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M. avium 104 MAV_2690 (dehII)

annotation: haloacid dehalogenase, type II
coordinates: 2724520 - 2725242
length: 240

THSARFAPKALLFDVQGTVTDFHSTVCSEAQRICGSRNQNVDWSDFVNSWRAAYFSCLEAAKPDRDNWIT
VHSVYRSSLESLLAEYSITDLTAAERDELTLAWQRLVPWPDVLPGLTRLKKKFIIATLSNADVSALINIA
KRGGLPWDAVFAAEMAGVFKPDPAIYHMAARYLGLAPRQIMMVASHKYDIRAAASLGFQTAFVTRPFEFG
PLGLADTAYDDAFDVNAADLLDLATQLSC*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2690dehII-100% (240)haloacid dehalogenase, type II
M. avium 104MAV_1053-5e-0629.82% (114) hypothetical protein MAV_1053

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0739-4e-4942.79% (229) haloacid dehalogenase, type II
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2863-7e-4840.71% (226) HAD-superfamily hydrolase YfnB
M. marinum MMMAR_3371-2e-8766.09% (230) hypothetical protein MMAR_3371
M. smegmatis MC2 155MSMEG_3450dehII1e-3537.66% (231) haloacid dehalogenase, type II
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1268-4e-7766.50% (200) hypothetical protein MUL_1268
M. vanbaalenii PYR-1Mvan_0108-5e-4844.10% (229) haloacid dehalogenase, type II

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3371|M.marinum_M               ----MSLMVTALLFDVQGTATDFHSTVCDEARRISAGRHPDADWPELVRR
MUL_1268|M.ulcerans_Agy99           -----------MLFDVQGTATDFHSTVCDEARRISAGRHPDADWPELVRR
MAV_2690|M.avium_104                MTHSARFAPKALLFDVQGTVTDFHSTVCSEAQRICGSRNQNVDWSDFVNS
MAB_2863|M.abscessus_ATCC_1997      ------MRYKAYLFDVQGTLLDFFEPVS----RAVAEYSPDVDAAAFTRA
Mflv_0739|M.gilvum_PYR-GCK          ------MPIRALAFDVFGTVVDWRSSIIAELSEFGREHGVDADWSRFADD
Mvan_0108|M.vanbaalenii_PYR-1       MREEQTVVIRALAFDVFGTVVDWRSSVIRELGDFGRRNGVSADWPRFADD
MSMEG_3450|M.smegmatis_MC2_155      ------MALRALVFDVFGTLVDWRSGVADAF----RSAGVVGDPDDLADA
                                                 *** **  *: . :               *   :.  

MMAR_3371|M.marinum_M               WRAGYFSALDASSGGHGGWVSVYSVYRQVLDAVLDGCGVTGLSAAERDEL
MUL_1268|M.ulcerans_Agy99           WRAGYFSALDASSGGHGGWVSVYSVYRQVLDAVLDGCGVTGLSAAERDEL
MAV_2690|M.avium_104                WRAAYFSCLEAAKPDRDNWITVHSVYRSSLESLLAEYSITDLTAAERDEL
MAB_2863|M.abscessus_ATCC_1997      WRADYFERVSSLTQSADHWTRVQDLYAAGFADVCQTFGLPCPDTATAEDV
Mflv_0739|M.gilvum_PYR-GCK          WRAGYVPAMDRVRRGELPWTRIDDLHRGRLVELLDQAAIT-VSDTDIDHL
Mvan_0108|M.vanbaalenii_PYR-1       WRAGYVPAMDRVRRGELPWTRLDDLHRGRLVELLEGTGIT-VSDSEIDEL
MSMEG_3450|M.smegmatis_MC2_155      WRARYRPILDEVNDGLRPWGNFDELHLATLQDVLSERDIA-LSPDQLTSL
                                    *** *   :.    .   *  . .::   :  :     :.         :

MMAR_3371|M.marinum_M               TLAWQRLRPWPDVVAGLTRLKTKFTLATLSNADVSAVVNISKRAALPWDA
MUL_1268|M.ulcerans_Agy99           TLAWQRLRPWPDVVAGLTRLKTKFTLATLSNADVSAVVNISKRAALPWDA
MAV_2690|M.avium_104                TLAWQRLVPWPDVLPGLTRLKKKFIIATLSNADVSALINIAKRGGLPWDA
MAB_2863|M.abscessus_ATCC_1997      ASSWQRLVPWPDVPAGLAALRMRAVVATLSNTDMATMVNLFKRLDISWDA
Mflv_0739|M.gilvum_PYR-GCK          NRAWHRLDPWPDSVAGLTRLKQRFLITTLSNGNVSLLTDMAKRAGLPWDC
Mvan_0108|M.vanbaalenii_PYR-1       NRAWHRLDPWPDAVAGLTRLKRRFVITTLSNGNVSLLTNMAKRAGLPWDC
MSMEG_3450|M.smegmatis_MC2_155      VHAWHRLDPWPDVRDGLELLRSNFLIAPLSNGHVRLVVDLARHGDLRFDC
                                      :*:** ****   **  *: .  ::.*** .:  : :: ::  : :*.

MMAR_3371|M.marinum_M               IFAAEMAGVFKPDPAAYRMAVGYLGCEPAEVMMVASHKYDLRAAARLGLR
MUL_1268|M.ulcerans_Agy99           IFAAEMAGVFKPDPAAYRMAVGYLGCEPAEVMMVASHKYDLRAAARLGLR
MAV_2690|M.avium_104                VFAAEMAGVFKPDPAIYHMAARYLGLAPRQIMMVASHKYDIRAAASLGFQ
MAB_2863|M.abscessus_ATCC_1997      IFTAEVFGRFKPDPSVYRGALRYLGVEPYEAAMVAAHPYDLRAARQLGMG
Mflv_0739|M.gilvum_PYR-GCK          VLSAEIFGHYKPDREAYLGTAHILDVAPGELMMVAAHPSDLRAARDAGLV
Mvan_0108|M.vanbaalenii_PYR-1       VLSAEIFGHYKPDREAYLGCAEILDVAPGELMLVAAHPSDLRGARRAGLA
MSMEG_3450|M.smegmatis_MC2_155      ILSAELAHAYKPAPETYLTAAHLLDVDPSEVMLVAAHPSDLAGARAAGLR
                                    :::**:   :**    *      *.  * :  :**:*  *: .*   *: 

MMAR_3371|M.marinum_M               TAFVARPLEFG--IGGAADATYADEFDINAADFLD---LAGQLGC-----
MUL_1268|M.ulcerans_Agy99           TAFVARPLEFGSVVRPMQPMPMSSTSTPQTSSILPGNSVADRCGVETSFT
MAV_2690|M.avium_104                TAFVTRPFEFG--PLGLADTAYDDAFDVNAADLLD---LATQLSC-----
MAB_2863|M.abscessus_ATCC_1997      TIFVSRPHEYG--DPVLAHTDPDEEFDQRVTAIGE---LS----------
Mflv_0739|M.gilvum_PYR-GCK          TAYVHRPLEQG--PDRTPERPGHDEFDITASDFGD---FADQLGA-----
Mvan_0108|M.vanbaalenii_PYR-1       TAFVHRPLEQG--PDRAPARPADGEFDVMADDFHD---LADRLGV-----
MSMEG_3450|M.smegmatis_MC2_155      TAFIDRPLEHG--P-ATPKR-SDRKADVSAADLHE---LARLLGDEGKA-
                                    * :: ** * *                  .  :     .:          

MMAR_3371|M.marinum_M               -----
MUL_1268|M.ulcerans_Agy99           RTEFG
MAV_2690|M.avium_104                -----
MAB_2863|M.abscessus_ATCC_1997      -----
Mflv_0739|M.gilvum_PYR-GCK          -----
Mvan_0108|M.vanbaalenii_PYR-1       -----
MSMEG_3450|M.smegmatis_MC2_155      -----