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SSFNLDGMSDLVQRVRDVLPSVRADLEDLVRIQSVWADPARRAEVHRSAEAVSKLLSEAGFGDVRIVAEG GAPAVIAHHPAPEGAPTVLLYAHHDVQPEGDPGQWHTAPFEPTERDGRLYGRGTADDKAGIATHLAAFRA HGGNPPVGVTVFVEGEEESGSPSLSRLLATHREALAADVIVIADSDNWSTDIPSLTVSLRGLADCVVEVA TLDHGLHSGMWGGVVPDALSVLVRLLASLHDDDGNVAVEGLHEPVTAAADFPDYTPDRVRADTGLLDGVR EIGSGSVAQRLWAKPAITVIGIDTTPIAQASNTLIARARAKVSMRVAPGGDAAAHLAALTRHLEGHAPWG AKVTVTPGDVGEPYAIAASGPVYDAARSAFREAWGHDAVDTGVGGSIPFIAEFAAAFPDAKILVTGVEDP DTQAHSINESLHLGVLERAATAEALLLARLGGSDGQPAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4122 | - | - | 100% (460) | hypothetical protein Mvan_4122 |
| M. vanbaalenii PYR-1 | Mvan_3489 | - | 4e-06 | 27.44% (164) | hypothetical protein Mvan_3489 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2551c | - | 0.0 | 80.75% (452) | hypothetical protein Mb2551c |
| M. gilvum PYR-GCK | Mflv_2534 | - | 0.0 | 90.49% (452) | hypothetical protein Mflv_2534 |
| M. tuberculosis H37Rv | Rv2522c | - | 0.0 | 80.75% (452) | hypothetical protein Rv2522c |
| M. leprae Br4923 | MLBr_01193 | - | 0.0 | 79.46% (443) | hypothetical protein MLBr_01193 |
| M. abscessus ATCC 19977 | MAB_2311 | - | 2e-06 | 25.66% (343) | hypothetical protein MAB_2311 |
| M. marinum M | MMAR_3957 | argE | 0.0 | 83.30% (443) | acetylornithine deacetylase ArgE |
| M. avium 104 | MAV_1652 | - | 0.0 | 82.80% (436) | hypothetical protein MAV_1652 |
| M. smegmatis MC2 155 | MSMEG_4755 | - | 0.0 | 83.67% (441) | hypothetical protein MSMEG_4755 |
| M. thermoresistible (build 8) | TH_1101 | - | 1e-144 | 83.88% (304) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3812 | argE | 0.0 | 82.84% (443) | hypothetical protein MUL_3812 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4122|M.vanbaalenii_PYR-1 --------------MSSFNLDGMSDLVQRVRDVLPSVRAD---LEDLVRI
Mflv_2534|M.gilvum_PYR-GCK ----------------------MTDLVQRVRDVLPSVRAD---LEDLVRI
MSMEG_4755|M.smegmatis_MC2_155 -------------------------MVARVKQVLPSVRAD---LEDLVRI
TH_1101|M.thermoresistible__bu --------------------------------------------------
MMAR_3957|M.marinum_M ----------------------MTDLVERVREVLPSVRQD---LEKLVRI
MUL_3812|M.ulcerans_Agy99 ----------------------MTDLVERVREVLPSVRQD---LEKLVRI
Mb2551c|M.bovis_AF2122/97 --MSASRRRIASKSGFSCDSASARELVERVREVLPSVRCD---LEELVRI
Rv2522c|M.tuberculosis_H37Rv --MSASRRRIASKSGFSCDSASARELVERVREVLPSVRCD---LEELVRI
MLBr_01193|M.leprae_Br4923 ----------------------MSDLIERVREVLPLVRRD---LENLVRI
MAV_1652|M.avium_104 -----------------------------MREVLPSVRRD---LEELVRI
MAB_2311|M.abscessus_ATCC_1997 MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYRE
Mvan_4122|M.vanbaalenii_PYR-1 QSVWADPARRAEVHRSAEAVSKLLSEAGFGDVRIVAEG-----GAPAVIA
Mflv_2534|M.gilvum_PYR-GCK QSVWADPDRRAEVQRCAEAVSTLLSDAGFGDVRIVAEG-----GAPAVIA
MSMEG_4755|M.smegmatis_MC2_155 QSVWADPARRGEVTRSAEAVAKLLTDAGFGDVRIVSEG-----GAPAVIA
TH_1101|M.thermoresistible__bu --------------------------------------------------
MMAR_3957|M.marinum_M ESVWADPGRRAEVHRSAQAVADLLAQAGFDDVQIVSEG-----GAPAVIA
MUL_3812|M.ulcerans_Agy99 ESVWADPGRRAEVHRSAQTVADLLAQAGFDDVQIVSEG-----GAPAVIA
Mb2551c|M.bovis_AF2122/97 ESVWADPDRRDEVHRSARAVADLLSQAGFDDVRIVSER-----GAPAVIA
Rv2522c|M.tuberculosis_H37Rv ESVWADPDRRDEVHRSARAVADLLSQAGFDDVRIVSER-----GAPAVIA
MLBr_01193|M.leprae_Br4923 ESVWADPGRRNEVHRSAQVVLDLLSQAGFNFVRIVSEG-----GAPAVIA
MAV_1652|M.avium_104 ESVWADPGRRSEVQRSARAVADLLAQAGFGDVRIVSEG-----GAPAVIA
MAB_2311|M.abscessus_ATCC_1997 LVETNTTASQGSCTEAAQKMAARLKGAGYADKDLVFFSPPDHPKDGGLVA
Mvan_4122|M.vanbaalenii_PYR-1 HHPAPEGAPTVLLYAHHDVQPEGDPGQWHTAPFEPTERDGRLYGRGTADD
Mflv_2534|M.gilvum_PYR-GCK RHPAPEGAPTVLLYAHHDVQPEGDPAQWHTPPFEPTERGGRLYGRGTADD
MSMEG_4755|M.smegmatis_MC2_155 HHPAPSGAPTVLLYAHHDVQPEGDPAQWDSPPFEPTERDGRLYGRGTADD
TH_1101|M.thermoresistible__bu --------------------------------------------------
MMAR_3957|M.marinum_M QHPAPPGAPTVLLYAHHDVQPEGDPDQWASAPFEPTERDGRLYGRGTADD
MUL_3812|M.ulcerans_Agy99 QHPAPPGAPTALLYAHHDVQPEGDPDQWASAPFEPTERDGRLYGRGTADD
Mb2551c|M.bovis_AF2122/97 RYPAPPGAPTVLLYAHHDVQPEGDRGQWVSPPFEPTERGGRLYGRGTADD
Rv2522c|M.tuberculosis_H37Rv RYPAPPGAPTVLLYAHHDVQPEGDRGQWVSPPFEPTERGGRLYGRGTADD
MLBr_01193|M.leprae_Br4923 RYPAPLGTPTVLLYAHHDVQPEGDRDQWASPPFEPTERDGRIYGRGSADD
MAV_1652|M.avium_104 RHPAPPGAPTVLLYAHHDVQPEGDRGQWVSPPFEPTERDGRLYGRGSADD
MAB_2311|M.abscessus_ATCC_1997 TLGGSDAAAKPILLLAHIDVVEAKREDWKRDPFTLAEDNGYFYARGAEDD
Mvan_4122|M.vanbaalenii_PYR-1 KAGIATHLAAFRAHGGNPPVG----VTVFVEGEEESGSPSLSRLLATHRE
Mflv_2534|M.gilvum_PYR-GCK KAGIATHLAAFRAHGGNPPVG----VTVFVEGEEESGSPSLSRLLAEHRD
MSMEG_4755|M.smegmatis_MC2_155 KAGIATHLAAVRAFDGKPPVG----VTVFVEGEEESGSPSLGALLAAHRD
TH_1101|M.thermoresistible__bu -------------------------VTVFVEGEEESGSPSLGRLLAAHRD
MMAR_3957|M.marinum_M KAGIATHLAAFRAHDGKPPVG----VTVFVEGEEESGSPSLGRLLAAHRD
MUL_3812|M.ulcerans_Agy99 KAGIATHLAAFRAHDGKPPVG----VTVFVEGEEESGSPSLGRLLAAHRD
Mb2551c|M.bovis_AF2122/97 KAGIATHVAAFWAHGGRPPVG----VTVFVEGEEESGSPSLGRLLAAHRD
Rv2522c|M.tuberculosis_H37Rv KAGIATHVAAFWAHGGRPPVG----VTVFVEGEEESGSPSLGRLLAAHRD
MLBr_01193|M.leprae_Br4923 KAGIATHLAAFRAHGGRPPVG----VTVFVEGEEESGSPSLGRLLAAHRD
MAV_1652|M.avium_104 KAGIATHLAAFRAHGGRPPVG----VTVFVEGEEESGSPSLGRLLAAQRD
MAB_2311|M.abscessus_ATCC_1997 KAMAAIFVDSLMRYRTENFVPKRPIRVALTCGEEGGGQVNGAEWLHQNRP
..:. *** .*. . . * :*
Mvan_4122|M.vanbaalenii_PYR-1 ALAADVIVIAD--SDNWSTDIPSLTVSLRG--LADCVVEVATLDHGLHSG
Mflv_2534|M.gilvum_PYR-GCK LLAADVIVIAD--SDNWSTEIPSLTVSLRG--LADCVVEVATLDHGLHSG
MSMEG_4755|M.smegmatis_MC2_155 ALAADVIIIAD--SDNWSTEQPALTVSLRG--LADCVVEVATLDHGLHSG
TH_1101|M.thermoresistible__bu ALAADVIIIAD--SDNWSTEVPALTVSLRG--LVDCVVEVATLDHGLHSG
MMAR_3957|M.marinum_M VLAADVIVIAD--SDNWSTDVPALTVSLRG--MADCVVEVATLDHGLHSG
MUL_3812|M.ulcerans_Agy99 VLAADVIVIAD--SDNWSTDVPALTVSLRG--MADCVVEVATLDHGLHSG
Mb2551c|M.bovis_AF2122/97 ALAADVIVIAD--SDNWSTDIPALTVSLRG--MADCVVEVATLDHGLHSG
Rv2522c|M.tuberculosis_H37Rv ALAADVIVIAD--SDNWSTDIPALTVSLRG--MADCVVEVATLDHGLHSG
MLBr_01193|M.leprae_Br4923 ALAADVIIIAD--SDNWSTDVPALTVSLRG--LVDCVVEVATLDHGLHSG
MAV_1652|M.avium_104 TLAADVIVIAD--SDNWSVDTPALTVSLRG--LVDCVVEVATLDHGLHSG
MAB_2311|M.abscessus_ATCC_1997 QLVDAEFVINEGAGGDLNEDNKPVLLEIQAGQKIYQDFTLEVTDEGGHSS
*. ::* : ..: . : .: :.::. . : . *.* **.
Mvan_4122|M.vanbaalenii_PYR-1 MWGGVVPDALSVLVRLLASLHDDDGNVAVEGLHEPVTAAADFPDYTPDRV
Mflv_2534|M.gilvum_PYR-GCK MWGGVVPDALTVLVRLLAGLHDDDGNVAVEGLHETDTADRDFPDYTPERV
MSMEG_4755|M.smegmatis_MC2_155 LWGGVVPDALSVLVRLLASLHDDEGNVAVEGLHEATAADVDR---GADWV
TH_1101|M.thermoresistible__bu LWGGVVPDALSVLVRLLASLHDDDGNVAVAGLHEATVADVDR---GPDWV
MMAR_3957|M.marinum_M LWGGVVPDALSVLVRLLASLHDDDGNVAVAGLHES---TAAAVDYPPERV
MUL_3812|M.ulcerans_Agy99 LWGGVVPDALSVLVRLLASLHDDDGNVAVAGLHES---TAAAVDYPPERV
Mb2551c|M.bovis_AF2122/97 LWGGVVPDALTVLVRLLASLHDDDGNVAVAGMHES---TAARVDYPAGRV
Rv2522c|M.tuberculosis_H37Rv LWGGVVPDALTVLVRLLASLHDDDGNVAVAGMHES---TAARVDYPAGRV
MLBr_01193|M.leprae_Br4923 LWGGVVPDALSVLMRLLASLHDDDGNVAVAGLHEST--TAADVNYPHERV
MAV_1652|M.avium_104 LWGGVVPDALSVLVRLLASLHDDDGNVAVAGLHETDIATLNYPDYPPERV
MAB_2311|M.abscessus_ATCC_1997 QPG--SFNAIQALGAALNRLAATPFPVQLNDITRAY-FKAQAPLRPGEVG
* :*: .* * * * : .: ..
Mvan_4122|M.vanbaalenii_PYR-1 RADTGLLDGVREIGSGSVAQRLWAKPAITVIGIDTTPIA--QASNTLIAR
Mflv_2534|M.gilvum_PYR-GCK RSDTGVLDGVTEIGSGSVAQRLWAKPAITVVGIDTTPIA--KASNTLIPR
MSMEG_4755|M.smegmatis_MC2_155 RQESGLLDGVSEIGSGSVVQRMWAKPAVTVIGIDTTPIG--KSSNTLIPR
TH_1101|M.thermoresistible__bu RAEAGLLDGVRQIGTGTVAQRLWAKPAITVIGIDTTPIA--AASNTLIPR
MMAR_3957|M.marinum_M RADSGLLDGVTEIGSGSVPQRLWAKPAITVIGIDTTSIA--AASNTLIPR
MUL_3812|M.ulcerans_Agy99 RADSGLLDGVTEIGSGSVPQRLWAKPAITVIGIDTTSIA--AASNTLIPR
Mb2551c|M.bovis_AF2122/97 RAESGLLDGVSEIGTGSVPQRLWAKPAITVIGIDTTSVA--AASNTLIPR
Rv2522c|M.tuberculosis_H37Rv RAESGLLDGVSEIGTGSVPQRLWAKPAITVIGIDTTSVA--AASNTLIPR
MLBr_01193|M.leprae_Br4923 RADSGLLDGVSEIGSGSVPQRLWAKPAITVIGIDTTSVA--AASNMLIPR
MAV_1652|M.avium_104 RADSGVLPGVSEIGSGSVPQRLWAKPAITVIGIDATPVE--RASNTLIPR
MAB_2311|M.abscessus_ATCC_1997 QAMSTIVANPQDPAAVAVLSRNPLYNAMLRTTCVPTKIEGGHANNALPQR
: : :: . : .: :* .* *: .* : :.* * *
Mvan_4122|M.vanbaalenii_PYR-1 ARAKVSMRVAPGGDAAAHLAALTRHLEGHAPWGAKVTVTPGDVGEPYAIA
Mflv_2534|M.gilvum_PYR-GCK ARAKVSMRVAPGGDAAAHLAALTRHLESRAPWGAQVTVTPGDVGEPYAID
MSMEG_4755|M.smegmatis_MC2_155 ARAKISMRVAPGGDARAHLEALTRHLEANTPWGAKVTVTPGDIGQPYAID
TH_1101|M.thermoresistible__bu ARAKISMRVAPGGDARAHLDALTRHLHEHTPWGAHVTVTPGEIGEPYAID
MMAR_3957|M.marinum_M ARAKISIRIAPGGDAAAHLDAVEAHLRKHAPWGARVSVERGDIGQPYAID
MUL_3812|M.ulcerans_Agy99 ARAKISIRIAPGGDAAAHLDAVEAHLRKHAPWGARVSVERGDIGQPYAID
Mb2551c|M.bovis_AF2122/97 ARAKISIRVAPGGDATAHLDAVEAHLRRHAPWGAQVTVTRGEVGQPYAIE
Rv2522c|M.tuberculosis_H37Rv ARAKISIRVAPGGDATAHLDAVEAHLRRHAPWGAQVTVTRGEVGQPYAIE
MLBr_01193|M.leprae_Br4923 ARAKISMRIAPGGDAAVHLDALTAHLQRYAPWGAQVSVIRGEVSQPYAIE
MAV_1652|M.avium_104 ARAKISMRVAPGGDAAAHLDALTAHLQQHAPWGAQVSVTRGDIGEPYAID
MAB_2311|M.abscessus_ATCC_1997 ATANVNCRILPGPGSVQQGAQDAIVKAVNDPKITVKPAAPFRANVASVPP
* *::. *: ** .: : * : .. . . .
Mvan_4122|M.vanbaalenii_PYR-1 ASGPVYDAARSAFREAWGHDAVDTGVGGSIPFIAEFAAAFPDAKILVTGV
Mflv_2534|M.gilvum_PYR-GCK AAGPVYDAVRDVFRQAWGRDGVDTGVGGSIPFIAEFAAAFPEAKILVTGV
MSMEG_4755|M.smegmatis_MC2_155 ASGPVYDAARAAFGKAWGHEPVDMGMGGSIPFIAEFAAAFPDATILVTGV
TH_1101|M.thermoresistible__bu ADGPVYDAARAAFREAWGREPVDMGMGGSIPFIAEFAAAFPDATILVTGV
MMAR_3957|M.marinum_M ASGPVYDAARTAFRQAWGADPIDMGMGGSIPFIAEFAEAFPDAKILVTGV
MUL_3812|M.ulcerans_Agy99 ASGPVYDAARTAFRQAWGADPIDMGMGGSIPFIAEFAEAFPDAKILVTGV
Mb2551c|M.bovis_AF2122/97 ASGPVYDAARSAFRQAWGADPIDMGMGGSIPFIAEFAAAFPQATILVTGV
Rv2522c|M.tuberculosis_H37Rv ASGPVYDAARSAFRQAWGADPIDMGMGGSIPFIAEFAAAFPQATILVTGV
MLBr_01193|M.leprae_Br4923 ASGGVYDTARTAFRQAWGADPTDMGMGGSIPFIAEFASAFPQAKILVTGV
MAV_1652|M.avium_104 ASGSVYDAARAAFRQAWGTEPIDMGMGGSIPFIAEFAAAFPEAKILVTGV
MAB_2311|M.abscessus_ATCC_1997 LTPQIVDPIKAVAGAMWPGVPLVPTMS-TGATDAIYFGRTPVYGLSGIFA
: *. : . * :. : . * : * : .
Mvan_4122|M.vanbaalenii_PYR-1 EDPDTQAHSINESLHLGVLERAATAEALLLARLGGSDGQPAS-
Mflv_2534|M.gilvum_PYR-GCK EDPDTQAHSINESLHLGVLERAATAEALLLGRLGDLDGQVAS-
MSMEG_4755|M.smegmatis_MC2_155 EDPGTQAHSINESLHLGVFEKAATAEALLLDALGR--------
TH_1101|M.thermoresistible__bu EDPGTQAHSVNESLHLGVLQRAATAEALLLARLGG--------
MMAR_3957|M.marinum_M EDPGTQAHSVNESLHLGVLERAAVAEALLLANLA---------
MUL_3812|M.ulcerans_Agy99 EDPGTQAHSVNESLHLGVLERAAVAEALLLANLA---------
Mb2551c|M.bovis_AF2122/97 EDPGTQAHSVNESLHLGVLERAATAEALLLAKLAAIPTGRAEA
Rv2522c|M.tuberculosis_H37Rv EDPGTQAHSVNESLHLGVLERAATAEALLLAKLAAIPTGRAEA
MLBr_01193|M.leprae_Br4923 GDPATQAHGVNESVHLGVLERAAVAEALLLANLA---------
MAV_1652|M.avium_104 EDPATQAHSINESLHLGVLERAAISEALLLANLADLADLPNPG
MAB_2311|M.abscessus_ATCC_1997 QPGETHAHGLDERIQVKSLYDGRAFLYQVVKLYANGA------
*:**.::* ::: : . :: .