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MSRRTAGLDVAVSHAKAFLAQLDDRPVAARGDASAVRQLLGAPLPETGEDPAAVIEGLAVGAEPGLVAGA GPRHFGFVIGGSLPAALGADWLVSAWDQCAAFHALSPAATAIEEITAGWVLDLLGLPAECGVGFVTGAQA ANTTGLAAARHAVLARAGWDVSRDGLIGAPRIRVVCGGQAHTTVYAALRLLGLGEASAARVAVDDQGRMR PEALAETLAAGTGPAIVCAQAGNVATGAFDDLDVIADICSDHDAWLHVDGAFGLWAAAAPSTRHLTAGVA RADSWAVDAHKWLNVPYDCAMAIVRDADAHVAAMSLAGPYLIVDPGQRDNTNFVPESSRRARAVPVYAAL RSLGRAGLADLIERNCAQARRVARLLAEIPGAQILNDVVLNQVLVRLPGGDEATRRAVAAIQADGTCWLG GTTWNDEFVLRLSFTNWATSDDDVDRSAAAITDAVASSRTSQQPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3506 | - | - | 100% (465) | putative amino acid decarboxylase, pyridoxal-dependent protein |
| M. smegmatis MC2 155 | MSMEG_6591 | - | 8e-05 | 27.92% (265) | aminotransferase, class V family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00354 | ilvX | 8e-05 | 25.86% (290) | hypothetical protein MLBr_00354 |
| M. abscessus ATCC 19977 | MAB_1685 | - | 4e-37 | 33.33% (330) | putative decarboxylase |
| M. marinum M | MMAR_0167 | - | 3e-37 | 32.68% (355) | glutamate decarboxylase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2178 | - | 0.0 | 74.62% (457) | putative amino acid decarboxylase, Pyridoxal-dependent protein |
| M. ulcerans Agy99 | MUL_4929 | - | 2e-37 | 32.68% (355) | glutamate decarboxylase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3506|M.smegmatis_MC2_155 MSRRTAG----------LDVAVSHAKAFLAQLDDRPVAARGDASAVRQLL
TH_2178|M.thermoresistible__bu MSDRTAG----------LTTAAEQAHRFLTGLDDRPVGARADAAAVRGLL
MMAR_0167|M.marinum_M MSRDVS-----DFAGEFVSGSGTAAYRDAITLASGLVANALEAADAPGLV
MUL_4929|M.ulcerans_Agy99 MSRDVS-----DFAGEFVSGSGTAAYCDAITLASGLVANALEAADAPGLV
MAB_1685|M.abscessus_ATCC_1997 MTAHQSPFVQSPFVSDFLTGDSAHTYREAVALAAERASVTLGGATAPGLV
MLBr_00354|M.leprae_Br4923 MNGAQAMIS------TLVDGGVDVCFANPGTSEMHFVAALDTVAGMRGVL
*. : : .. : ::
MSMEG_3506|M.smegmatis_MC2_155 G--APLPETGE--------DPAAVIEGLAVGAEPGLVAG-----AGPRHF
TH_2178|M.thermoresistible__bu D--GPLPEHGE--------DPDRVITALVDGAEPGLVAG-----AGPRHF
MMAR_0167|M.marinum_M DGYSLLKELADK---PRLDTVAGVGLPAALEEAVGLMAGHSAVVTHPAYL
MUL_4929|M.ulcerans_Agy99 DGYSLLKELADK---PRLDTVAGVGLPAALEEAVGLMAGHSAVVTHPAYL
MAB_1685|M.abscessus_ATCC_1997 DGYSALKRDAER---LDLDDPDGVGLSRALDEATGLLAEKSVVVTHPAYL
MLBr_00354|M.leprae_Br4923 TLFEGVATGAADGYARIAGRPAVVLLHLGPGLGNGLANLHNARRARVPMV
: . * ** : .
MSMEG_3506|M.smegmatis_MC2_155 GFVIGGSLPAALGADWLVSAWDQCAAFHA---LSPAATAIEEITAGWVLD
TH_2178|M.thermoresistible__bu GFVIGGVLPAALAADWLVSAWDQCAAFHS---LSPAAAAIEEITAAWILD
MMAR_0167|M.marinum_M AHLHCPPTVASLSAEVLISAFNQSLDSFD---QAPAATAIEQRVVEHLCA
MUL_4929|M.ulcerans_Agy99 AHLHCPPTVASLSAEVLISAFNQSLDSFD---QAPAATAIEQRVVEHLCA
MAB_1685|M.abscessus_ATCC_1997 AHLHCPPALPSLAAEVLISAFNQSMDSFD---QAPAATAIEQQVVEYLCT
MLBr_00354|M.leprae_Br4923 VVVGDHATYHKKYDAPLESDIDALAGTVSGWLHRTMDTADVGVDAAEAIS
: * * : . :* .
MSMEG_3506|M.smegmatis_MC2_155 LLGLPAECGVGFVTGAQAANTTGLAAAR-HAVLARAGWDVSRD--GLIG-
TH_2178|M.thermoresistible__bu LLGLPDTASVGFVTGGQGANTTCLAAAR-HAALAKVGWNVERD--GLIG-
MMAR_0167|M.marinum_M RIGYGTDADGTFTSGGTQSNLHALLMARDVFAQRTLGLDVGTA--GLPAA
MUL_4929|M.ulcerans_Agy99 RIGYGTDADGTFTSGGTQSNLHALLMARDVFAQRTLGLDVGTA--GLPAA
MAB_1685|M.abscessus_ATCC_1997 RMGYGRESDGTFTSGGTQSNLQALLLARDLFAR-KAGWDIAGL--GLPPE
MLBr_00354|M.leprae_Br4923 ASLVGSQISTLILPADVSWSDGAIPAASVSDQPASAGVDVGAVRTALESG
. : .. . : * * :: .*
MSMEG_3506|M.smegmatis_MC2_155 APRIRVVCGGQAHTTVYAALRLLGLGEAS-----AARVAVDDQGRMRPEA
TH_2178|M.thermoresistible__bu APPLRVVCGEQAHVTIDTALRLLGLGDST-----SVRVPADDQGRMDPQA
MMAR_0167|M.marinum_M ARSWRLLCTRQAHFSARQALRILGLGADA-----VIEVPTDDAGRLCVEA
MUL_4929|M.ulcerans_Agy99 ARSWRLLCTRQAHFSARQALRILGLGADA-----VIEVPTDDAGRLCVEA
MAB_1685|M.abscessus_ATCC_1997 SGTWRVLCTRQTHFSVQQALRLLGLGTSA-----IIEVPTDDAGRLRAET
MLBr_00354|M.leprae_Br4923 EPTVILIGADATGWSGLAAVARIGAATGARWFCETFPARLERGAGVPAVE
:: : : *: :* . : . : . :
MSMEG_3506|M.smegmatis_MC2_155 LAETLAAGTGP----AIVCAQAGNVATGAFDDLDVIADICSDHDAWLHVD
TH_2178|M.thermoresistible__bu LQRILASSSEP----TIVCAQAGNVSTGAFDDFGPIADACDEHGAWLHID
MMAR_0167|M.marinum_M LAGCIAESQARGTPVFGLFLTAGTTDYGAIDPLEPAIKIARQHGVWAHVD
MUL_4929|M.ulcerans_Agy99 LAGCIAESQARGTPVFGLFLTAGTTDYGAIDPLEPAIKIARQHGVWAHVD
MAB_1685|M.abscessus_ATCC_1997 LAGILRDADHAGTPVFALVLTAGTTDFGAIDPLEEATAIARSHGIWVHVD
MLBr_00354|M.leprae_Br4923 RLAYFAEVAAAQLDGAKHLVLAGAQSPVSFFAYPGMPSDLVPAGCEVHVL
: ** :: . *:
MSMEG_3506|M.smegmatis_MC2_155 GAFGLWAAAAPSTRHLTAGVARADSWAVDAHKWLNVPYD------CAMAI
TH_2178|M.thermoresistible__bu GAFGLWAAAAPGTRHLTRGVERADSWAVDAHKWLNVPYD------AAMAI
MMAR_0167|M.marinum_M ACVGGCLAFSAQHRHLLRGIELADSVAVDFHKLLFQAIS------CSALL
MUL_4929|M.ulcerans_Agy99 ACVGGCLAFSAQHRHLLRGIELADSVAVDFHKLLFQAIS------CSALL
MAB_1685|M.abscessus_ATCC_1997 ACAGGCLIFSAQHRQLLRGIEQADSVAIDFHKLLFQAIS------CSALL
MLBr_00354|M.leprae_Br4923 AEHGGAAYALNALADEVASGTAAPVVAASRPQLPSGPLTSGAAANVIGAL
. * . . * * . : . :
MSMEG_3506|M.smegmatis_MC2_155 VRDADAHVAAMSLAGPYLIVDPGQRDNTNFVPE---SSRRARAVPVYAAL
TH_2178|M.thermoresistible__bu VADSEAHLAAMSLAGPYLVTDPVHRDSTNYVPE---SSRRSRAVPVYAAL
MMAR_0167|M.marinum_M VRDAESFRVSAGHADYLNPADDVEHDVVNLVGKSLQTTRRFDALKIFLTL
MUL_4929|M.ulcerans_Agy99 VRDAESFRVSAGHADYLNPADDVEHDVVNLVGKSLQTTRRFDALKIFLTL
MAB_1685|M.abscessus_ATCC_1997 VRNRESFGVLAAHADYLNPASDAEHDVLNLVGNSLQTTRRFDALKVLVTL
MLBr_00354|M.leprae_Br4923 LPERAIVVDESNTSGVLLAAATAGAPAHDWLTLTGGAIGHGIPASVGAAV
: : :. . : : : : . : ::
MSMEG_3506|M.smegmatis_MC2_155 RSLGRAGLADLIERNCAQARRVARLLAEIPGAQILNDVVLNQVLVRLP--
TH_2178|M.thermoresistible__bu RSLGRSGLAELIERNCAQARRMARRLQDIPGAKIRNDVVLNQVLLRLP--
MMAR_0167|M.marinum_M RALGERRIGAMIDATCAAAAAAGRAVSDHPHLTLCAPVAVNTVVLRWRHP
MUL_4929|M.ulcerans_Agy99 RALGERRIGAMIDATCAAAAAAGRAVSDHPHLTLCAPVAVNTVVLRWRHP
MAB_1685|M.abscessus_ATCC_1997 RAVGQRQVAAMIDATVAAAAAAAQVAAEHPDLELVAPVCTNTVVLRWRRP
MLBr_00354|M.leprae_Br4923 AAPDRP--VLCLESDGSAMYTISGLWTQARENLDVTTIIYNNGAYNILRI
: .. :: : . : : * .
MSMEG_3506|M.smegmatis_MC2_155 -----GGDEATRRAVAAIQADGTCWLGGTTWNDEFVLRLSFTNWATSDDD
TH_2178|M.thermoresistible__bu -----GGDDANRAAVAAVQRDGTCWLGGTTWRGEYVVRLSFSNWSTTDDD
MMAR_0167|M.marinum_M ELTEQKCDAVNSAIRSSLARCGLALVGRSRAAGHQAIKLTFVNPLITADL
MUL_4929|M.ulcerans_Agy99 ELTEQKCDAVNSAIRSSLARCGLALVGRSRAAGHQAIKLTFVNPLITADL
MAB_1685|M.abscessus_ATCC_1997 EATRDARDDVNDAVRAELAHSGRAIVGRSGAAGAQAIKLTFVNPLVTTSM
MLBr_00354|M.leprae_Br4923 ELQRMGAGSTPGPKALSLLDLSSPTMDFVKIAEGMGVSARRVN--TTEGL
. . : . :. : * : .
MSMEG_3506|M.smegmatis_MC2_155 VDRSAAAITDAVASSRTSQQPG----
TH_2178|M.thermoresistible__bu IDRSAEAIAVAARSVAAAG-------
MMAR_0167|M.marinum_M ATGVIADVSRRGNEIACLPDDLAAQA
MUL_4929|M.ulcerans_Agy99 ATGVIADVSRRGNEIAGLPDDLAAQA
MAB_1685|M.abscessus_ATCC_1997 AGAMVSDIAAHGNRIWRARTPEVSAV
MLBr_00354|M.leprae_Br4923 ADALRLAFTEPGPHLIDTVVPSIVG-
.: