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MGKAKPNDNKALVDAMLGDLGSRIRMLRKERQLTTERLAETAGVSAGLISQIERGNGNPSFATLVQLAHG LQMPIGQLLEAPESKSVVVRKNERRRLDGHGLANDDGGSYELLTPDLNGALEATWVVTPPGYDTSATPYH HHGEEFGIVLSGTKDVYLDGIRHRLHAGDSIRYASNIPHWYVNPSETEECTAIWVSTPPTW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1151 | - | - | 100% (201) | DNA-binding protein |
| M. smegmatis MC2 155 | MSMEG_1139 | - | 3e-13 | 27.93% (179) | transcription regulator |
| M. smegmatis MC2 155 | MSMEG_6265 | - | 8e-10 | 28.65% (178) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0484 | - | 2e-05 | 41.82% (55) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1295 | - | 3e-09 | 28.18% (181) | XRE family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0474 | - | 2e-05 | 41.82% (55) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3176c | - | 3e-17 | 29.67% (182) | hypothetical protein MAB_3176c |
| M. marinum M | MMAR_2152 | - | 1e-12 | 28.30% (159) | transcriptional regulator |
| M. avium 104 | MAV_3453 | - | 5e-11 | 28.48% (158) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_0145 | - | 4e-09 | 27.88% (165) | regulatory protein |
| M. ulcerans Agy99 | MUL_1737 | - | 5e-13 | 28.30% (159) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0450 | - | 2e-11 | 28.03% (157) | XRE family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2152|M.marinum_M --------------------------------------MTALLRAVRRQR
MUL_1737|M.ulcerans_Agy99 --------------------------------------MTALLRAVRRQR
MAV_3453|M.avium_104 --------------------------------------MTALLRPVRRQR
Mvan_0450|M.vanbaalenii_PYR-1 --------------------------------------MSGLLRAVRQER
MAB_3176c|M.abscessus_ATCC_199 ------------------------MDDQNRRMEAVLDALGPRLRALRLHR
TH_0145|M.thermoresistible__bu -------------------------MEANQREGRIEDRIRQRLRELRKQR
Mb0484|M.bovis_AF2122/97 -----------------MSSEEKLAAKVSTKASDVASDIGSFIRSQRETA
Rv0474|M.tuberculosis_H37Rv -----------------MSSEEKLAAKVSTKASDVASDIGSFIRSQRETA
MSMEG_1151|M.smegmatis_MC2_155 -------------------MGKAKPNDNKALVDAMLGDLGSRIRMLRKER
Mflv_1295|M.gilvum_PYR-GCK MANQNDRDDHTPLLRNTSGTARDRDPGAPVEELEIESAIGRNVRLLRQQQ
: :* *
MMAR_2152|M.marinum_M GLTLEQLAQRAGLTKSYLSKIERGQSTPSIAVALKVARALDVDVGRLFSD
MUL_1737|M.ulcerans_Agy99 GLTLEQLAQRAGLTKSYLSKIERGQSTPSIAVALKVARALDVDVGRLFSD
MAV_3453|M.avium_104 GLTLEALAAQTGLTKSYLSKIERGQSTPSIAVALKVARALDVDVGRLFSD
Mvan_0450|M.vanbaalenii_PYR-1 GMTLDDLAADTGLTKSYLSKVERGQSVPSIAAALKISRALEVDVAQLFSD
MAB_3176c|M.abscessus_ATCC_199 QITLAQLSETTGISESTLSRLESGQRRPTLELLLLLAEAHQVPLDELVNA
TH_0145|M.thermoresistible__bu GLTLEDVATRAQIDVSTLSRLESGKRRLAIDHLPRLAAALSVSTDDLLRA
Mb0484|M.bovis_AF2122/97 HVSMRQLAERSGVSNPYLSQVERGLRKPSADVLSQIAKALRVSAEVLYVR
Rv0474|M.tuberculosis_H37Rv HVSMRQLAERSGVSNPYLSQVERGLRKPSADVLSQIAKALRVSAEVLYVR
MSMEG_1151|M.smegmatis_MC2_155 QLTTERLAETAGVSAGLISQIERGNGNPSFATLVQLAHGLQMPIGQLLEA
Mflv_1295|M.gilvum_PYR-GCK GLTVAETAARVGISKAMMSKIENAQTSCSLSTLALLAKGFDVPVTSLFRG
:: : : :*::* . : :: . : *
MMAR_2152|M.marinum_M ESAHETITVDRAHDRLG------PQSGRYHVL-ASTQLGKTMSPFVVRPT
MUL_1737|M.ulcerans_Agy99 ESAHETITADRAHDRLG------PQSGRYHVL-ASTQLGKTMSPFVVRPT
MAV_3453|M.avium_104 EAAREKIAVERAG---G------PGGRRYRVL-ASSMLGKTMSPFVIRPT
Mvan_0450|M.vanbaalenii_PYR-1 DPEVSTISVDRAAER---------GADRHHAV-AARMLGKEMSPFVVRPG
MAB_3176c|M.abscessus_ATCC_199 PATGDPRVHPKPFKR---------NGSIYLPL-SRR--PGGIQCFKQIIP
TH_0145|M.thermoresistible__bu PDTEDPRVRGSAHTS---------HGVTYWPL-TRQGPAGGLHAFKIRIS
Mb0484|M.bovis_AF2122/97 AGILEPSETSQVRDA-----------------------------------
Rv0474|M.tuberculosis_H37Rv AGILEPSETSQVRDA-----------------------------------
MSMEG_1151|M.smegmatis_MC2_155 PESKSVVVRKNERRRLDGHGLANDDGGSYELL-TPDLNGALEATWVVTPP
Mflv_1295|M.gilvum_PYR-GCK ADVERPAAFVKAGTGARIVREGTREGHEYQLLGSLRGEHKRLECLEVTLS
MMAR_2152|M.marinum_M AGQDCASDGPHPEHTGQEFVFVHTGSVELDYGDQTITLGTGDSAYFDASV
MUL_1737|M.ulcerans_Agy99 AGQDCASDGPHPEHTGQEFVFVHTGSVELDYGDQTITLGTGDSAYFDASV
MAV_3453|M.avium_104 ---EQLADDPHPEHAGQEFLFVHAGRVELDYGDQTFTLGPGDSAYFDASV
Mvan_0450|M.vanbaalenii_PYR-1 ---RTFTTHPHPTHLGQEFIFVHSGRVELSHDGRIIALEAGDCAYFDASA
MAB_3176c|M.abscessus_ATCC_199 -PHSPKGEPNLKVHDGYEWMYVLAGNLRLLLGELDLILPAGEAAEFDTHI
TH_0145|M.thermoresistible__bu -ARRRTPPAGLPVHEGHDWVYVLSGHMRLILDSRDFVIKPGEAVEFSTWT
Mb0484|M.bovis_AF2122/97 ----IITDTAITERQKQILLDIYASFTHQNEATR--EECPSDPTPTDD--
Rv0474|M.tuberculosis_H37Rv ----IITDTAITERQKQILLDIYASFTHQNEATR--EECPSDPTPTDD--
MSMEG_1151|M.smegmatis_MC2_155 ---GYDTSATPYHHHGEEFGIVLSGTKDVYLDGIRHRLHAGDSIRYASNI
Mflv_1295|M.gilvum_PYR-GCK ---EKSQTYPLFQHPGTEFIYMLEGVMDYSHSRSVYRLQPGDSLQIDGEG
: : . ..:
MMAR_2152|M.marinum_M GHKLRAVGTERAEVVVVAG--AELGGR--------
MUL_1737|M.ulcerans_Agy99 GHKLRAVGTERAEVVVVAG--AELGGR--------
MAV_3453|M.avium_104 SHKVRSVGPEPAEVVAVAH--AEPGSAAFAG----
Mvan_0450|M.vanbaalenii_PYR-1 PHKLRQIGEDAAEVVVVAGNAPRPGAPRRRG----
MAB_3176c|M.abscessus_ATCC_199 PHWFGNPTDKPVEVLHIFGPQGERMHVRARSGSGN
TH_0145|M.thermoresistible__bu PHWFG-AVDGPVEAIMILGPHGERLHLHE------
Mb0484|M.bovis_AF2122/97 -----------------------------------
Rv0474|M.tuberculosis_H37Rv -----------------------------------
MSMEG_1151|M.smegmatis_MC2_155 PHWYVNPSETEECTAIWVSTPPTW-----------
Mflv_1295|M.gilvum_PYR-GCK AHGPVDLVEVPIRFLSVIAFPDSQV----------