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M. thermoresistible (build 8) TH_2178 (-)

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2178	-	-	100% (463)	putative amino acid decarboxylase, Pyridoxal-dependent protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_1685	-	1e-36	29.28% (461)	putative decarboxylase
M. marinum M	MMAR_0167	-	1e-40	30.39% (487)	glutamate decarboxylase
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_3506	-	0.0	74.62% (457)	putative amino acid decarboxylase, pyridoxal-dependent protein
M. ulcerans Agy99	MUL_4929	-	3e-40	30.60% (464)	glutamate decarboxylase
M. vanbaalenii PYR-1	-	-	-	-	-

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0167|M.marinum_M               MSRDVS-----DFAGEFVSGSGTAAYRDAITLASGLVANALEAADAPGLV
MUL_4929|M.ulcerans_Agy99           MSRDVS-----DFAGEFVSGSGTAAYCDAITLASGLVANALEAADAPGLV
MAB_1685|M.abscessus_ATCC_1997      MTAHQSPFVQSPFVSDFLTGDSAHTYREAVALAAERASVTLGGATAPGLV
TH_2178|M.thermoresistible__bu      MSDRTAG----------LTTAAEQAHRFLTGLDDRPVGARADAAAVRGLL
MSMEG_3506|M.smegmatis_MC2_155      MSRRTAG----------LDVAVSHAKAFLAQLDDRPVAARGDASAVRQLL
                                    *:   :           :      :      *    ..    .: .  *:

MMAR_0167|M.marinum_M               DGYSLLKELADKPRLDTVAGVGLPAALEEAVGLMAGHSAVVTHPAYLAHL
MUL_4929|M.ulcerans_Agy99           DGYSLLKELADKPRLDTVAGVGLPAALEEAVGLMAGHSAVVTHPAYLAHL
MAB_1685|M.abscessus_ATCC_1997      DGYSALKRDAERLDLDDPDGVGLSRALDEATGLLAEKSVVVTHPAYLAHL
TH_2178|M.thermoresistible__bu      D--GPLPEHGE-----DPDRVITALVDGAEPGLVAG-----AGPRHFGFV
MSMEG_3506|M.smegmatis_MC2_155      G--APLPETGE-----DPAAVIEGLAVGAEPGLVAG-----AGPRHFGFV
                                    .  . * . .:         *    .     **:*      : * ::..:

MMAR_0167|M.marinum_M               HCPPTVASLSAEVLISAFNQSLDSFDQAPAATAIEQRVVEHLCARIGYGT
MUL_4929|M.ulcerans_Agy99           HCPPTVASLSAEVLISAFNQSLDSFDQAPAATAIEQRVVEHLCARIGYGT
MAB_1685|M.abscessus_ATCC_1997      HCPPALPSLAAEVLISAFNQSMDSFDQAPAATAIEQQVVEYLCTRMGYGR
TH_2178|M.thermoresistible__bu      IGGVLPAALAADWLVSAWDQCAAFHSLSPAAAAIEEITAAWILDLLGLPD
MSMEG_3506|M.smegmatis_MC2_155      IGGSLPAALGADWLVSAWDQCAAFHALSPAATAIEEITAGWVLDLLGLPA
                                          .:*.*: *:**::*.   .  :***:***: ..  :   :*   

MMAR_0167|M.marinum_M               DADGTFTSGGTQSNLHALLMARDVFAQRTLGLDVGTAGLPAAARSWRLLC
MUL_4929|M.ulcerans_Agy99           DADGTFTSGGTQSNLHALLMARDVFAQRTLGLDVGTAGLPAAARSWRLLC
MAB_1685|M.abscessus_ATCC_1997      ESDGTFTSGGTQSNLQALLLARDLFAR-KAGWDIAGLGLPPESGTWRVLC
TH_2178|M.thermoresistible__bu      TASVGFVTGGQGANTTCLAAARHAALA-KVGWNVERDGLIG-APPLRVVC
MSMEG_3506|M.smegmatis_MC2_155      ECGVGFVTGAQAANTTGLAAARHAVLA-RAGWDVSRDGLIG-APRIRVVC
                                     ..  *.:*.  :*   *  **.       * ::   **   :   *::*

MMAR_0167|M.marinum_M               TRQAHFSARQALRILGLGADAVIEVPTDDAGRLCVEALAGCIAESQARGT
MUL_4929|M.ulcerans_Agy99           TRQAHFSARQALRILGLGADAVIEVPTDDAGRLCVEALAGCIAESQARGT
MAB_1685|M.abscessus_ATCC_1997      TRQTHFSVQQALRLLGLGTSAIIEVPTDDAGRLRAETLAGILRDADHAGT
TH_2178|M.thermoresistible__bu      GEQAHVTIDTALRLLGLGDSTSVRVPADDQGRMDPQALQRILASSSEP--
MSMEG_3506|M.smegmatis_MC2_155      GGQAHTTVYAALRLLGLGEASAARVAVDDQGRMRPEALAETLAAGTGP--
                                      *:* :   ***:****  :  .*..** **:  ::*   :  .     

MMAR_0167|M.marinum_M               PVFGLFLTAGTTDYGAIDPLEPAIKIARQHGVWAHVDACVGGCLAFSAQH
MUL_4929|M.ulcerans_Agy99           PVFGLFLTAGTTDYGAIDPLEPAIKIARQHGVWAHVDACVGGCLAFSAQH
MAB_1685|M.abscessus_ATCC_1997      PVFALVLTAGTTDFGAIDPLEEATAIARSHGIWVHVDACAGGCLIFSAQH
TH_2178|M.thermoresistible__bu      --TIVCAQAGNVSTGAFDDFGPIADACDEHGAWLHIDGAFGLWAAAAPGT
MSMEG_3506|M.smegmatis_MC2_155      --AIVCAQAGNVATGAFDDLDVIADICSDHDAWLHVDGAFGLWAAAAPST
                                        :   **..  **:* :      . .*. * *:*.. *     :.  

MMAR_0167|M.marinum_M               RHLLRGIELADSVAVDFHKLLFQAISCSALLVRDAESFRVSAGHADYLNP
MUL_4929|M.ulcerans_Agy99           RHLLRGIELADSVAVDFHKLLFQAISCSALLVRDAESFRVSAGHADYLNP
MAB_1685|M.abscessus_ATCC_1997      RQLLRGIEQADSVAIDFHKLLFQAISCSALLVRNRESFGVLAAHADYLNP
TH_2178|M.thermoresistible__bu      RHLTRGVERADSWAVDAHKWLNVPYDAAMAIVADSEAHLAAMSLAGPYLV
MSMEG_3506|M.smegmatis_MC2_155      RHLTAGVARADSWAVDAHKWLNVPYDCAMAIVRDADAHVAAMSLAGPYLI
                                    *:*  *:  *** *:* ** *  . ..:  :* : ::. .  . *.    

MMAR_0167|M.marinum_M               ADDVEHDVVNLVGKSLQTTRRFDALKIFLTLRALGERRIGAMIDATCAAA
MUL_4929|M.ulcerans_Agy99           ADDVEHDVVNLVGKSLQTTRRFDALKIFLTLRALGERRIGAMIDATCAAA
MAB_1685|M.abscessus_ATCC_1997      ASDAEHDVLNLVGNSLQTTRRFDALKVLVTLRAVGQRQVAAMIDATVAAA
TH_2178|M.thermoresistible__bu      TDPVHRDSTNYVPE---SSRRSRAVPVYAALRSLGRSGLAELIERNCAQA
MSMEG_3506|M.smegmatis_MC2_155      VDPGQRDNTNFVPE---SSRRARAVPVYAALRSLGRAGLADLIERNCAQA
                                    ..  .:*  * * :   ::**  *: :  :**::*.  :. :*: . * *

MMAR_0167|M.marinum_M               AAAGRAVSDHPHLTLCAPVAVNTVVLRWRHPELTEQKCDAVNSAIRSSLA
MUL_4929|M.ulcerans_Agy99           AAAGRAVSDHPHLTLCAPVAVNTVVLRWRHPELTEQKCDAVNSAIRSSLA
MAB_1685|M.abscessus_ATCC_1997      AAAAQVAAEHPDLELVAPVCTNTVVLRWRRPEATRDARDDVNDAVRAELA
TH_2178|M.thermoresistible__bu      RRMARRLQDIPGAKIRNDVVLNQVLLRLP-------GGDDANRAAVAAVQ
MSMEG_3506|M.smegmatis_MC2_155      RRVARLLAEIPGAQILNDVVLNQVLVRLP-------GGDEATRRAVAAIQ
                                       .:   : *   :   *  * *::*           * ..    : : 

MMAR_0167|M.marinum_M               RCGLALVGRSRAAGHQAIKLTFVNPLITADLATGVIADVSRRGNEIACLP
MUL_4929|M.ulcerans_Agy99           RCGLALVGRSRAAGHQAIKLTFVNPLITADLATGVIADVSRRGNEIAGLP
MAB_1685|M.abscessus_ATCC_1997      HSGRAIVGRSGAAGAQAIKLTFVNPLVTTSMAGAMVSDIAAHGNRIWRAR
TH_2178|M.thermoresistible__bu      RDGTCWLGGTTWRGEYVVRLSFSNWSTTDDDIDRSAEAIAVAARSVAAAG
MSMEG_3506|M.smegmatis_MC2_155      ADGTCWLGGTTWNDEFVLRLSFTNWATSDDDVDRSAAAITDAVASSRTSQ
                                      * . :* :   .  .::*:* *   : .        ::          

MMAR_0167|M.marinum_M               DDLAAQA
MUL_4929|M.ulcerans_Agy99           DDLAAQA
MAB_1685|M.abscessus_ATCC_1997      TPEVSAV
TH_2178|M.thermoresistible__bu      -------
MSMEG_3506|M.smegmatis_MC2_155      QPG----