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MVHIDLGTFGLTVTPGTPGAEEIEALGFGALWVNGGQLDRLERLTDLLATTRRAAVAPAIIPPDVYGPDA VVDLFGRAEVAAPGRLMIGLGSSSQPRPRAALGAYVDELGAIPRERRLLAAFGPRMLDTARDRFGGAMPG MVTPEYTAIARERLGPDRLLVVGLYAVLDTDADAARETARVPLRFLMGMRSYVNSALRQGFSETDIATVS DDLVDRLVAWGSADDIAKQARRHREAGADHVYLSVLHNDTQPSGVAAARLLAPVLFG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3809 | - | - | 100% (267) | hypothetical protein MSMEG_3809 |
| M. smegmatis MC2 155 | MSMEG_1514 | - | 1e-41 | 38.29% (269) | hypothetical protein MSMEG_1514 |
| M. smegmatis MC2 155 | MSMEG_4141 | - | 4e-37 | 37.64% (263) | hypothetical protein MSMEG_4141 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3492 | - | 1e-37 | 39.29% (252) | hypothetical protein Mb3492 |
| M. gilvum PYR-GCK | Mflv_5005 | - | 3e-42 | 41.76% (261) | hypothetical protein Mflv_5005 |
| M. tuberculosis H37Rv | Rv3463 | - | 1e-37 | 39.29% (252) | hypothetical protein Rv3463 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3778 | - | 6e-40 | 41.32% (242) | hypothetical protein MAB_3778 |
| M. marinum M | MMAR_1083 | - | 3e-38 | 37.45% (275) | hypothetical protein MMAR_1083 |
| M. avium 104 | MAV_4405 | - | 5e-40 | 37.73% (273) | hypothetical protein MAV_4405 |
| M. thermoresistible (build 8) | TH_0027 | - | 7e-42 | 40.71% (253) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0842 | - | 7e-38 | 40.48% (252) | hypothetical protein MUL_0842 |
| M. vanbaalenii PYR-1 | Mvan_5686 | - | 1e-75 | 58.05% (267) | hypothetical protein Mvan_5686 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1083|M.marinum_M ------------MTNAVSLKPELGRFGVWLGSRS--ITPELAGQIESLGY
MAV_4405|M.avium_104 ------------MTEGVSLKPDLGPFGVWLSTRS--ITAELAARIESLGY
TH_0027|M.thermoresistible__bu ------------MTDAVSLKPDLGRFGVWTGG-P--IPRELAAEIEKLGY
Mb3492|M.bovis_AF2122/97 ----MTNCAAGK---PSSG-PNLGRFGSFGRG----VTPQQATEIEALGY
Rv3463|M.tuberculosis_H37Rv ----MTNCAAGK---PSSG-PNLGRFGSFGRG----VTPQQATEIEALGY
MUL_0842|M.ulcerans_Agy99 MPAPETDSDARSSASPAAGKPNLGRFGSFGRG----VTPAQARDIEALGY
Mflv_5005|M.gilvum_PYR-GCK ---------------MSDVTPDLGRFGSFGRG----VTPEQAQQIEALGY
MAB_3778|M.abscessus_ATCC_1997 -----------------MGESKLNRYGVWKGGP---VTPEQARTIEDLGY
MSMEG_3809|M.smegmatis_MC2_155 -----------------MVHIDLGTFGLTVTPG-----TPGAEEIEALGF
Mvan_5686|M.vanbaalenii_PYR-1 -----------------MSRISLGRYGFSVEVRDDDSHLAAALTVEGLGF
.*. :* * :* **:
MMAR_1083|M.marinum_M GAAWIGASPDADLAWVEPALEQTTSLQLATGIVNIWSAPADEVAASYQRI
MAV_4405|M.avium_104 GAAWIGGSPDAELSWVDPALAGTTSLHLATGIVNIWSAPAAAVAESFHRI
TH_0027|M.thermoresistible__bu RALWVGGSPAAELDFVEPILEATETLQVATGIVNIWTAPARTVAQSFHRI
Mb3492|M.bovis_AF2122/97 GAVWVGGSPPAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFHRI
Rv3463|M.tuberculosis_H37Rv GAVWVGGSPPAALSWVEPILQATTTLCVATGIVNIWSAPAQRVAESFHRI
MUL_0842|M.ulcerans_Agy99 GAVWVGGSPPAELAWVEPILAATTTLQVATGIVNIWSAPAKPVAESFHRI
Mflv_5005|M.gilvum_PYR-GCK GAVWVGGSPPAELDWVEPLLAATTTLQVATGIVNIWTADAGPVAESFHRI
MAB_3778|M.abscessus_ATCC_1997 GSVWVGGVFTADLAYVEPLLAVTENLTVASGIVNIWTSPVDEIAAAFHRI
MSMEG_3809|M.smegmatis_MC2_155 GALWVNGGQLDRLERLTDLLATTRRAAVAPAIIPPDVYGPDAVVDLFGRA
Mvan_5686|M.vanbaalenii_PYR-1 GTLWLNGGQLDRLDRLTDLLAATTTAVVGSAIIPPDRYSAAEVSELFARA
: *:.. * : * * :...*: : : *
MMAR_1083|M.marinum_M ESAHPGRFLLGVGVGHPEHTQEYQ---KPYDALVAYLDDLDKAMVPDSRR
MAV_4405|M.avium_104 ESGHPGRFLLGIGAGHREHTREYV---KPYDAVVSYLDELDAAVIPTSRR
TH_0027|M.thermoresistible__bu EKAYPGRFVLGLGVGHPEATEEYA---KPYEAMVTYLDVLDEATVPTSRR
Mb3492|M.bovis_AF2122/97 EAAYPGRFLLGIGVGHAEMISEYR---KPYNALVEYLDRLDDYGVPANRR
Rv3463|M.tuberculosis_H37Rv EAAYPGRFLLGIGVGHAEMISEYR---KPYNALVEYLDRLDDYGVPANRR
MUL_0842|M.ulcerans_Agy99 EAAYPGRFLLGIGVGHPEAITEYHSTGNAVDALIEYLNRLDDYGVPANRR
Mflv_5005|M.gilvum_PYR-GCK ESAHPGRFLLGIGVGHPEAHQQYR---RPIDALVEYLDKLDEYGVPRGRR
MAB_3778|M.abscessus_ATCC_1997 EAAYPGRFLLGVGAGHPEASAEYR---KPYDALVEYLDGLDAAGVPKERR
MSMEG_3809|M.smegmatis_MC2_155 EVAAPGRLMIGLGSSSQP---------RPRAALGAYVDELG--AIPRERR
Mvan_5686|M.vanbaalenii_PYR-1 EADAPGRLMVGLGSSHRP---------RALTLLGDYLDELD--AVPEDRR
* ***:::*:* . .. : *:: *. :* **
MMAR_1083|M.marinum_M VLAALGPRMLRLAAQRSAGAHPYLTTPEHTGTARQLVGNTVFLAPEHKVV
MAV_4405|M.avium_104 VLAALGPRMLRLAAQRSAGAHPFLTTPEHTAKARELVGGSVFLAPAHKVV
TH_0027|M.thermoresistible__bu VLAALGPRMLQLAAQRSAGAHPYLTTPQHTGQARNRIGPSVFLAPEHKVV
Mb3492|M.bovis_AF2122/97 VVAALGPRVLGLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVV
Rv3463|M.tuberculosis_H37Rv VVAALGPRVLGLSARRSAGAHPYLTTPEHTARARELIGPSAFLAPEHKVV
MUL_0842|M.ulcerans_Agy99 VVAALGPRVLRLAARRSAGAHPYLTTPEHTGAARELIGPSAFLAPEHKVV
Mflv_5005|M.gilvum_PYR-GCK VVAALGPKVLKLSADRAAGAHPYLTTPEHTARARELIGPEAFLAPEHKVV
MAB_3778|M.abscessus_ATCC_1997 VLAALGPKVLKLSADRTAGAHPYLTTPEHTRQAREIIGPDALLVPEHKVV
MSMEG_3809|M.smegmatis_MC2_155 LLAAFGPRMLDTARDRFGGAMPGMVTPEYTAIARERLGPDRLLVVGLYAV
Mvan_5686|M.vanbaalenii_PYR-1 LLAAFGPRALAVARDRFAGAMPMLFTAQRTAEVRRVLGADRTLSVGLYVV
::**:**: * : * .** * : *.: * .*. :* * .*
MMAR_1083|M.marinum_M LTT----------DAAQARAVGRKFIDFYLGLSNYVNNWLKLGFTEDDVR
MAV_4405|M.avium_104 LTT----------DRDRARAAGRQAIEHNLGLSNYVHNWLRLGFTEADVR
TH_0027|M.thermoresistible__bu LDT----------DAAAAREIGRQTIGFYLRLRNYVNNWKQLGFTDDDIA
Mb3492|M.bovis_AF2122/97 LTT----------DSARARTVGRQALDMYFNLANYRNNWKRLGFTDDEVS
Rv3463|M.tuberculosis_H37Rv LTT----------DSARARTVGRQALDMYFNLANYRNNWKRLGFTDDEVS
MUL_0842|M.ulcerans_Agy99 LTT----------DAQRARAVGRKALDIYLNLANYLNSWKRLGFSERDIA
Mflv_5005|M.gilvum_PYR-GCK LTTDERSREEHVTDPDRAREVGRKALEIYLDLANYLNSWKRLGFSDEDVA
MAB_3778|M.abscessus_ATCC_1997 LST----------DAPSAREIGRRTVDFYLTLSNYVNNWKRLGFNDEDLT
MSMEG_3809|M.smegmatis_MC2_155 LDT----------DADAARETARVPLRFLMGMRSYVNSALRQGFSETDIA
Mvan_5686|M.vanbaalenii_PYR-1 LDE----------DPATARATARRPLQFLTAMPQYRKSLERQGFSPDDIS
* * ** .* : : .* :. : **. ::
MMAR_1083|M.marinum_M KPGSDRLIDALVAYGTPDQIARRLGEHLEAGADHVAIQVLRPSREDKPMA
MAV_4405|M.avium_104 PPGSDRLIDAVIGYGTPQAVAARLREHLDAGADHVAIQVLGGDSEETLLP
TH_0027|M.thermoresistible__bu EPGSDELIDAMVAHGTAEQVADALREHLDRGADHVAIQVLGG--RERLLP
Mb3492|M.bovis_AF2122/97 RPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTE--DDNLVS
Rv3463|M.tuberculosis_H37Rv RPGSDRLVDAVVAYGTPDAIAARLNEHLLAGADHVPIQVLTE--DDNLVS
MUL_0842|M.ulcerans_Agy99 RPGSDRLVDAVVAYGTPAAIAARLNEHLQAGADHVPVQVLTK--SENLVP
Mflv_5005|M.gilvum_PYR-GCK KPGSDRLVDAVVAYGTAEQIAARLREHLDAGADHVPVQVLTG--SDKLVP
MAB_3778|M.abscessus_ATCC_1997 SPGSDAFIDAVVAHGTAAEIATRLNEHLDAGADQVLIQVLG---DKGLVD
MSMEG_3809|M.smegmatis_MC2_155 T-VSDDLVDRLVAWGSADDIAKQARRHREAGADHVYLSVLHNDTQPSGVA
Mvan_5686|M.vanbaalenii_PYR-1 G-ISDRLVDTLVAWGGPRHVLDHAARLHAAGADHVQLNVLGADGQPTGVA
** ::* ::. * . : . ***:* :.** :
MMAR_1083|M.marinum_M ALT-------ELSGALGLTR-----------------------
MAV_4405|M.avium_104 ALT-------ELADALGLTRTN---------------------
TH_0027|M.thermoresistible__bu TLXXSPRCGPNWGRCTSWSRARVWWTSPRSPRSAGRPGSGSSM
Mb3492|M.bovis_AF2122/97 ALT-------ELAKPLRLT------------------------
Rv3463|M.tuberculosis_H37Rv ALT-------ELAKPLRLT------------------------
MUL_0842|M.ulcerans_Agy99 ALA-------ELAGPLGLAGA----------------------
Mflv_5005|M.gilvum_PYR-GCK ALA-------ELAGPLGLESTEEQR------------------
MAB_3778|M.abscessus_ATCC_1997 TLT-------SLADALR--------------------------
MSMEG_3809|M.smegmatis_MC2_155 AAR--------LLAPVLFG------------------------
Mvan_5686|M.vanbaalenii_PYR-1 AAR--------LLA-AEFG------------------------
: