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MTDLVQRVRDVLPSVRADLEDLVRIQSVWADPDRRAEVQRCAEAVSTLLSDAGFGDVRIVAEGGAPAVIA RHPAPEGAPTVLLYAHHDVQPEGDPAQWHTPPFEPTERGGRLYGRGTADDKAGIATHLAAFRAHGGNPPV GVTVFVEGEEESGSPSLSRLLAEHRDLLAADVIVIADSDNWSTEIPSLTVSLRGLADCVVEVATLDHGLH SGMWGGVVPDALTVLVRLLAGLHDDDGNVAVEGLHETDTADRDFPDYTPERVRSDTGVLDGVTEIGSGSV AQRLWAKPAITVVGIDTTPIAKASNTLIPRARAKVSMRVAPGGDAAAHLAALTRHLESRAPWGAQVTVTP GDVGEPYAIDAAGPVYDAVRDVFRQAWGRDGVDTGVGGSIPFIAEFAAAFPEAKILVTGVEDPDTQAHSI NESLHLGVLERAATAEALLLGRLGDLDGQVAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2534 | - | - | 100% (452) | hypothetical protein Mflv_2534 |
| M. gilvum PYR-GCK | Mflv_3037 | - | 1e-07 | 28.66% (164) | hypothetical protein Mflv_3037 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2551c | - | 0.0 | 80.50% (441) | hypothetical protein Mb2551c |
| M. tuberculosis H37Rv | Rv2522c | - | 0.0 | 80.50% (441) | hypothetical protein Rv2522c |
| M. leprae Br4923 | MLBr_01193 | - | 0.0 | 77.48% (444) | hypothetical protein MLBr_01193 |
| M. abscessus ATCC 19977 | MAB_2102 | - | 4e-06 | 28.57% (154) | hypothetical protein MAB_2102 |
| M. marinum M | MMAR_3957 | argE | 0.0 | 81.04% (443) | acetylornithine deacetylase ArgE |
| M. avium 104 | MAV_1652 | - | 0.0 | 82.69% (439) | hypothetical protein MAV_1652 |
| M. smegmatis MC2 155 | MSMEG_4755 | - | 0.0 | 81.41% (441) | hypothetical protein MSMEG_4755 |
| M. thermoresistible (build 8) | TH_1101 | - | 1e-140 | 81.19% (303) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3812 | argE | 0.0 | 80.59% (443) | hypothetical protein MUL_3812 |
| M. vanbaalenii PYR-1 | Mvan_4122 | - | 0.0 | 90.49% (452) | hypothetical protein Mvan_4122 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2534|M.gilvum_PYR-GCK --------------------MTDLVQRVRDVLPSVRADLEDLVRIQSVWA
Mvan_4122|M.vanbaalenii_PYR-1 ------------MSSFNLDGMSDLVQRVRDVLPSVRADLEDLVRIQSVWA
MSMEG_4755|M.smegmatis_MC2_155 -----------------------MVARVKQVLPSVRADLEDLVRIQSVWA
TH_1101|M.thermoresistible__bu --------------------------------------------------
MMAR_3957|M.marinum_M --------------------MTDLVERVREVLPSVRQDLEKLVRIESVWA
MUL_3812|M.ulcerans_Agy99 --------------------MTDLVERVREVLPSVRQDLEKLVRIESVWA
Mb2551c|M.bovis_AF2122/97 MSASRRRIASKSGFSCDSASARELVERVREVLPSVRCDLEELVRIESVWA
Rv2522c|M.tuberculosis_H37Rv MSASRRRIASKSGFSCDSASARELVERVREVLPSVRCDLEELVRIESVWA
MLBr_01193|M.leprae_Br4923 --------------------MSDLIERVREVLPLVRRDLENLVRIESVWA
MAV_1652|M.avium_104 ---------------------------MREVLPSVRRDLEELVRIESVWA
MAB_2102|M.abscessus_ATCC_1997 -----------------------MTSVNPAPEDEVVDLVSTLIRFDTSNT
Mflv_2534|M.gilvum_PYR-GCK DPDRRAE-VQRCAEAVSTLLSDAGFGDVRIVA-EGGAPAVIARHP-APEG
Mvan_4122|M.vanbaalenii_PYR-1 DPARRAE-VHRSAEAVSKLLSEAGFGDVRIVA-EGGAPAVIAHHP-APEG
MSMEG_4755|M.smegmatis_MC2_155 DPARRGE-VTRSAEAVAKLLTDAGFGDVRIVS-EGGAPAVIAHHP-APSG
TH_1101|M.thermoresistible__bu --------------------------------------------------
MMAR_3957|M.marinum_M DPGRRAE-VHRSAQAVADLLAQAGFDDVQIVS-EGGAPAVIAQHP-APPG
MUL_3812|M.ulcerans_Agy99 DPGRRAE-VHRSAQTVADLLAQAGFDDVQIVS-EGGAPAVIAQHP-APPG
Mb2551c|M.bovis_AF2122/97 DPDRRDE-VHRSARAVADLLSQAGFDDVRIVS-ERGAPAVIARYP-APPG
Rv2522c|M.tuberculosis_H37Rv DPDRRDE-VHRSARAVADLLSQAGFDDVRIVS-ERGAPAVIARYP-APPG
MLBr_01193|M.leprae_Br4923 DPGRRNE-VHRSAQVVLDLLSQAGFNFVRIVS-EGGAPAVIARYP-APLG
MAV_1652|M.avium_104 DPGRRSE-VQRSARAVADLLAQAGFGDVRIVS-EGGAPAVIARHP-APPG
MAB_2102|M.abscessus_ATCC_1997 GELETTKGEAECARWIQQQLEEVGYTCEYVEAGAPGRGNLFARLPGASSD
Mflv_2534|M.gilvum_PYR-GCK APTVLLYAHHDVQPEGDPAQWHTPPFEPTERGGRLYGRGTADDK--AGIA
Mvan_4122|M.vanbaalenii_PYR-1 APTVLLYAHHDVQPEGDPGQWHTAPFEPTERDGRLYGRGTADDK--AGIA
MSMEG_4755|M.smegmatis_MC2_155 APTVLLYAHHDVQPEGDPAQWDSPPFEPTERDGRLYGRGTADDK--AGIA
TH_1101|M.thermoresistible__bu --------------------------------------------------
MMAR_3957|M.marinum_M APTVLLYAHHDVQPEGDPDQWASAPFEPTERDGRLYGRGTADDK--AGIA
MUL_3812|M.ulcerans_Agy99 APTALLYAHHDVQPEGDPDQWASAPFEPTERDGRLYGRGTADDK--AGIA
Mb2551c|M.bovis_AF2122/97 APTVLLYAHHDVQPEGDRGQWVSPPFEPTERGGRLYGRGTADDK--AGIA
Rv2522c|M.tuberculosis_H37Rv APTVLLYAHHDVQPEGDRGQWVSPPFEPTERGGRLYGRGTADDK--AGIA
MLBr_01193|M.leprae_Br4923 TPTVLLYAHHDVQPEGDRDQWASPPFEPTERDGRIYGRGSADDK--AGIA
MAV_1652|M.avium_104 APTVLLYAHHDVQPEGDRGQWVSPPFEPTERDGRLYGRGSADDK--AGIA
MAB_2102|M.abscessus_ATCC_1997 RGALLIHGHLDVVP-AEAPDWSVHPFSGAVNDGYVWGRGAVDMKDMVGMM
Mflv_2534|M.gilvum_PYR-GCK THLAAFRAHGGNPPVG--VTVFVEGEEESGSPSLSRLLAEHRDLLAADVI
Mvan_4122|M.vanbaalenii_PYR-1 THLAAFRAHGGNPPVG--VTVFVEGEEESGSPSLSRLLATHREALAADVI
MSMEG_4755|M.smegmatis_MC2_155 THLAAVRAFDGKPPVG--VTVFVEGEEESGSPSLGALLAAHRDALAADVI
TH_1101|M.thermoresistible__bu ------------------VTVFVEGEEESGSPSLGRLLAAHRDALAADVI
MMAR_3957|M.marinum_M THLAAFRAHDGKPPVG--VTVFVEGEEESGSPSLGRLLAAHRDVLAADVI
MUL_3812|M.ulcerans_Agy99 THLAAFRAHDGKPPVG--VTVFVEGEEESGSPSLGRLLAAHRDVLAADVI
Mb2551c|M.bovis_AF2122/97 THVAAFWAHGGRPPVG--VTVFVEGEEESGSPSLGRLLAAHRDALAADVI
Rv2522c|M.tuberculosis_H37Rv THVAAFWAHGGRPPVG--VTVFVEGEEESGSPSLGRLLAAHRDALAADVI
MLBr_01193|M.leprae_Br4923 THLAAFRAHGGRPPVG--VTVFVEGEEESGSPSLGRLLAAHRDALAADVI
MAV_1652|M.avium_104 THLAAFRAHGGRPPVG--VTVFVEGEEESGSPSLGRLLAAQRDTLAADVI
MAB_2102|M.abscessus_ATCC_1997 IAIARYFKRSGIVPPRDLVWAFVSDEENGGKWGSQWLVDNRPDLFEGITE
* .**..**:.*. . *: : : : . .
Mflv_2534|M.gilvum_PYR-GCK VIADSDNWSTEIPSLTVSLRGLADCVVEVATLDHGLHSGMWGGVVPDALT
Mvan_4122|M.vanbaalenii_PYR-1 VIADSDNWSTDIPSLTVSLRGLADCVVEVATLDHGLHSGMWGGVVPDALS
MSMEG_4755|M.smegmatis_MC2_155 IIADSDNWSTEQPALTVSLRGLADCVVEVATLDHGLHSGLWGGVVPDALS
TH_1101|M.thermoresistible__bu IIADSDNWSTEVPALTVSLRGLVDCVVEVATLDHGLHSGLWGGVVPDALS
MMAR_3957|M.marinum_M VIADSDNWSTDVPALTVSLRGMADCVVEVATLDHGLHSGLWGGVVPDALS
MUL_3812|M.ulcerans_Agy99 VIADSDNWSTDVPALTVSLRGMADCVVEVATLDHGLHSGLWGGVVPDALS
Mb2551c|M.bovis_AF2122/97 VIADSDNWSTDIPALTVSLRGMADCVVEVATLDHGLHSGLWGGVVPDALT
Rv2522c|M.tuberculosis_H37Rv VIADSDNWSTDIPALTVSLRGMADCVVEVATLDHGLHSGLWGGVVPDALT
MLBr_01193|M.leprae_Br4923 IIADSDNWSTDVPALTVSLRGLVDCVVEVATLDHGLHSGLWGGVVPDALS
MAV_1652|M.avium_104 VIADSDNWSVDTPALTVSLRGLVDCVVEVATLDHGLHSGLWGGVVPDALS
MAB_2102|M.abscessus_ATCC_1997 AIGEVGGFSLTVPRRQGGER----RLYLLETAEKGIAWMRLTAKARAGHG
*.: ..:* * . * : : * ::*: . . .
Mflv_2534|M.gilvum_PYR-GCK VLVRLLAGLHDDDGNVAVEGLHETDTADRDFPDYTPERVRSDTGVLDGVT
Mvan_4122|M.vanbaalenii_PYR-1 VLVRLLASLHDDDGNVAVEGLHEPVTAAADFPDYTPDRVRADTGLLDGVR
MSMEG_4755|M.smegmatis_MC2_155 VLVRLLASLHDDEGNVAVEGLHEATAADVDR---GADWVRQESGLLDGVS
TH_1101|M.thermoresistible__bu VLVRLLASLHDDDGNVAVAGLHEATVADVDR---GPDWVRAEAGLLDGVR
MMAR_3957|M.marinum_M VLVRLLASLHDDDGNVAVAGLHES---TAAAVDYPPERVRADSGLLDGVT
MUL_3812|M.ulcerans_Agy99 VLVRLLASLHDDDGNVAVAGLHES---TAAAVDYPPERVRADSGLLDGVT
Mb2551c|M.bovis_AF2122/97 VLVRLLASLHDDDGNVAVAGMHES---TAARVDYPAGRVRAESGLLDGVS
Rv2522c|M.tuberculosis_H37Rv VLVRLLASLHDDDGNVAVAGMHES---TAARVDYPAGRVRAESGLLDGVS
MLBr_01193|M.leprae_Br4923 VLMRLLASLHDDDGNVAVAGLHEST--TAADVNYPHERVRADSGLLDGVS
MAV_1652|M.avium_104 VLVRLLASLHDDDGNVAVAGLHETDIATLNYPDYPPERVRADSGVLPGVS
MAB_2102|M.abscessus_ATCC_1997 SMVHEDNAVTAVAEAVAKLGRHRFPLVLTEAVTQFLGAVAEETGYDFDPD
::: .: ** * *. * ::* .
Mflv_2534|M.gilvum_PYR-GCK EIGSGSVAQRLWAKPAITVVGIDTTP------IAKASNTLIPRARAKVSM
Mvan_4122|M.vanbaalenii_PYR-1 EIGSGSVAQRLWAKPAITVIGIDTTP------IAQASNTLIARARAKVSM
MSMEG_4755|M.smegmatis_MC2_155 EIGSGSVVQRMWAKPAVTVIGIDTTP------IGKSSNTLIPRARAKISM
TH_1101|M.thermoresistible__bu QIGTGTVAQRLWAKPAITVIGIDTTP------IAAASNTLIPRARAKISM
MMAR_3957|M.marinum_M EIGSGSVPQRLWAKPAITVIGIDTTS------IAAASNTLIPRARAKISI
MUL_3812|M.ulcerans_Agy99 EIGSGSVPQRLWAKPAITVIGIDTTS------IAAASNTLIPRARAKISI
Mb2551c|M.bovis_AF2122/97 EIGTGSVPQRLWAKPAITVIGIDTTS------VAAASNTLIPRARAKISI
Rv2522c|M.tuberculosis_H37Rv EIGTGSVPQRLWAKPAITVIGIDTTS------VAAASNTLIPRARAKISI
MLBr_01193|M.leprae_Br4923 EIGSGSVPQRLWAKPAITVIGIDTTS------VAAASNMLIPRARAKISM
MAV_1652|M.avium_104 EIGSGSVPQRLWAKPAITVIGIDATP------VERASNTLIPRARAKISM
MAB_2102|M.abscessus_ATCC_1997 SPDLEGTVAKLGSIGKIVGATLRDTANPTMLKAGYKANVIPATAEAVIDC
. . . :: : :. : *. :* : . *.* :.
Mflv_2534|M.gilvum_PYR-GCK RVAPGGDAAAHLAALTRHLESRAPWGAQVTVTPGDVGEPYAIDAAGPVYD
Mvan_4122|M.vanbaalenii_PYR-1 RVAPGGDAAAHLAALTRHLEGHAPWGAKVTVTPGDVGEPYAIAASGPVYD
MSMEG_4755|M.smegmatis_MC2_155 RVAPGGDARAHLEALTRHLEANTPWGAKVTVTPGDIGQPYAIDASGPVYD
TH_1101|M.thermoresistible__bu RVAPGGDARAHLDALTRHLHEHTPWGAHVTVTPGEIGEPYAIDADGPVYD
MMAR_3957|M.marinum_M RIAPGGDAAAHLDAVEAHLRKHAPWGARVSVERGDIGQPYAIDASGPVYD
MUL_3812|M.ulcerans_Agy99 RIAPGGDAAAHLDAVEAHLRKHAPWGARVSVERGDIGQPYAIDASGPVYD
Mb2551c|M.bovis_AF2122/97 RVAPGGDATAHLDAVEAHLRRHAPWGAQVTVTRGEVGQPYAIEASGPVYD
Rv2522c|M.tuberculosis_H37Rv RVAPGGDATAHLDAVEAHLRRHAPWGAQVTVTRGEVGQPYAIEASGPVYD
MLBr_01193|M.leprae_Br4923 RIAPGGDAAVHLDALTAHLQRYAPWGAQVSVIRGEVSQPYAIEASGGVYD
MAV_1652|M.avium_104 RVAPGGDAAAHLDALTAHLQQHAPWGAQVSVTRGDIGEPYAIDASGSVYD
MAB_2102|M.abscessus_ATCC_1997 RVLPG-----RLEAFEREVDEII--GPDVEREWVQLLPAYETTFDGDLVD
*: ** :* *. .: *. * :: .* * : *
Mflv_2534|M.gilvum_PYR-GCK AVRDVFRQAWGRD-GVDTGVGG---SIPFIAEFAAAFPEAKILVTGVEDP
Mvan_4122|M.vanbaalenii_PYR-1 AARSAFREAWGHD-AVDTGVGG---SIPFIAEFAAAFPDAKILVTGVEDP
MSMEG_4755|M.smegmatis_MC2_155 AARAAFGKAWGHE-PVDMGMGG---SIPFIAEFAAAFPDATILVTGVEDP
TH_1101|M.thermoresistible__bu AARAAFREAWGRE-PVDMGMGG---SIPFIAEFAAAFPDATILVTGVEDP
MMAR_3957|M.marinum_M AARTAFRQAWGAD-PIDMGMGG---SIPFIAEFAEAFPDAKILVTGVEDP
MUL_3812|M.ulcerans_Agy99 AARTAFRQAWGAD-PIDMGMGG---SIPFIAEFAEAFPDAKILVTGVEDP
Mb2551c|M.bovis_AF2122/97 AARSAFRQAWGAD-PIDMGMGG---SIPFIAEFAAAFPQATILVTGVEDP
Rv2522c|M.tuberculosis_H37Rv AARSAFRQAWGAD-PIDMGMGG---SIPFIAEFAAAFPQATILVTGVEDP
MLBr_01193|M.leprae_Br4923 TARTAFRQAWGAD-PTDMGMGG---SIPFIAEFASAFPQAKILVTGVGDP
MAV_1652|M.avium_104 AARAAFRQAWGTE-PIDMGMGG---SIPFIAEFAAAFPEAKILVTGVEDP
MAB_2102|M.abscessus_ATCC_1997 AMNAAVLEFDPEARTVPYMLSGGTDAKAFARLGIRCFGFAPLKLPPELDF
: . .. : :.* : .* .* * : :. *
Mflv_2534|M.gilvum_PYR-GCK DTQAHSINESLHLGVLERAATAEALLLGRLGDLDGQVAS-
Mvan_4122|M.vanbaalenii_PYR-1 DTQAHSINESLHLGVLERAATAEALLLARLGGSDGQPAS-
MSMEG_4755|M.smegmatis_MC2_155 GTQAHSINESLHLGVFEKAATAEALLLDALGR--------
TH_1101|M.thermoresistible__bu GTQAHSVNESLHLGVLQRAATAEALLLARLGG--------
MMAR_3957|M.marinum_M GTQAHSVNESLHLGVLERAAVAEALLLANLA---------
MUL_3812|M.ulcerans_Agy99 GTQAHSVNESLHLGVLERAAVAEALLLANLA---------
Mb2551c|M.bovis_AF2122/97 GTQAHSVNESLHLGVLERAATAEALLLAKLAAIPTGRAEA
Rv2522c|M.tuberculosis_H37Rv GTQAHSVNESLHLGVLERAATAEALLLAKLAAIPTGRAEA
MLBr_01193|M.leprae_Br4923 ATQAHGVNESVHLGVLERAAVAEALLLANLA---------
MAV_1652|M.avium_104 ATQAHSINESLHLGVLERAAISEALLLANLADLADLPNPG
MAB_2102|M.abscessus_ATCC_1997 ASLFHGVDERVPVDALTFGTKVLQHFLLNH----------
: *.::* : :..: .: :*