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M. smegmatis MC2 155 MSMEG_4304 (-)

annotation: regulatory protein
coordinates: 4394755 - 4395333
length: 192

VDAPGAEHDVDALVRQRLRELRTERGLTLEDVASRAQIDVSTLSRLESGKRRLALDHLPRLATALSVTTD
DLLRAPEAEDPRVRGTATTRDNITYWPLTRHGPANGLHAYKIRISEQRNTPPAELPVHEGRDWMYVLSGK
LRLILGEQDFTVGPGEAVEFSTWTPHWFGVVDGPVEAVTIFGLHGEQVHLHS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4304--100% (192)regulatory protein
M. smegmatis MC2 155MSMEG_6265-1e-1025.53% (188) transcriptional regulator
M. smegmatis MC2 155MSMEG_1151-1e-0828.41% (176) DNA-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2893-7e-7575.90% (166) XRE family transcriptional regulator
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3176c-4e-3445.20% (177) hypothetical protein MAB_3176c
M. marinum MMMAR_2152-1e-0827.45% (153) transcriptional regulator
M. avium 104MAV_2214-2e-8375.40% (187) regulatory protein
M. thermoresistible (build 8)TH_0145-8e-8273.82% (191) regulatory protein
M. ulcerans Agy99MUL_1737-4e-0927.45% (153) transcriptional regulator
M. vanbaalenii PYR-1Mvan_3617-1e-8478.69% (183) XRE family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2893|M.gilvum_PYR-GCK          ---------------------------MTLEDVATRSSIDISTLSRLESG
Mvan_3617|M.vanbaalenii_PYR-1       -MKANEEDDGVDARVRRRLRDLRLQRGMTLEDVATRSNIDISTLSRLESG
TH_0145|M.thermoresistible__bu      -MEANQREGRIEDRIRQRLRELRKQRGLTLEDVATRAQIDVSTLSRLESG
MAV_2214|M.avium_104                -MQAN---TDIDVQVRRRLRELRVQRGLTLQEVGARAGIDVSTLSRLESG
MSMEG_4304|M.smegmatis_MC2_155      -MDAPGAEHDVDALVRQRLRELRTERGLTLEDVASRAQIDVSTLSRLESG
MAB_3176c|M.abscessus_ATCC_199      MDDQNRRMEAVLDALGPRLRALRLHRQITLAQLSETTGISESTLSRLESG
MMAR_2152|M.marinum_M               --------------MTALLRAVRRQRGLTLEQLAQRAGLTKSYLSKIERG
MUL_1737|M.ulcerans_Agy99           --------------MTALLRAVRRQRGLTLEQLAQRAGLTKSYLSKIERG
                                                               :** ::.  : :  * **::* *

Mflv_2893|M.gilvum_PYR-GCK          KRRLALDHLPRLAGALSVSTDELLRAPEIDDPRIRGQSHTHNQI---TFW
Mvan_3617|M.vanbaalenii_PYR-1       KRRLALDHLPRLASALSVSTDELLRAPEVEDPRVRGNSHTHNLI---TFW
TH_0145|M.thermoresistible__bu      KRRLAIDHLPRLAAALSVSTDDLLRAPDTEDPRVRGSAHTSHGV---TYW
MAV_2214|M.avium_104                KRRLALDHLPRLARALSVSTDELLQPAQAPDPRVRGSAHTHHGV---TYW
MSMEG_4304|M.smegmatis_MC2_155      KRRLALDHLPRLATALSVTTDDLLRAPEAEDPRVRGTATTRDNI---TYW
MAB_3176c|M.abscessus_ATCC_199      QRRPTLELLLLLAEAHQVPLDELVNAPATGDPRVHPKPFKRNGS---IYL
MMAR_2152|M.marinum_M               QSTPSIAVALKVARALDVDVGRLFSDESAHETITVDRAHDRLGPQSGRYH
MUL_1737|M.ulcerans_Agy99           QSTPSIAVALKVARALDVDVGRLFSDESAHETITADRAHDRLGPQSGRYH
                                    :   ::     :* * .*  . *.      :.     .          : 

Mflv_2893|M.gilvum_PYR-GCK          PLTAQGPAGGLHAHKIRISA-RRRTPPKELPVHEGHDWMYVLSGRLRLIL
Mvan_3617|M.vanbaalenii_PYR-1       PLTGQGPAGGLHAYKIRISA-RRRTPPAELPVHEGHDWMYVLSGRLRLML
TH_0145|M.thermoresistible__bu      PLTRQGPAGGLHAFKIRISA-RRRTPPAGLPVHEGHDWVYVLSGHMRLIL
MAV_2214|M.avium_104                PLTRQGPAGGLHAFKIRVSA-QRRTPPAELPVHEGQDWMYVLAGRMRLIL
MSMEG_4304|M.smegmatis_MC2_155      PLTRHGPANGLHAYKIRISE-QRNTPPAELPVHEGRDWMYVLSGKLRLIL
MAB_3176c|M.abscessus_ATCC_199      PLSRR--PGGIQCFKQIIPP-HSPKGEPNLKVHDGYEWMYVLAGNLRLLL
MMAR_2152|M.marinum_M               VLASTQLGKTMSPFVVRPTAGQDCASDGPHPEHTGQEFVFVHTGSVELDY
MUL_1737|M.ulcerans_Agy99           VLASTQLGKTMSPFVVRPTAGQDCASDGPHPEHTGQEFVFVHTGSVELDY
                                     *:       :  .    .  :          * * ::::* :* :.*  

Mflv_2893|M.gilvum_PYR-GCK          GDRDFTIKPGEAVEFSTWTPHWFG-AVDEPVEAIALLGLHGERVHLHTDH
Mvan_3617|M.vanbaalenii_PYR-1       GDRDFTIKPGEAVEFSTWTPHWFG-VVDGPVEAIMLLGLHGERVHLHSDQ
TH_0145|M.thermoresistible__bu      DSRDFVIKPGEAVEFSTWTPHWFG-AVDGPVEAIMILGPHGERLHLHE--
MAV_2214|M.avium_104                GDRDFTIDPGEAVEFSTWTPHWFG-VVDGPVEAIVIFGPHGERLHLHS--
MSMEG_4304|M.smegmatis_MC2_155      GEQDFTVGPGEAVEFSTWTPHWFG-VVDGPVEAVTIFGLHGEQVHLHS--
MAB_3176c|M.abscessus_ATCC_199      GELDLILPAGEAAEFDTHIPHWFGNPTDKPVEVLHIFGPQGERMHVRARS
MMAR_2152|M.marinum_M               GDQTITLGTGDSAYFDASVGHKLRAVGTERAEVVVVAGAELGGR------
MUL_1737|M.ulcerans_Agy99           GDQTITLGTGDSAYFDASVGHKLRAVGTERAEVVVVAGAELGGR------
                                    ..  : : .*::. *.:   * :       .*.: : * .          

Mflv_2893|M.gilvum_PYR-GCK          R---
Mvan_3617|M.vanbaalenii_PYR-1       R---
TH_0145|M.thermoresistible__bu      ----
MAV_2214|M.avium_104                ----
MSMEG_4304|M.smegmatis_MC2_155      ----
MAB_3176c|M.abscessus_ATCC_199      GSGN
MMAR_2152|M.marinum_M               ----
MUL_1737|M.ulcerans_Agy99           ----