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VSVIATVDLSRWREGGPAAEDVAAQVDAGLQRAGFILVTGHGVDPDLARDVRAAAREFFALDPTVKAGYS VPVGGRGWIGPGAEANGYAEGTETPPDLKESFSLGAETATGDAEVDRIWFAPNVWPREVPELAPLVEEYT AQMRRVADDLLALCAHALGLSVNPFAALASAPTWTMNINHYPPVSVVGEPEPGQFRIGPHTDFGTVTILD REPGAGGLQVYSEQAGWENAPYDPAALTVNIGDLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYE ANHDALVTPLSPPIGRAEGLEPVLSADFIKQRLDAITVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2580 | - | - | 100% (319) | 2OG-Fe(II) oxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4434c | - | 3e-26 | 34.83% (267) | putative iron/ascorbate dependent oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4913 | - | 4e-24 | 34.64% (280) | oxidoreductase, 2OG-Fe(II) oxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_4685 | - | 1e-157 | 82.39% (318) | oxidoreductase |
| M. thermoresistible (build 8) | TH_4524 | - | 2e-23 | 29.84% (315) | PUTATIVE 2OG-Fe(II) oxygenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4054 | - | 1e-164 | 87.42% (318) | 2OG-Fe(II) oxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2580|M.gilvum_PYR-GCK -----------MSVIATVDLSRWREGGPAAEDVAAQVDAGLQRAGFILVT
Mvan_4054|M.vanbaalenii_PYR-1 -----------MSVIATVDLSRWRAGGAAADAVAADVDEGLQRAGFILVS
MSMEG_4685|M.smegmatis_MC2_155 -----------MSAIATVDLSRWYAGGAEADAVAAEVDAGLQRAGFIVVT
MAB_4434c|M.abscessus_ATCC_199 MAVKTVAPKRLASNHGRVAELPVIDLSSDSNQLRAALREVAHEVGFFYLT
MAV_4913|M.avium_104 ------MSNDMCPVPG-VTAVPGVDLRADPDVLRDGLREAAHRVGFFYLT
TH_4524|M.thermoresistible__bu ------MAGDFTSVPVIDISALRHGSGPGYRRAVTALGDAARHVGFAQLV
. . : :..** :
Mflv_2580|M.gilvum_PYR-GCK GHGVDPDLARDVRAAAREFFALDPTVKAGYSVPVG--GRGWIGPGAEANG
Mvan_4054|M.vanbaalenii_PYR-1 GHGVSASLARDVRAAAREFFALPDEVKSGYSVPVG--GHGWIGPGAEANG
MSMEG_4685|M.smegmatis_MC2_155 GHGVDPTLAARVRAASREFFALPDEVKQRYSVPVG--GRGWIGPGAEANG
MAB_4434c|M.abscessus_ATCC_199 GHGVSPQLVHEVLSAARKLFALSEADKEAIAMVRSPHFRGFTRLGGEL--
MAV_4913|M.avium_104 GHGVPADLVDRVLDAARRFFRLPQADKDAVAMVRSPHFRGYTRLGGER--
TH_4524|M.thermoresistible__bu GHGIDPALFDALVDRTRAFFALPAAEKHRVYIGNSTNHRGYVPPGEEVF-
***: . * : :* :* * * : . :*: * *
Mflv_2580|M.gilvum_PYR-GCK YAEGTETPPDLKESFSLGAETATG---DAEVDRIWFAPNVWPREVPELAP
Mvan_4054|M.vanbaalenii_PYR-1 YAEGTETPPDLKETFSLGAETATG---DAEVDRIWFAPNVWPREVPALQP
MSMEG_4685|M.smegmatis_MC2_155 YAEGTETPPDLKESFSLGADDATG---DPEVDRIWFAPNVWPDEVPALRS
MAB_4434c|M.abscessus_ATCC_199 ----TGGLTDWREQIDVGPERAASPTADGRDYMWLQGPNQWPAAVPELRP
MAV_4913|M.avium_104 ----TRGAVDWREQIDIGPQRPPIGGLDKSDYRWLQGPNQWPAALPELPG
TH_4524|M.thermoresistible__bu ----AGGTADTKEAFDLSYELPAD-DPRYLAGDPLLGPNQWP-ELTGFRE
: * :* :.:. : .. .** ** :. :
Mflv_2580|M.gilvum_PYR-GCK LVEEYTAQMRRVADDLLALCAHALGLSVNPF-AALASAPTWTMNINHYPP
Mvan_4054|M.vanbaalenii_PYR-1 LLTEYTAQMRGVADDLLALFAHALKLPANPF-AELASTPTWTMNINHYPP
MSMEG_4685|M.smegmatis_MC2_155 LVTEYTAAMRKLSDDLLALFAHALGLPANPF-VALADRPTWTMNINHYPP
MAB_4434c|M.abscessus_ATCC_199 ALESWDIALAEVGRKLLREWAIALGSDGAVFSEAFGDKPATLIKVIRYPS
MAV_4913|M.avium_104 LIAEWDAALSGVARTLLRHWAAALGSPADVFDAAFADAPATLIKIIRYPG
TH_4524|M.thermoresistible__bu AVTAWYDAVFALSRAILRAFAVALGQPPDRF-DRYVTTPPSQLRLIHYPA
: : : :. :* * ** * *. :.: :**
Mflv_2580|M.gilvum_PYR-GCK VSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEQAG---WENA
Mvan_4054|M.vanbaalenii_PYR-1 VSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEDAG---WQDA
MSMEG_4685|M.smegmatis_MC2_155 MTVVGEPEPGQFRIGPHTDFGTVTVLDREPGAGGLQVYSQEAG---WEDA
MAB_4434c|M.abscessus_ATCC_199 DGTTSQ------GVGAHRDSGVLTLLLTEPEVGGLQVEVDG----AWLEA
MAV_4913|M.avium_104 RAAGPQ------GVGAHRDAGVLTLLLAEPGSRGLQVRRGGPRGDGWIDV
TH_4524|M.thermoresistible__bu DPSAVDRP----GIGAHTDYECFTLLR--PTAPGLEVLNAAGQ---WIDV
: :*.* * .*:* * **:* * :.
Mflv_2580|M.gilvum_PYR-GCK PYDPAALTVNIGDLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYE
Mvan_4054|M.vanbaalenii_PYR-1 PYDPDALTVNIGDLLEYWSGRRWPSGRHRVLPPQPGAPEEDLVSLIYFYE
MSMEG_4685|M.smegmatis_MC2_155 PWEPGALTINIGDLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYE
MAB_4434c|M.abscessus_ATCC_199 PGREGAFIVNIGELLERASGGYLRATRHRVT---LTG--APRISVAYFFN
MAV_4913|M.avium_104 PPRQGAFIVNIGELLEAATRGYLRATEHRVN---LAGSTAERISVPYFFN
TH_4524|M.thermoresistible__bu PYLDDAFVLNIGDLLEIWTNGAFVATTHRVR-----RVTSERYSFPLFVN
* *: :***:*** : : *** *. * :
Mflv_2580|M.gilvum_PYR-GCK ANHDALVTPLSPP--------------IGRAEGLEPVLSADFIKQRLDAI
Mvan_4054|M.vanbaalenii_PYR-1 ANHDALVTPLDPP--------------VGRVSGLAPVTSADFIKERLDAI
MSMEG_4685|M.smegmatis_MC2_155 ANHDAVVTPLPPP--------------VGRAAGLAPVTSSAFIKERLDAI
MAB_4434c|M.abscessus_ATCC_199 PRLDARIPVLELPPELRDRARG---VSADPDDPIHATYGENAWKSRLRAH
MAV_4913|M.avium_104 PRLDARIPVLSLPPELRARAGERWTPSEDPADPIFSVYGRNAWKSRLRSH
TH_4524|M.thermoresistible__bu VDADTEVAPLAEFVDGTARYAP---VIAGEHLFAQTARSFRYLQDRIRRG
*: :. * . .. . :.*:
Mflv_2580|M.gilvum_PYR-GCK TVS-------------------
Mvan_4054|M.vanbaalenii_PYR-1 TVG-------------------
MSMEG_4685|M.smegmatis_MC2_155 TVG-------------------
MAB_4434c|M.abscessus_ATCC_199 PDVAAVHGHLDS----------
MAV_4913|M.avium_104 PDVASAHGFSAHHGAAD-----
TH_4524|M.thermoresistible__bu EVSLPDGAYPLSAFGRRAASPR