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YALVDLLRGSRKPLSAARIAEEFGVSKRTIERDIQSLQLAGVPIYADHGVSGGYSILREHSLPPLNLTVP ESLAVLTGLGLLETSPYGAAARRARAKILAISREDQLAPIDEALASMFVIDAPSPSEAAVSLIPEAIAAR RVVRLEYTSEDGETRTTRDVEAMGLLRGGDAWLFVGWCRLREGIRGFQLNRIRHLEITAEVFSERDPEVL EADLSRWPTRRLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3967 | - | - | 100% (224) | TonB-dependent receptor |
| M. smegmatis MC2 155 | MSMEG_1359 | - | 1e-15 | 29.58% (213) | DeoR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3888 | - | 3e-09 | 24.64% (211) | hypothetical protein MSMEG_3888 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2122c | - | 2e-10 | 28.72% (188) | hypothetical protein Mb2122c |
| M. gilvum PYR-GCK | Mflv_5106 | - | 9e-13 | 28.04% (214) | helix-turn-helix, type 11 domain-containing protein |
| M. tuberculosis H37Rv | Rv2095c | - | 2e-10 | 28.72% (188) | hypothetical protein Rv2095c |
| M. leprae Br4923 | MLBr_01329 | - | 4e-13 | 28.93% (197) | hypothetical protein MLBr_01329 |
| M. abscessus ATCC 19977 | MAB_2186 | - | 9e-15 | 28.04% (214) | hypothetical protein MAB_2186 |
| M. marinum M | MMAR_3081 | - | 9e-13 | 30.32% (188) | hypothetical protein MMAR_3081 |
| M. avium 104 | MAV_2408 | - | 3e-12 | 29.79% (188) | hypothetical protein MAV_2408 |
| M. thermoresistible (build 8) | TH_1858 | - | 7e-14 | 28.10% (210) | DeoR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_2327 | - | 3e-13 | 30.32% (188) | hypothetical protein MUL_2327 |
| M. vanbaalenii PYR-1 | Mvan_2934 | - | 1e-109 | 87.95% (224) | helix-turn-helix, type 11 domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2122c|M.bovis_AF2122/97 ---MSALSTRLVRLLNMVPYFQANPRITR-AEAAAELG---------VTA
Rv2095c|M.tuberculosis_H37Rv ---MSALSTRLVRLLNMVPYFQANPRITR-AEAAAELG---------VTA
MMAR_3081|M.marinum_M ---MSPVSTRLVRLLNMVPYFQANPRITR-VEAAAELG---------VSA
MUL_2327|M.ulcerans_Agy99 ---MSPVSTRLVRLLNMVPYFQANPRITR-VEAAAELG---------VSA
MAV_2408|M.avium_104 ---MTPISTRLVRLLNMVPYFQANPRVTR-AKAAADLG---------VSA
MAB_2186|M.abscessus_ATCC_1997 ---MTELSNRLTRLLNMVPYFQANPGISA-AEAAADLG---------VTT
MSMEG_3967|M.smegmatis_MC2_155 -------------MYALVDLLRGSRKPLSAARIAEEFG---------VSK
Mvan_2934|M.vanbaalenii_PYR-1 -------MRRAERLYALVDLLRGSRRPLSAARLSQEFE---------VSK
Mflv_5106|M.gilvum_PYR-GCK ------MSETTGRVLQLLGLLQ-SRRVWSGDELAARLR---------VTT
TH_1858|M.thermoresistible__bu MWQAADVSETTSRVLRLLGLLQ-SRRVWSGEELAERLG---------VTT
MLBr_01329|M.leprae_Br4923 -----MATSKVERLVNLVIALLSTRGYMTAEKIRSSVAGYSDSPTVEAFS
: :: : . . . .
Mb2122c|M.bovis_AF2122/97 KQLEEDLNQLWMCGLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSP
Rv2095c|M.tuberculosis_H37Rv KQLEEDLNQLWMCGLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSP
MMAR_3081|M.marinum_M KQLEEDLNQLWMCGLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLKLTSP
MUL_2327|M.ulcerans_Agy99 KQLEEDLNQLWMCGLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLKLTSP
MAV_2408|M.avium_104 KQLEEDLNQLWMCGLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLRLTSP
MAB_2186|M.abscessus_ATCC_1997 KQLMADLNQLWMCGLPGYGPGDLIDLSFSEESIEVTFSAGIDRPLRLTSP
MSMEG_3967|M.smegmatis_MC2_155 RTIERDIQSLQLAGVPIYADHG------VSGGYSILREHSLP-PLNLTVP
Mvan_2934|M.vanbaalenii_PYR-1 RTIERDIQSLQLAGVPIYADYG------VSGGYSILREHSLP-PLNLTVP
Mflv_5106|M.gilvum_PYR-GCK RSVRRDIDRLRELGYPVHASTG------HGGGYQLGAGAALP-PLLLDPD
TH_1858|M.thermoresistible__bu RSVRRDVERLRDLGYPVHASRG------HGGGYQLGAGAALP-PLLLDPE
MLBr_01329|M.leprae_Br4923 RMFERDKNELRDLGIPLEVGKVSALD--PSEGYRINRDAYALPPVELTPD
: . * : * * * : *: *
Mb2122c|M.bovis_AF2122/97 EATGLLVALRALADIPGVVDPQAAR------SAIAKIAAAAG--------
Rv2095c|M.tuberculosis_H37Rv EATGLLVALRALADIPGVVDPQAAR------SAIAKIAAAAG--------
MMAR_3081|M.marinum_M EATGLLVALRALADIPGVVDPQAAR------SAIAKIAAAAGAA--GHSS
MUL_2327|M.ulcerans_Agy99 EATGLLVALRALADIPGVVDPQAAR------SAIAKIAAAAGAA--EHSS
MAV_2408|M.avium_104 EATGLLVALRALADIPGVVDPEAAR------SAIAKIEGAAGAVGHDTTQ
MAB_2186|M.abscessus_ATCC_1997 EATALLVALRALLDMPGTVDPEAAR------SAIAKIEEAVGALP----T
MSMEG_3967|M.smegmatis_MC2_155 ESLAVLTGLGLLETSPYGAAARRAR------AKILAISREDQLAPIDEAL
Mvan_2934|M.vanbaalenii_PYR-1 ESLAVLAGLALLETSPYGAAARRAR------AKVLAISREDQLAPVDEAL
Mflv_5106|M.gilvum_PYR-GCK EAVAVAVCLRVAAGGSVAGVGESALRALSKLDQVMPSRLRSQVAAVHDTT
TH_1858|M.thermoresistible__bu EAVAVAVCLRLAAGGSIAGVGESALRALGKLDQVMPARLRSQVSAVHEAT
MLBr_01329|M.leprae_Br4923 EAAAVAVATQLWESQELITATQGAL------LKLRAAGVDIDPLDTPVVI
*: .: . . * :
Mb2122c|M.bovis_AF2122/97 AVAAVAEQAPTESPAAAAVRAAVRNSRALTIDYYAASHDTLTTRIVDPIR
Rv2095c|M.tuberculosis_H37Rv AVAAVAEQAPTESPAAAAVRAAVRNSRALTIDYYAASHDTLTTRIVDPIR
MMAR_3081|M.marinum_M TLSAVDEPAPLESPAAAAVRSAVLDKRALTIDYYSASHDTLTTRTVDPIR
MUL_2327|M.ulcerans_Agy99 TLSAVDEPAPLESPAAAAVRSAVLDKRALTIDYYSASHDTLTTRTVDPIR
MAV_2408|M.avium_104 AATAVDEPAPAESRAAAAVRAAVQSRHALAIDYYSASRDTLTSRVVDPIR
MAB_2186|M.abscessus_ATCC_1997 DAAPAPLSARTESEAVTAVRSAVRNRQALRIEYYSASRDTLSERIVDPIR
MSMEG_3967|M.smegmatis_MC2_155 ASMFVIDAPSPSEAAVSLIPEAIAARRVVRLEYTSEDGETRTTRDVEAMG
Mvan_2934|M.vanbaalenii_PYR-1 ASMFVIDSQSPSEAAVSLIPEAIAARRVVRLVYTSEDGETHTTRDVEAMG
Mflv_5106|M.gilvum_PYR-GCK VTLAG-ATDTPVEPEVLMTLARASRDHEHVTVGYTDVRGNVTSRRVEPYQ
TH_1858|M.thermoresistible__bu TTLGPNQPDQPVAPDVLMTLARACRDHEHVNTGYTDRAGNRSRRRLEPYQ
MLBr_01329|M.leprae_Br4923 ASSSGVSSLRGSEDFLSILLSAIGSRQAVQFPYRPSRAEPYTMRNVEPWG
: . : * ::.
Mb2122c|M.bovis_AF2122/97 VLLIGGHSYLEAWSREAEGVRLFRFDRI-VDAAELGEP--AVPPESARQA
Rv2095c|M.tuberculosis_H37Rv VLLIGGHSYLEAWSREAEGVRLFRFDRI-VDAAELGEP--AVPPESARQA
MMAR_3081|M.marinum_M VLLIGGHSYLEAWSRESEGVRLFRFDRI-VDAVELGEP--AMPPEPAVQA
MUL_2327|M.ulcerans_Agy99 VLLIGGHSYLEAWSRESEGVRLFRFDRI-VDAVELGEP--AMPPEPAVQA
MAV_2408|M.avium_104 VLLIGGHSYLEAWSREAEGVRLFRFDRI-VEASELDEP--AAPPEPVLHA
MAB_2186|M.abscessus_ATCC_1997 IAVVGDHSYLEAWCRGSEGVRLFRFDRI-EQAEVLDQR--AAPPAPAVQT
MSMEG_3967|M.smegmatis_MC2_155 LLRGGDAWLFVGWCRLREGIRGFQLNRI-RHLEITAEV--FSERDP----
Mvan_2934|M.vanbaalenii_PYR-1 LLRGGDSWMFVGWCRLREGIRGFHLDRI-LHLEITGEV--FPGRDP----
Mflv_5106|M.gilvum_PYR-GCK LVTTGRRWYLMCFDRDRDDWRSLRLDRM-SDVRAVGTT--FIPREAPDAA
TH_1858|M.thermoresistible__bu LVTTGRRWYLLAYDRDRGDWRSLRLDRM-TDVRALGST--FTPRPAPDAA
MLBr_01329|M.leprae_Br4923 VITENSCWYLVGHDCDRNATRTFRLSRIGSEVAPIGPAGAVTVPDGVDLR
: . : * :::.*: .
Mb2122c|M.bovis_AF2122/97 PPDTSLFDGDLSLPSATLRVAPSASWMLEYYPIRELR--QLPDGSCEVVM
Rv2095c|M.tuberculosis_H37Rv PPDTSLFDGDLSLPSATLRVAPSASWMLEYYPIRELR--QLPDGSCEVAM
MMAR_3081|M.marinum_M PPDTSLFDGDPALPSATLRVAPSASWMFEYYPIRELR--QLADGSCEVAM
MUL_2327|M.ulcerans_Agy99 PPDTSLFDGDPALPSATLRVAPSASWMFEYYPIRELR--QLADGSCEVAM
MAV_2408|M.avium_104 PPDTSLFDGDPSLPSATLRVAPHASWMFEYYPMRDVR--ELPDGSCEAVM
MAB_2186|M.abscessus_ATCC_1997 ATDTGLFEADPSLPAATVIVGPSASWVFDYFPMRPTGT-QHPDGSLEAAM
MSMEG_3967|M.smegmatis_MC2_155 EVLEADLSRWPTRRLG----------------------------------
Mvan_2934|M.vanbaalenii_PYR-1 ALLATDLSRWRTRRLG----------------------------------
Mflv_5106|M.gilvum_PYR-GCK SYVRRAISSSPYPYVARVRYRAPADVVARVFPAASVDVEPDGPDACIVTV
TH_1858|M.thermoresistible__bu EFVRHSISASPYRHVARVRFRAPERVVSQHFPAAAVMIEPDGPDTCIVTA
MLBr_01329|M.leprae_Br4923 RIVSDAVAEVSTGATARVWVVDGRATALRHAGRPAGVRRLGGRDGQVIEL
. .
Mb2122c|M.bovis_AF2122/97 TYASEDWMTRLLLGFGSDVRVLAPESLAQRVRDAATAALDAYQAAAPP
Rv2095c|M.tuberculosis_H37Rv TYASEDWMTRLLLGFGSDVRVLAPESLAQRVRDAATAALDAYQAAAPP
MMAR_3081|M.marinum_M TYASEDWMTRLMLGFGSTVQVLEPESLAQRVRAAAATALNAYQAAELA
MUL_2327|M.ulcerans_Agy99 TYASEDWMTRLMLGFGSTVQVLEPESLAQRVRAAAATALNAYQAAELA
MAV_2408|M.avium_104 TYASEDWMTRLVLGLGSGVQVLAPHSLAQRVREAATAALAAYEALS--
MAB_2186|M.abscessus_ATCC_1997 TYASEDWMARLILGFGSAIRVLAPESLARRVRADATAALAAYQAS---
MSMEG_3967|M.smegmatis_MC2_155 ------------------------------------------------
Mvan_2934|M.vanbaalenii_PYR-1 ------------------------------------------------
Mflv_5106|M.gilvum_PYR-GCK GADDPQRMVPWLAMPGCEFEVLEPDEVVDAVRVVAERIARAGAGGD--
TH_1858|M.thermoresistible__bu GADDPQRIVLHLAAPGLPFEVLEPAEVAEAAAAVADLLTRASGRT---
MLBr_01329|M.leprae_Br4923 DIGSIDRLARDIAGHGADAVVLEPDALRDDVLIRLRAHAGTGPS----