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VVIGGGRFRLKQRADPVAGPHEVLVEVRAAGLNAADLQQARGDYPAPAGWPADVPGLEIAGEVIDVGASV TGVAVADGVMALVGGGGHAERLAVPADLLLPIPRDVSWEQAGGFPEIFSTAWDALVTQAQVGVGDRVLIT GAAGGVGSAMVQIAAVTGAHVVASVRRPELHAKVKSLGGESQSLTVVSPDDEADDGPFDVIVELVGGADC LQRVELLRTGGRFLIVGVHTGATASLPMFTLMLARAKLIGTTIRGRSHAEKALLARTIAGKVVPLLADGR IRVPIEATYGLDDYADAYERLGAPGKFGKIVLTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3306 | - | - | 100% (314) | zinc-binding alcohol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6362 | - | 3e-43 | 35.22% (301) | quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_0097 | - | 6e-26 | 31.21% (314) | oxidoreductase, zinc-binding dehydrogenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3806 | - | 6e-49 | 36.77% (310) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1189 | - | 1e-44 | 33.55% (307) | alcohol dehydrogenase |
| M. tuberculosis H37Rv | Rv3777 | - | 2e-48 | 36.45% (310) | oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 5e-46 | 34.42% (308) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_0207c | - | 1e-42 | 32.70% (318) | quinone oxidoreductase |
| M. marinum M | MMAR_5332 | - | 5e-47 | 35.35% (314) | oxidoreductase |
| M. avium 104 | MAV_0242 | - | 6e-51 | 39.16% (309) | quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_1665 | - | 6e-46 | 35.74% (305) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_0096 | - | 3e-47 | 35.67% (314) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5615 | - | 4e-42 | 33.99% (306) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00118|M.leprae_Br4923 ---MHAIVAESA---NQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQV
MAV_0242|M.avium_104 MATMRAIVAESA---DQLSWQEVADVSAGPGEVVVKVAAAGVNRADVLQA
Mb3806|M.bovis_AF2122/97 MTIMRAVVAESS---DRLVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
Rv3777|M.tuberculosis_H37Rv MTIMRAVVAESS---DRLVWQEVPDVSAGPGEVLIKVAASGVNRADVLQA
MMAR_5332|M.marinum_M MAFVHAIVAESA---DHLVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
MUL_0096|M.ulcerans_Agy99 MAFVHAIVAESA---DHLVWQQVPDVTAGAGEVVIKVAAAGVNRADVLQA
Mflv_1189|M.gilvum_PYR-GCK -------MAETP---DQLNWQSVPDPTPGPGEVLIRVHAAGVNRADLLQA
Mvan_5615|M.vanbaalenii_PYR-1 --MHAIVAQPSS---EGLTWQSVPDIAPAPGEVLIRVAAAGVNRADLLQA
TH_1665|M.thermoresistible__bu ---MRAISVQTS---GQLSWVEVPDIEPGESEVLIAVHTAGINRADLLQA
MAB_0207c|M.abscessus_ATCC_199 ---MHAITVDNPGGPEALRWTEVPDPVPGPGEILIDVTAAAANRADLLQR
MSMEG_3306|M.smegmatis_MC2_155 ------MVIGGG----RFRLKQRADPVAGPHEVLVEVRAAGLNAADLQQA
: . .* .. *::: * ::. * **: *
MLBr_00118|M.leprae_Br4923 AGKYPHPPG-ASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGGYAE
MAV_0242|M.avium_104 AGKYPPPPG-ASETIGMEVSGVIAEVGDGVTEWSVGQEVCALLAGGGYAE
Mb3806|M.bovis_AF2122/97 AGKYPPPPG-VSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAE
Rv3777|M.tuberculosis_H37Rv AGKYPPPPG-VSDIIGLEVSGIVAAVGPGVTEWSAGQEVCALLAGGGYAE
MMAR_5332|M.marinum_M AGKYPPPPG-ASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAE
MUL_0096|M.ulcerans_Agy99 AGKYPPPPG-ASEIIGMEVSGTITDIGDGVTEWSAGQEVCALLAGGGYAE
Mflv_1189|M.gilvum_PYR-GCK AGKYPPPPG-ASEIIGLEASGTIAAVGDGVTEWSEGQRVCALLAGGGYAE
Mvan_5615|M.vanbaalenii_PYR-1 AGKYPPPPG-ASDILGLEVSGTIAAIGEGVTKWSQGQPVCALLAGGGYAE
TH_1665|M.thermoresistible__bu AGKYPPPPG-ASEILGLEVSGTVAAVGAGVSGWTVGQPVCALLAGGGYAE
MAB_0207c|M.abscessus_ATCC_199 RGLYSPPPG-ASSILGLECSGTVAALGADVAHWSVGQPVCALLSGGGYAE
MSMEG_3306|M.smegmatis_MC2_155 RGDYPAPAGWPADVPGLEIAGEVIDVGASVTGVAVADGVMALVGGGGHAE
* *. *.* : *:* :* : :. .*: : .: * **:.***:**
MLBr_00118|M.leprae_Br4923 YVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLH
MAV_0242|M.avium_104 YVAVPAGQLLPIPAGVDLVDAAGLPEVACTVWSNLVLIAGLRNGQLLLVH
Mb3806|M.bovis_AF2122/97 YVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIH
Rv3777|M.tuberculosis_H37Rv YVAVPADQVLPIPPSVNLVDSAALPEVACTVWSNLVMTAHLRPGQLVLIH
MMAR_5332|M.marinum_M YVAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIH
MUL_0096|M.ulcerans_Agy99 YVAVPAGQVLPMPPGVSLIDAAALPEVACTVWSNLVMTAHLGPGQLVLIH
Mflv_1189|M.gilvum_PYR-GCK YVAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNLVMTARLRAPELLLIH
Mvan_5615|M.vanbaalenii_PYR-1 FVAVPAGQVLPIPDGVPVPHAAGLPEVACTVWSNVVMAAGLTAPELLLVH
TH_1665|M.thermoresistible__bu YVAVPAEQVMPIPESVEIRYAAALPEVACTVWSNLVMTAGLSAGEWVLIH
MAB_0207c|M.abscessus_ATCC_199 KVVAPATQLLPVPTNVQLDVAAALPEVACTVWSNMMMTTKMSAGQSILIH
MSMEG_3306|M.smegmatis_MC2_155 RLAVPADLLLPIPRDVSWEQAGGFPEIFSTAWDALVTQAQVGVGDRVLIT
:..** ::*:* .* :..:**: .*.*. :: : : : :*:
MLBr_00118|M.leprae_Br4923 GGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRDEDF
MAV_0242|M.avium_104 GGASGIGSHAIQVARALGARVAVTAGSAEKLGFCRELGADITINYRDEDF
Mb3806|M.bovis_AF2122/97 GGASGIGSHAIQVARALAARVAITAGSPEKLELCRDLGAQITINYRDEDF
Rv3777|M.tuberculosis_H37Rv GGASGIGSHAIQVVRALAARVAITAGSPEKLELCRDLGAQITINYRDEDF
MMAR_5332|M.marinum_M GGASGIGSHAIQVCTALGARVAVTAGSSEKLQLCRDLGAQITINYRDEDF
MUL_0096|M.ulcerans_Agy99 GGACGIGSHAIQVCTALGARVAVTAGSSEKLQLSRDLGAQITINYRDEDF
Mflv_1189|M.gilvum_PYR-GCK GGASGIGTHAIQVARALNCRVAVTAGSRNKLDLCAELGAEITIDYHHEDF
Mvan_5615|M.vanbaalenii_PYR-1 GGASGIGTHAIQVAKALNCRVAVTAGSRNKLDLCAELGADITIDYHNEDY
TH_1665|M.thermoresistible__bu GGASGVGSHAVQVARALDARVAVTAGTRHKLELCRELGAEVTICYREEDF
MAB_0207c|M.abscessus_ATCC_199 GGASGIGTHTIQVAKALGLRVAVTAGTPEKLDACRDLGADLAINYRDTDF
MSMEG_3306|M.smegmatis_MC2_155 GAAGGVGSAMVQIAAVTGAHVVASVRRPELHAKVKSLGGES----QSLTV
*.: *:*: :*: . :*. :. . **.: :
MLBr_00118|M.leprae_Br4923 VARLQQQN---GGADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVKG
MAV_0242|M.avium_104 VARLADET---GGADVILDIMGAAYLDRNIDALATDGQLVIIGMQGGVKA
Mb3806|M.bovis_AF2122/97 VARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKA
Rv3777|M.tuberculosis_H37Rv VARLKQETDG-SGADIILDIMGASYLDRNIDALATDGQLIVIGMQGGVKA
MMAR_5332|M.marinum_M VARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKA
MUL_0096|M.ulcerans_Agy99 VARLKQETDG-SGADVILDIMGAAYLDRNVDALAVDGQLVIIGMQGGIKA
Mflv_1189|M.gilvum_PYR-GCK VEVLRGADSDHPGADVILDIMGASYLDRNIDALATGGRLVIIGMQGGTKA
Mvan_5615|M.vanbaalenii_PYR-1 VGVVRDAG----GADVILDIMGAAYLDRNIETLADGGRLVIIGMQGGAKA
TH_1665|M.thermoresistible__bu VERVRAETDG-AGADVVLDIMGAAYLGRNVDALATDGRLVVIGMQGGRRA
MAB_0207c|M.abscessus_ATCC_199 VQAVHSFTDG-SGVDRILDIMGAKYLSRNVDALGNDGHLVIIGMQGGVTA
MSMEG_3306|M.smegmatis_MC2_155 VSPDDEADDG--PFDVIVELVGGADCLQRVELLRTGGRFLIVGVHTGATA
* * :::::*. :.:: * .*:::::*:: * .
MLBr_00118|M.leprae_Br4923 ELNLGKVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSV
MAV_0242|M.avium_104 ELNIGKLLAKRARVIGTTLRGRPVSGPNSKTEIVQAVTASVWPMIADGRV
Mb3806|M.bovis_AF2122/97 ELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRV
Rv3777|M.tuberculosis_H37Rv ELNLGKLLTKRARVIGTTLRARPVSGPHGKAAIAQAVAASVWPMIAANRV
MMAR_5332|M.marinum_M ELNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRV
MUL_0096|M.ulcerans_Agy99 ELNLGKLLTKRARVIGTTLRARPLQGPNGKAVIAQAVTASVWPMIASNRV
Mflv_1189|M.gilvum_PYR-GCK EINLGKLLAKRGSVMATALRSRPVTGRGSKSVIVSEVIENVWPLVADGQV
Mvan_5615|M.vanbaalenii_PYR-1 ELNIGKLLTKRGSVIATALRSRPVHGRGGKADIVARVGAELWPLVADGQV
TH_1665|M.thermoresistible__bu ELDLGKLVAKRAAVFGTALRGRPVTGPHGKADIVRAVVENVWPMVASDQV
MAB_0207c|M.abscessus_ATCC_199 ELNIAKLIAKRGSLTATTLRARPIAGPCGKAAIVESVAQNLWPLVEAGKV
MSMEG_3306|M.smegmatis_MC2_155 SLPMFTLMLARAKLIGTTIRGR---SHAEKALLARTIAGKVVPLLADGRI
.: : .:: *. : .:::*.* . *: :. : .: *:: . :
MLBr_00118|M.leprae_Br4923 RPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
MAV_0242|M.avium_104 RPIIGARLPIQQAGDAHRRLVASEVTGKIVLTV-------------
Mb3806|M.bovis_AF2122/97 RPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
Rv3777|M.tuberculosis_H37Rv RPVIGTRLPIQQAAQAHELMLSGKTFGKILLTV-------------
MMAR_5332|M.marinum_M RPIIGSRLPIGQAAQAHQLLLSGQSYGKTLLTVDG-----------
MUL_0096|M.ulcerans_Agy99 RPIIGSRLPIGQAAQAHQLLLSGQSYGKILLTVDG-----------
Mflv_1189|M.gilvum_PYR-GCK RPVIGAEFPISEAQAAHELLASGDVSGKVILRVDV-----------
Mvan_5615|M.vanbaalenii_PYR-1 RPVIGAEFPIAEAQAAHELLASGDVSGKVLLRVDV-----------
TH_1665|M.thermoresistible__bu RPVVGAEFPIQEAQAAHELLASGDVYGKVLLCVED-----------
MAB_0207c|M.abscessus_ATCC_199 RPVVGAEIPLSQAAEAHRLLENGAVVGKVLLTR-------------
MSMEG_3306|M.smegmatis_MC2_155 RVPIEATYGLDDYADAYERLGAPGKFGKIVLTP-------------
* : : : : *:. : ** :*