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RRAERLYALVDLLRGSRRPLSAARLSQEFEVSKRTIERDIQSLQLAGVPIYADYGVSGGYSILREHSLPP LNLTVPESLAVLAGLALLETSPYGAAARRARAKVLAISREDQLAPVDEALASMFVIDSQSPSEAAVSLIP EAIAARRVVRLVYTSEDGETHTTRDVEAMGLLRGGDSWMFVGWCRLREGIRGFHLDRILHLEITGEVFPG RDPALLATDLSRWRTRRLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2934 | - | - | 100% (230) | helix-turn-helix, type 11 domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2933 | - | 2e-15 | 31.16% (215) | helix-turn-helix, type 11 domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1247 | - | 2e-12 | 27.57% (214) | helix-turn-helix, type 11 domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2122c | - | 4e-11 | 27.10% (214) | hypothetical protein Mb2122c |
| M. gilvum PYR-GCK | Mflv_5106 | - | 2e-13 | 28.50% (214) | helix-turn-helix, type 11 domain-containing protein |
| M. tuberculosis H37Rv | Rv2095c | - | 4e-11 | 27.10% (214) | hypothetical protein Rv2095c |
| M. leprae Br4923 | MLBr_01330 | - | 5e-12 | 27.88% (208) | putative DNA-binding protein |
| M. abscessus ATCC 19977 | MAB_2186 | - | 1e-12 | 27.96% (211) | hypothetical protein MAB_2186 |
| M. marinum M | MMAR_3081 | - | 9e-13 | 28.44% (225) | hypothetical protein MMAR_3081 |
| M. avium 104 | MAV_2408 | - | 1e-11 | 27.56% (225) | hypothetical protein MAV_2408 |
| M. smegmatis MC2 155 | MSMEG_3967 | - | 1e-109 | 87.95% (224) | TonB-dependent receptor |
| M. thermoresistible (build 8) | TH_1858 | - | 9e-14 | 29.33% (225) | DeoR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_2327 | - | 2e-13 | 28.89% (225) | hypothetical protein MUL_2327 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2122c|M.bovis_AF2122/97 ---MSALSTRLVRLLNMVPYFQANPRITR-AEAAAELGVTAKQLEEDLNQ
Rv2095c|M.tuberculosis_H37Rv ---MSALSTRLVRLLNMVPYFQANPRITR-AEAAAELGVTAKQLEEDLNQ
MMAR_3081|M.marinum_M ---MSPVSTRLVRLLNMVPYFQANPRITR-VEAAAELGVSAKQLEEDLNQ
MUL_2327|M.ulcerans_Agy99 ---MSPVSTRLVRLLNMVPYFQANPRITR-VEAAAELGVSAKQLEEDLNQ
MAV_2408|M.avium_104 ---MTPISTRLVRLLNMVPYFQANPRVTR-AKAAADLGVSAKQLEEDLNQ
MLBr_01330|M.leprae_Br4923 ---MTQLSTRLVRLLNMVPYFQANPRITR-AEAAADLGVSAKQLDQDFNQ
MAB_2186|M.abscessus_ATCC_1997 ---MTELSNRLTRLLNMVPYFQANPGISA-AEAAADLGVTTKQLMADLNQ
Mvan_2934|M.vanbaalenii_PYR-1 -------MRRAERLYALVDLLRGSRRPLSAARLSQEFEVSKRTIERDIQS
MSMEG_3967|M.smegmatis_MC2_155 -------------MYALVDLLRGSRKPLSAARIAEEFGVSKRTIERDIQS
Mflv_5106|M.gilvum_PYR-GCK ------MSETTGRVLQLLGLLQ-SRRVWSGDELAARLRVTTRSVRRDIDR
TH_1858|M.thermoresistible__bu MWQAADVSETTSRVLRLLGLLQ-SRRVWSGEELAERLGVTTRSVRRDVER
: :: :: . . : : *: : : *.:
Mb2122c|M.bovis_AF2122/97 LWMCGLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSPEATGLLVAL
Rv2095c|M.tuberculosis_H37Rv LWMCGLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSPEATGLLVAL
MMAR_3081|M.marinum_M LWMCGLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLKLTSPEATGLLVAL
MUL_2327|M.ulcerans_Agy99 LWMCGLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLKLTSPEATGLLVAL
MAV_2408|M.avium_104 LWMCGLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLRLTSPEATGLLVAL
MLBr_01330|M.leprae_Br4923 LWVCGLPGYGPGDLIDFEFSGDTIEVTFSAGIDRPLQLTSPEAIGLLVAL
MAB_2186|M.abscessus_ATCC_1997 LWMCGLPGYGPGDLIDLSFSEESIEVTFSAGIDRPLRLTSPEATALLVAL
Mvan_2934|M.vanbaalenii_PYR-1 LQLAGVPIYADYG------VSGGYSILREHSLP-PLNLTVPESLAVLAGL
MSMEG_3967|M.smegmatis_MC2_155 LQLAGVPIYADHG------VSGGYSILREHSLP-PLNLTVPESLAVLTGL
Mflv_5106|M.gilvum_PYR-GCK LRELGYPVHASTG------HGGGYQLGAGAALP-PLLLDPDEAVAVAVCL
TH_1858|M.thermoresistible__bu LRDLGYPVHASRG------HGGGYQLGAGAALP-PLLLDPEEAVAVAVCL
* * * : . .: .: ** * *: .: . *
Mb2122c|M.bovis_AF2122/97 RALADIPGVVDPQAARSAIAKIAAAAG---------------AVAAVAEQ
Rv2095c|M.tuberculosis_H37Rv RALADIPGVVDPQAARSAIAKIAAAAG---------------AVAAVAEQ
MMAR_3081|M.marinum_M RALADIPGVVDPQAARSAIAKIAAAAGAA---------GHSSTLSAVDEP
MUL_2327|M.ulcerans_Agy99 RALADIPGVVDPQAARSAIAKIAAAAGAA---------EHSSTLSAVDEP
MAV_2408|M.avium_104 RALADIPGVVDPEAARSAIAKIEGAAGAVGH-------DTTQAATAVDEP
MLBr_01330|M.leprae_Br4923 RALANIPGVVDPEAVRSAIAKIEAAAVVMGN-------EATGSVASVDTR
MAB_2186|M.abscessus_ATCC_1997 RALLDMPGTVDPEAARSAIAKIEEAVGALP-----------TDAAPAPLS
Mvan_2934|M.vanbaalenii_PYR-1 ALLET---SPYGAAARRAR---AKVLAISREDQLAPVDEALASMFVIDSQ
MSMEG_3967|M.smegmatis_MC2_155 GLLET---SPYGAAARRAR---AKILAISREDQLAPIDEALASMFVIDAP
Mflv_5106|M.gilvum_PYR-GCK RVAAGGSVAGVGESALRALSKLDQVMPSRLRSQVAAVHDTTVTLAG-ATD
TH_1858|M.thermoresistible__bu RLAAGGSIAGVGESALRALGKLDQVMPARLRSQVSAVHEATTTLGPNQPD
:. *
Mb2122c|M.bovis_AF2122/97 APTESPAAAAVRAAVRNSRALTIDYYAASHDTLTTRIVDPIRVLLIGGHS
Rv2095c|M.tuberculosis_H37Rv APTESPAAAAVRAAVRNSRALTIDYYAASHDTLTTRIVDPIRVLLIGGHS
MMAR_3081|M.marinum_M APLESPAAAAVRSAVLDKRALTIDYYSASHDTLTTRTVDPIRVLLIGGHS
MUL_2327|M.ulcerans_Agy99 APLESPAAAAVRSAVLDKRALTIDYYSASHDTLTTRTVDPIRVLLIGGHS
MAV_2408|M.avium_104 APAESRAAAAVRAAVQSRHALAIDYYSASRDTLTSRVVDPIRVLLIGGHS
MLBr_01330|M.leprae_Br4923 PFSESHAVAAVRAAVRDKQALVIDYYSASHDTLTSRIVDPIRVLLVGDHS
MAB_2186|M.abscessus_ATCC_1997 ARTESEAVTAVRSAVRNRQALRIEYYSASRDTLSERIVDPIRIAVVGDHS
Mvan_2934|M.vanbaalenii_PYR-1 SPSE-AAVSLIPEAIAARRVVRLVYTSEDGETHTTRDVEAMGLLRGGDSW
MSMEG_3967|M.smegmatis_MC2_155 SPSE-AAVSLIPEAIAARRVVRLEYTSEDGETRTTRDVEAMGLLRGGDAW
Mflv_5106|M.gilvum_PYR-GCK TPVEPEVLMTLARASRDHEHVTVGYTDVRG-NVTSRRVEPYQLVTTGRRW
TH_1858|M.thermoresistible__bu QPVAPDVLMTLARACRDHEHVNTGYTDRAG-NRSRRRLEPYQLVTTGRRW
. : * . : * . : * ::. : *
Mb2122c|M.bovis_AF2122/97 YLEAWSREAEGVRLFRFDRIVDAAELGEPAVPPESARQAPPDTSLFDGDL
Rv2095c|M.tuberculosis_H37Rv YLEAWSREAEGVRLFRFDRIVDAAELGEPAVPPESARQAPPDTSLFDGDL
MMAR_3081|M.marinum_M YLEAWSRESEGVRLFRFDRIVDAVELGEPAMPPEPAVQAPPDTSLFDGDP
MUL_2327|M.ulcerans_Agy99 YLEAWSRESEGVRLFRFDRIVDAVELGEPAMPPEPAVQAPPDTSLFDGDP
MAV_2408|M.avium_104 YLEAWSREAEGVRLFRFDRIVEASELDEPAAPPEPVLHAPPDTSLFDGDP
MLBr_01330|M.leprae_Br4923 YLEAWSREAEGVRLFRFDRIVVARELDEPAAAPETVRKALPDTSFFDDDP
MAB_2186|M.abscessus_ATCC_1997 YLEAWCRGSEGVRLFRFDRIEQAEVLDQRAAPPAPAVQTATDTGLFEADP
Mvan_2934|M.vanbaalenii_PYR-1 MFVGWCRLREGIRGFHLDRILHLEITGEVFPGRDP----ALLATDLSRWR
MSMEG_3967|M.smegmatis_MC2_155 LFVGWCRLREGIRGFQLNRIRHLEITAEVFSERDP----EVLEADLSRWP
Mflv_5106|M.gilvum_PYR-GCK YLMCFDRDRDDWRSLRLDRMSDVRAVGTTFIPREAPDAASYVRRAISSSP
TH_1858|M.thermoresistible__bu YLLAYDRDRGDWRSLRLDRMTDVRALGSTFTPRPAPDAAEFVRHSISASP
: : * . * ::::*: . :.
Mb2122c|M.bovis_AF2122/97 SLPSATLRVAPSASWMLEYYPIR--ELRQLPDGSCEVVMTYASEDWMTRL
Rv2095c|M.tuberculosis_H37Rv SLPSATLRVAPSASWMLEYYPIR--ELRQLPDGSCEVAMTYASEDWMTRL
MMAR_3081|M.marinum_M ALPSATLRVAPSASWMFEYYPIR--ELRQLADGSCEVAMTYASEDWMTRL
MUL_2327|M.ulcerans_Agy99 ALPSATLRVAPSASWMFEYYPIR--ELRQLADGSCEVAMTYASEDWMTRL
MAV_2408|M.avium_104 SLPSATLRVAPHASWMFEYYPMR--DVRELPDGSCEAVMTYASEDWMTRL
MLBr_01330|M.leprae_Br4923 LLPSATLWVARSVSWIFEYYPMR--QAHELPDGSFQAVMTYASDAWMTRL
MAB_2186|M.abscessus_ATCC_1997 SLPAATVIVGPSASWVFDYFPMRP-TGTQHPDGSLEAAMTYASEDWMARL
Mvan_2934|M.vanbaalenii_PYR-1 TRRLG---------------------------------------------
MSMEG_3967|M.smegmatis_MC2_155 TRRLG---------------------------------------------
Mflv_5106|M.gilvum_PYR-GCK YPYVARVRYRAPADVVARVFPAASVDVEPDGPDACIVTVGADDPQRMVPW
TH_1858|M.thermoresistible__bu YRHVARVRFRAPERVVSQHFPAAAVMIEPDGPDTCIVTAGADDPQRIVLH
.
Mb2122c|M.bovis_AF2122/97 LLGFGSDVRVLAPESLAQRVRDAATAALDAYQAAAPP
Rv2095c|M.tuberculosis_H37Rv LLGFGSDVRVLAPESLAQRVRDAATAALDAYQAAAPP
MMAR_3081|M.marinum_M MLGFGSTVQVLEPESLAQRVRAAAATALNAYQAAELA
MUL_2327|M.ulcerans_Agy99 MLGFGSTVQVLEPESLAQRVRAAAATALNAYQAAELA
MAV_2408|M.avium_104 VLGLGSGVQVLAPHSLAQRVREAATAALAAYEALS--
MLBr_01330|M.leprae_Br4923 VLGFGSAVQVQAPEALAYRVRNAAVAALESYQVTAQA
MAB_2186|M.abscessus_ATCC_1997 ILGFGSAIRVLAPESLARRVRADATAALAAYQAS---
Mvan_2934|M.vanbaalenii_PYR-1 -------------------------------------
MSMEG_3967|M.smegmatis_MC2_155 -------------------------------------
Mflv_5106|M.gilvum_PYR-GCK LAMPGCEFEVLEPDEVVDAVRVVAERIARAGAGGD--
TH_1858|M.thermoresistible__bu LAAPGLPFEVLEPAEVAEAAAAVADLLTRASGRT---