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GDTLTAGQKLERGGSLQSGNGAYTLTLQDDGNLVLYARDKAVWSTGTNGQDVVRAEVQTDGNFVLYTAEK PVWHTDTKGKKEVKLVLQDDRNLVLYAKDGPAWSSKTDTTEPPPPAPEPEKEAEVAPAAAEEAAPAPVAE PAPAEPAPAAPPPAPPAPRTYTVVSGDTLWAIAERFYGDGSKYQQIADASGIANPDLIHPGQVLTIP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3662 | - | - | 100% (208) | mannose-binding lectin |
| M. smegmatis MC2 155 | MSMEG_3437 | - | 8e-10 | 41.76% (91) | putative esterase family protein |
| M. smegmatis MC2 155 | MSMEG_3288 | - | 2e-08 | 51.02% (49) | LysM domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1319 | - | 7e-10 | 63.04% (46) | hypothetical protein Mb1319 |
| M. gilvum PYR-GCK | Mflv_3345 | - | 4e-07 | 50.00% (56) | fibronectin-attachment family protein |
| M. tuberculosis H37Rv | Rv1288 | - | 7e-10 | 63.04% (46) | hypothetical protein Rv1288 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 2e-05 | 35.94% (64) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_2373 | - | 2e-62 | 60.77% (209) | putative mannose-specific lectin precursor |
| M. marinum M | MMAR_3773 | - | 2e-81 | 72.25% (209) | hypothetical protein MMAR_3773 |
| M. avium 104 | MAV_1722 | - | 3e-08 | 50.85% (59) | secreted protein |
| M. thermoresistible (build 8) | TH_3264 | - | 1e-05 | 34.38% (96) | PUTATIVE virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3720 | - | 9e-82 | 70.89% (213) | hypothetical protein MUL_3720 |
| M. vanbaalenii PYR-1 | Mvan_3343 | - | 1e-09 | 50.00% (54) | FHA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3773|M.marinum_M --------------------------------------------------
MUL_3720|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_3662|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2373|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1319|M.bovis_AF2122/97 MVSTHAVVAGETLSALALRFYGDAELYRLIAAAS----------------
Rv1288|M.tuberculosis_H37Rv MVSTHAVVAGETLSALALRFYGDAELYRLIAAASGIADPDVVNVGQRLIM
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_3345|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3343|M.vanbaalenii_PYR-1 ------------MRVRRKMSPSMNRISVTTLAALGMVWPFLFYGAPAAAE
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
TH_3264|M.thermoresistible__bu --------VTVGAVGVLIVAMLVVGALQYDKLMFWTDKSYTAYFTQAGGL
MMAR_3773|M.marinum_M ------------------------------------MPMSDTLTEGQQLV
MUL_3720|M.ulcerans_Agy99 --------------------------------------MSDTLTEGQQLV
MSMEG_3662|M.smegmatis_MC2_155 --------------------------------------MGDTLTAGQKLE
MAB_2373|M.abscessus_ATCC_1997 --------------------------------------MADTLTQGQKLD
Mb1319|M.bovis_AF2122/97 -----------------------------------GIADPDVVNVGQRLI
Rv1288|M.tuberculosis_H37Rv PDFTRYTVVAGDTLSALALRFYGDAELNWLIAAASGIADPDVVNVGQRLI
MAV_1722|M.avium_104 --------------------------------------------------
Mflv_3345|M.gilvum_PYR-GCK ------------MTMDQPNVFPHRRAGTPTSIRRSVVTGATTAALAAALA
Mvan_3343|M.vanbaalenii_PYR-1 PSPGVPCLEILQQLAAAPPSVPETLDTAANALNNVVPEAAPALPPVPVAE
MLBr_02395|M.leprae_Br4923 ---------------------------------------MTDQPPPSGSN
TH_3264|M.thermoresistible__bu RAGAMVQVSGLRSGRVTSVALEGSQVRVKFDVNRKVRLGDRSEAAIKTKS
MMAR_3773|M.marinum_M P----GESLVSKNGAYTLTLQDDGNLVLASRGTPLWATATN-----GQQV
MUL_3720|M.ulcerans_Agy99 P----GESLVSKNGAYTLTLQDDGNLVLASRGTPLWASATN-----GQQV
MSMEG_3662|M.smegmatis_MC2_155 R----GGSLQSGNGAYTLTLQDDGNLVLYARDKAVWSTGTN-----GQDV
MAB_2373|M.abscessus_ATCC_1997 S----GQSLTSNNGAYTLTLQDDGNLVLTEGGSPVWASDTS-----GHSA
Mb1319|M.bovis_AF2122/97 MPDFTRYTVVAGDTLSALAARFYGDASLYPLIAAVNGIADPGVIDVGQVL
Rv1288|M.tuberculosis_H37Rv MPDFTRYTVVAGDTLSALAARFYGDASLYPLIAAVNGIADPGVIDVGQVL
MAV_1722|M.avium_104 --------MGFDPNVPAAGPAPDAPPPPAPDAPPAPAPDAP-----PAPD
Mflv_3345|M.gilvum_PYR-GCK LPGIANAQPAPTPTPAPPPPAVGAPQAPAPDAPAAPAPAPPADPNAPAPA
Mvan_3343|M.vanbaalenii_PYR-1 VVHGLTALAAPGPVPPVDAAPLAAPPVPPVDAAPLAAPLVQAAAG-PVPA
MLBr_02395|M.leprae_Br4923 PTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPP-----PPPP
TH_3264|M.thermoresistible__bu LLGAKYLEITTRGDGVLGGPIPADRTTPPYELPDALGDLATTISGLDTIG
.
MMAR_3773|M.marinum_M VRAEVQRDGN---FVVY-TADKPVWHTDTKG-----KKNVRLVLQDDRN-
MUL_3720|M.ulcerans_Agy99 VRAEVQRDGN---FVVY-TADKPVWHTDTKG-----KKNVRLVLQDDRN-
MSMEG_3662|M.smegmatis_MC2_155 VRAEVQTDGN---FVLY-TAEKPVWHTDTKG-----KKEVKLVLQDDRN-
MAB_2373|M.abscessus_ATCC_1997 GRAEVQSDGN---FVVYDNGGGALWSSNTEG-----RTDVKLVLQDDRN-
Mb1319|M.bovis_AF2122/97 VIFIGRSDGFGLRIVDRNENDPRLWYYRFQTSAIGWNPGVNVLLPDDYRT
Rv1288|M.tuberculosis_H37Rv VIFIGRSDGFGLRIVDRNENDPRLWYYRFQTSAIGWNPGVNVLLPDDYRT
MAV_1722|M.avium_104 APPPPAPDAP----PPPAPDAPPAPGPDVPP------PPAPKAYSVNWD-
Mflv_3345|M.gilvum_PYR-GCK APPATPPADPNAPVPPPADPNAPAPAGPEAP-----AAPAPEPGRVDNAA
Mvan_3343|M.vanbaalenii_PYR-1 AAPIPVVAPPIPAVIPLAPPVPVVAPPPAVP----VAAPVEAVLASAPEP
MLBr_02395|M.leprae_Br4923 GGSYPPPPPPGGSYPPPPPSTGAYAPPPPGP-------AIRSLPKEAYT-
TH_3264|M.thermoresistible__bu VSDSLATLAETFSGTAPDVQQAVQGLSAFSETIDRRNRHLRELLADARKV
MMAR_3773|M.marinum_M --------------------------------------LVLYAADGPAWS
MUL_3720|M.ulcerans_Agy99 --------------------------------------LVLYAADGPAWS
MSMEG_3662|M.smegmatis_MC2_155 --------------------------------------LVLYAKDGPAWS
MAB_2373|M.abscessus_ATCC_1997 --------------------------------------LVLYSGADSVWS
Mb1319|M.bovis_AF2122/97 SGRTYPVLYLFHGGGTDQDFRTFDFLGIRDLTAGKPIIIVMPDGGHAGWY
Rv1288|M.tuberculosis_H37Rv SGRTYPVLYLFHGGGTDQDFRTFDFLGIRDLTAGKPIIIVMPDGGHAGWY
MAV_1722|M.avium_104 --------------------------------------AIAQCESGGNWG
Mflv_3345|M.gilvum_PYR-GCK G--------------------------------------GFSYVVPAGWK
Mvan_3343|M.vanbaalenii_PYR-1 ---------------------------------------VAPAPVPPAPG
MLBr_02395|M.leprae_Br4923 ---------------------------------------FWVTRVLAYVI
TH_3264|M.thermoresistible__bu SDVLGERSEQIVKLVRHSNALLIALQQQSVALDQISHHISLFARQTSELV
MMAR_3773|M.marinum_M THTETDAPPPP--------------------------EPTAAAEATASDT
MUL_3720|M.ulcerans_Agy99 THTETDAPPPP--------------------------EPTAAAEATASDT
MSMEG_3662|M.smegmatis_MC2_155 SKTDTTEPPPP--------------------------APEPEKEAEVAPA
MAB_2373|M.abscessus_ATCC_1997 SGTQTDTPVAP--------------------------AAES---------
Mb1319|M.bovis_AF2122/97 SNPVSSFVGPRNWETFHIAQLLPWIEANFRTYAEYDGRAVAGFSMGGFGA
Rv1288|M.tuberculosis_H37Rv SNPVSSFVGPRNWETFHIAQLLPWIEANFRTYAEYDGRAVAGFSMGGFGA
MAV_1722|M.avium_104 INTGNGYAGGL---------------------------------------
Mflv_3345|M.gilvum_PYR-GCK VSDATQLSYGQALLSKLPPE-----------------GSPPDAQPPNDTS
Mvan_3343|M.vanbaalenii_PYR-1 EAAPVELAAAPPPVEPAPPAP---------------PEPPPTAPTDVAPA
MLBr_02395|M.leprae_Br4923 DNIPATVLLGIG------------------------MLIQTLTKQEACVT
TH_3264|M.thermoresistible__bu AENRAELRPALDKLNG---------------------VLTIVDNRRDRLQ
MMAR_3773|M.marinum_M AQRVDTTPEPVAAAVAEPAPPEP-AAEPAPRTYTVVS------------G
MUL_3720|M.ulcerans_Agy99 AQRVDTTPEAVAAAVAEPAPPEP-AAEPAPRTYTVVS------------G
MSMEG_3662|M.smegmatis_MC2_155 AAEEAAPAPVAEPAPAEPAPAAPPPAPPAPRTYTVVS------------G
MAB_2373|M.abscessus_ATCC_1997 -------VEVAPAAVEEPAPAPE------PRTYTVES------------G
Mb1319|M.bovis_AF2122/97 LKYAAKYYGHFASASSHSGPASLRRDFGLVVHWANLSSAVLDLGGGTVYG
Rv1288|M.tuberculosis_H37Rv LKYAAKYYGHFASASSHSGPASLRRDFGLVVHWANLSSAVLDLGGGTVYG
MAV_1722|M.avium_104 --QFTSSTWHANGGSGSPAGASR---------------------------
Mflv_3345|M.gilvum_PYR-GCK VLLGRLDLKLFAGAETDNTKAAQRLASDMGEFFMPFPGTRVNQQVVPLDA
Mvan_3343|M.vanbaalenii_PYR-1 VAEPVAPEPVMAPAAAEPTPAAVAPVEPGPAPVELVAAAEPAPIMEPAAA
MLBr_02395|M.leprae_Br4923 DITQYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWNYG-------YRQG
TH_3264|M.thermoresistible__bu ETLPLLNKYVMQLGESVASGPFFKAYIVNLLPGQFLQPFIDAAFSDLGLD
MMAR_3773|M.marinum_M DTLWAIAER------------------FYGDGS-----------------
MUL_3720|M.ulcerans_Agy99 DTLWAIAER------------------FYGDGS-----------------
MSMEG_3662|M.smegmatis_MC2_155 DTLWAIAER------------------FYGDGS-----------------
MAB_2373|M.abscessus_ATCC_1997 DTLWAIAER------------------FYGDGN-----------------
Mb1319|M.bovis_AF2122/97 APLWDQARVSADNPVERIDSYRNKRI-FLVAGTSPDPANWFDSVNETQVL
Rv1288|M.tuberculosis_H37Rv APLWDQARVSADNPVERIDSYRNKRI-FLVAGTSPDPANWFDSVNETQVL
MAV_1722|M.avium_104 EEQIRVAEN-----------------------------------------
Mflv_3345|M.gilvum_PYR-GCK NGMTGVASYYEVKFTDTNKPNGQIWAGVVGAPVAPGTPRGQRTPERWFVV
Mvan_3343|M.vanbaalenii_PYR-1 PVESAPVFHAAAVPPALPGPVVPVVPAGVPVPVAP---------------
MLBr_02395|M.leprae_Br4923 ATGSSIGKT-----------------------------------------
TH_3264|M.thermoresistible__bu PNVLSPSERTDPLTGQAATPALPVPYPRTGQGGEP---------------
MMAR_3773|M.marinum_M ----KYQVIAEASGVANPDLIHPGEVLTIP--------------------
MUL_3720|M.ulcerans_Agy99 ----KYQVIAEASGVANPDLIHPGEVLTIP--------------------
MSMEG_3662|M.smegmatis_MC2_155 ----KYQQIADASGIANPDLIHPGQVLTIP--------------------
MAB_2373|M.abscessus_ATCC_1997 ----QYQKIADASGIANPDLIQPGQVLTIPE-------------------
Mb1319|M.bovis_AF2122/97 AGQREFRERLSNAGIPHESHEVPGGHVFRPDMFRLDLDGIVARLRPASIG
Rv1288|M.tuberculosis_H37Rv AGQREFRERLSNAGIPHESHEVPGGHVFRPDMFRLDLDGIVARLRPASIG
MAV_1722|M.avium_104 --------VLHSQGIGAWPVCGRRG-------------------------
Mflv_3345|M.gilvum_PYR-GCK WLGTATNPVPQGEAVTLANSIRPWAPPPPPPADPNAPVPPADPNAPPADP
Mvan_3343|M.vanbaalenii_PYR-1 ---VGVPVPVVPTGAPAAVPAPPLGLPAVPLGDAVPGVPFLPATLPIPQD
MLBr_02395|M.leprae_Br4923 --VMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQ
TH_3264|M.thermoresistible__bu ----HLTLPDAITGKPGDPRYPYREPLPAPPPGGPPPGPPAEAPPNEASD
.
MMAR_3773|M.marinum_M ---------------------------------
MUL_3720|M.ulcerans_Agy99 ---------------------------------
MSMEG_3662|M.smegmatis_MC2_155 ---------------------------------
MAB_2373|M.abscessus_ATCC_1997 ---------------------------------
Mb1319|M.bovis_AF2122/97 AAAERAD--------------------------
Rv1288|M.tuberculosis_H37Rv AAAERAD--------------------------
MAV_1722|M.avium_104 ---------------------------------
Mflv_3345|M.gilvum_PYR-GCK NAAPPRPAVGVPVPVDPNTAPGMLPPA------
Mvan_3343|M.vanbaalenii_PYR-1 LVCEGTAWSAGRTAPEGDAAALDAPPGQRRDQW
MLBr_02395|M.leprae_Br4923 TLADKIMTTVCLPI-------------------
TH_3264|M.thermoresistible__bu QPSPQPTLVLAPGEPGAPAPSVPPPPPEAVP--