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MALRALVFDVFGTLVDWRSGVADAFRSAGVVGDPDDLADAWRARYRPILDEVNDGLRPWGNFDELHLATL QDVLSERDIALSPDQLTSLVHAWHRLDPWPDVRDGLELLRSNFLIAPLSNGHVRLVVDLARHGDLRFDCI LSAELAHAYKPAPETYLTAAHLLDVDPSEVMLVAAHPSDLAGARAAGLRTAFIDRPLEHGPATPKRSDRK ADVSAADLHELARLLGDEGKA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3450 | dehII | - | 100% (231) | haloacid dehalogenase, type II |
| M. smegmatis MC2 155 | MSMEG_0115 | dehII | 1e-10 | 27.63% (228) | haloacid dehalogenase, type II |
| M. smegmatis MC2 155 | MSMEG_4059 | - | 2e-08 | 25.13% (195) | haloacid dehalogenase, type II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3410 | - | 5e-06 | 25.98% (254) | hypothetical protein Mb3410 |
| M. gilvum PYR-GCK | Mflv_0739 | - | 1e-56 | 49.14% (232) | haloacid dehalogenase, type II |
| M. tuberculosis H37Rv | Rv3376 | - | 5e-06 | 25.98% (254) | hypothetical protein Rv3376 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2863 | - | 1e-28 | 35.27% (207) | HAD-superfamily hydrolase YfnB |
| M. marinum M | MMAR_3371 | - | 3e-35 | 40.34% (233) | hypothetical protein MMAR_3371 |
| M. avium 104 | MAV_2690 | dehII | 1e-35 | 37.66% (231) | haloacid dehalogenase, type II |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1268 | - | 5e-33 | 42.00% (200) | hypothetical protein MUL_1268 |
| M. vanbaalenii PYR-1 | Mvan_0108 | - | 5e-58 | 50.43% (232) | haloacid dehalogenase, type II |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0739|M.gilvum_PYR-GCK ------MPIRALAFDVFGTVVDWRSSIIAELSEFGREHGVDADWSRFADD
Mvan_0108|M.vanbaalenii_PYR-1 MREEQTVVIRALAFDVFGTVVDWRSSVIRELGDFGRRNGVSADWPRFADD
MSMEG_3450|M.smegmatis_MC2_155 ------MALRALVFDVFGTLVDWRSGVADAF----RSAGVVGDPDDLADA
MMAR_3371|M.marinum_M ----MSLMVTALLFDVQGTATDFHSTVCDEARRISAGRHPDADWPELVRR
MUL_1268|M.ulcerans_Agy99 -----------MLFDVQGTATDFHSTVCDEARRISAGRHPDADWPELVRR
MAV_2690|M.avium_104 MTHSARFAPKALLFDVQGTVTDFHSTVCSEAQRICGSRNQNVDWSDFVNS
MAB_2863|M.abscessus_ATCC_1997 ------MRYKAYLFDVQGTLLDFFEPVS----RAVAEYSPDVDAAAFTRA
Mb3410|M.bovis_AF2122/97 ------MSISAVVFDRDGVLTSFDWTRAEED----VRRITGLPLEEIERR
Rv3376|M.tuberculosis_H37Rv ------MSISAVVFDRDGVLTSFDWTRAEED----VRRITGLPLEEIERR
** *. .: :
Mflv_0739|M.gilvum_PYR-GCK WRAGYVPAMDRVRRGELPWTRIDDLHRGRLVELLDQAAIT-VSDTDIDHL
Mvan_0108|M.vanbaalenii_PYR-1 WRAGYVPAMDRVRRGELPWTRLDDLHRGRLVELLEGTGIT-VSDSEIDEL
MSMEG_3450|M.smegmatis_MC2_155 WRARYRPILDEVNDGLRPWGNFDELHLATLQDVLSERDIA-LSPDQLTSL
MMAR_3371|M.marinum_M WRAGYFSALDASSGGHGGWVSVYSVYRQVLDAVLDGCGVTGLSAAERDEL
MUL_1268|M.ulcerans_Agy99 WRAGYFSALDASSGGHGGWVSVYSVYRQVLDAVLDGCGVTGLSAAERDEL
MAV_2690|M.avium_104 WRAAYFSCLEAAKPDRDNWITVHSVYRSSLESLLAEYSITDLTAAERDEL
MAB_2863|M.abscessus_ATCC_1997 WRADYFERVSSLTQSADHWTRVQDLYAAGFADVCQTFGLPCPDTATAEDV
Mb3410|M.bovis_AF2122/97 WGG-WLNGLTID----DAFVETQPIS-EFLSSLARELELG--SKARDELV
Rv3376|M.tuberculosis_H37Rv WGG-WLNGLTID----DAFVETQPIS-EFLSSLARELELG--SKARDELV
* . : : : : : : : :
Mflv_0739|M.gilvum_PYR-GCK NRAWHRLDP-WPDSVAGLTRLKQR-FLITTLSNGNVSLLTD-MAKRAGLP
Mvan_0108|M.vanbaalenii_PYR-1 NRAWHRLDP-WPDAVAGLTRLKRR-FVITTLSNGNVSLLTN-MAKRAGLP
MSMEG_3450|M.smegmatis_MC2_155 VHAWHRLDP-WPDVRDGLELLRSN-FLIAPLSNGHVRLVVD-LARHGDLR
MMAR_3371|M.marinum_M TLAWQRLRP-WPDVVAGLTRLKTK-FTLATLSNADVSAVVN-ISKRAALP
MUL_1268|M.ulcerans_Agy99 TLAWQRLRP-WPDVVAGLTRLKTK-FTLATLSNADVSAVVN-ISKRAALP
MAV_2690|M.avium_104 TLAWQRLVP-WPDVLPGLTRLKKK-FIIATLSNADVSALIN-IAKRGGLP
MAB_2863|M.abscessus_ATCC_1997 ASSWQRLVP-WPDVPAGLAALRMR-AVVATLSNTDMATMVN-LFKRLDIS
Mb3410|M.bovis_AF2122/97 RLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLVSARSLLQCAALH
Rv3376|M.tuberculosis_H37Rv RLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLVSARSLLQCAALH
: : :** .* : . : *:* : : : :
Mflv_0739|M.gilvum_PYR-GCK --WDCVLSAEIFGHYKPDREAYLGTAHILDVAPGELMMVAAHPSDLRAAR
Mvan_0108|M.vanbaalenii_PYR-1 --WDCVLSAEIFGHYKPDREAYLGCAEILDVAPGELMLVAAHPSDLRGAR
MSMEG_3450|M.smegmatis_MC2_155 --FDCILSAELAHAYKPAPETYLTAAHLLDVDPSEVMLVAAHPSDLAGAR
MMAR_3371|M.marinum_M --WDAIFAAEMAGVFKPDPAAYRMAVGYLGCEPAEVMMVASHKYDLRAAA
MUL_1268|M.ulcerans_Agy99 --WDAIFAAEMAGVFKPDPAAYRMAVGYLGCEPAEVMMVASHKYDLRAAA
MAV_2690|M.avium_104 --WDAVFAAEMAGVFKPDPAIYHMAARYLGLAPRQIMMVASHKYDIRAAA
MAB_2863|M.abscessus_ATCC_1997 --WDAIFTAEVFGRFKPDPSVYRGALRYLGVEPYEAAMVAAHPYDLRAAR
Mb3410|M.bovis_AF2122/97 DLVDVVLSSQMIGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADWVEGAR
Rv3376|M.tuberculosis_H37Rv DLVDVVLSSQMIGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADWVEGAR
* :::::: ** * *. . . :. : .*
Mflv_0739|M.gilvum_PYR-GCK DAGLVTAYVHRPLEQG--PDRTPERPGHDEFDITASDFGD---FADQLGA
Mvan_0108|M.vanbaalenii_PYR-1 RAGLATAFVHRPLEQG--PDRAPARPADGEFDVMADDFHD---LADRLGV
MSMEG_3450|M.smegmatis_MC2_155 AAGLRTAFIDRPLEHG--P-ATPKR-SDRKADVSAADLHE---LARLLGD
MMAR_3371|M.marinum_M RLGLRTAFVARPLEFG--IGGAADATYADEFDINAADFLD---LAGQLGC
MUL_1268|M.ulcerans_Agy99 RLGLRTAFVARPLEFGSVVRPMQPMPMSSTSTPQTSSILPGNSVADRCGV
MAV_2690|M.avium_104 SLGFQTAFVTRPFEFG--PLGLADTAYDDAFDVNAADLLD---LATQLSC
MAB_2863|M.abscessus_ATCC_1997 QLGMGTIFVSRPHEYG--DPVLAHTDPDEEFDQRVTAIGE---LS-----
Mb3410|M.bovis_AF2122/97 CAGMRAYLVDRSGQTR--DGVVRDLSSLGAILDGAGP-------------
Rv3376|M.tuberculosis_H37Rv CAGMRAYLVDRSGQTR--DGVVRDLSSLGAILDGAGP-------------
*: : : *. : .
Mflv_0739|M.gilvum_PYR-GCK ----------
Mvan_0108|M.vanbaalenii_PYR-1 ----------
MSMEG_3450|M.smegmatis_MC2_155 EGKA------
MMAR_3371|M.marinum_M ----------
MUL_1268|M.ulcerans_Agy99 ETSFTRTEFG
MAV_2690|M.avium_104 ----------
MAB_2863|M.abscessus_ATCC_1997 ----------
Mb3410|M.bovis_AF2122/97 ----------
Rv3376|M.tuberculosis_H37Rv ----------