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M. thermoresistible (build 8) TH_4524 (-)

annotation: 2OG-Fe(II) oxygenase
coordinates: 2096853 - 2097878
length: 342

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4524--100% (342)2OG-Fe(II) oxygenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2580-3e-2329.84% (315) 2OG-Fe(II) oxygenase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4434c-8e-3334.72% (288) putative iron/ascorbate dependent oxidoreductase
M. marinum M-----
M. avium 104MAV_4913-2e-3637.16% (296) oxidoreductase, 2OG-Fe(II) oxygenase family protein
M. smegmatis MC2 155MSMEG_0414-1e-4240.70% (285) oxidoreductase, 2OG-Fe(II) oxygenase family protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4054-1e-2430.16% (315) 2OG-Fe(II) oxygenase

CLUSTAL 2.0.9 multiple sequence alignment


MAV_4913|M.avium_104                MSNDMCPVPG-----------VTAVPGVDLRADPDVLRDGLREAAHRVGF
MSMEG_0414|M.smegmatis_MC2_155      MPIRTLAVAGRLPDDGGVTALSTALPVVDLGDDAAVVTDQLRRVAHEVGF
MAB_4434c|M.abscessus_ATCC_199      MAVKTVAPKRLASNHG----RVAELPVIDLSSDSNQLRAALREVAHEVGF
Mflv_2580|M.gilvum_PYR-GCK          MSVIATVDLS---------------RWREGGPAAEDVAAQVDAGLQRAGF
Mvan_4054|M.vanbaalenii_PYR-1       MSVIATVDLS---------------RWRAGGAAADAVAADVDEGLQRAGF
TH_4524|M.thermoresistible__bu      MAGDFTSVPVIDIS----------ALRHGSGPGYRRAVTALGDAARHVGF
                                    *.                                      :    :..**

MAV_4913|M.avium_104                FYLTGHGVPADLVDRVLDAARRFFRLPQADKDAVAMVRSPH-FRGYTRLG
MSMEG_0414|M.smegmatis_MC2_155      FYLVGHGVPQDLVDRVLTAARRLFALPQADKDAIAMVNSPH-FRGYTRLG
MAB_4434c|M.abscessus_ATCC_199      FYLTGHGVSPQLVHEVLSAARKLFALSEADKEAIAMVRSPH-FRGFTRLG
Mflv_2580|M.gilvum_PYR-GCK          ILVTGHGVDPDLARDVRAAAREFFALDPTVKAGYSVPVGGRGWIGPGAEA
Mvan_4054|M.vanbaalenii_PYR-1       ILVSGHGVSASLARDVRAAAREFFALPDEVKSGYSVPVGGHGWIGPGAEA
TH_4524|M.thermoresistible__bu      AQLVGHGIDPALFDALVDRTRAFFALPAAEKHRVYIGNSTN-HRGYVPPG
                                      : ***:   *   :   :* :* *    *    :  . .   *    .

MAV_4913|M.avium_104                GERTRGAVDWREQIDIGPQRPPIGGLDKSDYRWLQGPNQWPAALPELPGL
MSMEG_0414|M.smegmatis_MC2_155      GELTGGQVDWREQIDIGPEREPLDDPAEP-YLRLQGPNQWPAALPELPAV
MAB_4434c|M.abscessus_ATCC_199      GELTGGLTDWREQIDVGPERAASPTADGRDYMWLQGPNQWPAAVPELRPA
Mflv_2580|M.gilvum_PYR-GCK          NGYAEGTETPPDLKESFSLGAETATGDAEVDRIWFAPNVWPREVPELAPL
Mvan_4054|M.vanbaalenii_PYR-1       NGYAEGTETPPDLKETFSLGAETATGDAEVDRIWFAPNVWPREVPALQPL
TH_4524|M.thermoresistible__bu      EEVFAGGTADTKEAFDLSYELPADDPRYLAGDPLLGPNQWP-ELTGFREA
                                         *     .     .                 .** **  :. :   

MAV_4913|M.avium_104                IAEWDAALSGVARTLLRHWAAALGSPADVFDAAFADAPATLIKIIRYPGR
MSMEG_0414|M.smegmatis_MC2_155      IAEWDAALAQVGRALLRHWAVALGNPADVFDEAFADTPATLIKIVRYPAQ
MAB_4434c|M.abscessus_ATCC_199      LESWDIALAEVGRKLLREWAIALGSDGAVFSEAFGDKPATLIKVIRYPSD
Mflv_2580|M.gilvum_PYR-GCK          VEEYTAQMRRVADDLLALCAHALGLSVNPFAALAS-APTWTMNINHYPPV
Mvan_4054|M.vanbaalenii_PYR-1       LTEYTAQMRGVADDLLALFAHALKLPANPFAELAS-TPTWTMNINHYPPV
TH_4524|M.thermoresistible__bu      VTAWYDAVFALSRAILRAFAVALGQPPDRFDRYVT-TPPSQLRLIHYPAD
                                    :  :   :  :.  :*   * **      *       *.  :.: :**  

MAV_4913|M.avium_104                AAGPQ------GVGAHRDAGVLTLLLAEPGSRGLQVRRGGPRGDGWIDVP
MSMEG_0414|M.smegmatis_MC2_155      AETSQ------GVGAHRDAGVLTLLLAEPGSRGLQVR--GPDG-VFIDVD
MAB_4434c|M.abscessus_ATCC_199      GTTSQ------GVGAHRDSGVLTLLLTEPEVGGLQVE---VDG-AWLEAP
Mflv_2580|M.gilvum_PYR-GCK          SVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVY---SEQAGWENAP
Mvan_4054|M.vanbaalenii_PYR-1       SVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVY---SEDAGWQDAP
TH_4524|M.thermoresistible__bu      PSAVDRP----GIGAHTDYECFTLLR--PTAPGLEVLN---AAGQWIDVP
                                        :       :*.* *   .*:*   *   **:*         : :. 

MAV_4913|M.avium_104                PRQGAFIVNIGELLEAATRGYLRATEHRVNLAGSTA---ERISVPYFFNP
MSMEG_0414|M.smegmatis_MC2_155      PLPGAFIVNIGEMLEIASGGYLRATEHRVQVSAS-----ERISVPYFFNP
MAB_4434c|M.abscessus_ATCC_199      GREGAFIVNIGELLERASGGYLRATRHRVTLTGAP-----RISVAYFFNP
Mflv_2580|M.gilvum_PYR-GCK          YDPAALTVNIGDLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYEA
Mvan_4054|M.vanbaalenii_PYR-1       YDPDALTVNIGDLLEYWSGRRWPSGRHRVLPPQPGAPEEDLVSLIYFYEA
TH_4524|M.thermoresistible__bu      YLDDAFVLNIGDLLEIWTNGAFVATTHRVRRVTS-----ERYSFPLFVNV
                                        *: :***::**  :     :  ***    .        *.  * : 

MAV_4913|M.avium_104                RLDARIPVLSLPPELRARAG-ERWTPSEDPADPIFSVYGRNAWKSRLRSH
MSMEG_0414|M.smegmatis_MC2_155      RLDAAIPVLALPDELAAQA---RGVTADPSNDRIYSVYGRNAWKSRVRAH
MAB_4434c|M.abscessus_ATCC_199      RLDARIPVLELPPELRDRA---RGVSAD-PDDPIHATYGENAWKSRLRAH
Mflv_2580|M.gilvum_PYR-GCK          NHDALVTPLSPPIGR---------------AEGLEPVLSADFIKQRLDAI
Mvan_4054|M.vanbaalenii_PYR-1       NHDALVTPLDPPVGR---------------VSGLAPVTSADFIKERLDAI
TH_4524|M.thermoresistible__bu      DADTEVAPLAEFVDGTARYAPVIAGEHLFAQTARSFRYLQDRIRRGEVSL
                                      *: :. *                               :  :    : 

MAV_4913|M.avium_104                PDVASAHGFSAHHGAAD-
MSMEG_0414|M.smegmatis_MC2_155      PDVAAAHGYV--------
MAB_4434c|M.abscessus_ATCC_199      PDVAAVHGHLDS------
Mflv_2580|M.gilvum_PYR-GCK          TVS---------------
Mvan_4054|M.vanbaalenii_PYR-1       TVG---------------
TH_4524|M.thermoresistible__bu      PDGAYPLSAFGRRAASPR
                                    .