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M. tuberculosis H37Rv Rv2232 (-)

annotation: hypothetical protein Rv2232
coordinates: 2506278 - 2507153
length: 291

VSSPRERRPASQAPRLSRRPPAHQTSRSSPDTTAPTGSGLSNRFVNDNGIVTDTTASGTNCPPPPRAAAR
RASSPGESPQLVIFDLDGTLTDSARGIVSSFRHALNHIGAPVPEGDLATHIVGPPMHETLRAMGLGESAE
EAIVAYRADYSARGWAMNSLFDGIGPLLADLRTAGVRLAVATSKAEPTARRILRHFGIEQHFEVIAGAST
DGSRGSKVDVLAHALAQLRPLPERLVMVGDRSHDVDGAAAHGIDTVVVGWGYGRADFIDKTSTTVVTHAA
TIDELREALGV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2232--100% (291)hypothetical protein Rv2232

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2257-1e-166100.00% (291) hypothetical protein Mb2257
M. gilvum PYR-GCKMflv_2889-1e-7964.71% (221) HAD family hydrolase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1901c-6e-7162.33% (215) hypothetical protein MAB_1901c
M. marinum MMMAR_3308-1e-8975.24% (210) hypothetical protein MMAR_3308
M. avium 104MAV_2207-3e-8774.55% (220) hypothetical protein MAV_2207
M. smegmatis MC2 155MSMEG_4308-2e-8670.18% (218) 5'-nucleotidase
M. thermoresistible (build 8)TH_1464-3e-8766.39% (241) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1320-2e-5575.56% (135) hypothetical protein MUL_1320
M. vanbaalenii PYR-1Mvan_3621-2e-8267.42% (221) HAD family hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2889|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3621|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv2232|M.tuberculosis_H37Rv         MSSPRERRPASQAPRLSRRPPAHQTSRSSPDTTAPTGSGLSNRFVNDNGI
Mb2257|M.bovis_AF2122/97            MSSPRERRPASQAPRLSRRPPAHQTSRSSPDTTAPTGSGLSNRFVNDNGI
MMAR_3308|M.marinum_M               --------------------------------------------------
MUL_1320|M.ulcerans_Agy99           --------------------------------------------------
MAV_2207|M.avium_104                --------------------------------------------------
TH_1464|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4308|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1901c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_2889|M.gilvum_PYR-GCK          MTDMLDGTRRVAP------------VGRGDLVLFDLDGTLTDSAEGIVAS
Mvan_3621|M.vanbaalenii_PYR-1       MTDMLDGTRDLAP------------VERGDVVIFDLDGTLTDSAEGIVAS
Rv2232|M.tuberculosis_H37Rv         VTDTTASGTNCPPPPRAAARRASSPGESPQLVIFDLDGTLTDSARGIVSS
Mb2257|M.bovis_AF2122/97            VTDTTASGTNCPPPPRAAARRASSPGESPQLVIFDLDGTLTDSARGIVSS
MMAR_3308|M.marinum_M               -------------------------------MIFDLDGTLTDSAHGIVAS
MUL_1320|M.ulcerans_Agy99           --------------------------------------------------
MAV_2207|M.avium_104                MTGTTSADPAAP---------------AAQLVIFDLDGTLTDSAEGIVAS
TH_1464|M.thermoresistible__bu      VTETRDDTAAVPAGAVDAARRPVDPALRPELVIFDLDGTLTDSAEGIVSS
MSMEG_4308|M.smegmatis_MC2_155      MTDVVTGRVSELTP-----------DTRPQLVLFDLDGTLTDSAEGIVSS
MAB_1901c|M.abscessus_ATCC_199      -----------------------------MLVIFDLDGTLTDSAPGIVSS
                                                                                      

Mflv_2889|M.gilvum_PYR-GCK          FRHALQSVGAAVPDGDLVSKIVGPPMPLTFQRMGLGDLVDDAIAAYRADY
Mvan_3621|M.vanbaalenii_PYR-1       FRHALHAVGAPVPDGDLVSRIVGPPMHVTLQQMGLGEHADAAIAAYRADY
Rv2232|M.tuberculosis_H37Rv         FRHALNHIGAPVPEGDLATHIVGPPMHETLRAMGLGESAEEAIVAYRADY
Mb2257|M.bovis_AF2122/97            FRHALNHIGAPVPEGDLATHIVGPPMHETLRAMGLGESAEEAIVAYRADY
MMAR_3308|M.marinum_M               FRHALNHIGAAVPDGDLVAQIVGPPMDDTFHAMELGDRVEDAIAAFRAEY
MUL_1320|M.ulcerans_Agy99           --------------------------------------------------
MAV_2207|M.avium_104                FLHALESIGAPVPPGDLVAQIVGPPMDDTFRSMQLGEDAEAAIAAFRAEY
TH_1464|M.thermoresistible__bu      FRHALASVGAAVPDGDLAARIIGPPMHHTLRSLGLGDQTDAAIDAYRQDY
MSMEG_4308|M.smegmatis_MC2_155      FRHALQAVGAPVPDGDLASRIVGPPMHHTLTSLGLGDQADEAIAAYRADY
MAB_1901c|M.abscessus_ATCC_199      FRHALSHVGAPEPTGDIASRVVGPPMHITLGSMGLGERADDAIAAYRADY
                                                                                      

Mflv_2889|M.gilvum_PYR-GCK          TTRGWSMNRPFDGIPALLADLQAAGVRMAVATSKAETTAQRILAHFGLDG
Mvan_3621|M.vanbaalenii_PYR-1       VSRGWAMNQPFTGIPALLADLQAAGVRMAVATSKAEPTAQRILAHFGLDG
Rv2232|M.tuberculosis_H37Rv         SARGWAMNSLFDGIGPLLADLRTAGVRLAVATSKAEPTARRILRHFGIEQ
Mb2257|M.bovis_AF2122/97            SARGWAMNSLFDGIGPLLADLRTAGVRLAVATSKAEPTARRILRHFGIEQ
MMAR_3308|M.marinum_M               GARGWAMNTLFDGIAPLLADLRAAGVRLAVATCKLEPTARRVLAHFGLDA
MUL_1320|M.ulcerans_Agy99           ------MNTLFDGIAPLLADLRAAGVRLAVATCKLEPTARRVLAHFGLDA
MAV_2207|M.avium_104                GARGWAMNTLFDGIEALLADLRAAGVRLAVATSKLEPTARRILAHFGLDH
TH_1464|M.thermoresistible__bu      RARGWAMNRVYDGIPELLADLRAAEVRLAVATSKAEPTAQRILAHFGLAD
MSMEG_4308|M.smegmatis_MC2_155      TSRGWAMNSLFDGIPALLSDLRAAGVRLAVATSKAEPTARRILEHFELDG
MAB_1901c|M.abscessus_ATCC_199      GERGWAVNEMFDGIRDVLTRLREAGVPMVVATSKSEPIAARILEHFGLAE
                                          :*  : **  :*: *: * * :.***.* *. * *:* ** :  

Mflv_2889|M.gilvum_PYR-GCK          HFEVIAGASNDGTRAAKSDVVAHALAQLAPVPDN-VVMIGDRSHDVEGAA
Mvan_3621|M.vanbaalenii_PYR-1       HFEVIAGAGADGTRAAKADVVARALEQLAPVPQR-MVMIGDRSHDVEGAA
Rv2232|M.tuberculosis_H37Rv         HFEVIAGASTDGSRGSKVDVLAHALAQLRPLPER-LVMVGDRSHDVDGAA
Mb2257|M.bovis_AF2122/97            HFEVIAGASTDGSRGSKVDVLAHALAQLRPLPER-LVMVGDRSHDVDGAA
MMAR_3308|M.marinum_M               HFEVIAGATGDGARRSKTEVLAHALAQLHPLPER-VLMVGDRSHDVEGAA
MUL_1320|M.ulcerans_Agy99           HFEVIAGATGDGARRSKTEVLAHALAQLHPLPER-VLMVGDRSHDVEGAT
MAV_2207|M.avium_104                HFEVIAGASPDGSRKAKVEVLAHALAQLEPLPER-VLMVGDRSHDVHGAA
TH_1464|M.thermoresistible__bu      HFEFIAGASVDGSRAAKADVLARALQALQPLPER-VLMVGDRCHDVEGAA
MSMEG_4308|M.smegmatis_MC2_155      YFEVIAGASPDGTRSLKSEVVAHALRQLEPLPDR-VLMVGDRMHDVEGAA
MAB_1901c|M.abscessus_ATCC_199      FFQVIAGASPDGVRSSKADVIKHALSQLDDVPPTGVVMVGDRVHDVEGAA
                                    .*:.****  ** *  * :*: :**  *  :*   ::*:*** ***.**:

Mflv_2889|M.gilvum_PYR-GCK          VHGIATIVVGWGYGRTDFAG----RESGALAHVTDVDDLREVLGV
Mvan_3621|M.vanbaalenii_PYR-1       VHGIGTIVVGWGYGGRDFAD----GDGGALAHVADIDDLREVLGV
Rv2232|M.tuberculosis_H37Rv         AHGIDTVVVGWGYGRADFIDK---TSTTVVTHAATIDELREALGV
Mb2257|M.bovis_AF2122/97            AHGIDTVVVGWGYGRADFIDK---TSTTVVTHAATIDELREALGV
MMAR_3308|M.marinum_M               AHGIDTVVVGWGYGKADFAAG---THSGAALHAGTVDELREALGV
MUL_1320|M.ulcerans_Agy99           AHGIDTVVVGWGYGKADFAAG---THSGAALHAGTVDELREALGV
MAV_2207|M.avium_104                AHGIDTVVVGWGYGHAD-------SHPDGVTRAATIDELRRALGV
TH_1464|M.thermoresistible__bu      AHGIDTVVVGWGYGRDDFAHE---DAIPAYAHVATVAELREVLSV
MSMEG_4308|M.smegmatis_MC2_155      EHGIDTVVVGWGYGGADFSGP---AAVVAHAHVETVEALRGVLGV
MAB_1901c|M.abscessus_ATCC_199      AHGIGTVVVDWGYGATDFEGDPGQLAEWIIGRVSTPEQLLEELDV
                                     *** *:**.****  *              :.     *   *.*