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TTIHAKTHATVPALTPEQRDRILAAVDAQFDRQLKFTQELVRHPSLRGDEASAQDLLYGAMSGRGLEMDR WELDPEQLATHPGAGKVEISYRGVDNVVGTYRPRQELGRSLILNGHIDVVPEGPEAQWQRSPWEAEVVDG WLYGRGSGDMKAGLVANLFAFDALRAARLEPLGRIHFESVVEEECTGNGSLSALMRGYTADAVLIPEPEE DMLVRANVGTIWFRVRVAGHPTHPREMSSGFNAIDAAYFVVERLRRLEERWNAEKGKHRHFEDLEHPINL NVGKIKGGDWNSSVPAWCELDLRIAFYPGITADEAWSEITAELAAIEHDGNGHPVSAEATATGFYAEGYV LEEGSDAEAILGESHADAFGGAPLQSFTTPGYLDGRVFVQYANIPALVYGPISKDIHGFDERVDIESVRR ITKSIALFVARWCGVEDTAARH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3397 | - | - | 100% (443) | acetylornithine deacetylase |
| M. smegmatis MC2 155 | MSMEG_2491 | - | 8e-25 | 27.32% (399) | acetylornithine deacetylase |
| M. smegmatis MC2 155 | MSMEG_4755 | - | 2e-12 | 35.77% (137) | hypothetical protein MSMEG_4755 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2551c | - | 1e-09 | 34.40% (125) | hypothetical protein Mb2551c |
| M. gilvum PYR-GCK | Mflv_2534 | - | 1e-11 | 33.91% (174) | hypothetical protein Mflv_2534 |
| M. tuberculosis H37Rv | Rv2522c | - | 1e-09 | 34.40% (125) | hypothetical protein Rv2522c |
| M. leprae Br4923 | MLBr_01193 | - | 4e-10 | 35.20% (125) | hypothetical protein MLBr_01193 |
| M. abscessus ATCC 19977 | MAB_1336 | - | 3e-06 | 22.92% (336) | succinyl-diaminopimelate desuccinylase |
| M. marinum M | MMAR_3957 | argE | 5e-11 | 32.75% (171) | acetylornithine deacetylase ArgE |
| M. avium 104 | MAV_1652 | - | 1e-11 | 33.92% (171) | hypothetical protein MAV_1652 |
| M. thermoresistible (build 8) | TH_2370 | dapE2 | 3e-08 | 28.87% (194) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3812 | argE | 4e-11 | 32.75% (171) | hypothetical protein MUL_3812 |
| M. vanbaalenii PYR-1 | Mvan_4122 | - | 7e-13 | 33.91% (174) | hypothetical protein Mvan_4122 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3957|M.marinum_M --------------------MTDLVERVREVLPSVRQDLEKLVRIESVWA
MUL_3812|M.ulcerans_Agy99 --------------------MTDLVERVREVLPSVRQDLEKLVRIESVWA
Mb2551c|M.bovis_AF2122/97 MSASRRRIASKSGFSCDSASARELVERVREVLPSVRCDLEELVRIESVWA
Rv2522c|M.tuberculosis_H37Rv MSASRRRIASKSGFSCDSASARELVERVREVLPSVRCDLEELVRIESVWA
MLBr_01193|M.leprae_Br4923 --------------------MSDLIERVREVLPLVRRDLENLVRIESVWA
MAV_1652|M.avium_104 ---------------------------MREVLPSVRRDLEELVRIESVWA
Mflv_2534|M.gilvum_PYR-GCK --------------------MTDLVQRVRDVLPSVRADLEDLVRIQSVWA
Mvan_4122|M.vanbaalenii_PYR-1 ------------MSSFNLDGMSDLVQRVRDVLPSVRADLEDLVRIQSVWA
MSMEG_3397|M.smegmatis_MC2_155 -MTTIHAKTHATVPALTPEQRDRILAAVDAQFDRQLKFTQELVRHPSLRG
MAB_1336|M.abscessus_ATCC_1997 --------------------MALELAGDPIALTAALVDIPSESRHEAQIA
TH_2370|M.thermoresistible__bu -----------VTNPPQPADEVVDLVSTLIRFDTSNTGDPATTRVEAEAA
: * : .
MMAR_3957|M.marinum_M D------------PGRRAEVHRSAQAVADLLAQAGFDDVQIVSEGGAPAV
MUL_3812|M.ulcerans_Agy99 D------------PGRRAEVHRSAQTVADLLAQAGFDDVQIVSEGGAPAV
Mb2551c|M.bovis_AF2122/97 D------------PDRRDEVHRSARAVADLLSQAGFDDVRIVSERGAPAV
Rv2522c|M.tuberculosis_H37Rv D------------PDRRDEVHRSARAVADLLSQAGFDDVRIVSERGAPAV
MLBr_01193|M.leprae_Br4923 D------------PGRRNEVHRSAQVVLDLLSQAGFNFVRIVSEGGAPAV
MAV_1652|M.avium_104 D------------PGRRSEVQRSARAVADLLAQAGFGDVRIVSEGGAPAV
Mflv_2534|M.gilvum_PYR-GCK D------------PDRRAEVQRCAEAVSTLLSDAGFGDVRIVAEGGAPAV
Mvan_4122|M.vanbaalenii_PYR-1 D------------PARRAEVHRSAEAVSKLLSEAGFGDVRIVAEGGAPAV
MSMEG_3397|M.smegmatis_MC2_155 DEASAQDLLYGAMSGRGLEMDRWELDPEQLATHPGAGKVEISYRGVDNVV
MAB_1336|M.abscessus_ATCC_1997 D-------------------------AVEVALREQTSGFEVIRNGNAVLA
TH_2370|M.thermoresistible__bu H----------------------WVADRLREVGYQTEYVEAGAPGRGNVF
. ..
MMAR_3957|M.marinum_M IAQHPAPPGAPTVLLYAHHDVQPEGDPDQWASAPFEPTERDGRLYGRGTA
MUL_3812|M.ulcerans_Agy99 IAQHPAPPGAPTALLYAHHDVQPEGDPDQWASAPFEPTERDGRLYGRGTA
Mb2551c|M.bovis_AF2122/97 IARYPAPPGAPTVLLYAHHDVQPEGDRGQWVSPPFEPTERGGRLYGRGTA
Rv2522c|M.tuberculosis_H37Rv IARYPAPPGAPTVLLYAHHDVQPEGDRGQWVSPPFEPTERGGRLYGRGTA
MLBr_01193|M.leprae_Br4923 IARYPAPLGTPTVLLYAHHDVQPEGDRDQWASPPFEPTERDGRIYGRGSA
MAV_1652|M.avium_104 IARHPAPPGAPTVLLYAHHDVQPEGDRGQWVSPPFEPTERDGRLYGRGSA
Mflv_2534|M.gilvum_PYR-GCK IARHPAPEGAPTVLLYAHHDVQPEGDPAQWHTPPFEPTERGGRLYGRGTA
Mvan_4122|M.vanbaalenii_PYR-1 IAHHPAPEGAPTVLLYAHHDVQPEGDPGQWHTAPFEPTERDGRLYGRGTA
MSMEG_3397|M.smegmatis_MC2_155 GTYRPRQELGRSLILNGHIDVVPEGPEAQWQRSPWEAEVVDGWLYGRGSG
MAB_1336|M.abscessus_ATCC_1997 RTNNG---LGTRVMLAGHLDTVPAADN-------VPSRHEGEILHGCGTV
TH_2370|M.thermoresistible__bu ARLPGADPSRGALLVHGHLDVVP-AEPADWSVHPFSGAVEDGYVWGRGAV
:: .* *. * . . : * *:
MMAR_3957|M.marinum_M DDKAGIATHLAAFRAHDGK--PPVGVTVFVEG--EEESGSPSLGRLLAAH
MUL_3812|M.ulcerans_Agy99 DDKAGIATHLAAFRAHDGK--PPVGVTVFVEG--EEESGSPSLGRLLAAH
Mb2551c|M.bovis_AF2122/97 DDKAGIATHVAAFWAHGGR--PPVGVTVFVEG--EEESGSPSLGRLLAAH
Rv2522c|M.tuberculosis_H37Rv DDKAGIATHVAAFWAHGGR--PPVGVTVFVEG--EEESGSPSLGRLLAAH
MLBr_01193|M.leprae_Br4923 DDKAGIATHLAAFRAHGGR--PPVGVTVFVEG--EEESGSPSLGRLLAAH
MAV_1652|M.avium_104 DDKAGIATHLAAFRAHGGR--PPVGVTVFVEG--EEESGSPSLGRLLAAQ
Mflv_2534|M.gilvum_PYR-GCK DDKAGIATHLAAFRAHGGN--PPVGVTVFVEG--EEESGSPSLSRLLAEH
Mvan_4122|M.vanbaalenii_PYR-1 DDKAGIATHLAAFRAHGGN--PPVGVTVFVEG--EEESGSPSLSRLLATH
MSMEG_3397|M.smegmatis_MC2_155 DMKAGLVANLFAFDALRAARLEPLGR-IHFES--VVEEECTGNGSLSALM
MAB_1336|M.abscessus_ATCC_1997 DMKSGDAVFLHLAATVTPR--VDLTLVFYDCE--EIESSANGLGRIEREL
TH_2370|M.thermoresistible__bu DMKNMLGMMLAVARHFKRAGIVPPRDIVFAFLSDEEHGGTYGAQWLVDHR
* * : .. . . :
MMAR_3957|M.marinum_M RDVLAADVIVIADSDNWSTDVPALTVSLRGMADCVVEVATLDHG--LHSG
MUL_3812|M.ulcerans_Agy99 RDVLAADVIVIADSDNWSTDVPALTVSLRGMADCVVEVATLDHG--LHSG
Mb2551c|M.bovis_AF2122/97 RDALAADVIVIADSDNWSTDIPALTVSLRGMADCVVEVATLDHG--LHSG
Rv2522c|M.tuberculosis_H37Rv RDALAADVIVIADSDNWSTDIPALTVSLRGMADCVVEVATLDHG--LHSG
MLBr_01193|M.leprae_Br4923 RDALAADVIIIADSDNWSTDVPALTVSLRGLVDCVVEVATLDHG--LHSG
MAV_1652|M.avium_104 RDTLAADVIVIADSDNWSVDTPALTVSLRGLVDCVVEVATLDHG--LHSG
Mflv_2534|M.gilvum_PYR-GCK RDLLAADVIVIADSDNWSTEIPSLTVSLRGLADCVVEVATLDHG--LHSG
Mvan_4122|M.vanbaalenii_PYR-1 REALAADVIVIADSDNWSTDIPSLTVSLRGLADCVVEVATLDHG--LHSG
MSMEG_3397|M.smegmatis_MC2_155 RGYTADAVLIPEPEEDMLVRANVGTIWFR---VRVAGHPTHPRE--MSSG
MAB_1336|M.abscessus_ATCC_1997 PDWLDADLAILGEP-----TAGLIEAGCQGTLRVVIRTRGTRAH--SARS
TH_2370|M.thermoresistible__bu PDLFTGVTEAIGEVGGFSLTVPRKDGGERRLYLVETAEKGLAWMRLTARG
: .
MMAR_3957|M.marinum_M LWGGVVPDALSVLVRLLASLHDDDGNVAVAGLHES---TAAAVDYPPERV
MUL_3812|M.ulcerans_Agy99 LWGGVVPDALSVLVRLLASLHDDDGNVAVAGLHES---TAAAVDYPPERV
Mb2551c|M.bovis_AF2122/97 LWGGVVPDALTVLVRLLASLHDDDGNVAVAGMHES---TAARVDYPAGRV
Rv2522c|M.tuberculosis_H37Rv LWGGVVPDALTVLVRLLASLHDDDGNVAVAGMHES---TAARVDYPAGRV
MLBr_01193|M.leprae_Br4923 LWGGVVPDALSVLMRLLASLHDDDGNVAVAGLHEST--TAADVNYPHERV
MAV_1652|M.avium_104 LWGGVVPDALSVLVRLLASLHDDDGNVAVAGLHETDIATLNYPDYPPERV
Mflv_2534|M.gilvum_PYR-GCK MWGGVVPDALTVLVRLLAGLHDDDGNVAVEGLHETDTADRDFPDYTPERV
Mvan_4122|M.vanbaalenii_PYR-1 MWGGVVPDALSVLVRLLASLHDDDGNVAVEGLHEPVTAAADFPDYTPDRV
MSMEG_3397|M.smegmatis_MC2_155 FN---AIDAAYFVVERLRRLEERWN--AEKGKHRH----FEDLEHPIN--
MAB_1336|M.abscessus_ATCC_1997 WLGDNAIHKLAAVLDRLAAYRARIVDIDGCQYREG---------------
TH_2370|M.thermoresistible__bu RAGHGSMVNDDNAVTAVAEAVARLGRHRFPLVLTESVQQFLEAVAEETGY
: :
MMAR_3957|M.marinum_M RADSGLLDGVTEIGSGSVPQRLWAKPAITVIGIDTTSIAAASNTLIPRAR
MUL_3812|M.ulcerans_Agy99 RADSGLLDGVTEIGSGSVPQRLWAKPAITVIGIDTTSIAAASNTLIPRAR
Mb2551c|M.bovis_AF2122/97 RAESGLLDGVSEIGTGSVPQRLWAKPAITVIGIDTTSVAAASNTLIPRAR
Rv2522c|M.tuberculosis_H37Rv RAESGLLDGVSEIGTGSVPQRLWAKPAITVIGIDTTSVAAASNTLIPRAR
MLBr_01193|M.leprae_Br4923 RADSGLLDGVSEIGSGSVPQRLWAKPAITVIGIDTTSVAAASNMLIPRAR
MAV_1652|M.avium_104 RADSGVLPGVSEIGSGSVPQRLWAKPAITVIGIDATPVERASNTLIPRAR
Mflv_2534|M.gilvum_PYR-GCK RSDTGVLDGVTEIGSGSVAQRLWAKPAITVVGIDTTPIAKASNTLIPRAR
Mvan_4122|M.vanbaalenii_PYR-1 RADTGLLDGVREIGSGSVAQRLWAKPAITVIGIDTTPIAQASNTLIARAR
MSMEG_3397|M.smegmatis_MC2_155 ------------LNVGKIKGGDWNSSVPAWCELDLR-IAFYPGITADEAW
MAB_1336|M.abscessus_ATCC_1997 ------------LSAVRIDGG------------------VAGNVIPDEAA
TH_2370|M.thermoresistible__bu SFDVNSPDLEGTIAKLGGVARIVGATLRDTANPTMLTAGYKANVIPQTAE
: . *
MMAR_3957|M.marinum_M AKISIRIAPGGDAAAHLDAVEAHLRKHAPWGARVSVERGDIGQPYAIDAS
MUL_3812|M.ulcerans_Agy99 AKISIRIAPGGDAAAHLDAVEAHLRKHAPWGARVSVERGDIGQPYAIDAS
Mb2551c|M.bovis_AF2122/97 AKISIRVAPGGDATAHLDAVEAHLRRHAPWGAQVTVTRGEVGQPYAIEAS
Rv2522c|M.tuberculosis_H37Rv AKISIRVAPGGDATAHLDAVEAHLRRHAPWGAQVTVTRGEVGQPYAIEAS
MLBr_01193|M.leprae_Br4923 AKISMRIAPGGDAAVHLDALTAHLQRYAPWGAQVSVIRGEVSQPYAIEAS
MAV_1652|M.avium_104 AKISMRVAPGGDAAAHLDALTAHLQQHAPWGAQVSVTRGDIGEPYAIDAS
Mflv_2534|M.gilvum_PYR-GCK AKVSMRVAPGGDAAAHLAALTRHLESRAPWGAQVTVTPGDVGEPYAIDAA
Mvan_4122|M.vanbaalenii_PYR-1 AKVSMRVAPGGDAAAHLAALTRHLEGHAPWGAKVTVTPGDVGEPYAIAAS
MSMEG_3397|M.smegmatis_MC2_155 SEITAELAA-----------IEHDGNGHPVSAEATAT-GFYAEGYVLEEG
MAB_1336|M.abscessus_ATCC_1997 VTVNFRFAP------------DRSPEQALVHVHEVFDGLDVQIELTDSAA
TH_2370|M.thermoresistible__bu AIVDCRVLPG-------RRAAFEREVDELIGPDVERSWERDLPAVETTFD
: .. . .
MMAR_3957|M.marinum_M GPVYDAARTAFRQAWGADPIDMGMGGSIPFIAEFAEAFPDAKILV----T
MUL_3812|M.ulcerans_Agy99 GPVYDAARTAFRQAWGADPIDMGMGGSIPFIAEFAEAFPDAKILV----T
Mb2551c|M.bovis_AF2122/97 GPVYDAARSAFRQAWGADPIDMGMGGSIPFIAEFAAAFPQATILV----T
Rv2522c|M.tuberculosis_H37Rv GPVYDAARSAFRQAWGADPIDMGMGGSIPFIAEFAAAFPQATILV----T
MLBr_01193|M.leprae_Br4923 GGVYDTARTAFRQAWGADPTDMGMGGSIPFIAEFASAFPQAKILV----T
MAV_1652|M.avium_104 GSVYDAARAAFRQAWGTEPIDMGMGGSIPFIAEFAAAFPEAKILV----T
Mflv_2534|M.gilvum_PYR-GCK GPVYDAVRDVFRQAWGRDGVDTGVGGSIPFIAEFAAAFPEAKILV----T
Mvan_4122|M.vanbaalenii_PYR-1 GPVYDAARSAFREAWGHDAVDTGVGGSIPFIAEFAAAFPDAKILV----T
MSMEG_3397|M.smegmatis_MC2_155 SDAEAILGESHADAFGGAPLQS-FTTPGYLDGRVFVQYANIPALV----Y
MAB_1336|M.abscessus_ATCC_1997 GALPGLDRPAAAELVGAAGGVVRAKYGWTDVSRFAARGIAAVNYG----P
TH_2370|M.thermoresistible__bu GELVDAMNASLLAVDPEARTVPYMMSGGTDAKAFQRLGIRCFGFVPLRLP
. .
MMAR_3957|M.marinum_M GVEDPGTQAHSVNESLHLGVLERAAVAEALLLANLA---------
MUL_3812|M.ulcerans_Agy99 GVEDPGTQAHSVNESLHLGVLERAAVAEALLLANLA---------
Mb2551c|M.bovis_AF2122/97 GVEDPGTQAHSVNESLHLGVLERAATAEALLLAKLAAIPTGRAEA
Rv2522c|M.tuberculosis_H37Rv GVEDPGTQAHSVNESLHLGVLERAATAEALLLAKLAAIPTGRAEA
MLBr_01193|M.leprae_Br4923 GVGDPATQAHGVNESVHLGVLERAAVAEALLLANLA---------
MAV_1652|M.avium_104 GVEDPATQAHSINESLHLGVLERAAISEALLLANLADLADLPNPG
Mflv_2534|M.gilvum_PYR-GCK GVEDPDTQAHSINESLHLGVLERAATAEALLLGRLGDLDGQVAS-
Mvan_4122|M.vanbaalenii_PYR-1 GVEDPDTQAHSINESLHLGVLERAATAEALLLARLGGSDGQPAS-
MSMEG_3397|M.smegmatis_MC2_155 GP--ISKDIHGFDERVDIESVRRITKSIALFVARWCGVEDTAARH
MAB_1336|M.abscessus_ATCC_1997 GD---PNLAHTRGEHVPVQQITAVTEVLRRYLTV-----------
TH_2370|M.thermoresistible__bu PELDFSALFHGVDERVPVDALEFGARVLDHFLQHC----------
* .* : : : : :