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AQVVVYDEFGEADVLRIIDEPVGRPGAAEIVVRIEAFGINRLDQMMRAGQYPAPIRLPHARLGVEGAGFV HAVGSAVEGLSVGDRVIITAVPDADIRGTYAEYVTVPAQRVIGWPDGVDLVGAAALWVSYSTAYGALIEK ARIRPGDHVLITAASSGVGLAAIQVANQIGAIPLAVTRSPDKKSALLNAGAAAVFTSDVEDVASAAKSYT GGLGVDVIVDSVMGPGLAQLAGAAKAGGTLVTVGWLDPRPASFPMGQLTIYPYASFEHTLDPAAVQRIAA FLRAGLRSGALQPTVDRVFSFADIAEAHRYLEKGQHIGKIVVTHSHDR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4067 | - | - | 100% (329) | zinc-containing alcohol dehydrogenase superfamily protein |
M. smegmatis MC2 155 | MSMEG_0408 | - | 3e-31 | 31.50% (327) | type I modular polyketide synthase |
M. smegmatis MC2 155 | MSMEG_4146 | - | 7e-31 | 31.42% (331) | quinone oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2958 | ppsC | 2e-34 | 31.31% (329) | phenolpthiocerol synthesis type-I polyketide synthase PPSC |
M. gilvum PYR-GCK | Mflv_2449 | - | 3e-34 | 33.44% (320) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv2933 | ppsC | 2e-34 | 31.31% (329) | phenolpthiocerol synthesis type-I polyketide synthase PPSC |
M. leprae Br4923 | MLBr_02355 | - | 1e-31 | 30.25% (324) | polyketide synthase |
M. abscessus ATCC 19977 | MAB_3622c | - | 4e-34 | 32.62% (328) | putative quinone oxidoreductase |
M. marinum M | MMAR_1774 | ppsC | 8e-32 | 29.79% (329) | phenolpthiocerol synthesis type-I polyketide synthase PpsC |
M. avium 104 | MAV_1763 | - | 1e-31 | 32.93% (328) | tylactone synthase modules 4 & 5 |
M. thermoresistible (build 8) | TH_3440 | - | 3e-31 | 31.69% (325) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
M. ulcerans Agy99 | MUL_2017 | ppsC | 2e-31 | 29.48% (329) | phenolpthiocerol synthesis type-I polyketide synthase PpsC |
M. vanbaalenii PYR-1 | Mvan_4202 | - | 8e-32 | 31.48% (324) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 MSTVEGLRDPASSFAIVGYAARFPGAADADEFWRVLAEGRDAVSEVPKDR Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 WDADEFFDPDPDAPGKVVTRRAGFVDDVTGFDAPFFGMSAREARLLDPQH Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 RLLLETAWRAVEHSGTAPTDLANTNTGVFIGISTHDYLGMASDELTYDQI Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 EAYTAIGTSSAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 GECDLALAGGANVLLTPATMITFSQAHMLAPDGRCKTFDAAADGYVRGEG Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 CGVLVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 EALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAGREASRPLLI Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 GSVKTNIGHLEAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 VQVVKEATAWQRNGRPRVAGVSSFGFAGTNAHVILEEAPDGTGRAAVPPA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 AVRPPGQRRFHVLPLSARTPAALVQIAGEYRDWLSAHPDTALADLCLTAG Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 AGRAHFEHRAALVVDSTGSAGELLAALADDRPAPGLLRGVCEDAPKTAWL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 FTGQGSQYAGMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTDD Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 PASEATLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAAC Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 VAGVLRVEDGARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFPSL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 SVAAYNGANTVLSGPGQELEQAVARLTAEKVRCDWLDTSHAFHSALLDPI Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 LDEFESYANQFDFGPPQRILICNRTGSALGRSVKLDGAYWRRHARQPVEF Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 AKSVHTLADLGCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRRNTA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 DHRQITEALAEAYIVGHLPDFGAAVGPARKLDLPTYPFQHRQYWFSEQRV Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 PPGSQQTSTQTTAVRLLEDGRIAELAELLDGASADQHTLDVLTKLAAQHN Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 QQRKSRSIAEDRYEIRWEKSTVPGPEAEATWLVVGDDDDAVAPLVDALTA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 RGHQHRILVLPASDADEERLEIVLRAAAAEEAPLRIALVAALDSGTAPSM Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 RSLLRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQRVTDADTVFPDQ Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 SCLWGFGRAASLEYPQLWGGLADLAQGSAEEWSRLVRVASAPRDPAVGED Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 QIALRGSDIYVPRLTRRSGQPAAAALTLRADATYLVTGGLGSIGLEIAGH Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 LAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRVIAADVADAHHVA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 RLLGAVRAELPPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 SEAAADLRLDFFVSTSSIASVWGGLGQTAYGAANAFLDGLAWRLREQGVN Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 GISVNFGPWAAGMADENARARLAQRGIKTLSPADALAGLADVMATAAAQG Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------M Rv2933|M.tuberculosis_H37Rv -------------------------------------------------M MLBr_02355|M.leprae_Br4923 -------------------------------------------------M MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 VVARIDWTRFLPLYQQAGQRSLLAELAREIPDFAPAPTPSGKTGLVERLA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 TAATPDRRAIITEALHKIDDLTARLEIAEK-------------------- Rv2933|M.tuberculosis_H37Rv TAATPDRRAIITEALHKIDDLTARLEIAEK-------------------- MLBr_02355|M.leprae_Br4923 TASTPDRRAIITEALHKIDDLTARLEIAEK-------------------- MMAR_1774|M.marinum_M MTATPDRRAVITDALRKIDDLSARLEIAEK-------------------- MUL_2017|M.ulcerans_Agy99 MTATPDRRAVITDALRKIDDLSARLEIAEK-------------------- MAV_1763|M.avium_104 GAPVQQRRKLMTEFLRNAVAEVTRVDAAEIREDAGFFDLGMDSLMAIELR Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -------------------------------------------------- Rv2933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02355|M.leprae_Br4923 -------------------------------------------------- MMAR_1774|M.marinum_M -------------------------------------------------- MUL_2017|M.ulcerans_Agy99 -------------------------------------------------- MAV_1763|M.avium_104 RHIEQGVGKQIPATLAMDYPRLSDVAEYLLGDVLDLRGQPDAKPAPPAGT Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 -----SSSEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWD Rv2933|M.tuberculosis_H37Rv -----SSSEPIAVIGMGCRFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWD MLBr_02355|M.leprae_Br4923 -----SSTEPIAVIGMGCRFPGGVNNPEQFWDLLCDGRSGIVRVPSDRWD MMAR_1774|M.marinum_M -----AGTEPIAVVGMGCRFPGGVDNPEQFWDLLHEGRSGIVRVPSQRWD MUL_2017|M.ulcerans_Agy99 -----AGTEPIAVVGMGCRFPGGVDNPEQFWDLLHEGRSGIVRVPSQRWD MAV_1763|M.avium_104 PAPAGRTDEPIAIVAMACRFPG-AADPEAFWELLSGGVDAIREVPEDRFD Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 ADAYYCDDHTVPGTICSTEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQ Rv2933|M.tuberculosis_H37Rv ADAYYCDDHTVPGTICSTEGGFLTSWQPDEFDAEFFSISPREAAAMDPQQ MLBr_02355|M.leprae_Br4923 ADAYYTDDHTVPGTICSTEGGFLTGWQPDEFDAEFFSISPREASAMDPQQ MMAR_1774|M.marinum_M ADALYTDDHTLAGTICNREGGFLSTWEPSEFDAEFFSIPPREAAAMDPQQ MUL_2017|M.ulcerans_Agy99 ADALYTDDHTLAGTICNREGGFLSTWEPSEFDAEFFSIPPREAAAMDPQQ MAV_1763|M.avium_104 IDEFYDPDPETPGKMYSRFGGYLD--QIDEFDPEFFGISPREAVWIDPQQ Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 RLLIEVAWEALEDAGVPQHTIRGTQTSVFVGVTAYDYMLTLAGRLRPVDL Rv2933|M.tuberculosis_H37Rv RLLIEVAWEALEDAGVPQHTIRGTQTSVFVGVTAYDYMLTLAGRLRPVDL MLBr_02355|M.leprae_Br4923 RLLIEVAWEALEDAGVAPHTIRGTQTSVFVGVTAYDYMLTLAGRLRPEDL MMAR_1774|M.marinum_M RLFLEVAWEALENAGIPPQTIRGTQTGVFVGVTAYDYMLMMSGAVRAEEL MUL_2017|M.ulcerans_Agy99 RLFLEVAWEALENAGISPQTIRGTQTGVFVGVTAYDYMLMMSGAVRAEEL MAV_1763|M.avium_104 RLVLETVWEGLERAGYSPAALRGSRSGIFVGVGANEYSHLLS-AESVDKI Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 DAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSSLVAVHLACQSLRG Rv2933|M.tuberculosis_H37Rv DAYIPTGNSANFAAGRLAYILGARGPAVVIDTACSSSLVAVHLACQSLRG MLBr_02355|M.leprae_Br4923 DAYIPTGNSANFAAGRLAYILGVRGPAVVIDTACSSSLVAVHLACQSLRH MMAR_1774|M.marinum_M DAYLLTGNSANFAAGRTAYLLGARGPAMVLDTACSSSLVAIHLACQSLRW MUL_2017|M.ulcerans_Agy99 DAYLLTGNSANFAAGRTAYLLGARGPAMVLDTACSSSLVAIHLACQSLRW MAV_1763|M.avium_104 EPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQACQALHS Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 RESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVRGEG Rv2933|M.tuberculosis_H37Rv RESDMALVGGTNLLLSPGPSIACSRWGMLSPEGRCKTFDASADGYVRGEG MLBr_02355|M.leprae_Br4923 RESDAALVGGTNLLLSPGPSIACSRWGMLSPAGQCKAFDVSADGYVRGEG MMAR_1774|M.marinum_M RETDMALVGGTNLLLSPGTSIACSRWGMLSPEGQCKTFDADADGYVRSEG MUL_2017|M.ulcerans_Agy99 RETDMALVGGTNLLLSPGTSIACSRWGMLSPEGQCKTFDADADGYVRSEG MAV_1763|M.avium_104 GDCDLALAGGVNVLLSPVSNIAASRARMLSPVGRCKTFDATADGYVRSEG Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 AAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLA Rv2933|M.tuberculosis_H37Rv AAVVVLKRLDDAVRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLA MLBr_02355|M.leprae_Br4923 AGVVVLKRLDDAVRDGNRILAIVRGSAVNQDGASSGVTVPNGPAQQELLR MMAR_1774|M.marinum_M AGVVVLKRLSDAQRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLA MUL_2017|M.ulcerans_Agy99 AGVVVLKRLSDAQRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLA MAV_1763|M.avium_104 CGILVLKRMSDAVRDGDRVCAVIPASAVNQDGASSGLTVPNGGAQQRLIA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 KALTSSKLTAADIDYVEAHGTGTPLGDPIELDSLSKVFSDR---AGSDQL Rv2933|M.tuberculosis_H37Rv KALTSSKLTAADIDYVEAHGTGTPLGDPIELDSLSKVFSDR---AGSDQL MLBr_02355|M.leprae_Br4923 TALASSKLTAADIDYIEAHGTGTPLGDPIELDSLSKVFSDRQSRRGSVPL MMAR_1774|M.marinum_M QALDSAKLTPADIDYIEAHGTGTPLGDPIELDSLSKVFADR---EGREPL MUL_2017|M.ulcerans_Agy99 QALDSAKLTPADIDYIEAHGTGTPLGDPIELDSLSKVFADR---EGREPL MAV_1763|M.avium_104 TALSRAGLSGDDVDYLEAHGTGTALGDPIEVQAAGAVYGATR--DTDRPL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 VIGSVKTNLGHLEAAAGVAGLMKAVLAVHNGYIPRHLNFHQLTPHASEAA Rv2933|M.tuberculosis_H37Rv VIGSVKTNLGHLEAAAGVAGLMKAVLAVHNGYIPRHLNFHQLTPHASEAA MLBr_02355|M.leprae_Br4923 VIGSVKTNLGHLEAAAGIAGFIKAVLAVQRGFIPRHLNFHQLTTHASEAA MMAR_1774|M.marinum_M VLGAVKTNLGHLEAAAGIAGFMKSVLAVGHGRIPRNLNFRQLTPHASEGV MUL_2017|M.ulcerans_Agy99 VLGAVKTNLGHLEAAAGIAGFMKSVLAVGHGRIPRNLNFRQLTPHASEGV MAV_1763|M.avium_104 LIGSVKTNIGHLEAASGVAGLIKVVLSLQHEMLPQSLHFETPSPHIPWDS Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 SRLRIAADGIDWPTTGRPRRAGVSSFGVSGTNAHVVIEQAPDPMAAAGTE Rv2933|M.tuberculosis_H37Rv SRLRIAADGIDWPTTGRPRRAGVSSFGVSGTNAHVVIEQAPDPMAAAGTE MLBr_02355|M.leprae_Br4923 SRLNIASEGLEWPTVGRPRRAGVSSFGVSGTNAHVVLEQAPDPVAVPAPG MMAR_1774|M.marinum_M SRLTIATEEMEWPATDQPRRAGVSSFGVSGTNAHVVIEQAPDPAPVP--- MUL_2017|M.ulcerans_Agy99 SRLTIATEEMEWPATDQPRRAGVSSFGVSGTNAHVVIEQAPDPAPVP--- MAV_1763|M.avium_104 LPLRVVDKAVPWQTNGRPRRAGVSSFGFTGTNAHVLIEEAPQPVTTQDAT Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 PQRGPVP-AVSTLVVFGKTAPRVAATASVLADWLDGPGAAVPLADVAHTL Rv2933|M.tuberculosis_H37Rv PQRGPVP-AVSTLVVFGKTAPRVAATASVLADWLDGPGAAVPLADVAHTL MLBr_02355|M.leprae_Br4923 PALRLVP-AVSTLVVSGKTVQRVAATASVLADWMEGPGAAVPLTDVAHTL MMAR_1774|M.marinum_M --RDAAP-AVSTLVVSGKTAQRVAATAAALADWMEGPGSEVPLSDVAHTL MUL_2017|M.ulcerans_Agy99 --RDAAP-AVSTLVVSGKTAQRVAATAAALADWMEGPGSEVPLSDVAHTL MAV_1763|M.avium_104 PAAESDARPVDVLPLSARSPEALLALAQRYGEWLHAHP-DADIGDLCFTV Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 NHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGTV Rv2933|M.tuberculosis_H37Rv NHHRARQTRFGTVAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGTV MLBr_02355|M.leprae_Br4923 NHHRARHTKFGTVAAVDRGQAVAGLRALAAGQSTSGVVAPRDSVVGPGTV MMAR_1774|M.marinum_M NHHRARQPKFATVAAVDREQAITGLRALAAGEPATGVVGCPEKPLGPGTV MUL_2017|M.ulcerans_Agy99 NHHRARQPKFATVAAVDREQAITGLRALAAGEPATGVVGCPEKPLGPGTV MAV_1763|M.avium_104 GAGRAHFEHRAALVVDSVRSAREALADLADNRTRPGVARG-ECTDPPTTA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 FVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAG- Rv2933|M.tuberculosis_H37Rv FVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAG- MLBr_02355|M.leprae_Br4923 FVYSGRGSQWAGMGRQLMADEPAFAEAIAKLEHEFVVQAGFSLHEVIAN- MMAR_1774|M.marinum_M FVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPVFLAEAGFSLHDVIAD- MUL_2017|M.ulcerans_Agy99 FVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPVFLAEAGFSLHDVIAD- MAV_1763|M.avium_104 WLFTGQGSQYPGMARELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFAT Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 --------GKELVGIEQIQLGLIGMQLALTALWRSYGVTPDAVIGHSMGE Rv2933|M.tuberculosis_H37Rv --------GKELVGIEQIQLGLIGMQLALTALWRSYGVTPDAVIGHSMGE MLBr_02355|M.leprae_Br4923 --------GKELVGIEQIQLGLMGMQLALTELWRSYGVEPDAVIGHSMGE MMAR_1774|M.marinum_M --------GKELEGIEQIQLGLIGMQLALTALWRHYGVTPDLVIGHSMGE MUL_2017|M.ulcerans_Agy99 --------GKELEGIEQIQLGLIGMQLALTALWRHYGVTPDLVIGHSMGE MAV_1763|M.avium_104 DKDTGGEAGKTLRNTAFAQPALFAVEMGLARLWQSWGVEPDVVLGHSVGQ Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 VAAAVVAGALTPAQGLRVTAVRSRLMAPLSGQGTMALLELDAEATEALIA Rv2933|M.tuberculosis_H37Rv VAAAVVAGALTPAQGLRVTAVRSRLMAPLSGQGTMALLELDAEATEALIA MLBr_02355|M.leprae_Br4923 VAAAVVAGALTPTQGLRVTATRSRLMAPLSGQGTMALLELDAVATEALIA MMAR_1774|M.marinum_M VAATVVAGALTPAEGLRVTATRSRLMAPLSGQGTMAMLELDATATEALIA MUL_2017|M.ulcerans_Agy99 VAAAVVAGALTPAEGLRVTATRSRLMAPLSGQGTMAMLELDATATEALIA MAV_1763|M.avium_104 YAAACVAGVFSLEDGARLMAERGRLFGGLPDGGRMVAVFADAQYVEELAN Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 DYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGFATRVNIEVAPHN Rv2933|M.tuberculosis_H37Rv DYPEVSLGIYASPRQTVISGPPLLIDELIDKVRQQNGFATRVNIEVAPHN MLBr_02355|M.leprae_Br4923 DYPQVSLGIYASPRQTVIAGPTAMIDALIDKVRQQDGFATRVNIEVAPHN MMAR_1774|M.marinum_M GYPEVTLAIYASPRQTVIAGPPQMIDELIEQVRAQNRFAGRVNIEVAPHN MUL_2017|M.ulcerans_Agy99 GYPEVTLAIYASPRQTVIAGPPQMIDELIEQVRAQNRFAGRVNIEVAPHN MAV_1763|M.avium_104 DCPRVSVAAYNGP-NTVLSGPGADLEQIVARGASDGIRCSWLETSHAFHS Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 PAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEHWA Rv2933|M.tuberculosis_H37Rv PAMDALQPAMRSELADLTPQPPTIPIISTTYADLGISLGSGPRFDAEHWA MLBr_02355|M.leprae_Br4923 PAMDALQPQMRSELADLTPQQPTIPIISTTYEDF----GSTPVFDVEHWA MMAR_1774|M.marinum_M PAMDALQPLMRSELADLTPRPPSIPIISTTYEDLE----SRPAFDAEHWA MUL_2017|M.ulcerans_Agy99 PAMDALQPLMRSELADLTPRPPSTPIISTTYEDLE----SRPAFDAEHWA MAV_1763|M.avium_104 ELLDPVLDEFESYAAHLDFAVPTLPLVCNRTGTVLT---TETPLDARYWR Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 TNMRNPVRFHQAIAHA----GADHHTFIEISAHPLLTHSISDTLR---AS Rv2933|M.tuberculosis_H37Rv TNMRNPVRFHQAIAHA----GADHHTFIEISAHPLLTHSISDTLR---AS MLBr_02355|M.leprae_Br4923 TNMRNPVRFQQAITHASSGVGGDYHTFIEISAHPLLTHSISDILCS-IAG MMAR_1774|M.marinum_M TNMRNPVRFQQAITHAFNGADTAHHTFIEISAHPLLTHAISETLAASQDS MUL_2017|M.ulcerans_Agy99 TNMRNPVRFQQAITHAFNGADTAHHTFIEISAHPLLTHAISETLAANQDS MAV_1763|M.avium_104 RHSRQPVQFAESVRTVA---ALGCTVLMEIGPQPVLTGAAVQVWPEHLAA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 YDVDN-----YLSIGTLQRDAHDTLEFHTNLNTTHTTHPPQTPHPPEPHP Rv2933|M.tuberculosis_H37Rv YDVDN-----YLSIGTLQRDAHDTLEFHTNLNTTHTTHPPQTPHPPEPHP MLBr_02355|M.leprae_Br4923 TAEENAVGAGYLSIGTLQRDAHDTLEFHTNLNATHTSRPPRTPHPPEPHP MMAR_1774|M.marinum_M AQGETDSGASYLSIGTLQRDAHDTLTFHTNFNATHTTRGPQTPHPAEPHP MUL_2017|M.ulcerans_Agy99 AQGETDSGASYLSIGTLQRDAHDTLTFHTNFNATHTTHGPQTPHPAEPHP MAV_1763|M.avium_104 PRAIVS------LRKGVGDRRQIAEGLAAAYVSGHRPEFAALHRRPRRKL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 VLPTTPWQHTQHWITATSAAYHRPDTHPLLGVG--VTDPTNGTRVWESEL Rv2933|M.tuberculosis_H37Rv VLPTTPWQHTQHWITATSAAYHRPDTHPLLGVG--VTDPTNGTRVWESEL MLBr_02355|M.leprae_Br4923 VLPITPWQHTRHWISAMSAAYHRADTHPLLGVG--VTDPTSGTRVWESQL MMAR_1774|M.marinum_M VLPTTPWQHGQHWISSTTASRYATGSHPLLGIG--VTDPTNGTRVWESQL MUL_2017|M.ulcerans_Agy99 VLPTTPWQHGQHWISSTTASRYATGSHPLLGIG--VTDPTNGTRVWESQL MAV_1763|M.avium_104 ELPTYPFQRRRFWPKASGIAGIDGQGAAASGLLGSAKELASGDSVYTSRL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 DP-DLLWLADHVIDDLVVLPGAAYAEIALAAATDTFA------------- Rv2933|M.tuberculosis_H37Rv DP-DLLWLADHVIDDLVVLPGAAYAEIALAAATDTFA------------- MLBr_02355|M.leprae_Br4923 GP-DLLWLGDHVIDDLCVLPGAAYAEVALAAATDTFPNER---------- MMAR_1774|M.marinum_M GP-DLLWLSDHVIDDLCVLPGSAYAEVALAAAMDTFKDAEGDQGSADPAG MUL_2017|M.ulcerans_Agy99 GP-DLLWLGDHVIDDLCVLPGSAYAEVALAAAMDTFKDAEGDQGSADPAG MAV_1763|M.avium_104 SVKSQPWLADHVIYGTVVVPGATYAAMALAAVGPPAR------------- Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 ------VEQDQPWMISELDLRQMLHVTPGTVLVTTLTGDEQRCQVEIRTR Rv2933|M.tuberculosis_H37Rv ------VEQDQPWMISELDLRQMLHVTPGTVLVTTLTGDEQRCQVEIRTR MLBr_02355|M.leprae_Br4923 ------VEGDQPWMIYELDLHQVLHVTEGTVLVTTLTGDQQRCRIEMRTR MMAR_1774|M.marinum_M PDGSVASNAHQPWVIRELSLHQLLHVTDGTKLVTTLTGDEHTCRIEISTQ MUL_2017|M.ulcerans_Agy99 PDGSVASNAHQPWVIRELSLHQLLHVTDGTKLVTTLTGDEHTCRIEISTQ MAV_1763|M.avium_104 ---------VQNVYFYEPIILPDKASREVQLSLHPLQEGGWSFRVDSRPY Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 SGSSGWTTHATATVARAEPLAPLDHEGQRREVTTADLEDQLDPDDLYQRL Rv2933|M.tuberculosis_H37Rv SGSSGWTTHATATVARAEPLAPLDHEGQRREVTTADLEDQLDPDDLYQRL MLBr_02355|M.leprae_Br4923 NGFSGWTTHATATVGPAESVQPSDRE--ERTATPVDVVDELGPEDLYQRL MMAR_1774|M.marinum_M SGASGWVKHASATLARHDASDSDAPR--PAVEEAGAPTDELDPEQLYQRL MUL_2017|M.ulcerans_Agy99 SGASGWVKHASATLARHDASDSDAPR--PAVEKAGAPTDELDPEQLYQRL MAV_1763|M.avium_104 GVPDAEWSLNADGTVVAGIEDEPAADPADHIDAVIERLDRNRPQLLFDSF Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 RGAGQQHGPAFQGIVGLAVTQAGVARAQVRLPASARTGSREFMLHPVMMD Rv2933|M.tuberculosis_H37Rv RGAGQQHGPAFQGIVGLAVTQAGVARAQVRLPASARTGSREFMLHPVMMD MLBr_02355|M.leprae_Br4923 CSAGQQHGPAFQGIVGLAVEESGAARAEVRLPSSARMGFRDFLLHPVMMD MMAR_1774|M.marinum_M RGAGQQHGPAFRGIVGLAVTESGAARADVRLPSSARIGYRGFALHPVMMD MUL_2017|M.ulcerans_Agy99 RGAGQQHGPAFRGIVGLAVTGSGAARADVRLPSSARIGYRGFALHPVMMD MAV_1763|M.avium_104 AESELEWGTTWSTSLKSLWMGDGEAVGDVTVGDELAEHLGTEPMHPVLLD Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 IALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGVHVYGDITRGV Rv2933|M.tuberculosis_H37Rv IALQTLGATRTATDLAGGQDARQGPSSNSALVVPVRFAGVHVYGDITRGV MLBr_02355|M.leprae_Br4923 IALQTLGATRMATDLAGG------PTARKTLVLPVRFAGVHVYGDVTRGV MMAR_1774|M.marinum_M IAVQTLGATRMALELAEQ------QDSGHTLVLPIRFAGIHVYGDIAEGV MUL_2017|M.ulcerans_Agy99 IAVQTLGATRMALELTEQ------QDSGHTLVLPIRFAGIHVYGDIAEGV MAV_1763|M.avium_104 LCTGVVFPAFPALLAAEQG--------FNDLLLPLRYGQVSLREKMPRRF Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 RAVGSLAAAG---DRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGAT-- Rv2933|M.tuberculosis_H37Rv RAVGSLAAAG---DRLVGEVVLTDANGQPLLVVDEVEMAVLGSGSGAT-- MLBr_02355|M.leprae_Br4923 CAVGLLTATEGL-DRLVGEVVLTDLDGQPLLVIDEVQMTVLGAGSDAT-- MMAR_1774|M.marinum_M RAIGSLAATDRP-DRLVGRVTLVDPDGQPLLVIDEVEMAVLGSSASPT-- MUL_2017|M.ulcerans_Agy99 RAIGSLAATDRP-DRLVGRVTLVDPDGQPLLVIDEVEMAVLGSSASPT-- MAV_1763|M.avium_104 YCRGKWRPSALDSETQVFDIDFIDRDGRHLGGIREFTVKRAPREALLRGL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 --ELTNRLFMLEWEPAPLEKTA---EATGALLLIGDPAAGDPLLPALQSS Rv2933|M.tuberculosis_H37Rv --ELTNRLFMLEWEPAPLEKTA---EATGALLLIGDPAAGDPLLPALQSS MLBr_02355|M.leprae_Br4923 --ELTDRLFTLEWEPTPLYKEVSRSSAQGGLLLIGDVAAGDPLLLALQSS MMAR_1774|M.marinum_M --ELTSRLFTLEWEPKPLDQTA---ATPGAVLLIGDLGADDRLLPALQTS MUL_2017|M.ulcerans_Agy99 --ELTSRLFTLEWEPKPLDQTA---ATPGAVLLIGDLGADDRLLPALQTS MAV_1763|M.avium_104 GGDATRLLYTLGWHEVPPQPSNDGVANPSGTWLIAGFDELGAQLPGCIPF Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 LRDRITD-----LELASAADEATLRAAISRT--SWDGIVVVCPPRANDES Rv2933|M.tuberculosis_H37Rv LRDRITD-----LELASAADEATLRAAISRT--SWDGIVVVCPPRANDES MLBr_02355|M.leprae_Br4923 LRARLSENGPPPVDCVSFSDEVKLQAAITRTDISWDGIVVVCPPRASDES MMAR_1774|M.marinum_M LTGSVAE-----LDVVSPADAAKLRAAITRTDARWQDIVVVCPPRAVDEA MUL_2017|M.ulcerans_Agy99 LTGSAAE-----LDVVSPADAAKLRAAITRTDARWQDIVVVCPPRAVDEA MAV_1763|M.avium_104 DRNTDPE-----------SFGQLLARAEDRGGPVTGIVWRATQSGGRESS Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 MPDEAQLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGES Rv2933|M.tuberculosis_H37Rv MPDEAQLELARTRTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGES MLBr_02355|M.leprae_Br4923 LPDDAQLELAQTRTLQIAGVVQAVTQMGARKSPRLWIVTRGAQQLNAGES MMAR_1774|M.marinum_M LPQDAQLDLTQQRTLMIADVAQTVTRMGARNSPRLWIVTRGAQQLSPADE MUL_2017|M.ulcerans_Agy99 LPQDAQLDLTQQRTLMIADVAQTVTRMGARNSPRLWIVTRGAQQLSPADE MAV_1763|M.avium_104 AESVARLETEIAGLLTAVHALQNADGSAVKLPGGLWIVTERGVATESGEP Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 VTLAQTGLRGIARVLTFEHSELNTTLVDIEPDGTGSLAALAEELLAGSEA Rv2933|M.tuberculosis_H37Rv VTLAQTGLRGIARVLTFEHSELNTTLVDIEPDGTGSLAALAEELLAGSEA MLBr_02355|M.leprae_Br4923 VTLAQTELRGIVRVLTFEHSELKATLLDIEADGTDSLDDLTEELLAGSNH MMAR_1774|M.marinum_M VTLAQTQLRGIARVLTFEHPELKTTLVDIEGDGEGSLTALTQELLAGADD MUL_2017|M.ulcerans_Agy99 VTLAQTQLRGIARVLIFEHPELKTTLVDIEGDGEGSLAALTQELLAGADD MAV_1763|M.avium_104 VDPVQAALWGLGRTIVNEEPALRCRLVDSDGS-EQAVRSLAGLLGAPLDE Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu ------------------------------------------------VQ MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 DEVALRDGQRYVNRLVPAPTTTSGDLAAEARHQVVNLDSSGASRAAVRLQ Rv2933|M.tuberculosis_H37Rv DEVALRDGQRYVNRLVPAPTTTSGDLAAEARHQVVNLDSSGASRAAVRLQ MLBr_02355|M.leprae_Br4923 DEVAYRDGQRYVNRLVPAPITPKGELAGETRRKVVELGGLG----AVQLQ MMAR_1774|M.marinum_M DEISLRDGQRFVHRLVAAPTVGTGDLELESRRTVVNLDAGG----AVQLR MUL_2017|M.ulcerans_Agy99 DEISLRDGQRFVHRLVAAPTVGTGDLELESRRTVVNLDAGG----AVQLR MAV_1763|M.avium_104 PELAVRQGKLLASRLLPWARSGHLAVPRGT---------------DYVLA Mflv_2449|M.gilvum_PYR-GCK ---------------------------------------------MRAAM Mvan_4202|M.vanbaalenii_PYR-1 ---------------------------------------------MRAAV MAB_3622c|M.abscessus_ATCC_199 --------------------------------------------MAYAVR TH_3440|M.thermoresistible__bu TAAAQRRDEIGVIGVALRAVRTTGQNDPRMEHIRAGELHTGMIGAMKAIE MSMEG_4067|M.smegmatis_MC2_155 --------------------------------------------MAQVVV Mb2958|M.bovis_AF2122/97 IDQPGRLDALNVHEVKRGRPQGDQVEVRVVAAGLNFSDVLKAMGVYPGLD Rv2933|M.tuberculosis_H37Rv IDQPGRLDALNVHEVKRGRPQGDQVEVRVVAAGLNFSDVLKAMGVYPGLD MLBr_02355|M.leprae_Br4923 IDQPGRLDALTVHQVKRGEPEGDQVEVRVVAAGLNFSDVLKAMGVYPGLD MMAR_1774|M.marinum_M TDQPGRLDSLTVHQVKRCRPQGDQVEVRVAAAGLNFSDVLKAMGVYPGLD MUL_2017|M.ulcerans_Agy99 TDQPGRLDSLTVHQVKRCRPQGDQVEVRVAAAGLNFSDVLKAMGVYPGLD MAV_1763|M.avium_104 PTERGAIDNLRLIEQEAPPPAEGCVQVRVEAGGLNFREVLNVLGLYP--- Mflv_2449|M.gilvum_PYR-GCK CREYGPPEVVRVEDVAEPVAGPGQIGVRVDAAAVNFPDVLLVAGTYQISV Mvan_4202|M.vanbaalenii_PYR-1 CPQYGPPEVVRVEERPEPSAGPGQVVVRVEAAAVNFPDVLLVADSYQVSV MAB_3622c|M.abscessus_ATCC_199 IHETGGPEVLRGENVQVGAPGPGEVRIRHHAVGLNFADVYFRTGVYPVAL TH_3440|M.thermoresistible__bu VRETGGPEVLTYVDVPEPTPGPGQVLIKAEAIGVNFIDTYFRSGLYPREV MSMEG_4067|M.smegmatis_MC2_155 YDEFGEADVLRIIDEPVGRPGAAEIVVRIEAFGINRLDQMMRAGQYPAPI : * : : : . : :: * .:* : . * Mb2958|M.bovis_AF2122/97 GAAPVIGG-ECVGYVTAIGDEVDGVEVGQRVIAFGPGT------FGTHLG Rv2933|M.tuberculosis_H37Rv GAAPVIGG-ECVGYVTAIGDEVDGVEVGQRVIAFGPGT------FGTHLG MLBr_02355|M.leprae_Br4923 GGAPAIGG-ECVGYVTAIGDDVDSVEVGQRVIAFGPGT------FGTYVG MMAR_1774|M.marinum_M GAAPVIGG-ECVGYVTAIGDDVDSLEIGQRVIAFGPGT------FGSHLG MUL_2017|M.ulcerans_Agy99 GAAPVIGG-ECVGYVTAIGDDVDSLEIGQRVIAFGPGT------FGSHLG MAV_1763|M.avium_104 GDPGPLGG-DFAGTVTQLGSGVTGLEVGTRVYGFMQGA------FASRFN Mflv_2449|M.gilvum_PYR-GCK PP-PFVPGSEFAGVVDEIGPGTEGFTIGDRVSGTAMFG-----AFAERTV Mvan_4202|M.vanbaalenii_PYR-1 AP-PFVPGSEFTGVVDEIGPHTTGFTVGERVAGTGMFG-----AFAERVV MAB_3622c|M.abscessus_ATCC_199 P---AGMGVAGSGIIEAVGPGVSQFGPGDRVTYTGSPLG----AYSTERV TH_3440|M.thermoresistible__bu P---FIVGTEVCGTVEAVGDGVAALRVGDRV-LTDKANG----AYAEYTV MSMEG_4067|M.smegmatis_MC2_155 RLPHARLGVEGAGFVHAVGSAVEGLSVGDRVIITAVPDADIRGTYAEYVT * * : :* . . * ** :. Mb2958|M.bovis_AF2122/97 TIADLVVPIPDTLADNEAATFGVAYLTAWHSLCEVGRLSPGERVLIHSAT Rv2933|M.tuberculosis_H37Rv TIADLVVPIPDTLADNEAATFGVAYLTAWHSLCEVGRLSPGERVLIHSAT MLBr_02355|M.leprae_Br4923 TIADLVVPIPDTLSDHEAATFGVAYLTAWHCLCEVGRLSPGERVLIHSAT MMAR_1774|M.marinum_M TIADLVVPIPDTLPDNEAATFGIAYLTAWHSLCEVGRLSPGERVLIHSAT MUL_2017|M.ulcerans_Agy99 TIADLVVPIPDTLPDNEAATFGIAYLTAWHSLCEVGRLSPGERVLIHSAT MAV_1763|M.avium_104 VPVQLLAPIPDGVSAVDAATIPAAALTAR-LAFDWAQLKPGDRVLIHAAS Mflv_2449|M.gilvum_PYR-GCK VDAAALAPIPDGVDARTAAAFGVAYRTAYHTLRSVARVSEGDELVVLGAG Mvan_4202|M.vanbaalenii_PYR-1 ADAAGLTPVPDGVDARTAAAFGVAHRTAYHALRSTARLSAGDELVVLGAG MAB_3622c|M.abscessus_ATCC_199 MPAAHLIGLPDGISCDTAAAITMRGLTTAYLLRRIHPLRAGDTVLLHAAA TH_3440|M.thermoresistible__bu APADYVAYVPDGVAPDTVASALLKGMTAHYLIKSVYEVQRGDTILVHAGA MSMEG_4067|M.smegmatis_MC2_155 VPAQRVIGWPDGVDLVGAAALWVSYSTAYGALIEKARIRPGDHVLITAAS . : ** : .*: *: : *: ::: .. Mb2958|M.bovis_AF2122/97 GGVGMAAVSIAKMIGARIYTTAGSDAKREMLSRLGVEYVGDSRS--VDFA Rv2933|M.tuberculosis_H37Rv GGVGMAAVSIAKMIGARIYTTAGSDAKREMLSRLGVEYVGDSRS--VDFA MLBr_02355|M.leprae_Br4923 GGVGMAAVSIAKMLGARIYTTAGSDAKRQMLSELGVEYVGDSRS--VDFA MMAR_1774|M.marinum_M GGVGMAAVSIAKMIGARIYTTAGSDAKREMLSSLGVDYVGDSRT--VDFA MUL_2017|M.ulcerans_Agy99 GGVGMAAVSIAKMIGARIYTTAGSDAKREMLSSLGVDYVGDSRT--VDFA MAV_1763|M.avium_104 GGVGLAAIQLAQRHGATVFATAS-TYKRATLRKLGVEYVYDSRS--TDFA Mflv_2449|M.gilvum_PYR-GCK GGVGLAAVQLGVALGANVTAVASSAEKLAAAAEYGAAHLVDHRE--QDLR Mvan_4202|M.vanbaalenii_PYR-1 GGVGLATVQLGVALGARVTAVASSNEKLAVAGGYGAATLINHRD--GELR MAB_3622c|M.abscessus_ATCC_199 GGVGLLFLQWANLLGVNVIGTVSNEEKAEIARANGCAHVLIYPR--EDVP TH_3440|M.thermoresistible__bu GGVGLILTQWATHLGARVITTVSTPQKAELSRKAGAAEVLDYPTDPEEFG MSMEG_4067|M.smegmatis_MC2_155 SGVGLAAIQVANQIGAIPLAVTRSPDKKSALLNAGAAAVFTSDV--EDVA .***: . . *. .. * * : :. Mb2958|M.bovis_AF2122/97 DEILELTDGYGVDVVLNSLAGEAIQRG-VQILAPGGRFIELGKKDVYADA Rv2933|M.tuberculosis_H37Rv DEILELTDGYGVDVVLNSLAGEAIQRG-VQILAPGGRFIELGKKDVYADA MLBr_02355|M.leprae_Br4923 DEILELTHGYGVDIILNSLADKAIQRG-VQILAPGGRFIEIGKKDVYDDA MMAR_1774|M.marinum_M DEILELTDGYGVDIVLNSLAGEAIQRG-VQILAPGGRFIELGKKDVHANA MUL_2017|M.ulcerans_Agy99 DEILELTDGYGVDIVLNSLAGEAIQRG-VQILAPGGRFIELGKKDVHANA MAV_1763|M.avium_104 DQILADTDGAGVDVVLNSLTNEGFIEATVRATAQHGRFVEIAKRDIWTRE Mflv_2449|M.gilvum_PYR-GCK AALRTAVP-DGADVVIDPVGGRLSEPA-LRSLGRGGRFVTVGFASGEIPR Mvan_4202|M.vanbaalenii_PYR-1 QALRQAIP-DGADVVVDPVGGDVSEPA-LRSLGRGGRFVSVGFASGVIPR MAB_3622c|M.abscessus_ATCC_199 RRVREITGGVGVPVVYDGIGKATYQSS-LDSLSPRGLLVCFGTASGPIPS TH_3440|M.thermoresistible__bu ARIRDLTGGEGVPVVYDGVGRSTFDAS-LASLAVRGTLALFGAASGPVPP MSMEG_4067|M.smegmatis_MC2_155 SAAKSYTGGLGVDVIVDSVMGPGLAQL-AGAAKAGGTLVTVGWLDPRPAS *. :: : : * : .. . Mb2958|M.bovis_AF2122/97 SLGLAALAKSASFSVVDLDLNLKLQPARYRQLLQHILQHVADGKLEVLPV Rv2933|M.tuberculosis_H37Rv SLGLAALAKSASFSVVDLDLNLKLQPARYRQLLQHILQHVADGKLEVLPV MLBr_02355|M.leprae_Br4923 NLGLAALAKSASFSVVDLDLNLKLHPARYRQLLQHILAHVADGRLPVLPV MMAR_1774|M.marinum_M NLGLAALAKSASFSVVDLDLNLKLQPAKYRELLQEILEHVADGALEVLPV MUL_2017|M.ulcerans_Agy99 NLGLAALAKSASFSVVDLDLNLKLQPAKYRELLQEILEHVADGTLEVLPV MAV_1763|M.avium_104 QM--AAARPDIAYEIVALDWACVEQPEHIHALLTEVSDGLASGEWRPLPA Mflv_2449|M.gilvum_PYR-GCK IPLNLVLLKG---VQVLGFQFQDVPGDEFVRNDHELRALLSARRVTPHVG Mvan_4202|M.vanbaalenii_PYR-1 IPLNLVLIKG---VHVLGFQFQDVPADEFTRNEVELRELLVSGRVKPHVG MAB_3622c|M.abscessus_ATCC_199 IDAMQLAAKGSLFVTRPALADYIADPAERAELAGELFGHVGAGRIRVDIG TH_3440|M.thermoresistible__bu FDPQRLNAAGSVYLTRPSLVHFTRTPDEFGWRAGEFLSAVADGTLTITVG MSMEG_4067|M.smegmatis_MC2_155 FPMGQLTIYP------YASFEHTLDPAAVQRIAAFLRAGLRSGALQPTVD . : Mb2958|M.bovis_AF2122/97 TAFSLHDAADAFRLMASGKHTGKIVISIPQHGSIEAIAAPPPLPLVSRDG Rv2933|M.tuberculosis_H37Rv TAFSLHDAADAFRLMASGKHTGKIVISIPQHGSIEAIAAPPPLPLVSRDG MLBr_02355|M.leprae_Br4923 TEFSLHNAADAFRLMASGKHTGKIVISIPYEGNIEAIASPPPVPLVSQDG MMAR_1774|M.marinum_M TEFGLRDAADGFRLMASGKHTGKIVISIPDGGTVEAIASPPPEPLVSPEG MUL_2017|M.ulcerans_Agy99 TEFGLRDAADGFRLMASGKHTGKIVISIPDGSTVETIASPPPEPLVSPEG MAV_1763|M.avium_104 EIYPLAEAKTAFRRMQQARHIGKIVLQMPKP------------LQPRGDR Mflv_2449|M.gilvum_PYR-GCK AVYPLEEVAAALRHVGEGRAIGKVLIDVPA-------------------- Mvan_4202|M.vanbaalenii_PYR-1 AVYSLDDTVAALRHVSDGRAIGKVVIDLS--------------------- MAB_3622c|M.abscessus_ATCC_199 RRYSLEEAVTAHRDMESGAIIGQSIFAL---------------------- TH_3440|M.thermoresistible__bu ERYPLAEAERAHRDLEGRKTVGSVVLLP---------------------- MSMEG_4067|M.smegmatis_MC2_155 RVFSFADIAEAHRYLEKGQHIGKIVVTHSHDR------------------ : : : . * : *. :. Mb2958|M.bovis_AF2122/97 GYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAIAELNA-S Rv2933|M.tuberculosis_H37Rv GYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSAPSDEVAAAIAELNA-S MLBr_02355|M.leprae_Br4923 GYLVVGGMGGLGFVFARWLAEQGAGLIVLNGRSSPSDDVTAAIADLTA-A MMAR_1774|M.marinum_M GYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSEPSDDVRAAIADLSS-G MUL_2017|M.ulcerans_Agy99 GYLIVGGMGGLGFVVARWLAEQGAGLIVLNGRSEPSDDVRAAIADLSS-G MAV_1763|M.avium_104 SYLITGGLGAIGLHLAAYLAQLGAGEIVLTSRRAPDAAAWRAIDDITERY Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 GSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMT Rv2933|M.tuberculosis_H37Rv GSRIEVITGDITEPDTAERLVRAVEDAGFRLAGVVHSAMVLADEIVLNMT MLBr_02355|M.leprae_Br4923 GHRIEVVTGDISEPGTADRLVHAVQSAGFRLAGVLHSAMVLADEIMLNMT MMAR_1774|M.marinum_M GTRIEVVTGDIAEPGTAERLVQTVQNSGFRLAGVLHSAMVLDDEIVLNMS MUL_2017|M.ulcerans_Agy99 GTRIEVVTGDIAEPGTAERLVQTVQNSGFRLAGVLHSAMVLDDEIVLNMS MAV_1763|M.avium_104 RCRVHTFAADVGDAAQVEQLLARIRAELPPLAGVAHLAGVLDDALLSQQS Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 DSAARRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAA Rv2933|M.tuberculosis_H37Rv DSAARRVFAPKVTGSWRLHVATAARDVDWWLTFSSAAALLGTPGQGAYAA MLBr_02355|M.leprae_Br4923 DSAARRVFVPKVTGSWRLHQATAAFEVDWWLTFSSASSLLGTPGQGAYAA MMAR_1774|M.marinum_M ESAARRVFTPKVAGSWRLHEATADLDLDWWLTFSSVASLLGAPGQGSYAA MUL_2017|M.ulcerans_Agy99 ESAARRVFTPKVAGSWRLHEATADLDLDWWLTFSSVASLLGAPGQGSYAA MAV_1763|M.avium_104 PERFRVALAPKAFGASYLDHATRTDDLDFFIVSSSVSSLLGSPGQANYST Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 ANSWVDGLVAHRRSAGLPAVGINWGPWADVGRAQFFKD---LGVEMINAE Rv2933|M.tuberculosis_H37Rv ANSWVDGLVAHRRSAGLPAVGINWGPWADVGRAQFFKD---LGVEMINAE MLBr_02355|M.leprae_Br4923 ANAWVDGLVAYRRSLGLPAVGINWGPWAEVGRAQFFAG---LGVSLLTAE MMAR_1774|M.marinum_M ANSFVDGLVAYRRSLGLPAVGINWGPWAEVGRAQFFAD---LGVSMITVE MUL_2017|M.ulcerans_Agy99 ANSFVDGLVAYRRSLGLPAVGINWGPWAEVGRAQFFAD---LGVSMITVE MAV_1763|M.avium_104 ANAWLDGLVAARQARGLPATGVNLGPWAQGGMASSEAARANIGAQGLIPL Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 QGLAAMQAVLTADRGRTGVFSLDARQWFQSFPAVAGSSLFAKLHDSAARK Rv2933|M.tuberculosis_H37Rv QGLAAMQAVLTADRGRTGVFSLDARQWFQSFPAVAGSSLFAKLHDSAARK MLBr_02355|M.leprae_Br4923 QGLAAMQTVLAADRAQTGVFSLDARQWFQSFPAVAGSSLFANLRDTATLK MMAR_1774|M.marinum_M QGLAAMQLVLSADRARTGVFILDARQWFQSFPAAAGSSLFSKLQESTTP- MUL_2017|M.ulcerans_Agy99 QGLAAMQLVLSADRARTGVFILDARQWFQSFPAAAGSSLFSKLQESTTP- MAV_1763|M.avium_104 EPTAALAALAEVVANGTGQATVIKANWQRAAKLLGG-ARPPILDLVLPSA Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 SGQRRGGGAIRAQLDALD---AAERPGHLASAIADEIRAVLRSGDPIDHH Rv2933|M.tuberculosis_H37Rv SGQRRGGGAIRAQLDALD---AAERPGHLASAIADEIRAVLRSGDPIDHH MLBr_02355|M.leprae_Br4923 SGERRGVGKIRAQLDVLD---AAERPGHLASAIADEIRAVLRSSDPIDHD MMAR_1774|M.marinum_M --ERRAGGAIRAELDALEGAAAAERPARLAAAIAGEIRAVLRSTEPIDVD MUL_2017|M.ulcerans_Agy99 --ERRAGGAIRAELDALERAAAAELPARLAGAIAGEIRAVLRSTEPIDVD MAV_1763|M.avium_104 VGEASGDSELLKQLQEIP---VAQRAAFITEFLQREVQGFLRLAQPPAAT Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 RPLETLGLDSLMGLELRNRLEASLG--ITLPVALVWAYPTISDLATALCE Rv2933|M.tuberculosis_H37Rv RPLETLGLDSLMGLELRNRLEASLG--ITLPVALVWAYPTISDLATALCE MLBr_02355|M.leprae_Br4923 RPLEALGLDSLMGLELRNRLEASLG--ITLPVALVWAYPTTADLAAALCE MMAR_1774|M.marinum_M RPMESLGLDSLMALELRNRLEASLG--TTLPAALVWAYPTITDLAGALCE MUL_2017|M.ulcerans_Agy99 RPMESLGLDSLMALELRNRLEASLG--TTLPAALVWAYPTITDLAGALCE MAV_1763|M.avium_104 SRFLDLGTDSLMAVELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLAG Mflv_2449|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 -------------------------------------------------- TH_3440|M.thermoresistible__bu -------------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 -------------------------------------------------- Mb2958|M.bovis_AF2122/97 RMDYATPAAAQEISDTEPELSDEEMDLLADLVDASELEAATRGES Rv2933|M.tuberculosis_H37Rv RMDYATPAAAQEISDTEPELSDEEMDLLADLVDASELEAATRGES MLBr_02355|M.leprae_Br4923 RMDYALPAEVQEATDTNAELSKAEMDLLSDLVEASELEAATRGES MMAR_1774|M.marinum_M RLGYAQLADVEQTPDAEAALSDEEMELLSDLVAASELETATGSSE MUL_2017|M.ulcerans_Agy99 RLGYAQLADVEQTPDAEAALSDEEMELLSDLVAARELETATGSSE MAV_1763|M.avium_104 -----QLPDAESEPGAAVAANPNPGSETGTGEAEPEREAAPEPS- Mflv_2449|M.gilvum_PYR-GCK --------------------------------------------- Mvan_4202|M.vanbaalenii_PYR-1 --------------------------------------------- MAB_3622c|M.abscessus_ATCC_199 --------------------------------------------- TH_3440|M.thermoresistible__bu --------------------------------------------- MSMEG_4067|M.smegmatis_MC2_155 ---------------------------------------------