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VLSIPPVDLIEAAADPASRRRQFELLDAAFSEVGYVHVVGHRIPSSVFTELYAVTRRFFGLPAEEKSKVA QPTPEQVRGWSGAGSEGMAYSLGEETHADLKEKMDIGPVTGPTIGQPGAGPMAYPNLWPELPEFRTAWEC YYQHMQRVGAELLALAAEGFGLSRQHFVPLFDAELSMLRALHFPPQPEPPLPHQFRAGIHTDYGAFTVVS AESTPGGLQVLEADGEWLEVNTTPATLVVLVGDLLAEWTGNHWPATLHRTANPPRSVAFENSRLAFAFYQ HPNWDVEVAELSPFAGGAAHATDDALVSGKHLAEKYVRQTTFGTSDPTV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4007 | - | - | 100% (329) | oxidoreductase, 2OG-Fe(II) oxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_4008 | - | 2e-59 | 37.58% (306) | oxidoreductase, 2OG-Fe(II) oxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_4685 | - | 2e-41 | 34.55% (301) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2580 | - | 5e-40 | 36.23% (276) | 2OG-Fe(II) oxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4434c | - | 2e-20 | 28.78% (271) | putative iron/ascorbate dependent oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4913 | - | 5e-21 | 29.51% (305) | oxidoreductase, 2OG-Fe(II) oxygenase family protein |
| M. thermoresistible (build 8) | TH_4524 | - | 5e-32 | 32.71% (321) | PUTATIVE 2OG-Fe(II) oxygenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4054 | - | 4e-37 | 33.78% (296) | 2OG-Fe(II) oxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2580|M.gilvum_PYR-GCK -----------MSVIATVDLSRWREG-GPAAEDVAAQVDAGLQRAGFILV
Mvan_4054|M.vanbaalenii_PYR-1 -----------MSVIATVDLSRWRAG-GAAADAVAADVDEGLQRAGFILV
MSMEG_4007|M.smegmatis_MC2_155 -----------MLSIPPVDLIEAAAD-PASRRRQFELLDAAFSEVGYVHV
MAB_4434c|M.abscessus_ATCC_199 MAVKTVAPKRLASNHGRVAELPVIDL-SSDSNQLRAALREVAHEVGFFYL
MAV_4913|M.avium_104 ------MSNDMCPVPG-VTAVPGVDL-RADPDVLRDGLREAAHRVGFFYL
TH_4524|M.thermoresistible__bu -------MAGDFTSVPVIDISALRHGSGPGYRRAVTALGDAARHVGFAQL
: . : ..*: :
Mflv_2580|M.gilvum_PYR-GCK TGHGVDPDLARDVRAAAREFFALDPTVKA--GYSVPVGGRGWIGPGAEAN
Mvan_4054|M.vanbaalenii_PYR-1 SGHGVSASLARDVRAAAREFFALPDEVKS--GYSVPVGGHGWIGPGAEAN
MSMEG_4007|M.smegmatis_MC2_155 VGHRIPSSVFTELYAVTRRFFGLPAEEKSKVAQPTPEQVRGWSGAGSEGM
MAB_4434c|M.abscessus_ATCC_199 TGHGVSPQLVHEVLSAARKLFALSEADKEAIAMVRSPHFRGFTRLGGE--
MAV_4913|M.avium_104 TGHGVPADLVDRVLDAARRFFRLPQADKDAVAMVRSPHFRGYTRLGGE--
TH_4524|M.thermoresistible__bu VGHGIDPALFDALVDRTRAFFALPAAEKHRVYIGNSTNHRGYVPPGEE--
** : . : : :* :* * * . :*: * *
Mflv_2580|M.gilvum_PYR-GCK GYAEGTETPPDLKESFSLGAETATG--DAEVDR-IWFAPNVWPREVPELA
Mvan_4054|M.vanbaalenii_PYR-1 GYAEGTETPPDLKETFSLGAETATG--DAEVDR-IWFAPNVWPREVPALQ
MSMEG_4007|M.smegmatis_MC2_155 AYSLGEETHADLKEKMDIGPVTGPT--IGQPGAGPMAYPNLWP-ELPEFR
MAB_4434c|M.abscessus_ATCC_199 ----LTGGLTDWREQIDVGPERAASPTADGRDYMWLQGPNQWPAAVPELR
MAV_4913|M.avium_104 ----RTRGAVDWREQIDIGPQRPPIGGLDKSDYRWLQGPNQWPAALPELP
TH_4524|M.thermoresistible__bu ---VFAGGTADTKEAFDLSYELPAD-DPRYLAGDPLLGPNQWP-ELTGFR
* :* :.:. . ** ** :. :
Mflv_2580|M.gilvum_PYR-GCK PLVEEYTAQMRRVADDLLALCAHALGLSVNPFAALAS-APTWTMNINHYP
Mvan_4054|M.vanbaalenii_PYR-1 PLLTEYTAQMRGVADDLLALFAHALKLPANPFAELAS-TPTWTMNINHYP
MSMEG_4007|M.smegmatis_MC2_155 TAWECYYQHMQRVGAELLALAAEGFGLSRQHFVPLFD-AELSMLRALHFP
MAB_4434c|M.abscessus_ATCC_199 PALESWDIALAEVGRKLLREWAIALGSDGAVFSEAFGDKPATLIKVIRYP
MAV_4913|M.avium_104 GLIAEWDAALSGVARTLLRHWAAALGSPADVFDAAFADAPATLIKIIRYP
TH_4524|M.thermoresistible__bu EAVTAWYDAVFALSRAILRAFAVALGQPPDRFDRYVT-TPPSQLRLIHYP
: : :. :* * .: * :. ::*
Mflv_2580|M.gilvum_PYR-GCK PVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEQA---GWEN
Mvan_4054|M.vanbaalenii_PYR-1 PVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEDA---GWQD
MSMEG_4007|M.smegmatis_MC2_155 PQPEP--PLPHQFRAGIHTDYGAFTVVSAESTPGGLQVLEADG---EWLE
MAB_4434c|M.abscessus_ATCC_199 S------DGTTSQGVGAHRDSGVLTLLLTEPEVGGLQVEVDG----AWLE
MAV_4913|M.avium_104 G------RAAGPQGVGAHRDAGVLTLLLAEPGSRGLQVRRGGPRGDGWID
TH_4524|M.thermoresistible__bu ADP----SAVDRPGIGAHTDYECFTLLR--PTAPGLEVLNAAG---QWID
* * * .*:: . **:* * :
Mflv_2580|M.gilvum_PYR-GCK APYDPAALTVNIGDLLEYWSGRRWPSGRHR-VLPPQPDAPEEDLVSLIYF
Mvan_4054|M.vanbaalenii_PYR-1 APYDPDALTVNIGDLLEYWSGRRWPSGRHR-VLPPQPGAPEEDLVSLIYF
MSMEG_4007|M.smegmatis_MC2_155 VNTTPATLVVLVGDLLAEWTGNHWPATLHRTANPPRSVAFENSRLAFAFY
MAB_4434c|M.abscessus_ATCC_199 APGREGAFIVNIGELLERASGGYLRATRHR----VTLTG--APRISVAYF
MAV_4913|M.avium_104 VPPRQGAFIVNIGELLEAATRGYLRATEHR----VNLAGSTAERISVPYF
TH_4524|M.thermoresistible__bu VPYLDDAFVLNIGDLLEIWTNGAFVATTHR------VRRVTSERYSFPLF
. :: : :*:** : : ** :. :
Mflv_2580|M.gilvum_PYR-GCK YEANHDALVTPLSPPIG---------------RAEGLEPVLSADFIKQRL
Mvan_4054|M.vanbaalenii_PYR-1 YEANHDALVTPLDPPVG---------------RVSGLAPVTSADFIKERL
MSMEG_4007|M.smegmatis_MC2_155 QHPNWDVEVAELSPFAGGAA------------HATDDALVSGKHLAEKYV
MAB_4434c|M.abscessus_ATCC_199 FNPRLDARIPVLELPPELRDRARG----VSADPDDPIHATYGENAWKSRL
MAV_4913|M.avium_104 FNPRLDARIPVLSLPPELRARAGERWT-PSEDPADPIFSVYGRNAWKSRL
TH_4524|M.thermoresistible__bu VNVDADTEVAPLAEFVDGTARYAPVIAGEHLFAQTARSFRYLQDRIRRGE
. *. :. * . .
Mflv_2580|M.gilvum_PYR-GCK DAITVS---------------
Mvan_4054|M.vanbaalenii_PYR-1 DAITVG---------------
MSMEG_4007|M.smegmatis_MC2_155 RQTTFGTSDPTV---------
MAB_4434c|M.abscessus_ATCC_199 RAHPDVAAVHGHLDS------
MAV_4913|M.avium_104 RSHPDVASAHGFSAHHGAAD-
TH_4524|M.thermoresistible__bu VSLPDGAYPLSAFGRRAASPR
.