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ALQPHFEDVQSHYDLSDEFFRLFLDPTQTYSCAYFERDDMTLEEAQLAKIDLSLGKLGLQPGMKLLDIGC GWGATLRRALSRYDVDVVGLTLSKNQQAHVERSFAETDTERSRRVLLQGWEQFDEPVDRIVSIGAFEHFG ADRYDDFFRMAHTALPDDGVMLLHTIVKPSGDEMSQRGLPLTMRKLRFFKFIMDEIFPGGELPYVAQVSE HAQRAGFRVDRVQSLRPHYAKTLDIWAETLRGRKDEAIAVQSEEMYERYMKYLTGCADLFREGYTDVCQF TLVKA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3538 | - | - | 100% (286) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. smegmatis MC2 155 | MSMEG_1351 | - | e-118 | 69.96% (283) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. smegmatis MC2 155 | MSMEG_0902 | - | e-116 | 69.96% (283) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0663c | mmaA2 | 1e-119 | 71.73% (283) | methoxy mycolic acid synthase |
| M. gilvum PYR-GCK | Mflv_3304 | - | 1e-131 | 76.33% (283) | cyclopropane-fatty-acyl-phospholipid synthase |
| M. tuberculosis H37Rv | Rv0644c | mmaA2 | 1e-119 | 72.08% (283) | methoxy mycolic acid synthase |
| M. leprae Br4923 | MLBr_02459 | umaA2 | 1e-116 | 69.47% (285) | Mycolic acid synthase |
| M. abscessus ATCC 19977 | MAB_3881 | - | 1e-103 | 62.54% (283) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. marinum M | MMAR_0979 | mmaA5_1 | 1e-125 | 72.89% (284) | methoxy mycolic acid synthase 5 MmaA5_1 |
| M. avium 104 | MAV_0130 | - | 1e-135 | 79.30% (285) | cyclopropane-fatty-acyl-phospholipid synthase 1 |
| M. thermoresistible (build 8) | TH_3139 | - | 1e-129 | 76.33% (283) | PUTATIVE Cyclopropane-fatty-acyl-phospholipid synthase |
| M. ulcerans Agy99 | MUL_3772 | mmaA5 | 1e-120 | 71.83% (284) | methoxy mycolic acid synthase 5 MmaA5 |
| M. vanbaalenii PYR-1 | Mvan_3025 | - | 1e-128 | 75.62% (283) | cyclopropane-fatty-acyl-phospholipid synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0663c|M.bovis_AF2122/97 ------MVNDLTPHFEDVQAHYDLSDDFFRLFLDPTQTYSCAHFEREDMT
Rv0644c|M.tuberculosis_H37Rv ------MVNDLTPHFEDVQAHYDLSDDFFRLFLDPTQTYSCAHFEREDMT
MUL_3772|M.ulcerans_Agy99 ------MAKHLAPRFDDVQAHYDLSDDFFRLFLDPTQTYSCAYFERDDMT
MMAR_0979|M.marinum_M ------MAKELKPHFDDVQAHYDLSDDFFRLFLDPTQTYSCAYFERDDMT
MLBr_02459|M.leprae_Br4923 ------MSVQLTPHFRNVQAHYDLSDDFFRLFLDPTLTYSCAYFERDDMT
MAV_0130|M.avium_104 MSENTGDAVNLQPHFDDVQAHYDLSDEFFALFLDPTRTYSCAYFERDDMT
TH_3139|M.thermoresistible__bu ----------LTPHFEEVQAHYDLSDDFFRLFLDPSQTYSCAYFERDDMT
Mflv_3304|M.gilvum_PYR-GCK MSDTPNGSADLQPHFDDVQSHYDLSDDFYRLFLDPTQTYSCAYFERDDMT
Mvan_3025|M.vanbaalenii_PYR-1 MPETTSGSADLQPHFEDVQSHYDLSDDFYRLFLDPTQTYSCAYFERDDMT
MSMEG_3538|M.smegmatis_MC2_155 --------MALQPHFEDVQSHYDLSDEFFRLFLDPTQTYSCAYFERDDMT
MAB_3881|M.abscessus_ATCC_1997 -------MSKLTPKFSDVQAHYDLSDDFFALFLDPSRTYSCAYFEPETLT
* *:* :**:******:*: *****: *****:** : :*
Mb0663c|M.bovis_AF2122/97 LEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGLT
Rv0644c|M.tuberculosis_H37Rv LEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGLT
MUL_3772|M.ulcerans_Agy99 LEEAQIAKIDLALGKLGLEPGMTLLDIGCGWGATMRRAIEKYDVNVVGLT
MMAR_0979|M.marinum_M LEEAQIAKIDLALGKLGLEPGMTLLDVGCGWGATMRRAIEKYDVNVVGLT
MLBr_02459|M.leprae_Br4923 LEEAQLAKVDLALGKLKLEPGMTLLDIGCGWGATMKRAIEIYDVNVIGLT
MAV_0130|M.avium_104 LEEAQIAKVDLSLGKLGLQPGMTLLDIGCGWGTTIVRALERYDVNVVGLT
TH_3139|M.thermoresistible__bu LEEAQLAKIDLSLGKLDLKPGMTLLDIGCGWGATIKRAVEKYDVNVVGLT
Mflv_3304|M.gilvum_PYR-GCK LEEAQRAKIDLALGKLGLEPGMTLLDIGCGWGGTLLRALEKYDVNVIGLT
Mvan_3025|M.vanbaalenii_PYR-1 LEEAQIAKIDLSLGKLGLQPGMTLLDIGCGWGATLLRALDKYDVNVIGLT
MSMEG_3538|M.smegmatis_MC2_155 LEEAQLAKIDLSLGKLGLQPGMKLLDIGCGWGATLRRALSRYDVDVVGLT
MAB_3881|M.abscessus_ATCC_1997 LEQAQQAKIDLALGKLNLEPGMTLLDVGCGWGSTMKRALEHYDVNVIGLT
**:** **:**:**** *:***.***:***** *: **: ***:*:***
Mb0663c|M.bovis_AF2122/97 LSKNQAAHVQKSFDEMDTPLDRRVLLAGWEQFNEPVDRIVSIGAFEHFGH
Rv0644c|M.tuberculosis_H37Rv LSKNQAAHVQKSFDEMDTPRDRRVLLAGWEQFNEPVDRIVSIGAFEHFGH
MUL_3772|M.ulcerans_Agy99 LSKNQAAHVQKSFDQLDTARTRRVLLEGWEQFDEPVDRIVSIGAFEHFGH
MMAR_0979|M.marinum_M LSKNQAAHVQKSFDQLDTARTRRVLLEGWEQFDEPVDRIVSIGAFEHFGH
MLBr_02459|M.leprae_Br4923 LSENQAAHVQKTFDELDTPRTRRVLLEGWEKFHEPVDRIVSIGAFEHFGR
MAV_0130|M.avium_104 LSRNQQAHVQRPLDNHPSPRSKRVLLQGWEQFDEKVDRIVSIGAFEHFGR
TH_3139|M.thermoresistible__bu LSRNQQAHVQQVLDEMDSTRSRRVLLQGWEQFREPVDRIVSIGAFEHFGR
Mflv_3304|M.gilvum_PYR-GCK LSRNQQAHVQKVLDEHDSPRSKTVLLQGWEQFDQPVDRIVSIGAFEHFGS
Mvan_3025|M.vanbaalenii_PYR-1 LSRNQQAHVQKRLDAHGSGRSKRVLLAGWEQFDEPVDRIVSIGAFEHFGR
MSMEG_3538|M.smegmatis_MC2_155 LSKNQQAHVERSFAETDTERSRRVLLQGWEQFDEPVDRIVSIGAFEHFGA
MAB_3881|M.abscessus_ATCC_1997 LSKNQFAYVNTLLDSAGSSRNYEVRLAGWEEFEGTVDRIVSIGAFEHFGH
**.** *:*: : : * * ***:* **************
Mb0663c|M.bovis_AF2122/97 DRHADFFARAHKILPPDGVLLLHTITGLTRQQMVDHGLPLTLWLARFLKF
Rv0644c|M.tuberculosis_H37Rv DRHADFFARAHKILPPDGVLLLHTITGLTRQQMVDHGLPLTLWLARFLKF
MUL_3772|M.ulcerans_Agy99 DRYDDFFTLAHNILPSDGVMLLHTITGLTMPQMVENGLPLTLWLARFLKF
MMAR_0979|M.marinum_M DRYDDFFTLAHNILPSDGVMLLHTITGLTFQQATDRGMPLTFEIARFIKF
MLBr_02459|M.leprae_Br4923 QRYARFFKMAHEVLPADSVMLLHTIVRPTFKDARARGMTLTHEIVHFTQF
MAV_0130|M.avium_104 DRYDDFFKMAYAALPDDGVMMLHTIIKPSDEEFAERGLPITMTKLRFMKF
TH_3139|M.thermoresistible__bu DRYEEFFKMAYEVLPADGIMMLHTIIKPSDEEFAARELPITMRYLRFFKF
Mflv_3304|M.gilvum_PYR-GCK DRYDEFFRRAYSVLPDDGVMLLHTIVKPSDEEFAERKLPLTMTKLKFFKF
Mvan_3025|M.vanbaalenii_PYR-1 DRYDEFFKKAYQVLPDGGVMMLHTIIKPTDEEFADRGLKLTMSIVRFSKF
MSMEG_3538|M.smegmatis_MC2_155 DRYDDFFRMAHTALPDDGVMLLHTIVKPSGDEMSQRGLPLTMRKLRFFKF
MAB_3881|M.abscessus_ATCC_1997 ERYDSFFAMAHRVLPSDGKMLLHTIVSHHPDEWKRMGIPLLMSRVRFIYF
:*: ** *: ** .. ::**** : : : :* *
Mb0663c|M.bovis_AF2122/97 IATEIFPGGQPPTIEMVEEQSAKTGFTLTRRQSLQPHYARTLDLWAEALQ
Rv0644c|M.tuberculosis_H37Rv IATEIFPGGQPPTIEMVEEQSAKTGFTLTRRQSLQPHYARTLDLWAEALQ
MUL_3772|M.ulcerans_Agy99 IQTEIFPGGHPPTIEMVEEQSVKPGFTLTRRHSLQLHYAKTLDLWAEALE
MMAR_0979|M.marinum_M IVTEIFPGGRLPSIEKVADHSSKAGFTLTRRQSLQPHYARTLDLWAQALQ
MLBr_02459|M.leprae_Br4923 ILAEIFPGGWLPTVPTVEEHATAAGFKFTRIQSLQLHYAKTLDLWAARLE
MAV_0130|M.avium_104 IMDEIFPGGDLPQAKGVIEHAQRAGFGVQRVQALRPHYARTLDTWAAALR
TH_3139|M.thermoresistible__bu IMDEIFPGGDLPQAKVVEEHATRAGFTVAHTQPLRLHYARTLDHWSSALE
Mflv_3304|M.gilvum_PYR-GCK IMDEIFPGGMLPKVDDVEKHATKASFKVNRIQPLRLHYARTLQIWAASLE
Mvan_3025|M.vanbaalenii_PYR-1 IMDEIFPGGDLPKPTTVAEHATKAGFRLTREQRLREHYAKTLDIWADALR
MSMEG_3538|M.smegmatis_MC2_155 IMDEIFPGGELPYVAQVSEHAQRAGFRVDRVQSLRPHYAKTLDIWAETLR
MAB_3881|M.abscessus_ATCC_1997 IGTEIFPGGRLPSVPMVDKHAALAGFHITRHHSLQPHYARTLDCWATNLA
* ****** * * .:: ..* . : : *: ***:**: *: *
Mb0663c|M.bovis_AF2122/97 EHKSEAIAIQSEEVYERYMKYLTGCAKLFRVGYIDVNQFTLAK-------
Rv0644c|M.tuberculosis_H37Rv EHKSEAIAIQSEEVYERYMKYLTGCAKLFRVGYIDVNQFTLAK-------
MUL_3772|M.ulcerans_Agy99 VRKDEAIKIQSDEVYERYMRYLTGCSKLFQEGYVDVNQFTLQKAR-----
MMAR_0979|M.marinum_M ARRDEAIEVQSEEVYERYMKYLTGCADGFRVGYIDVNQFTLEKS------
MLBr_02459|M.leprae_Br4923 ANKNKAIAIQSEEVYDRYMKYLTGCAKLFRDGYTDVDQFTLEKQPATARR
MAV_0130|M.avium_104 ARRDEAIAIQSEEVYDRYMKYLTGCADLFREGYTDVAQFTLTKG------
TH_3139|M.thermoresistible__bu ARKDEAIAIQSEEVYERYMKYLTGCADLFRKGYTDVCQFTLKK-------
Mflv_3304|M.gilvum_PYR-GCK SRRDDAIAIQSEEVYDRYMKYLTGCAELFTEGYTDVCQFTLAK-------
Mvan_3025|M.vanbaalenii_PYR-1 KREDDAVAIQSREDYDRYMKYLTGCADLFRDGYTDICQFTLEK-------
MSMEG_3538|M.smegmatis_MC2_155 GRKDEAIAVQSEEMYERYMKYLTGCADLFREGYTDVCQFTLVKA------
MAB_3881|M.abscessus_ATCC_1997 AHEDEAISVQSQEVYDRYIKYLTGCAEGFREGWIDVVQFTCEK-------
....*: :** * *:**::*****:. * *: *: *** *
Mb0663c|M.bovis_AF2122/97 -
Rv0644c|M.tuberculosis_H37Rv -
MUL_3772|M.ulcerans_Agy99 -
MMAR_0979|M.marinum_M -
MLBr_02459|M.leprae_Br4923 H
MAV_0130|M.avium_104 -
TH_3139|M.thermoresistible__bu -
Mflv_3304|M.gilvum_PYR-GCK -
Mvan_3025|M.vanbaalenii_PYR-1 -
MSMEG_3538|M.smegmatis_MC2_155 -
MAB_3881|M.abscessus_ATCC_1997 -