For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TATPDRRAVITDALRKIDDLSARLEIAEKAGTEPIAVVGMGCRFPGGVDNPEQFWDLLHEGRSGIVRVPS QRWDADALYTDDHTLAGTICNREGGFLSTWEPSEFDAEFFSIPPREAAAMDPQQRLFLEVAWEALENAGI PPQTIRGTQTGVFVGVTAYDYMLMMSGAVRAEELDAYLLTGNSANFAAGRTAYLLGARGPAMVLDTACSS SLVAIHLACQSLRWRETDMALVGGTNLLLSPGTSIACSRWGMLSPEGQCKTFDADADGYVRSEGAGVVVL KRLSDAQRDGNRILAVVRGSAVNQDGASSGVTVPNGPAQQALLAQALDSAKLTPADIDYIEAHGTGTPLG DPIELDSLSKVFADREGREPLVLGAVKTNLGHLEAAAGIAGFMKSVLAVGHGRIPRNLNFRQLTPHASEG VSRLTIATEEMEWPATDQPRRAGVSSFGVSGTNAHVVIEQAPDPAPVPRDAAPAVSTLVVSGKTAQRVAA TAAALADWMEGPGSEVPLSDVAHTLNHHRARQPKFATVAAVDREQAITGLRALAAGEPATGVVGCPEKPL GPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAIAELEPVFLAEAGFSLHDVIADGKELEGIEQIQLGLIG MQLALTALWRHYGVTPDLVIGHSMGEVAATVVAGALTPAEGLRVTATRSRLMAPLSGQGTMAMLELDATA TEALIAGYPEVTLAIYASPRQTVIAGPPQMIDELIEQVRAQNRFAGRVNIEVAPHNPAMDALQPLMRSEL ADLTPRPPSIPIISTTYEDLESRPAFDAEHWATNMRNPVRFQQAITHAFNGADTAHHTFIEISAHPLLTH AISETLAASQDSAQGETDSGASYLSIGTLQRDAHDTLTFHTNFNATHTTRGPQTPHPAEPHPVLPTTPWQ HGQHWISSTTASRYATGSHPLLGIGVTDPTNGTRVWESQLGPDLLWLSDHVIDDLCVLPGSAYAEVALAA AMDTFKDAEGDQGSADPAGPDGSVASNAHQPWVIRELSLHQLLHVTDGTKLVTTLTGDEHTCRIEISTQS GASGWVKHASATLARHDASDSDAPRPAVEEAGAPTDELDPEQLYQRLRGAGQQHGPAFRGIVGLAVTESG AARADVRLPSSARIGYRGFALHPVMMDIAVQTLGATRMALELAEQQDSGHTLVLPIRFAGIHVYGDIAEG VRAIGSLAATDRPDRLVGRVTLVDPDGQPLLVIDEVEMAVLGSSASPTELTSRLFTLEWEPKPLDQTAAT PGAVLLIGDLGADDRLLPALQTSLTGSVAELDVVSPADAAKLRAAITRTDARWQDIVVVCPPRAVDEALP QDAQLDLTQQRTLMIADVAQTVTRMGARNSPRLWIVTRGAQQLSPADEVTLAQTQLRGIARVLTFEHPEL KTTLVDIEGDGEGSLTALTQELLAGADDDEISLRDGQRFVHRLVAAPTVGTGDLELESRRTVVNLDAGGA VQLRTDQPGRLDSLTVHQVKRCRPQGDQVEVRVAAAGLNFSDVLKAMGVYPGLDGAAPVIGGECVGYVTA IGDDVDSLEIGQRVIAFGPGTFGSHLGTIADLVVPIPDTLPDNEAATFGIAYLTAWHSLCEVGRLSPGER VLIHSATGGVGMAAVSIAKMIGARIYTTAGSDAKREMLSSLGVDYVGDSRTVDFADEILELTDGYGVDIV LNSLAGEAIQRGVQILAPGGRFIELGKKDVHANANLGLAALAKSASFSVVDLDLNLKLQPAKYRELLQEI LEHVADGALEVLPVTEFGLRDAADGFRLMASGKHTGKIVISIPDGGTVEAIASPPPEPLVSPEGGYLIVG GMGGLGFVVARWLAEQGAGLIVLNGRSEPSDDVRAAIADLSSGGTRIEVVTGDIAEPGTAERLVQTVQNS GFRLAGVLHSAMVLDDEIVLNMSESAARRVFTPKVAGSWRLHEATADLDLDWWLTFSSVASLLGAPGQGS YAAANSFVDGLVAYRRSLGLPAVGINWGPWAEVGRAQFFADLGVSMITVEQGLAAMQLVLSADRARTGVF ILDARQWFQSFPAAAGSSLFSKLQESTTPERRAGGAIRAELDALEGAAAAERPARLAAAIAGEIRAVLRS TEPIDVDRPMESLGLDSLMALELRNRLEASLGTTLPAALVWAYPTITDLAGALCERLGYAQLADVEQTPD AEAALSDEEMELLSDLVAASELETATGSSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1774 | ppsC | - | 100% (2201) | phenolpthiocerol synthesis type-I polyketide synthase PpsC |
| M. marinum M | MMAR_1767 | mas | 0.0 | 37.29% (2159) | multifunctional mycocerosic acid synthase membrane-associated |
| M. marinum M | MMAR_2344 | pks5_1 | 0.0 | 37.37% (2173) | polyketide synthase, Pks5_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2958 | ppsC | 0.0 | 76.31% (2220) | phenolpthiocerol synthesis type-I polyketide synthase PPSC |
| M. gilvum PYR-GCK | Mflv_3392 | - | 0.0 | 60.82% (998) | acyl transferase domain-containing protein |
| M. tuberculosis H37Rv | Rv2933 | ppsC | 0.0 | 76.31% (2220) | phenolpthiocerol synthesis type-I polyketide synthase PPSC |
| M. leprae Br4923 | MLBr_02355 | - | 0.0 | 75.20% (2222) | polyketide synthase |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 36.17% (2165) | polyketide synthase Pks5 |
| M. avium 104 | MAV_2370 | - | 0.0 | 36.86% (2173) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 37.70% (2175) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 37.65% (1883) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2017 | ppsC | 0.0 | 99.14% (2201) | phenolpthiocerol synthesis type-I polyketide synthase PpsC |
| M. vanbaalenii PYR-1 | Mvan_3125 | - | 0.0 | 64.32% (922) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1774|M.marinum_M -------MTATPDRRAVITDALRKIDDLSARLEIAEKAGTEPIAVVGMGC
MUL_2017|M.ulcerans_Agy99 -------MTATPDRRAVITDALRKIDDLSARLEIAEKAGTEPIAVVGMGC
Mb2958|M.bovis_AF2122/97 ------MTAATPDRRAIITEALHKIDDLTARLEIAEKSSSEPIAVIGMGC
Rv2933|M.tuberculosis_H37Rv ------MTAATPDRRAIITEALHKIDDLTARLEIAEKSSSEPIAVIGMGC
MLBr_02355|M.leprae_Br4923 ------MTASTPDRRAIITEALHKIDDLTARLEIAEKSSTEPIAVIGMGC
MAV_2370|M.avium_104 ---------------------------------------MVPVAVIGMAC
TH_4621|M.thermoresistible__bu -------------------------------VNIVGDTPVNAVAVIGMAC
MSMEG_4727|M.smegmatis_MC2_155 ----------------------------------MTQNCVAPVAIIGMAC
MAB_3148c|M.abscessus_ATCC_199 -----------------------------------------------MGC
Mflv_3392|M.gilvum_PYR-GCK MTVAS-GSPASPDRRAIITEALRKIDDLTARLAAAEKAETEPIAVVGIGC
Mvan_3125|M.vanbaalenii_PYR-1 MTQASSASPATPDRRAIITEALRKIDDLTARLAVAEKAETEPIAVVGIGC
:.*
MMAR_1774|M.marinum_M RFPGGVDNPEQFWDLLHEGRSGIVRVPSQRWDADALYTDDHTLAGTICNR
MUL_2017|M.ulcerans_Agy99 RFPGGVDNPEQFWDLLHEGRSGIVRVPSQRWDADALYTDDHTLAGTICNR
Mb2958|M.bovis_AF2122/97 RFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICST
Rv2933|M.tuberculosis_H37Rv RFPGGVNNPEQFWDLLCAGRSGIVRVPAQRWDADAYYCDDHTVPGTICST
MLBr_02355|M.leprae_Br4923 RFPGGVNNPEQFWDLLCDGRSGIVRVPSDRWDADAYYTDDHTVPGTICST
MAV_2370|M.avium_104 RLPGAVDSPERLWEALLRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSR
TH_4621|M.thermoresistible__bu RLPGGIDSPQRLWEALLRGDDMVTEIPVDRWDADDYFDPEPGVPGRTVSR
MSMEG_4727|M.smegmatis_MC2_155 RLPGAINSPQQLWEALLRGDDFVTEIPTGRWDAEEYYDPEPGVPGRSVSK
MAB_3148c|M.abscessus_ATCC_199 RLPGGIESPEQFWQALLRGEDFITEVPPARWDLTEYYDPESGVPGKSPSK
Mflv_3392|M.gilvum_PYR-GCK RLPGGVENADGFWRFLSDGGNGVIRVPADRWDADAFYSADYTVPGTICNR
Mvan_3125|M.vanbaalenii_PYR-1 RLPGGVDNADDFWKLLCDGESGVIRVPADRWDADQYYSSDYSVPGTICNR
*:**.::..: :* * * . : .:* *** : : :.* .
MMAR_1774|M.marinum_M EGGFLSTWEPSEFDAEFFSIPPREAAAMDPQQRLFLEVAWEALENAGIPP
MUL_2017|M.ulcerans_Agy99 EGGFLSTWEPSEFDAEFFSIPPREAAAMDPQQRLFLEVAWEALENAGISP
Mb2958|M.bovis_AF2122/97 EGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQ
Rv2933|M.tuberculosis_H37Rv EGGFLTSWQPDEFDAEFFSISPREAAAMDPQQRLLIEVAWEALEDAGVPQ
MLBr_02355|M.leprae_Br4923 EGGFLTGWQPDEFDAEFFSISPREASAMDPQQRLLIEVAWEALEDAGVAP
MAV_2370|M.avium_104 WGAFID--DVAGFDPEFFGINEREATAMDPQHRLLLETSWEAMEHAGLTE
TH_4621|M.thermoresistible__bu WGAFLD--DVAGFDPEFFGISEREAISIDPQQRLLLETSWEAMEHAGLTP
MSMEG_4727|M.smegmatis_MC2_155 WGAFLD--DPAAFDPEFFGITEREAAAIDPQHRLLLETAWEAVEHSGLNP
MAB_3148c|M.abscessus_ATCC_199 WGAFLE--DVGGFDADFFSINEREAVSIDPQHRVLLETSWQAVEHAGIDP
Mflv_3392|M.gilvum_PYR-GCK EGGFLTSWQPDEFDAEFFSIAPREAAAMDPQQRLLLEVAWEALENAGINP
Mvan_3125|M.vanbaalenii_PYR-1 EGGFLTSWQPDEFDAEFFSIAPREAAAMDPQQRLLLEVAWEALEDAGINP
*.*: : **.:**.* *** ::***:*:::*.:*:*:*.:*:
MMAR_1774|M.marinum_M QTIRGTQTGVFVGVTAYDYMLMMSGAVRAEELDAYLLTGNSANFAAGRTA
MUL_2017|M.ulcerans_Agy99 QTIRGTQTGVFVGVTAYDYMLMMSGAVRAEELDAYLLTGNSANFAAGRTA
Mb2958|M.bovis_AF2122/97 HTIRGTQTSVFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLA
Rv2933|M.tuberculosis_H37Rv HTIRGTQTSVFVGVTAYDYMLTLAGRLRPVDLDAYIPTGNSANFAAGRLA
MLBr_02355|M.leprae_Br4923 HTIRGTQTSVFVGVTAYDYMLTLAGRLRPEDLDAYIPTGNSANFAAGRLA
MAV_2370|M.avium_104 ERVADSRTGVFIGLTHGDYQLLAADTRSVE--GAYGFSGSNFSLASGRIA
TH_4621|M.thermoresistible__bu ADVEGSSTGVFVGLSHDDYALLTSDAGALE--EAYGFTGSAFSMASGRIA
MSMEG_4727|M.smegmatis_MC2_155 AGLAGSATGVFMGLTHNDYAHLAADAKALE--GPYGFTGTSFSLASGRIA
MAB_3148c|M.abscessus_ATCC_199 RALAGSQTGVFVGVTHNDYQLVAADAADLG--GPYGFAGTNFCMASGRIS
Mflv_3392|M.gilvum_PYR-GCK RSLRGSATGVFIGLTTNDYYHSVVGRLRPEDIDPYIPFGNAPNFAAGRLS
Mvan_3125|M.vanbaalenii_PYR-1 RTLRGTSTGVFIGLTTNDYYHSVVGKLRPEDIDPYIPFGNAPNFAAGRLS
: .: *.**:*:: ** . .* *. :*:** :
MMAR_1774|M.marinum_M YLLGARGPAMVLDTACSSSLVAIHLACQSLRWRETDMALVGGTNLLLSPG
MUL_2017|M.ulcerans_Agy99 YLLGARGPAMVLDTACSSSLVAIHLACQSLRWRETDMALVGGTNLLLSPG
Mb2958|M.bovis_AF2122/97 YILGARGPAVVIDTACSSSLVAVHLACQSLRGRESDMALVGGTNLLLSPG
Rv2933|M.tuberculosis_H37Rv YILGARGPAVVIDTACSSSLVAVHLACQSLRGRESDMALVGGTNLLLSPG
MLBr_02355|M.leprae_Br4923 YILGVRGPAVVIDTACSSSLVAVHLACQSLRHRESDAALVGGTNLLLSPG
MAV_2370|M.avium_104 YALGVHGPALTVDTACSSGLTAIHLACRSLHEGESDLALAGGATLALDPR
TH_4621|M.thermoresistible__bu YRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGESDLALAGGAMVMLEPR
MSMEG_4727|M.smegmatis_MC2_155 YALGVHGPAITVDTACSSSLSAIHMACRSLHDGESDVALAGGVSVLLEPR
MAB_3148c|M.abscessus_ATCC_199 YALGVHGPSLTVDAGCAAGLATVHMGCQSLAAGESDLVLAGGVNLVLEPR
Mflv_3392|M.gilvum_PYR-GCK YFLGVRGPAVVSDTACSSSLVSIHLACQSLRRGESDHALAAGVNLILSPE
Mvan_3125|M.vanbaalenii_PYR-1 YFLGVRGPAVVSDTACSSSLVSIHLACQSLRRGESDHALAAGVNLILSPD
* **.:**::. *:.*::.* ::*:.*:** *:* .*..*. : *.*
MMAR_1774|M.marinum_M TSIACSRWGMLSPEGQCKTFDADADGYVRSEGAGVVVLKRLSDAQRDGNR
MUL_2017|M.ulcerans_Agy99 TSIACSRWGMLSPEGQCKTFDADADGYVRSEGAGVVVLKRLSDAQRDGNR
Mb2958|M.bovis_AF2122/97 PSIACSRWGMLSPEGRCKTFDASADGYVRGEGAAVVVLKRLDDAVRDGNR
Rv2933|M.tuberculosis_H37Rv PSIACSRWGMLSPEGRCKTFDASADGYVRGEGAAVVVLKRLDDAVRDGNR
MLBr_02355|M.leprae_Br4923 PSIACSRWGMLSPAGQCKAFDVSADGYVRGEGAGVVVLKRLDDAVRDGNR
MAV_2370|M.avium_104 KFSAGSAEGMLSPTGRCHAFDVAADGFVGGEGSVMLLLKRLNDALRDGDR
TH_4621|M.thermoresistible__bu KYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVMLLLKRLPDALRDNDR
MSMEG_4727|M.smegmatis_MC2_155 KAAGGSAAGMLSPTGHCHAFDTAADGFVSAEGCVVLTLKRLDDAVADGDR
MAB_3148c|M.abscessus_ATCC_199 RYVGASQQRMLSPTGRCHTFTGEADGFVMSEGCVMVLLKRLDDAVRDGDR
Mflv_3392|M.gilvum_PYR-GCK NNIACSRWGMLAPDGLCKTFDADANGYVRSEGAGVVVLKRLSDAVRDGDR
Mvan_3125|M.vanbaalenii_PYR-1 NNIACSRWGMLAPDGKCKTFDADADGYVRSEGAGVVVLKRLTDALRDGDR
. * **:* * *::* *:*:* .**. :: **** ** *.:*
MMAR_1774|M.marinum_M ILAVVRGSAVNQDGASSGVTVPNGPAQQALLAQALDSAKLTPADIDYIEA
MUL_2017|M.ulcerans_Agy99 ILAVVRGSAVNQDGASSGVTVPNGPAQQALLAQALDSAKLTPADIDYIEA
Mb2958|M.bovis_AF2122/97 ILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSKLTAADIDYVEA
Rv2933|M.tuberculosis_H37Rv ILAVVRGSAVNQDGASSGVTVPNGPAQQALLAKALTSSKLTAADIDYVEA
MLBr_02355|M.leprae_Br4923 ILAIVRGSAVNQDGASSGVTVPNGPAQQELLRTALASSKLTAADIDYIEA
MAV_2370|M.avium_104 ILAVVRGTAANQDGHTVNIATPSKTAQTAVYRAALAAAGVDAGTVGMVEA
TH_4621|M.thermoresistible__bu ILAVVRGTAANQDGRTENISTPSIQAQADVYRSALAVAGVDPATVGMVEA
MSMEG_4727|M.smegmatis_MC2_155 ILAVIRGTATNQDGRTVNIATPSADAQAKVYRMALKAAGVEPGTVGLVEA
MAB_3148c|M.abscessus_ATCC_199 ILAVVRGTASNQDGRTVNQSTPSSEAQAAACRTALAVAGVEADTVGLIEA
Mflv_3392|M.gilvum_PYR-GCK VLAVVRGSAVNQDGASSGQTVPNGPAQQELMRTALKSARLEPSDIDYIEA
Mvan_3125|M.vanbaalenii_PYR-1 VLAVVRGSAVNQDGASSGQTVPNGPAQQELMRKALETSRLEPSDIDYIEA
:**::**:* **** : . :.*. ** ** : : . :. :**
MMAR_1774|M.marinum_M HGTGTPLGDPIELDSLSKVFADR---EGREPLVLGAVKTNLGHLEAAAGI
MUL_2017|M.ulcerans_Agy99 HGTGTPLGDPIELDSLSKVFADR---EGREPLVLGAVKTNLGHLEAAAGI
Mb2958|M.bovis_AF2122/97 HGTGTPLGDPIELDSLSKVFSDR---AGSDQLVIGSVKTNLGHLEAAAGV
Rv2933|M.tuberculosis_H37Rv HGTGTPLGDPIELDSLSKVFSDR---AGSDQLVIGSVKTNLGHLEAAAGV
MLBr_02355|M.leprae_Br4923 HGTGTPLGDPIELDSLSKVFSDRQSRRGSVPLVIGSVKTNLGHLEAAAGI
MAV_2370|M.avium_104 HGPGTPVGDPIEYASLAEVYGIDG------PCALASVKTNFGHAQAASGA
TH_4621|M.thermoresistible__bu HGTGTPVGDPIEYNSLTQVYGKTG------PCALTSVKTNFGHAESAAGA
MSMEG_4727|M.smegmatis_MC2_155 HGTGTPVGDPLEFSSLAEVYGTDG------PCALGSIKTNFGHTQSAAGA
MAB_3148c|M.abscessus_ATCC_199 HGTGTPVGDPIEYTGLAQVYGVDG------PCAVGSVKTNFGHTMSAAGA
Mflv_3392|M.gilvum_PYR-GCK HGTGTSLGDPIELDALSAVYGDRK---DSAPLILGSVKTNLGHLESAAGV
Mvan_3125|M.vanbaalenii_PYR-1 HGTGTSLGDPIELDALSAVYGDRK---DSAPLVLGSVKTNLGHLESGAGV
**.**.:***:* .*: *:. : ::***:** :.:*
MMAR_1774|M.marinum_M AGFMKSVLAVGHGRIPRNLNFRQLTPHASEGVSRLTIATEEMEWPATDQ-
MUL_2017|M.ulcerans_Agy99 AGFMKSVLAVGHGRIPRNLNFRQLTPHASEGVSRLTIATEEMEWPATDQ-
Mb2958|M.bovis_AF2122/97 AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGR-
Rv2933|M.tuberculosis_H37Rv AGLMKAVLAVHNGYIPRHLNFHQLTPHASEAASRLRIAADGIDWPTTGR-
MLBr_02355|M.leprae_Br4923 AGFIKAVLAVQRGFIPRHLNFHQLTTHASEAASRLNIASEGLEWPTVGR-
MAV_2370|M.avium_104 LGMMKAILALQHGVVPRNLHFTQLPDDLARIDTKLFVPQQTTPWVSNGGH
TH_4621|M.thermoresistible__bu LGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQATTLWPVREGC
MSMEG_4727|M.smegmatis_MC2_155 LGVMKAVLALQHNVIPQNLHFTRLPDQMAEIETGLFVPETITPWPVREGQ
MAB_3148c|M.abscessus_ATCC_199 LGLMKIVLAVEHGVVPPNLHFTGIPDKLAPVKTNLFVPQTVIPWPGKAQG
Mflv_3392|M.gilvum_PYR-GCK TGFIKTVLSVHHGAIPKQLHFTKLTPQAGDGAKKFRIASEPLDWPA-TE-
Mvan_3125|M.vanbaalenii_PYR-1 TSFIKTVLSVHHGFIPKQLYFKKLTPQACEGAQKFRIASEPLEWPALTR-
..:* :*:: .. :* :* * :. . : :. *
MMAR_1774|M.marinum_M PRRAGVSSFGVSGTNAHVVIEQAPDPAPVP-----RDAAPAVSTLVVSGK
MUL_2017|M.ulcerans_Agy99 PRRAGVSSFGVSGTNAHVVIEQAPDPAPVP-----RDAAPAVSTLVVSGK
Mb2958|M.bovis_AF2122/97 PRRAGVSSFGVSGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGK
Rv2933|M.tuberculosis_H37Rv PRRAGVSSFGVSGTNAHVVIEQAPDPMAAAGTEPQRGPVPAVSTLVVFGK
MLBr_02355|M.leprae_Br4923 PRRAGVSSFGVSGTNAHVVLEQAPDPVAVPAPGPALRLVPAVSTLVVSGK
MAV_2370|M.avium_104 PRRAAVSSYGLSGTNVHAILEQAP-EPAPETVAPEGISAESPLLFPLSST
TH_4621|M.thermoresistible__bu PRRAAVSSYGMSGTNVHAVLEQAP-EPVQRPEESADTDAAGPLVFALSST
MSMEG_4727|M.smegmatis_MC2_155 PRRAAVSAYGLSGTNVHAVLEQAPESPAETAAEAISPKAGNALVFPVSAS
MAB_3148c|M.abscessus_ATCC_199 PRRAGVSAYGMSGSNVHAVVEQAP-PVESSTPPAVESPLGSQLIFPVSST
Mflv_3392|M.gilvum_PYR-GCK IRRAAVSSFGVSGTNAHIVVEQAPEPAEVPAA----QQEPPVSTLVVTGK
Mvan_3125|M.vanbaalenii_PYR-1 PRRAAVSGFGVSGTNAHIVIEQAPE-AEAVAP----QPEPPVSTLVVTGK
***.**.:*:**:*.* ::**** : : ..
MMAR_1774|M.marinum_M TAQRVAATAAALADWMEGPGS------EVPLSDVAHTLNHHRARQPKFAT
MUL_2017|M.ulcerans_Agy99 TAQRVAATAAALADWMEGPGS------EVPLSDVAHTLNHHRARQPKFAT
Mb2958|M.bovis_AF2122/97 TAPRVAATASVLADWLDGPGA------AVPLADVAHTLNHHRARQTRFGT
Rv2933|M.tuberculosis_H37Rv TAPRVAATASVLADWLDGPGA------AVPLADVAHTLNHHRARQTRFGT
MLBr_02355|M.leprae_Br4923 TVQRVAATASVLADWMEGPGA------AVPLTDVAHTLNHHRARHTKFGT
MAV_2370|M.avium_104 SADELRRTAGRLADWVHAHGD------LALP-DLAYTLARRRVHRPVRTA
TH_4621|M.thermoresistible__bu SAEELRRTAGRLAEWVEAHTD------EVVPADLAYTLARRRAHRPVRTT
MSMEG_4727|M.smegmatis_MC2_155 SADALRSTAQHLADWLLRSGDGNGRGPAIDLGDLAYTLARRRGFRAARSA
MAB_3148c|M.abscessus_ATCC_199 SAEELRRTAARLADWVAERPE-------VAPGDVGYTLARRRAHRSVRTA
Mflv_3392|M.gilvum_PYR-GCK TPARIASLAGRLADWLQTPEAA-----EPTLADIAETLNHRRAQHTRFAT
Mvan_3125|M.vanbaalenii_PYR-1 TAPRIASLAGRLADWLQMPEAA-----SVSLADVAETLNHHRAQHTKFAT
: : * **:*: *:. ** ::* :. :
MMAR_1774|M.marinum_M VAAVDREQAITGLRALAAGEPATGVVGCPEKPLGPGTVFVYSGRGSQWAG
MUL_2017|M.ulcerans_Agy99 VAAVDREQAITGLRALAAGEPATGVVGCPEKPLGPGTVFVYSGRGSQWAG
Mb2958|M.bovis_AF2122/97 VAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGTVFVYSGRGSQWAG
Rv2933|M.tuberculosis_H37Rv VAAVDRRQAVIGLRALAAGQSAPGVVAPREGSIGGGTVFVYSGRGSQWAG
MLBr_02355|M.leprae_Br4923 VAAVDRGQAVAGLRALAAGQSTSGVVAPRDSVVGPGTVFVYSGRGSQWAG
MAV_2370|M.avium_104 VLAGDRAQLIEALREVADGDTPYPAAVGRGD---RGPVWVFSGQGSQWAA
TH_4621|M.thermoresistible__bu VIADGVEALTAGLREVADGDAPYQPAVGMDD---KAPVWVFSGQGSQWAG
MSMEG_4727|M.smegmatis_MC2_155 VLAGDRGTLVEGLRQIADGEAMPQQAVTNDD---RGPVWVFSGQGSQWAS
MAB_3148c|M.abscessus_ATCC_199 VVADGADELIDALRGVAEGDAPYPAAVAQDD---RGPVWLFSGQGSQWAG
Mflv_3392|M.gilvum_PYR-GCK VAAADRDQAIAGLRALAGGYPAPGVVGPNDPALGTGTVFLYSGQGSQWAG
Mvan_3125|M.vanbaalenii_PYR-1 VTAADREQAVAGLRALAEGYPAPGVVPAHDGACGSGTVFLYSGQGSQWAG
* * . .** :* * . . ..*:::**:*****.
MMAR_1774|M.marinum_M MGRQLLADEPAFAAAIAELEPVFLAEAGFSLHDVIADGKELEGIEQIQLG
MUL_2017|M.ulcerans_Agy99 MGRQLLADEPAFAAAIAELEPVFLAEAGFSLHDVIADGKELEGIEQIQLG
Mb2958|M.bovis_AF2122/97 MGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQIQLG
Rv2933|M.tuberculosis_H37Rv MGRQLLADEPAFAAAIAELEPEFVAQGGFSLRDVIAGGKELVGIEQIQLG
MLBr_02355|M.leprae_Br4923 MGRQLMADEPAFAEAIAKLEHEFVVQAGFSLHEVIANGKELVGIEQIQLG
MAV_2370|M.avium_104 MGADLLATEPVFAATVAQAEPLIARESGFSVAEAMSAPQTVTGQDRVQPT
TH_4621|M.thermoresistible__bu MGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTGIDRVQPT
MSMEG_4727|M.smegmatis_MC2_155 MGAELLDREPAFAAAIAELEPLIAAESDFSVTEALTASETVTGIDRVQPT
MAB_3148c|M.abscessus_ATCC_199 MGAELLGKEPVFAETIARLEPLIHAESGFSVTDAISAPETVTGIDRVQPT
Mflv_3392|M.gilvum_PYR-GCK MGKRLLADEPAFAAAVDELEPDFVAQVGFSLRDVLTSGETVVGIDRIQPV
Mvan_3125|M.vanbaalenii_PYR-1 MGRRLLADEPAFAAAVDELEPDFVAAAGFSLRDVLTSGETVVGIDRIQPV
** *: * .** : . * . .**: :.:: : : * :::*
MMAR_1774|M.marinum_M LIGMQLALTALWRHYGVTPDLVIGHSMGEVAATVVAGALTPAEGLRVTAT
MUL_2017|M.ulcerans_Agy99 LIGMQLALTALWRHYGVTPDLVIGHSMGEVAAAVVAGALTPAEGLRVTAT
Mb2958|M.bovis_AF2122/97 LIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAV
Rv2933|M.tuberculosis_H37Rv LIGMQLALTALWRSYGVTPDAVIGHSMGEVAAAVVAGALTPAQGLRVTAV
MLBr_02355|M.leprae_Br4923 LMGMQLALTELWRSYGVEPDAVIGHSMGEVAAAVVAGALTPTQGLRVTAT
MAV_2370|M.avium_104 LFTMQVALAATMKAHGVRPGAVIGHSLGEAAAAVVAGALSLEDGARVICR
TH_4621|M.thermoresistible__bu LFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICR
MSMEG_4727|M.smegmatis_MC2_155 IFAVQVALAAAMRSHGVVPGAVIGHSMGEVAASVVSGALSLEDGVKVICR
MAB_3148c|M.abscessus_ATCC_199 LFAMQVSLAATLASYGVRPGAVIGHSMGEVAAAVVSEALSLEDGVKVICR
Mflv_3392|M.gilvum_PYR-GCK LVGVQLALTALWRSYGVTPDAVIGHSMGEVTAAVVSGALSPADGLKVIAT
Mvan_3125|M.vanbaalenii_PYR-1 LVGVQLALTKLWQSYGVNPDAVIGHSMGEVTAAVVAGALSPADGLKVIAT
:. :*::*: :** *. *****:**.:*:**: **: :* :* .
MMAR_1774|M.marinum_M RSRLMAPLSGQGTMAMLELDATATEALIAG--YPEVTLAIYASPRQTVIA
MUL_2017|M.ulcerans_Agy99 RSRLMAPLSGQGTMAMLELDATATEALIAG--YPEVTLAIYASPRQTVIA
Mb2958|M.bovis_AF2122/97 RSRLMAPLSGQGTMALLELDAEATEALIAD--YPEVSLGIYASPRQTVIS
Rv2933|M.tuberculosis_H37Rv RSRLMAPLSGQGTMALLELDAEATEALIAD--YPEVSLGIYASPRQTVIS
MLBr_02355|M.leprae_Br4923 RSRLMAPLSGQGTMALLELDAVATEALIAD--YPQVSLGIYASPRQTVIA
MAV_2370|M.avium_104 RSRLMSRVAGTGATASVELPAQQVLSELTARGISDVVVAVVASPQSTVIA
TH_4621|M.thermoresistible__bu RSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIG
MSMEG_4727|M.smegmatis_MC2_155 RTRLMTRIAGSGAMAMVELPAQQVLSELASRGVDDVVLSVVASPQSTVVG
MAB_3148c|M.abscessus_ATCC_199 RSQLMLRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQSTVVG
Mflv_3392|M.gilvum_PYR-GCK RSRLMKRLSGQGAMALLELDAEAAEKLIAG--YDGLTVAVYASAHQTVIA
Mvan_3125|M.vanbaalenii_PYR-1 RSRLMKRLSGQGAMALLELDAEAAEQLIAN--YSGLTVAVYASPHQTVIA
*::* ::* *: * ::* * . :: : :.: **...**:.
MMAR_1774|M.marinum_M GPPQMIDELIEQVRAQNRFAGRVNIEVAPHNPAMDALQPLMRSELADLTP
MUL_2017|M.ulcerans_Agy99 GPPQMIDELIEQVRAQNRFAGRVNIEVAPHNPAMDALQPLMRSELADLTP
Mb2958|M.bovis_AF2122/97 GPPLLIDELIDKVRQQNGFATRVNIEVAPHNPAMDALQPAMRSELADLTP
Rv2933|M.tuberculosis_H37Rv GPPLLIDELIDKVRQQNGFATRVNIEVAPHNPAMDALQPAMRSELADLTP
MLBr_02355|M.leprae_Br4923 GPTAMIDALIDKVRQQDGFATRVNIEVAPHNPAMDALQPQMRSELADLTP
MAV_2370|M.avium_104 GAAPTVRDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLTDALAEISP
TH_4621|M.thermoresistible__bu GATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQP
MSMEG_4727|M.smegmatis_MC2_155 GATASVRELIEMWESRGVMAREIAVDVASHSPQVDPILDDLIEALADLDP
MAB_3148c|M.abscessus_ATCC_199 GATETVRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALEDLTP
Mflv_3392|M.gilvum_PYR-GCK GPPDQVDAAIAVVDAQDKLARRVDVDVASHHPIVDPILEDLRSELAGLQP
Mvan_3125|M.vanbaalenii_PYR-1 GPPEQVDAAIAEVDKLDKLARRVDVDVASHHPIIDPILDDLRAELADLKP
*.. : : . :* .: :** * * :*.: : * : *
MMAR_1774|M.marinum_M RPPSIPIISTTYEDLE----SRPAFDAEHWATNMRNPVRFQQAITHAFNG
MUL_2017|M.ulcerans_Agy99 RPPSTPIISTTYEDLE----SRPAFDAEHWATNMRNPVRFQQAITHAFNG
Mb2958|M.bovis_AF2122/97 QPPTIPIISTTYADLGISLGSGPRFDAEHWATNMRNPVRFHQAIAHA---
Rv2933|M.tuberculosis_H37Rv QPPTIPIISTTYADLGISLGSGPRFDAEHWATNMRNPVRFHQAIAHA---
MLBr_02355|M.leprae_Br4923 QQPTIPIISTTYEDF----GSTPVFDVEHWATNMRNPVRFQQAITHASSG
MAV_2370|M.avium_104 RPPEVPYYSATLFDPR----EQPVCDARYWANNMRRMVRFATAVQAA---
TH_4621|M.thermoresistible__bu MTPTVPYYSATSYDPR----EKPVCDADYWVDNLRHEVRFAAAVQAA---
MSMEG_4727|M.smegmatis_MC2_155 AEPEIPYYSATLYDPR----DYADYDAYYWADNLRHTVRFSAAVQAA---
MAB_3148c|M.abscessus_ATCC_199 RTPVVPLYSSVSFDPR----ERPIMDADYWVDNLRHTVRFAAAVQAA---
Mflv_3392|M.gilvum_PYR-GCK RTPTVPIIVTTDGRPT---DGSCVFDADHWVANLRNPVRFARAVATAG--
Mvan_3125|M.vanbaalenii_PYR-1 RQPSIPIIVTTDQRPT---DGTCVFDADHWVANLRNPVRFARAVATAG--
* * :. *. :*. *:*. *** *: *
MMAR_1774|M.marinum_M ADTAHHTFIEISAHPLLTHAISETLAASQDSAQGETDSGASYLSIGTLQR
MUL_2017|M.ulcerans_Agy99 ADTAHHTFIEISAHPLLTHAISETLAANQDSAQGETDSGASYLSIGTLQR
Mb2958|M.bovis_AF2122/97 -GADHHTFIEISAHPLLTHSISDTLR---ASYDVDN-----YLSIGTLQR
Rv2933|M.tuberculosis_H37Rv -GADHHTFIEISAHPLLTHSISDTLR---ASYDVDN-----YLSIGTLQR
MLBr_02355|M.leprae_Br4923 VGGDYHTFIEISAHPLLTHSISDILCS-IAGTAEENAVGAGYLSIGTLQR
MAV_2370|M.avium_104 LEDGYRVFAELAPHPLLVRALEQTARS-------REIPMAALAGMRRGQA
TH_4621|M.thermoresistible__bu LEDGFRVFGELSPHPLLTRAVEQTARG-------LDMPVAALPAMRREQE
MSMEG_4727|M.smegmatis_MC2_155 LEDGHRVFAELSPHPLLTHPVEQTARS-------LDMPLAVFAAMRRQQE
MAB_3148c|M.abscessus_ATCC_199 LDDGYRVFGELAPHPLLVYPAEQTARS-------LDIPMVALAGMRREQE
Mflv_3392|M.gilvum_PYR-GCK --ADASIFVEVSPHPLLSYAIKDTLTG------------PHRN-LPTLQR
Mvan_3125|M.vanbaalenii_PYR-1 --ADKAVFVEVSPHPLLGYAIKDTLAG------------THHHSIATLQR
* *::.**** . .: : *
MMAR_1774|M.marinum_M DAHDTLTFHTNFNATHTTRGPQTPHPAEPHPVLPTTPWQHGQHWISSTTA
MUL_2017|M.ulcerans_Agy99 DAHDTLTFHTNFNATHTTHGPQTPHPAEPHPVLPTTPWQHGQHWISSTTA
Mb2958|M.bovis_AF2122/97 DAHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSA
Rv2933|M.tuberculosis_H37Rv DAHDTLEFHTNLNTTHTTHPPQTPHPPEPHPVLPTTPWQHTQHWITATSA
MLBr_02355|M.leprae_Br4923 DAHDTLEFHTNLNATHTSRPPRTPHPPEPHPVLPITPWQHTRHWISAMSA
MAV_2370|M.avium_104 LPHGLRGFVADLHNAGAAVDFSVLYPTGRLVDAPLPTWTHRRLWLTDGGL
TH_4621|M.thermoresistible__bu MPHGVRTMVGDLFAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENG
MSMEG_4727|M.smegmatis_MC2_155 MPHGLLGFVADLHSAGAAVDFSVLYPTGRLLDAPLPAWTHSTLLLDR-EL
MAB_3148c|M.abscessus_ATCC_199 LPHGLRDFVGDLYTAGGAVDFSVLYPTGQLVDVPLPSWTRRSYLLDLSAQ
Mflv_3392|M.gilvum_PYR-GCK DTNDTVTFHTNLNATHTVRPPKTPQRGGPRVQLPATPWHHAHHWIHIAKP
Mvan_3125|M.vanbaalenii_PYR-1 DANDTVTFHTNLNATHTVRPPKTPAR-STRVQIPTTPWHHTHHWIHTSSA
.:. : :: : . * ..* : :
MMAR_1774|M.marinum_M SRYATG-----SHPLLGIGVTDPTN-GTRVWESQLGP-DLLWLSDHVIDD
MUL_2017|M.ulcerans_Agy99 SRYATG-----SHPLLGIGVTDPTN-GTRVWESQLGP-DLLWLGDHVIDD
Mb2958|M.bovis_AF2122/97 AYHRPD-----THPLLGVGVTDPTN-GTRVWESELDP-DLLWLADHVIDD
Rv2933|M.tuberculosis_H37Rv AYHRPD-----THPLLGVGVTDPTN-GTRVWESELDP-DLLWLADHVIDD
MLBr_02355|M.leprae_Br4923 AYHRAD-----THPLLGVGVTDPTS-GTRVWESQLGP-DLLWLGDHVIDD
MAV_2370|M.avium_104 ESPTHGGCTVAVHPLLGPHVHLQEEPERHLWQADVGTAAQPWLADHQIRN
TH_4621|M.thermoresistible__bu EQQTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHT
MSMEG_4727|M.smegmatis_MC2_155 ESSAPGVPSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQ
MAB_3148c|M.abscessus_ATCC_199 AQQGHGTHTVAVHPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRH
Mflv_3392|M.gilvum_PYR-GCK DTVAHT------GTGPPAGTALAEG-EKHEWFH-----TLTWPVRDLPQG
Mvan_3125|M.vanbaalenii_PYR-1 DVVQDK------GIP----VSLAEG-EKHEWFH-----QLSWPVRELPAG
. : * * .
MMAR_1774|M.marinum_M LCVLPGSAYAEVALAAAMDTFKDAEGDQGSADPAGPDGSVASNAHQPWVI
MUL_2017|M.ulcerans_Agy99 LCVLPGSAYAEVALAAAMDTFKDAEGDQGSADPAGPDGSVASNAHQPWVI
Mb2958|M.bovis_AF2122/97 LVVLPGAAYAEIALAAATDTFA-------------------VEQDQPWMI
Rv2933|M.tuberculosis_H37Rv LVVLPGAAYAEIALAAATDTFA-------------------VEQDQPWMI
MLBr_02355|M.leprae_Br4923 LCVLPGAAYAEVALAAATDTFPNER----------------VEGDQPWMI
MAV_2370|M.avium_104 VVVLPGAAYCEMALAAARSVLGAT-----------------------AEV
TH_4621|M.thermoresistible__bu VAALPGAAYCEMALAAAREVIDSDG----------------------VEV
MSMEG_4727|M.smegmatis_MC2_155 VAVLPGAAYCEMALAAVTPVLGDT-----------------------GEV
MAB_3148c|M.abscessus_ATCC_199 VAVYPGAAYCEMALSAAAAVFGEG-----------------------SAV
Mflv_3392|M.gilvum_PYR-GCK GTDVPWLVLGDDDG--LADLLGTGS-------------------------
Mvan_3125|M.vanbaalenii_PYR-1 STEVSWLVFTDKAGTDLAELLGPGS-------------------------
. . : :
MMAR_1774|M.marinum_M RELSLHQLLHVTDGTKLVTTLTGDEHTCRIEISTQSGASGWVKHASATLA
MUL_2017|M.ulcerans_Agy99 RELSLHQLLHVTDGTKLVTTLTGDEHTCRIEISTQSGASGWVKHASATLA
Mb2958|M.bovis_AF2122/97 SELDLRQMLHVTPGTVLVTTLTGDEQRCQVEIRTRSGSSGWTTHATATVA
Rv2933|M.tuberculosis_H37Rv SELDLRQMLHVTPGTVLVTTLTGDEQRCQVEIRTRSGSSGWTTHATATVA
MLBr_02355|M.leprae_Br4923 YELDLHQVLHVTEGTVLVTTLTGDQQRCRIEMRTRNGFSGWTTHATATVG
MAV_2370|M.avium_104 RDIRFEQALLLDEQTTVDASASVSSPGVLHFTVQSHQGGEQARHASAVLG
TH_4621|M.thermoresistible__bu RDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVETAKDGEHERRATAVLG
MSMEG_4727|M.smegmatis_MC2_155 HDLKFHDMLLLDDATPVWVSAAVTAPGTAEFGVETHQSGDRTQRATAVLR
MAB_3148c|M.abscessus_ATCC_199 QSISFEQLLTLGESTPISATATAKSADILEFVVETHDEGDVVKRATAVLG
Mflv_3392|M.gilvum_PYR-GCK ---RTAPLSVLDDDGDIAARLHPLLSDVRHVVYLPATEAARFDAAPSYRT
Mvan_3125|M.vanbaalenii_PYR-1 ---RALPLSVLDD----ADALSAALPGVEHVVYAPPVSGQRFHAEPSYAV
: . .:
MMAR_1774|M.marinum_M RHDASDSDAPR--PAVEEAGAPTDELDPEQLYQRLRGAGQQHGPAFRGIV
MUL_2017|M.ulcerans_Agy99 RHDASDSDAPR--PAVEKAGAPTDELDPEQLYQRLRGAGQQHGPAFRGIV
Mb2958|M.bovis_AF2122/97 RAEPLAPLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIV
Rv2933|M.tuberculosis_H37Rv RAEPLAPLDHEGQRREVTTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIV
MLBr_02355|M.leprae_Br4923 PAESVQPSDRE--ERTATPVDVVDELGPEDLYQRLCSAGQQHGPAFQGIV
MAV_2370|M.avium_104 AATD-EQPAAH--DLSALLTAHPHDDDGDEVRRRMDRRGVQYGPAFAGLG
TH_4621|M.thermoresistible__bu AADDTEPPQAH--DIDALLAEHPTRIEGDELRQWFDQRGVQFGPAFTGLT
MSMEG_4727|M.smegmatis_MC2_155 GDVDAERPAAH--SIDALLAAHPNRVDGDELRAGFGTVGIGHGAAFAGLS
MAB_3148c|M.abscessus_ATCC_199 NGGDVDMPIAY--DLSALRAEHPHRESGDDLRASFDERGVQYGPAFQGLA
Mflv_3392|M.gilvum_PYR-GCK FH------------------------------------------QLRRLV
Mvan_3125|M.vanbaalenii_PYR-1 FG------------------------------------------QLRRLV
: :
MMAR_1774|M.marinum_M GLAVTE--SGAARADVRLPSSARIGYRGFALHPVMMDIAVQTLGATRMAL
MUL_2017|M.ulcerans_Agy99 GLAVTG--SGAARADVRLPSSARIGYRGFALHPVMMDIAVQTLGATRMAL
Mb2958|M.bovis_AF2122/97 GLAVTQ--AGVARAQVRLPASARTGSREFMLHPVMMDIALQTLGATRTAT
Rv2933|M.tuberculosis_H37Rv GLAVTQ--AGVARAQVRLPASARTGSREFMLHPVMMDIALQTLGATRTAT
MLBr_02355|M.leprae_Br4923 GLAVEE--SGAARAEVRLPSSARMGFRDFLLHPVMMDIALQTLGATRMAT
MAV_2370|M.avium_104 AVHSGDETGT-VLAEVALPRQIRSQQAAYGAHPALLDACFQSVEAHPAVR
TH_4621|M.thermoresistible__bu AARIPEGTVTSVLAEVGLPGQIRSQQAPYGIHPALLDACFQSVAAHPDVQ
MSMEG_4727|M.smegmatis_MC2_155 EAYVATAAEPTVVAAVALPGPLRSGQRGYTVHPALLDACFQSVIAHPEVQ
MAB_3148c|M.abscessus_ATCC_199 AAYRGDETVRSVLAEVTLPRDVRAQQGSYIVHPALLDACFQSVIALPDVQ
Mflv_3392|M.gilvum_PYR-GCK VALAATPDAPRLFVVTRNAQPVTDGDRANPAHAVLWGQGRTLALEHPEFW
Mvan_3125|M.vanbaalenii_PYR-1 VALAGAADSPKLFVVTRNAQPVADGDRANPAHAVLWGQGRTLALEHPEFW
. . . *..: .
MMAR_1774|M.marinum_M ELAEQ------QDSGHTLVLPIRFAGIHVYGDIAEGVRAIGSLAATDRPD
MUL_2017|M.ulcerans_Agy99 ELTEQ------QDSGHTLVLPIRFAGIHVYGDIAEGVRAIGSLAATDRPD
Mb2958|M.bovis_AF2122/97 DLAGGQDARQGPSSNSALVVPVRFAGVHVYGDITRGVRAVGSLAAAG--D
Rv2933|M.tuberculosis_H37Rv DLAGGQDARQGPSSNSALVVPVRFAGVHVYGDITRGVRAVGSLAAAG--D
MLBr_02355|M.leprae_Br4923 DLAGG------PTARKTLVLPVRFAGVHVYGDVTRGVCAVGLLTATEGLD
MAV_2370|M.avium_104 ALGDG-----------ALGLVLGIRRLRAYGAARNAHYCYTRVTKADT-S
TH_4621|M.thermoresistible__bu GAGSG-----------LL-LPLGVRRLQAFGPTRGARYCYARVTDADG-S
MSMEG_4727|M.smegmatis_MC2_155 NIASG-----------ML-LPLGVRRLRAYGSTRNVRYCLSRIVKADS-F
MAB_3148c|M.abscessus_ATCC_199 EASKD-----------ALPLPKGVRSLHAYESARATQYCYTRVTKVVG-N
Mflv_3392|M.gilvum_PYR-GCK GGLVD---------------------------------------------
Mvan_3125|M.vanbaalenii_PYR-1 GGIID---------------------------------------------
MMAR_1774|M.marinum_M RLVGRVTLVDPDGQPLLVIDEVEMAVLGSSAS--PTELTSRLFTLEWEPK
MUL_2017|M.ulcerans_Agy99 RLVGRVTLVDPDGQPLLVIDEVEMAVLGSSAS--PTELTSRLFTLEWEPK
Mb2958|M.bovis_AF2122/97 RLVGEVVLTDANGQPLLVVDEVEMAVLGSGSG--ATELTNRLFMLEWEPA
Rv2933|M.tuberculosis_H37Rv RLVGEVVLTDANGQPLLVVDEVEMAVLGSGSG--ATELTNRLFMLEWEPA
MLBr_02355|M.leprae_Br4923 RLVGEVVLTDLDGQPLLVIDEVQMTVLGAGSD--ATELTDRLFTLEWEPT
MAV_2370|M.avium_104 GVEADIDVLDEHGAVLLAVQGLRVGTSASESGTRDRVLTERLLNIEWRQR
TH_4621|M.thermoresistible__bu KAEADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDRVLGERLLTIEWQRR
MSMEG_4727|M.smegmatis_MC2_155 GVEADLELLDADGTVLLSAMGLQLGTGNSDKAEEERLLDERLLTIEWQQR
MAB_3148c|M.abscessus_ATCC_199 EVEADIDLLDETGSVLIAVRGFRFGTGSSDDEQRDQLLNNRLLAIEWQQQ
Mflv_3392|M.gilvum_PYR-GCK --VDESLPAELLAHYLRAEAAVVDGSGAADRDDQAVYRAGERRVPRLEPT
Mvan_3125|M.vanbaalenii_PYR-1 --VDETLPPELLAQYLRAEASALPATG-ADRDDQAVYRGAERRVPRLEPR
: . * : . . .
MMAR_1774|M.marinum_M PLDQTA----ATPGAVLLIGDL-GADDRLLPALQTSLTGSVAE-----LD
MUL_2017|M.ulcerans_Agy99 PLDQTA----ATPGAVLLIGDL-GADDRLLPALQTSLTGSAAE-----LD
Mb2958|M.bovis_AF2122/97 PLEKTA----EATGALLLIGDP-AAGDPLLPALQSSLRDRITD-----LE
Rv2933|M.tuberculosis_H37Rv PLEKTA----EATGALLLIGDP-AAGDPLLPALQSSLRDRITD-----LE
MLBr_02355|M.leprae_Br4923 PLYKEVS-RSSAQGGLLLIGDV-AAGDPLLLALQSSLRARLSENGPPPVD
MAV_2370|M.avium_104 ELPEP---EHADAASWLLIGTT-ATADVLASTLADTLKNHGAQCTTMAWP
TH_4621|M.thermoresistible__bu DLPEA---DSA-AGKWLLVSTS-ATADVSATRLSDALKQAGAESTSMCWP
MSMEG_4727|M.smegmatis_MC2_155 ELPRPEGSETVDAGSWLVILAGDDDENPRAAGVVSALIGAGMPTTTMAWS
MAB_3148c|M.abscessus_ATCC_199 RLPES---VSGAPRRWLLVSTG-ESVDPWAAELIDSLKVRESEVSLIQWR
Mflv_3392|M.gilvum_PYR-GCK PLPAVPLTRLESGTSHLVIGAT----GNVGPYLIRQLADMGAS-------
Mvan_3125|M.vanbaalenii_PYR-1 PLPAVPLTRLESGTSHLVIGAT----GNVGPHLIRQLADMGAA-------
* *:: . : *
MMAR_1774|M.marinum_M VVSPADAAKLRAAITRTDARWQDIVVVCPP--RAVDEALPQDAQLDLTQQ
MUL_2017|M.ulcerans_Agy99 VVSPADAAKLRAAITRTDARWQDIVVVCPP--RAVDEALPQDAQLDLTQQ
Mb2958|M.bovis_AF2122/97 LASAADEATLRAAISRT--SWDGIVVVCPP--RANDESMPDEAQLELART
Rv2933|M.tuberculosis_H37Rv LASAADEATLRAAISRT--SWDGIVVVCPP--RANDESMPDEAQLELART
MLBr_02355|M.leprae_Br4923 CVSFSDEVKLQAAITRTDISWDGIVVVCPP--RASDESLPDDAQLELAQT
MAV_2370|M.avium_104 QQADHTAHAEQLRNQWRGDGFTGVVVLTGP-KNGDNDQ----ESALLSRD
TH_4621|M.thermoresistible__bu QQADHADNVDRFR-AGIADGVTGVVVLTGP-KNGNPDD----AAARRGSD
MSMEG_4727|M.smegmatis_MC2_155 HDADHDAQAAALTARLDEQPLAGVAVIVGD-SETGTDAHDVGADARRGAD
MAB_3148c|M.abscessus_ATCC_199 PNTDRVAALKLLYDQLESGTFDGVLVVTAPGSEGGADR-----VVLQGAD
Mflv_3392|M.gilvum_PYR-GCK ----------------------TIVAAS--------------------RR
Mvan_3125|M.vanbaalenii_PYR-1 ----------------------TVVAVS--------------------RR
: .
MMAR_1774|M.marinum_M RTLMIADVAQTVTRMGARNSPRLWIVTRGAQQLSPADEVTLAQTQLRGIA
MUL_2017|M.ulcerans_Agy99 RTLMIADVAQTVTRMGARNSPRLWIVTRGAQQLSPADEVTLAQTQLRGIA
Mb2958|M.bovis_AF2122/97 RTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIA
Rv2933|M.tuberculosis_H37Rv RTLLVASVVETVTRMGARKSPRLWIVTRGAAQFDAGESVTLAQTGLRGIA
MLBr_02355|M.leprae_Br4923 RTLQIAGVVQAVTQMGARKSPRLWIVTRGAQQLNAGESVTLAQTELRGIV
MAV_2370|M.avium_104 HVQHLVRIARELTDLPG-EPPRLYVVTRNAQTVLPNDVPNLGQAGLRGLV
TH_4621|M.thermoresistible__bu YVRHLVRITRELAEIDG-DAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLL
MSMEG_4727|M.smegmatis_MC2_155 HVRHLVRIARTLADAVG-EPPRLYVVTHRSQHVLDTDEPYLEHSGLRGLI
MAB_3148c|M.abscessus_ATCC_199 QVRHLVRITRELVDLPG-EPPRLFVVTRNAQTVVDGDITNLEQAGLRGLV
Mflv_3392|M.gilvum_PYR-GCK GGSQLSDLTAELAERGT--------------TLVEVAADAADESSMAAVF
Mvan_3125|M.vanbaalenii_PYR-1 GGSQLSELAEELAAGGT--------------TLVEVAADAADEASMAAVF
: :. :. . .: : .:
MMAR_1774|M.marinum_M RVLTFEHPELKTTLVDIEGDGEGSLTALTQELLAGADDDEISLRDGQRFV
MUL_2017|M.ulcerans_Agy99 RVLIFEHPELKTTLVDIEGDGEGSLAALTQELLAGADDDEISLRDGQRFV
Mb2958|M.bovis_AF2122/97 RVLTFEHSELNTTLVDIEPDGTGSLAALAEELLAGSEADEVALRDGQRYV
Rv2933|M.tuberculosis_H37Rv RVLTFEHSELNTTLVDIEPDGTGSLAALAEELLAGSEADEVALRDGQRYV
MLBr_02355|M.leprae_Br4923 RVLTFEHSELKATLLDIEADGTDSLDDLTEELLAGSNHDEVAYRDGQRYV
MAV_2370|M.avium_104 RVIGMEHPQLGAGQIDVDES--TDAQALARQLLAGSEEDETAWRDGAWYT
TH_4621|M.thermoresistible__bu RVIGAEHPHLRTTQIDIADD--ADLDRVAVQLLGGGAEDETAWRDGQWYT
MSMEG_4727|M.smegmatis_MC2_155 RVVGMEHPRLRATQIDVDDS--TAHEALVRQLLSGSPEDETAWRDGQWYA
MAB_3148c|M.abscessus_ATCC_199 RVIGAEYPHLRVTHIDVDRH--TAAQNVAGELVSGSEEDETAWREDHWYR
Mflv_3392|M.gilvum_PYR-GCK DRFGKDLPPLDGIYLASLAG--------GEALLTEMTDEDLSP----MFR
Mvan_3125|M.vanbaalenii_PYR-1 DRFGADLPALEGVYLASLAG--------GEALLADMTDDDLAP----MFR
. : . * : *: :: : :
MMAR_1774|M.marinum_M HRLVAAPTVGTGDLELESRRTVVNLDAGG----AVQLRTDQPGRLDSLTV
MUL_2017|M.ulcerans_Agy99 HRLVAAPTVGTGDLELESRRTVVNLDAGG----AVQLRTDQPGRLDSLTV
Mb2958|M.bovis_AF2122/97 NRLVPAPTTTSGDLAAEARHQVVNLDSSGASRAAVRLQIDQPGRLDALNV
Rv2933|M.tuberculosis_H37Rv NRLVPAPTTTSGDLAAEARHQVVNLDSSGASRAAVRLQIDQPGRLDALNV
MLBr_02355|M.leprae_Br4923 NRLVPAPITPKGELAGETRRKVVELGGLG----AVQLQIDQPGRLDALTV
MAV_2370|M.avium_104 ARLCPAPLLPE-----ERHTAVANHECDG-----MRLQIRTPGDLESLEL
TH_4621|M.thermoresistible__bu ARLSLSPLRPE-----ERKQAVVDCERDG-----MRLEIRTPGDLETMEL
MSMEG_4727|M.smegmatis_MC2_155 ARLCPSPLRAA-----ERRTAVADNASEG-----MRLVVRNPGDLESMEL
MAB_3148c|M.abscessus_ATCC_199 ARLNLGPLGPD-----DWRSTVATPNNEG-----VRFEVRTPGDLQSLGF
Mflv_3392|M.gilvum_PYR-GCK AKVDAAAVLHK-------------------------LSLRTP----VRRF
Mvan_3125|M.vanbaalenii_PYR-1 SKIDTATVLHK-------------------------LSLRTP----VRRF
:: .. : * .
MMAR_1774|M.marinum_M HQVKRCRPQGDQVEVRVAAAGLNFSDVLKAMGVYPGLDGAAPVIGGECVG
MUL_2017|M.ulcerans_Agy99 HQVKRCRPQGDQVEVRVAAAGLNFSDVLKAMGVYPGLDGAAPVIGGECVG
Mb2958|M.bovis_AF2122/97 HEVKRGRPQGDQVEVRVVAAGLNFSDVLKAMGVYPGLDGAAPVIGGECVG
Rv2933|M.tuberculosis_H37Rv HEVKRGRPQGDQVEVRVVAAGLNFSDVLKAMGVYPGLDGAAPVIGGECVG
MLBr_02355|M.leprae_Br4923 HQVKRGEPEGDQVEVRVVAAGLNFSDVLKAMGVYPGLDGGAPAIGGECVG
MAV_2370|M.avium_104 VACDRIPPGPGQIEVAVSASSINFADVLVAFGRYPAFEGRLPELGTDFAG
TH_4621|M.thermoresistible__bu AAFDRVPPGPGQIEVAVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAG
MSMEG_4727|M.smegmatis_MC2_155 VTFERGTPGPGQIEVAVKASSINFADVLVAFGRCPSFDGRLPELGSEFGG
MAB_3148c|M.abscessus_ATCC_199 VAFDRVAPGPGQIEVSVTATSINFADVLNVYGRYSSFEGRQ-ELGVDFAG
Mflv_3392|M.gilvum_PYR-GCK VLFSSITGLLGSRAVAHYTAANAFADAFAYARRTLGLPATVVDWG-----
Mvan_3125|M.vanbaalenii_PYR-1 VLFSSITGLLGSRAVAHYTAANAFADAFAYARRALGLPATVLDWG-----
. .. * ::. *:*.: : . *
MMAR_1774|M.marinum_M YVTAIGDDVDSLEIGQRVIAFGP-GTFGSHLGTIADLVVPIPDTLPDNEA
MUL_2017|M.ulcerans_Agy99 YVTAIGDDVDSLEIGQRVIAFGP-GTFGSHLGTIADLVVPIPDTLPDNEA
Mb2958|M.bovis_AF2122/97 YVTAIGDEVDGVEVGQRVIAFGP-GTFGTHLGTIADLVVPIPDTLADNEA
Rv2933|M.tuberculosis_H37Rv YVTAIGDEVDGVEVGQRVIAFGP-GTFGTHLGTIADLVVPIPDTLADNEA
MLBr_02355|M.leprae_Br4923 YVTAIGDDVDSVEVGQRVIAFGP-GTFGTYVGTIADLVVPIPDTLSDHEA
MAV_2370|M.avium_104 VVTAVGPDVTDHKVGDHVGGLSANGCWGTFLTCDARLAVTLPPGLADDQA
TH_4621|M.thermoresistible__bu VVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQA
MSMEG_4727|M.smegmatis_MC2_155 VVTAVGPGVTTHRVGDRVGGVSANGCWSNFVTCEADLATKLPEGISEHEA
MAB_3148c|M.abscessus_ATCC_199 VVTAVGEGVTQHQVGDRVGGMTPTGAWRSFVVVDANLAATLPAEVPDREA
Mflv_3392|M.gilvum_PYR-GCK ----LWKSWADAQPQMKAAGLEP---------MPNDVAIRMLPAVLSPDA
Mvan_3125|M.vanbaalenii_PYR-1 ----LWKSWSDAQPQMKAAGLEP---------MPNDVAIKMLPAVLGPDA
: . :. .. . :. : : :*
MMAR_1774|M.marinum_M ATFGIAYLTAWHSLCEVGRLSPGERVLIHSATGGVGMAAVSIAKMIGARI
MUL_2017|M.ulcerans_Agy99 ATFGIAYLTAWHSLCEVGRLSPGERVLIHSATGGVGMAAVSIAKMIGARI
Mb2958|M.bovis_AF2122/97 ATFGVAYLTAWHSLCEVGRLSPGERVLIHSATGGVGMAAVSIAKMIGARI
Rv2933|M.tuberculosis_H37Rv ATFGVAYLTAWHSLCEVGRLSPGERVLIHSATGGVGMAAVSIAKMIGARI
MLBr_02355|M.leprae_Br4923 ATFGVAYLTAWHCLCEVGRLSPGERVLIHSATGGVGMAAVSIAKMLGARI
MAV_2370|M.avium_104 AAVTTAHATAYYGLHELARIGAGDRVLIHSATGGVGQAAIAIARAAGAEI
TH_4621|M.thermoresistible__bu AAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGVGLAAIAIARSVGAQI
MSMEG_4727|M.smegmatis_MC2_155 AAVGLAYGTVWLGLTELARMSAGDKILIHSATGGVGQAAIAVARAAGAEI
MAB_3148c|M.abscessus_ATCC_199 AAVPGAHVTAWYGLHELARISAGDKVLIHSGTGGVGQAAIAIARAAGAEI
Mflv_3392|M.gilvum_PYR-GCK AVQTIVAGADWGRLADAYRMRAAVKVLDHLVNAPDASADLDSVAPP----
Mvan_3125|M.vanbaalenii_PYR-1 PVQAVVAGADWPRLADAYRMRAAVKVLDHLVSGPGEDADLGAVPAP----
.. . : : * : *: .. ::* * .. * : .
MMAR_1774|M.marinum_M YTTAGSDAKREMLSSLGVDYVGDSRTVDFADEILELTDGYGVDIVLNSLA
MUL_2017|M.ulcerans_Agy99 YTTAGSDAKREMLSSLGVDYVGDSRTVDFADEILELTDGYGVDIVLNSLA
Mb2958|M.bovis_AF2122/97 YTTAGSDAKREMLSRLGVEYVGDSRSVDFADEILELTDGYGVDVVLNSLA
Rv2933|M.tuberculosis_H37Rv YTTAGSDAKREMLSRLGVEYVGDSRSVDFADEILELTDGYGVDVVLNSLA
MLBr_02355|M.leprae_Br4923 YTTAGSDAKRQMLSELGVEYVGDSRSVDFADEILELTHGYGVDIILNSLA
MAV_2370|M.avium_104 FATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIRHDTDGYGVDIVLNSVT
TH_4621|M.thermoresistible__bu YATAGSPARRDLLRDMGIEHVYDSRSTAFADEIRRDTDGYGVDVVLNSLP
MSMEG_4727|M.smegmatis_MC2_155 YATAGSEKRRQLLRDWGIEHVYDSRTTAFADQIRTDTDGYGVDIVLNSVT
MAB_3148c|M.abscessus_ATCC_199 YATAGSPERRDLLRSWGIKHVYDSRSTDFAELIRRDTDGYGVDIVLNSLT
Mflv_3392|M.gilvum_PYR-GCK ---AWGTVLGEAVTGSPHERLWRARLTPGERPYPVAHRVRGVEVVPVSVL
Mvan_3125|M.vanbaalenii_PYR-1 ---AWGTVLGEPVSGTSHDHLWRARVLPGERSYPVAHRVRGVEVVPVSVL
* . : : . : :* **::: *:
MMAR_1774|M.marinum_M GEAIQRGVQILAPGGRFIELGKKDVHANANLGLAALAKSASFSVVDLDLN
MUL_2017|M.ulcerans_Agy99 GEAIQRGVQILAPGGRFIELGKKDVHANANLGLAALAKSASFSVVDLDLN
Mb2958|M.bovis_AF2122/97 GEAIQRGVQILAPGGRFIELGKKDVYADASLGLAALAKSASFSVVDLDLN
Rv2933|M.tuberculosis_H37Rv GEAIQRGVQILAPGGRFIELGKKDVYADASLGLAALAKSASFSVVDLDLN
MLBr_02355|M.leprae_Br4923 DKAIQRGVQILAPGGRFIEIGKKDVYDDANLGLAALAKSASFSVVDLDLN
MAV_2370|M.avium_104 GAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLLPFRRNLTFYALDLALM
TH_4621|M.thermoresistible__bu GAAQRAGLELLSFGGRFIEIGKRDIYGDTRLGLFPFRRNLAFHGVDLGLM
MSMEG_4727|M.smegmatis_MC2_155 GPAQRAGLELLAFGGRFVEIGKRDIYADTRLGLFPFRRNLSFYAVDLALM
MAB_3148c|M.abscessus_ATCC_199 GAAQRAGVELLTFGGRFIEIGKRDIYGDTRLGLFPFRRNLSFHAVDLVLV
Mflv_3392|M.gilvum_PYR-GCK LQTLSAAAGQLDGA----------AIGDVRFEYPIVAD------------
Mvan_3125|M.vanbaalenii_PYR-1 LQTLSAAAAQLDEAG--PNDGPTVAVGDVRFEYPIVAD------------
: . * . :. : .
MMAR_1774|M.marinum_M LKLQPAKYRELLQEILEHVADGALEVLPVTEFGLRDAADGFRLMASGKHT
MUL_2017|M.ulcerans_Agy99 LKLQPAKYRELLQEILEHVADGTLEVLPVTEFGLRDAADGFRLMASGKHT
Mb2958|M.bovis_AF2122/97 LKLQPARYRQLLQHILQHVADGKLEVLPVTAFSLHDAADAFRLMASGKHT
Rv2933|M.tuberculosis_H37Rv LKLQPARYRQLLQHILQHVADGKLEVLPVTAFSLHDAADAFRLMASGKHT
MLBr_02355|M.leprae_Br4923 LKLHPARYRQLLQHILAHVADGRLPVLPVTEFSLHNAADAFRLMASGKHT
MAV_2370|M.avium_104 SFSHPDRLRGLLRTVYRLTADGALPMPESTHYPLADAASAIRVMSAAQHT
TH_4621|M.thermoresistible__bu ADSHPHKIRELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHV
MSMEG_4727|M.smegmatis_MC2_155 TVTHPQKIRDLLATVYRLIADGTLPLPEITHYPLEEAATAIRIMGGAQHT
MAB_3148c|M.abscessus_ATCC_199 AKTRPEAIYRTLTALYGQMAEGVLPLPEISPSPLQEAAESIRVMGAAGHT
Mflv_3392|M.gilvum_PYR-GCK -----------APKVIHVVFDKGGDSGALSVWSSSAPDTPE--QRWTRHA
Mvan_3125|M.vanbaalenii_PYR-1 -----------QPKVVHVVADG----KALTVWSSSGPDSPE--QRWTRHA
: : : . *.
MMAR_1774|M.marinum_M GKIVISIPDGGTVEAIASPPPEPLVSPEGGYLIVGGMGGLGFVVARWLAE
MUL_2017|M.ulcerans_Agy99 GKIVISIPDGSTVETIASPPPEPLVSPEGGYLIVGGMGGLGFVVARWLAE
Mb2958|M.bovis_AF2122/97 GKIVISIPQHGSIEAIAAPPPLPLVSRDGGYLIVGGMGGLGFVVARWLAE
Rv2933|M.tuberculosis_H37Rv GKIVISIPQHGSIEAIAAPPPLPLVSRDGGYLIVGGMGGLGFVVARWLAE
MLBr_02355|M.leprae_Br4923 GKIVISIPYEGNIEAIASPPPVPLVSQDGGYLVVGGMGGLGFVFARWLAE
MAV_2370|M.avium_104 GKLVLDVPHAGRSRVVVPPAQVRAFRSDGAYIVTGGLGGLGLFLAEKMAS
TH_4621|M.thermoresistible__bu GKLVLDVPHTGRADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAA
MSMEG_4727|M.smegmatis_MC2_155 GKLVIDIPDTGQSQVVVPPEQVPVFRGDGAYVITGGLGGLGLFLAERMAA
MAB_3148c|M.abscessus_ATCC_199 GKLVLDLPKAGEVSAVIPPSHAPAFRRDGAYVVTGGLGGLGLFLARKLAA
Mflv_3392|M.gilvum_PYR-GCK GAQLSDAPSAALSGDQSPGDR--VFDSAAIAEMQSALGVQGQPFDWTVSD
Mvan_3125|M.vanbaalenii_PYR-1 SAELTTAPGGTPAGDQGAVGK--TFDGASIAEMQRALGVEGQPFEWAVSD
. : * . . . : .:* * . ::
MMAR_1774|M.marinum_M QG----AGLIVLNGRSEPSDDVRAAIADLSSGGTRIEVVTGDIAEPGTAE
MUL_2017|M.ulcerans_Agy99 QG----AGLIVLNGRSEPSDDVRAAIADLSSGGTRIEVVTGDIAEPGTAE
Mb2958|M.bovis_AF2122/97 QG----AGLIVLNGRSAPSDEVAAAIAELNASGSRIEVITGDITEPDTAE
Rv2933|M.tuberculosis_H37Rv QG----AGLIVLNGRSAPSDEVAAAIAELNASGSRIEVITGDITEPDTAE
MLBr_02355|M.leprae_Br4923 QG----AGLIVLNGRSSPSDDVTAAIADLTAAGHRIEVVTGDISEPGTAD
MAV_2370|M.avium_104 PGSRAGCGRIVLCSRALPNPKALATLERIRQMGADIVVERGDIAEAGTAQ
TH_4621|M.thermoresistible__bu AG--AGC--IVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXXRG----
MSMEG_4727|M.smegmatis_MC2_155 AG----CGRIVVNSRSAPSTRSSEIIELIRATGADIVVECGDIAEPDTAL
MAB_3148c|M.abscessus_ATCC_199 AG----VGRIILNGRSAPKPEALAAIEQIRQGGTEIDVALGDIAEPDTAQ
Mflv_3392|M.gilvum_PYR-GCK CT--------TTAAGARADITLPDTTESPAAALVDVAVHVARLADAGNAQ
Mvan_3125|M.vanbaalenii_PYR-1 CA--------ATAAGARADVEVPEATESPAAALVDAAVHVARLADADNAQ
. : .. * .
MMAR_1774|M.marinum_M RLVQTVQNSGFRLAGVLHSAMVLDDEIVLNMSESAARR-VFTPKVAGSWR
MUL_2017|M.ulcerans_Agy99 RLVQTVQNSGFRLAGVLHSAMVLDDEIVLNMSESAARR-VFTPKVAGSWR
Mb2958|M.bovis_AF2122/97 RLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAARR-VFAPKVTGSWR
Rv2933|M.tuberculosis_H37Rv RLVRAVEDAGFRLAGVVHSAMVLADEIVLNMTDSAARR-VFAPKVTGSWR
MLBr_02355|M.leprae_Br4923 RLVHAVQSAGFRLAGVLHSAMVLADEIMLNMTDSAARR-VFVPKVTGSWR
MAV_2370|M.avium_104 RLLDVATATGLPVRGVLHLAAVIEDATLANITDELIER-DWAAKVYGAWN
TH_4621|M.thermoresistible__bu QPVEVAVPT------ELRHADEHPDRRGAQLCDEFARG-EQGAQR----N
MSMEG_4727|M.smegmatis_MC2_155 RLVAAATQTGLPLRGVLHAAAVVEDATLANITDELVEH-DWAPKVYGAWN
MAB_3148c|M.abscessus_ATCC_199 RLVAAATETGKPVRGVLHAAALVHDATLANITDELIDRGDWRPKVHGAWN
Mflv_3392|M.gilvum_PYR-GCK LLLPAGAET-LAVTASPGTAGVVEAYRRPDAGGDTLVVDVLVKGHDGTIW
Mvan_3125|M.vanbaalenii_PYR-1 LLLPAGVES-LAVAATVGTSGVIEAYRR-DVEGDALVVDVLVKGADDSVW
: . : : : .
MMAR_1774|M.marinum_M LHEATADLD-----LDWWLTFSSVASLLGAPGQGSYAAANSFVDGLVAYR
MUL_2017|M.ulcerans_Agy99 LHEATADLD-----LDWWLTFSSVASLLGAPGQGSYAAANSFVDGLVAYR
Mb2958|M.bovis_AF2122/97 LHVATAARD-----VDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHR
Rv2933|M.tuberculosis_H37Rv LHVATAARD-----VDWWLTFSSAAALLGTPGQGAYAAANSWVDGLVAHR
MLBr_02355|M.leprae_Br4923 LHQATAAFE-----VDWWLTFSSASSLLGTPGQGAYAAANAWVDGLVAYR
MAV_2370|M.avium_104 LHCALQESG-AEQSLDWFCSFSSAAALVGSPGQGAYAAANSWLDAFTRWR
TH_4621|M.thermoresistible__bu QHRTDAGEG-QRD--------AHPPGAVGHDQPDPGALSDTGLDERGGQF
MSMEG_4727|M.smegmatis_MC2_155 LHQAVQSGGPATSELDWFCAFSSAAALVGSPGQGAYAAANSWLDAFMQWR
MAB_3148c|M.abscessus_ATCC_199 LHEATADQP-----LDWFCSFSSIAALVGSPGQGAYAAANSWLDGFTHWR
Mflv_3392|M.gilvum_PYR-GCK VDIRG-------------LTYAPVESAPAPVVEENASAATEFVD-WAAMN
Mvan_3125|M.vanbaalenii_PYR-1 VDIRG-------------LNYAPVESAPAPVADESASGATEFVD-WSTMT
. : . . : : :*
MMAR_1774|M.marinum_M RSLGLPAVGINWGPWAEVGRAQFFADLGVSMITVEQGLAAMQLVLSADRA
MUL_2017|M.ulcerans_Agy99 RSLGLPAVGINWGPWAEVGRAQFFADLGVSMITVEQGLAAMQLVLSADRA
Mb2958|M.bovis_AF2122/97 RSAGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRG
Rv2933|M.tuberculosis_H37Rv RSAGLPAVGINWGPWADVGRAQFFKDLGVEMINAEQGLAAMQAVLTADRG
MLBr_02355|M.leprae_Br4923 RSLGLPAVGINWGPWAEVGRAQFFAGLGVSLLTAEQGLAAMQTVLAADRA
MAV_2370|M.avium_104 RARGLKATAIAWGAWAQIGRGAALADSADVAITPDEGAYAFEALLRHDRA
TH_4621|M.thermoresistible__bu PGVGVQIPVADPGVGIDH-RGAVRVDSGVPAQQGVDGEVVRHRTLSSVRS
MSMEG_4727|M.smegmatis_MC2_155 RAQGLPATSIAWGAWGEIGRGTAMAE-GDNAIAPDEGAYAFEAILRHDRV
MAB_3148c|M.abscessus_ATCC_199 RAQGLPATVIAWGAWSEIGQGTHLAQNAEAAILPDEGAYAFDTVLRHNRA
Mflv_3392|M.gilvum_PYR-GCK RQQTVAELRTRLRGILARELGMPEDAVDVEMPFPELGLDSMMAMNLLRDA
Mvan_3125|M.vanbaalenii_PYR-1 RQQTVAELRTRLRTILGRELGMPDNAVDFDMPFPELGLDSMMAMNLLRDA
: . *
MMAR_1774|M.marinum_M RTGVFILDARQWFQSFPAAAGSSLFSKLQESTTP---ERRAGGAIRAELD
MUL_2017|M.ulcerans_Agy99 RTGVFILDARQWFQSFPAAAGSSLFSKLQESTTP---ERRAGGAIRAELD
Mb2958|M.bovis_AF2122/97 RTGVFSLDARQWFQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLD
Rv2933|M.tuberculosis_H37Rv RTGVFSLDARQWFQSFPAVAGSSLFAKLHDSAARKSGQRRGGGAIRAQLD
MLBr_02355|M.leprae_Br4923 QTGVFSLDARQWFQSFPAVAGSSLFANLRDTATLKSGERRGVGKIRAQLD
MAV_2370|M.avium_104 CTGYAPITGTPWLTAF---AQRSPFAEAFRANGQ---SATGTSKLRAELE
TH_4621|M.thermoresistible__bu GR-------SSRWTAP---GSR--CGSGRRYGGE---SCRRTTGPAAGAA
MSMEG_4727|M.smegmatis_MC2_155 YNGYAPVLGASWLTAF---AQRSPFAELFLADTQ---GASETRKLRSELA
MAB_3148c|M.abscessus_ATCC_199 YTAYAPMAGISWLADF---VERSPFAQAFRDAGQ---NQTETNKFLDELR
Mflv_3392|M.gilvum_PYR-GCK KALVRIDLSATMLWNNPSIAAMSEFVADLLAPGQ---QPADDEAPEIGEG
Mvan_3125|M.vanbaalenii_PYR-1 KALVRTDLSATMLWNHPSISQMSEFVADLLAPQQ---NAVDEPEPESNEN
MMAR_1774|M.marinum_M ALEGAAAAERPARLAAAIAGEIRAVLRSTEPIDVDRPMESLGLDSLMALE
MUL_2017|M.ulcerans_Agy99 ALERAAAAELPARLAGAIAGEIRAVLRSTEPIDVDRPMESLGLDSLMALE
Mb2958|M.bovis_AF2122/97 ALD---AAERPGHLASAIADEIRAVLRSGDPIDHHRPLETLGLDSLMGLE
Rv2933|M.tuberculosis_H37Rv ALD---AAERPGHLASAIADEIRAVLRSGDPIDHHRPLETLGLDSLMGLE
MLBr_02355|M.leprae_Br4923 VLD---AAERPGHLASAIADEIRAVLRSSDPIDHDRPLEALGLDSLMGLE
MAV_2370|M.avium_104 ELP---PEEWSTRLRRLISDQVSLILRRNV--DPDRPLPEYGLDSLGGLE
TH_4621|M.thermoresistible__bu ARR---GR-----------------TRRRR--RPRRPPPPP---------
MSMEG_4727|M.smegmatis_MC2_155 ALP---REEWPTHLRRLIAEQVGLLLRRTV--DPDRPLSEYGLDSLGHLE
MAB_3148c|M.abscessus_ATCC_199 ALP---REEWPTRLRKLVAEQVGLVLRRSI--DPDRSLPDYGLDSLGNLE
Mflv_3392|M.gilvum_PYR-GCK GEP-----------------------------DDDDDSFGLLDELFDSIE
Mvan_3125|M.vanbaalenii_PYR-1 AE-------------------------------DDSDSFSVLDELFS---
MMAR_1774|M.marinum_M LRNRLEASLGTTLPAALVWAYPTITDLAGALCERLGYAQLADVEQTPDAE
MUL_2017|M.ulcerans_Agy99 LRNRLEASLGTTLPAALVWAYPTITDLAGALCERLGYAQLADVEQTPDAE
Mb2958|M.bovis_AF2122/97 LRNRLEASLGITLPVALVWAYPTISDLATALCERMDYATPAAAQEISDTE
Rv2933|M.tuberculosis_H37Rv LRNRLEASLGITLPVALVWAYPTISDLATALCERMDYATPAAAQEISDTE
MLBr_02355|M.leprae_Br4923 LRNRLEASLGITLPVALVWAYPTTADLAAALCERMDYALPAEVQEATDTN
MAV_2370|M.avium_104 LLTRIQTETGIRVSPADIAAIGTIRGLADLLRDKLTPAGAAQAERV----
TH_4621|M.thermoresistible__bu --DRVRHRAGP--------AHGPVRR------------------------
MSMEG_4727|M.smegmatis_MC2_155 LRTRIETETGVRVS---AMDMTTIRGLAQRLCEMLDTDDAVSAPS-----
MAB_3148c|M.abscessus_ATCC_199 IRTRIQADTGVRIG---PADVSTVRSLAAHIYDRLAEQESEVASS-----
Mflv_3392|M.gilvum_PYR-GCK SDSVESAGAGSEGAN-----------------------------------
Mvan_3125|M.vanbaalenii_PYR-1 --SVESANAGSEGSI-----------------------------------
*
MMAR_1774|M.marinum_M AALSDEEMELLSDLVAASELETATGSSE
MUL_2017|M.ulcerans_Agy99 AALSDEEMELLSDLVAARELETATGSSE
Mb2958|M.bovis_AF2122/97 PELSDEEMDLLADLVDASELEAATRGES
Rv2933|M.tuberculosis_H37Rv PELSDEEMDLLADLVDASELEAATRGES
MLBr_02355|M.leprae_Br4923 AELSKAEMDLLSDLVEASELEAATRGES
MAV_2370|M.avium_104 ----------------------------
TH_4621|M.thermoresistible__bu ----------------------------
MSMEG_4727|M.smegmatis_MC2_155 ----------------------------
MAB_3148c|M.abscessus_ATCC_199 ----------------------------
Mflv_3392|M.gilvum_PYR-GCK ----------------------------
Mvan_3125|M.vanbaalenii_PYR-1 ----------------------------