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YAIEVAETGGPEVLSFVERPQPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVGTEVCGVIEAVG EGVAALKVGDRVVTDKSLGAYAEYCLAPADFVAYVPDGVAPEVAASALLKGMTAHYLIKSTYPVQQGDVV LLHAGAGGVGLILTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDYPDDPKAFGDRIRELTDGDGVAA VFDGVGASTFEASLASLAVRGTLALFGAASGPVPPVDPQRLNAAGSVYLTRPNLAHYTRTPDEFSWRAGE LLTAIADGTLDVTVSHRYALRDAEQAHRDLQGRKTVGSVVLLP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2724 | - | - | 100% (324) | alcohol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1864 | - | 8e-39 | 35.47% (327) | alcohol dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4202 | - | 3e-35 | 31.90% (326) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1489c | qor | 1e-130 | 71.34% (328) | quinone reductase |
| M. gilvum PYR-GCK | Mflv_3686 | - | 1e-164 | 87.50% (328) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv1454c | qor | 1e-130 | 71.34% (328) | quinone reductase |
| M. leprae Br4923 | MLBr_00118 | - | 6e-30 | 31.55% (336) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_2757 | - | 1e-106 | 59.20% (326) | quinone reductase Qor |
| M. marinum M | MMAR_2259 | qor | 1e-133 | 70.82% (329) | quinone reductase Qor |
| M. avium 104 | MAV_3325 | - | 1e-135 | 73.77% (324) | quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3106 | - | 1e-149 | 78.53% (326) | quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_3440 | - | 1e-153 | 80.86% (324) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. ulcerans Agy99 | MUL_1855 | qor | 1e-130 | 69.91% (329) | quinone reductase Qor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1489c|M.bovis_AF2122/97 -----------------------------------------------MHA
Rv1454c|M.tuberculosis_H37Rv -----------------------------------------------MHA
MMAR_2259|M.marinum_M ----------------------------------------MVGHDSGVHA
MUL_1855|M.ulcerans_Agy99 ----------------------------------------MVGHDSGVHA
MAV_3325|M.avium_104 -----------------------------------------------MHA
Mvan_2724|M.vanbaalenii_PYR-1 -----------------------------------------------MYA
Mflv_3686|M.gilvum_PYR-GCK --------------------------------------------MVDMYA
TH_3440|M.thermoresistible__bu VQTAAAQRRDEIGVIGVALRAVRTTGQNDPRMEHIRAGELHTGMIGAMKA
MSMEG_3106|M.smegmatis_MC2_155 -------------------------------MEHIRTGELHEWMIGGVHA
MAB_2757|M.abscessus_ATCC_1997 -----------------------------------------------MRA
MLBr_00118|M.leprae_Br4923 -----------------------------------------------MHA
: *
Mb1489c|M.bovis_AF2122/97 IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPR
Rv1454c|M.tuberculosis_H37Rv IEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPR
MMAR_2259|M.marinum_M IEVSQTGGPEVLSYVERPQPEPGHGELVIKAEAIGVNFIDTYFRSGSYPR
MUL_1855|M.ulcerans_Agy99 IEVSQTGGPEVLSYVERPQPEPGHGELVIKAEAIGVNFIDTYFRSGSYPR
MAV_3325|M.avium_104 IEVSETGGPEVLRYVETPTPTAGPGQVLIKAEAIGVNYIDTYFRSGQYPR
Mvan_2724|M.vanbaalenii_PYR-1 IEVAETGGPEVLSFVERPQPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
Mflv_3686|M.gilvum_PYR-GCK IEVAETGGPEVLSFVETSRPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
TH_3440|M.thermoresistible__bu IEVRETGGPEVLTYVDVPEPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPR
MSMEG_3106|M.smegmatis_MC2_155 IEVAETGGPEVLNYIERPEPSPGPGEVLIKADAIGVNFIDTYFRSGLYPR
MAB_2757|M.abscessus_ATCC_1997 IEVPVTGGPEVLTLVEKTDPAPGPGEVLIDVDAVGVNFRDIYLRNGSYTA
MLBr_00118|M.leprae_Br4923 IVAESAN---QMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGKYPH
* . :. : : . .* *:::*.. * *** * * *.
Mb1489c|M.bovis_AF2122/97 --ELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSASANGAYAEFC
Rv1454c|M.tuberculosis_H37Rv --ELPFVIGSEVCGTVEAVGPGVTAADT-AISVGDRVVSASANGAYAEFC
MMAR_2259|M.marinum_M --ELPFVIGSEVCGTVVALGPGATAADAGGIAVGDRVVSASANGGYAEFC
MUL_1855|M.ulcerans_Agy99 --ELPFVIGSEVCGTVVAVGPGATAADAGGIAVGDRVVSASANGGYAEFC
MAV_3325|M.avium_104 --ELPFIIGQELCGTVAAAGDGVD-----GFKVGDRVVSAAATGGYAEYA
Mvan_2724|M.vanbaalenii_PYR-1 --EVPFVVGTEVCGVIEAVGEGVA-----ALKVGDRVVTDKSLGAYAEYC
Mflv_3686|M.gilvum_PYR-GCK --ETPFIAGSEVCGVIEEVGEDVA-----ALNVGDRVVTTQSQGAYAEYC
TH_3440|M.thermoresistible__bu --EVPFIVGTEVCGTVEAVGDGVA-----ALRVGDRVLTDKANGAYAEYT
MSMEG_3106|M.smegmatis_MC2_155 --ELPFVVGTEVCGTVAAIGNDVA-----ALKVGDRVVTANAVGAYADYC
MAB_2757|M.abscessus_ATCC_1997 --PLPHIPGSEVSGVVRAVGEGVQ-----SLAPGDRVASPVAAWGYAEST
MLBr_00118|M.leprae_Br4923 PPGASAIIGMEVAGVVAAVSSGVT-----EWSVGQEVCALLAGGGYAEYV
. : * *:.*.: . .. *:.* : : .**:
Mb1489c|M.bovis_AF2122/97 TAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAG
Rv1454c|M.tuberculosis_H37Rv TAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVKRGDTVLVHAG
MMAR_2259|M.marinum_M TAPAALTAKVPDGVSAEVAASALLKGLTAHYLLKSVYPVADGDAILVHAG
MUL_1855|M.ulcerans_Agy99 TAPAALTAKVPDVVSAEVAASALLKGLTAHYLLKSVCPVADGDAILVHAG
MAV_3325|M.avium_104 TAPASLTAHVPDGVAADVAASALLKGLTAHYLLTSVYPVQAGDTVLVHAG
Mvan_2724|M.vanbaalenii_PYR-1 LAPADFVAYVPDGVAPEVAASALLKGMTAHYLIKSTYPVQQGDVVLLHAG
Mflv_3686|M.gilvum_PYR-GCK VAPADFVAYVPDAVAPEVAASALLKGMTAHYLLKSTYPVQQGDAILVHAG
TH_3440|M.thermoresistible__bu VAPADYVAYVPDGVAPDTVASALLKGMTAHYLIKSVYEVQRGDTILVHAG
MSMEG_3106|M.smegmatis_MC2_155 VAPADFVAYVPDGVAPEAVASALLKGMTAHYLLKSTYPVQPSDTVLVHAG
MAB_2757|M.abscessus_ATCC_1997 TAPADYTAKVPAGLSAEVAASSLLQGITTHYLLTSVYPVAAGDTVLVHAG
MLBr_00118|M.leprae_Br4923 AVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHGG
.** . :* : *. . *. : . : .: :*:*.*
Mb1489c|M.bovis_AF2122/97 AGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPED----
Rv1454c|M.tuberculosis_H37Rv AGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDAGADVVLDYPED----
MMAR_2259|M.marinum_M AGGVGLILTQWATHLGARVISTVSTPEKAKLSRDAGAAEVLDYPTD----
MUL_1855|M.ulcerans_Agy99 AGGVGLILTQWATHLGARVISTVSTPEKAKLSRDAGATEVLDYPTD----
MAV_3325|M.avium_104 AGGVGLILTQWAHLLGARVITTVSTPEKARRSAQAGANEVLSYPDD----
Mvan_2724|M.vanbaalenii_PYR-1 AGGVGLILTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDYPDD----
Mflv_3686|M.gilvum_PYR-GCK AGGVGLLLTQWATSLAASVITTVSTPDKAELSRRAGAVEVLDYPSQDAGG
TH_3440|M.thermoresistible__bu AGGVGLILTQWATHLGARVITTVSTPQKAELSRKAGAAEVLDYPTD----
MSMEG_3106|M.smegmatis_MC2_155 AGGVGLILTQWATSLGTRVITTASTPEKAELSRQAGAVEVLDYPDPD--D
MAB_2757|M.abscessus_ATCC_1997 AGGMGLLLTQWATYRGVRVITTVSSEAKEKLSREAGAAEVLPYPDPAD--
MLBr_00118|M.leprae_Br4923 TSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDE----
:.*:* * * .. * *..: * . . ** .: *
Mb1489c|M.bovis_AF2122/97 AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASG
Rv1454c|M.tuberculosis_H37Rv AWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAASG
MMAR_2259|M.marinum_M AWQFGGQVRALTDGAGVAAVYDGVGATTFDASLASLAVRGTLALFGAASG
MUL_1855|M.ulcerans_Agy99 AWQFGGQVRALTDGAGVAAVYDGVGATTFDASLASLAVRGTLALFGAASG
MAV_3325|M.avium_104 ADEFGNRIRALTDGAGVAAVYDGVGASTFDASLASLAVRGTLALFGAASG
Mvan_2724|M.vanbaalenii_PYR-1 PKAFGDRIRELTDGDGVAAVFDGVGASTFEASLASLAVRGTLALFGAASG
Mflv_3686|M.gilvum_PYR-GCK AAAFGDRIRELTDGDGVAAVYDGVGASTFEASLASLAIRGTLALFGAASG
TH_3440|M.thermoresistible__bu PEEFGARIRDLTGGEGVPVVYDGVGRSTFDASLASLAVRGTLALFGAASG
MSMEG_3106|M.smegmatis_MC2_155 PQPFASRVRELTGGAGVAAVYDGVGATTFDASLASLAVRGTLALFGASSG
MAB_2757|M.abscessus_ATCC_1997 PSEFAAQIRELTAGEGVAVVYDGVGKSTFEASLAAVRVRGLIALYGAASG
MLBr_00118|M.leprae_Br4923 --DFVARLQQQNGG--ADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGG
* ::: . * . .: * :* : :: .: :: : * : : * .*
Mb1489c|M.bovis_AF2122/97 PVPPVDP-----QRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIG
Rv1454c|M.tuberculosis_H37Rv PVPPVDP-----QRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIG
MMAR_2259|M.marinum_M PVPPVDP-----QRLNAAGSVYLTRPSLFHFIRTAEEFSWRASELFDAIS
MUL_1855|M.ulcerans_Agy99 PVPPVEP-----QRLNAAGSVYLTRPSLFHFIRTAEEFSWRASELFDAIS
MAV_3325|M.avium_104 PVPPFDP-----QRLNAAGSVFLTRPSLAHFIRTGQEFSWRAEELFAAIA
Mvan_2724|M.vanbaalenii_PYR-1 PVPPVDP-----QRLNAAGSVYLTRPNLAHYTRTPDEFSWRAGELLTAIA
Mflv_3686|M.gilvum_PYR-GCK PVPPIDP-----QRLNTAGSVFLTRPNLAHHTRTPDEFSWRAGELLTAIA
TH_3440|M.thermoresistible__bu PVPPFDP-----QRLNAAGSVYLTRPSLVHFTRTPDEFGWRAGEFLSAVA
MSMEG_3106|M.smegmatis_MC2_155 PVPPFDP-----QRLNAAGSVFLTRPTLAHHTRTADEFSWRAGELINAIA
MAB_2757|M.abscessus_ATCC_1997 QVPPFDP-----QRLTAK-SAVLTRPTMGHFIRTPEEFAWRADDVLDLVS
MLBr_00118|M.leprae_Br4923 VKGELNLGKVLSKRARIIGSTLRARPVNGPNSKS-EIVAAVTASIWPMIA
.: :* *. :** :: : .. : .. :.
Mb1489c|M.bovis_AF2122/97 SEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP-------------
Rv1454c|M.tuberculosis_H37Rv SEAITVAVGGRYPLADALRAHQDLEARKTVGSVVLLP-------------
MMAR_2259|M.marinum_M SGVITIEVGGRYRLADAMKAHQDLEARKTIGSVVLLP-------------
MUL_1855|M.ulcerans_Agy99 SGVITIEVGGRYRLADAMKAHQDLEARKTIGSAVLLP-------------
MAV_3325|M.avium_104 AGDITVEVGGRYPLADAARAHRDLQGRKTTGSIVLLP-------------
Mvan_2724|M.vanbaalenii_PYR-1 DGTLDVTVSHRYALRDAEQAHRDLQGRKTVGSVVLLP-------------
Mflv_3686|M.gilvum_PYR-GCK DGALTVTVSNRYALREAEQAHRDLQGRRTVGSVVLIP-------------
TH_3440|M.thermoresistible__bu DGTLTITVGERYPLAEAERAHRDLEGRKTVGSVVLLP-------------
MSMEG_3106|M.smegmatis_MC2_155 DGSIKITVGGTYPLAEASRAHTDLQGRKTVGSIVLIP-------------
MAB_2757|M.abscessus_ATCC_1997 RGTLKITIGAGYPLEQAAQAHTDLEARKTTGSVVLVP-------------
MLBr_00118|M.leprae_Br4923 DGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
: :. : :* ** * . :. *. **