKEMFALQRQLL
TH_1055|M.thermoresistible__bu      FAAEQAAAAGHSLGQELALLTVHGVLHLLGYDHAEPEEEKEMFALQRRLL
MMAR_3677|M.marinum_M               FAAEQAAAAGHSLGHELALLTIHGVLHLLGYDHGEPDEEKEMFALQDRLL
MUL_3620|M.ulcerans_Agy99           FAAEQAAAAGHSLGHELALLTIHGVLHLLGYDHGEPDEEKEMFALQDRLL
MAV_2026|M.avium_104                FAADQAAAAGHSLGHELALLTIHGVLHLLGYDHGEPDEEKEMFALQDRLL
Mb2388c|M.bovis_AF2122/97           FAAEQAAAAGHSLGHELALLTIHGVLHLLGYDHAEPDEEKEMFALQDRLL
Rv2367c|M.tuberculosis_H37Rv        FAAEQAAAAGHSLGHELALLTIHGVLHLLGYDHAEPDEEKEMFALQDRLL
MLBr_00628|M.leprae_Br4923          FAAQQAAAEGHSLGHELALLTIHGVLHLLGYDHGEPDEEKEMFALQGRLL
Mflv_2707|M.gilvum_PYR-GCK          FAAKQAADAGHTLGQELALLTVHGVLHLLGYDHAEPDEEKEMFALQRELL
Mvan_3831|M.vanbaalenii_PYR-1       FAAKQAADAGHTLGQELALLTVHGVLHLLGYDHAEPDEEKEMFALQRELL
MAB_1669|M.abscessus_ATCC_1997      FAAEQAEAAGHSLAHELALLTVHGVLHLLGYDHAEPEEEREMFALQNQLL
                                    ** .**   **:*.:******:***********.**:**:****** .**

MSMEG_4496|M.smegmatis_MC2_155      EEWVADQVEAYHADRQSEKDRRLLDKSRYFDEP------
TH_1055|M.thermoresistible__bu      EEWVADQVEAYHQELQSEKDRRLLDKSRYFDQL------
MMAR_3677|M.marinum_M               EEWVAEQVQAYQQDRQDERDRRLLDKSRYFDEP------
MUL_3620|M.ulcerans_Agy99           EEWVAEQVQAYQQDRQDERDRRLLDKSRYFDEP------
MAV_2026|M.avium_104                EEWVADQVEAYHQDRQQERDRRLLDKSRYFDN-------
Mb2388c|M.bovis_AF2122/97           EEWVADQVEAYQHDRQDEKDRRLLDKSRYFDL-------
Rv2367c|M.tuberculosis_H37Rv        EEWVADQVEAYQHDRQDEKDRRLLDKSRYFDL-------
MLBr_00628|M.leprae_Br4923          EEWVAEQVRAYQHDRQNEKDCRLLYKSGYFGYL------
Mflv_2707|M.gilvum_PYR-GCK          EEWVAEQVEAYHLDRQNEKDRRLLDKSRYF------DTP
Mvan_3831|M.vanbaalenii_PYR-1       EEWVADQVQAYHQDRQSQKDQRLLDKSRYFDELNHGDTP
MAB_1669|M.abscessus_ATCC_1997      QDWYEQQAQLY-------RDSRLLDKSRNFDE-------
                                    ::*  :*.. *       :* *** **  *