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PTLLFERDVIPLIRALYPHAYRLTREHADAEDLLQETSVKAYRAFGSAVLVGEGTNLAGWLYRIMRNTHL SAYRRRLCRPALQFTGEVTGGVARSTEDVVLTAAGDPAVAAAMRALPEKYRTAVYYADVEGRTFREIAEL VDVPIGTVMSRLHRGRMRLRVALADVARDRGYPLFEAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1078 | - | - | 100% (179) | ECF subfamily RNA polymerase sigma-24 factor |
| M. gilvum PYR-GCK | Mflv_4689 | - | 1e-43 | 52.75% (182) | ECF subfamily RNA polymerase sigma-24 factor |
| M. gilvum PYR-GCK | Mflv_2200 | - | 5e-16 | 34.44% (151) | RNA polymerase sigma factor SigE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3250c | sigH | 5e-45 | 52.66% (188) | RNA polymerase sigma factor RpoE |
| M. tuberculosis H37Rv | Rv3223c | sigH | 5e-45 | 52.66% (188) | RNA polymerase sigma factor RpoE |
| M. leprae Br4923 | MLBr_01076 | sigE | 9e-18 | 35.37% (147) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_3543c | - | 7e-43 | 50.84% (179) | RNA polymerase sigma-E factor |
| M. marinum M | MMAR_1334 | sigH | 3e-45 | 52.66% (188) | alternative RNA polymerase sigma-E factor (sigma- 24) SigH |
| M. avium 104 | MAV_4171 | - | 1e-43 | 52.20% (182) | RNA polymerase sigma factor RpoE |
| M. smegmatis MC2 155 | MSMEG_1914 | - | 1e-44 | 53.30% (182) | RNA polymerase sigma-70 factor, family protein |
| M. thermoresistible (build 8) | TH_0665 | sigH | 3e-44 | 54.14% (181) | ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH |
| M. ulcerans Agy99 | MUL_2545 | sigH | 1e-45 | 52.66% (188) | RNA polymerase sigma factor RpoE |
| M. vanbaalenii PYR-1 | Mvan_5744 | - | 1e-64 | 68.11% (185) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1078|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5744|M.vanbaalenii_PYR-1 ------------------------------------MHT-----------
MSMEG_1914|M.smegmatis_MC2_155 ------------------------------------MFPTMTD----VDR
TH_0665|M.thermoresistible__bu ----------------------------------------MTD----IEG
Mb3250c|M.bovis_AF2122/97 ----------------------------------------MAD----IDG
Rv3223c|M.tuberculosis_H37Rv ----------------------------------------MAD----IDG
MMAR_1334|M.marinum_M -MSTSTSLLGEERLGRFPASPASVATLSGGTSTEGTVFIKMAD----IDG
MUL_2545|M.ulcerans_Agy99 ----------------------------------------MAD----IDG
MAV_4171|M.avium_104 MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDG
MAB_3543c|M.abscessus_ATCC_199 -----------------------MACLERPMSVP-IRMVGVATERTAVTS
MLBr_01076|M.leprae_Br4923 -MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSP
Mflv_1078|M.gilvum_PYR-GCK -------------------------MPTLLFERDVIP--------LIRAL
Mvan_5744|M.vanbaalenii_PYR-1 --------------------DRHDDQLTDRFERDAMP--------LIADL
MSMEG_1914|M.smegmatis_MC2_155 VEPETPPER-----------EETDAELTARFERDAIP--------LLDQL
TH_0665|M.thermoresistible__bu ---TTPIRS-----------EESDAELTARFERDAIP--------LLDQL
Mb3250c|M.bovis_AF2122/97 VTGSAGLQP--------GPSEETDEELTARFERDAIP--------LLDQL
Rv3223c|M.tuberculosis_H37Rv VTGSAGLQP--------GPSEETDEELTARFERDAIP--------LLDQL
MMAR_1334|M.marinum_M VTLAEAPDP--------EPPEETDEQLTARFERDAIP--------LLDQL
MUL_2545|M.ulcerans_Agy99 VTLAEAPDP--------EPPEETDEQLTACFERDAIP--------LLDQL
MAV_4171|M.avium_104 VTSPEVPEAHAEPAAHEETREETDAELTARFERDAIP--------LLDQL
MAB_3543c|M.abscessus_ATCC_199 MDSAAELPG--------LVHVETEAERVARFERDALP--------LLDQL
MLBr_01076|M.leprae_Br4923 TIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARV
:: .:* :
Mflv_1078|M.gilvum_PYR-GCK YPHAYRLTREHADAEDLLQETSVKAYRAFGSAVLVGEGTNLAGWLYRIMR
Mvan_5744|M.vanbaalenii_PYR-1 YRHAIRLTRDHADAEDLLQETAAKAYAAFAS---FQEGTNLVGWLYRIMV
MSMEG_1914|M.smegmatis_MC2_155 YGGALRMTRNPADAEDLLQETMVKAYAGFRS---FREGTNLKAWLYRILT
TH_0665|M.thermoresistible__bu YGGALRMTRNPADAEDLLQETMVKAYQGFRS---FREGTNLKAWLYRILT
Mb3250c|M.bovis_AF2122/97 YGGALRMTRNPADAEDLLQETMVKAYAGFRS---FRHGTNLKAWLYRILT
Rv3223c|M.tuberculosis_H37Rv YGGALRMTRNPADAEDLLQETMVKAYAGFRS---FRHGTNLKAWLYRILT
MMAR_1334|M.marinum_M YGGALRMTRNPADAEDLLQETMVKAYAGFRS---FREGTNLKAWLYRILT
MUL_2545|M.ulcerans_Agy99 YGGALRMTRNPADAEDLLQETMVKAYAGFRS---FREGTNLKAWLYRILT
MAV_4171|M.avium_104 YGGALRMTRNPADAEDLLQETMVKAYAGFRS---FRAGTNLKAWLYRILT
MAB_3543c|M.abscessus_ATCC_199 YGAALRMTRNPADAEDLVQETMVKAYAGFGT---FKEGTNLKAWLYRILT
MLBr_01076|M.leprae_Br4923 YWLAYRLSGNQHDAEDLTQETFIRVFRSVQN---YQPGT-FEGWLHRITT
* * *:: : ***** *** :.: .. . ** : .**:**
Mflv_1078|M.gilvum_PYR-GCK NTHLSAYRRRLCRPALQFTGEVTGG-----------VARSTEDVVLTAAG
Mvan_5744|M.vanbaalenii_PYR-1 NTHISAYRRQQHRPTLQFTDEFTDGQLLAHSQRGSSATRSTEELAIAHTG
MSMEG_1914|M.smegmatis_MC2_155 NTYINSYRKKQRQPSEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALP
TH_0665|M.thermoresistible__bu NTYINNYRKRQRQPAVYPTEEFTDWQLASTAEHSSTGLRSAEVEALEALP
Mb3250c|M.bovis_AF2122/97 NTYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALP
Rv3223c|M.tuberculosis_H37Rv NTYINSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALP
MMAR_1334|M.marinum_M NTYINSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALP
MUL_2545|M.ulcerans_Agy99 NTYINSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALP
MAV_4171|M.avium_104 NTYINSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSAEVEALESLP
MAB_3543c|M.abscessus_ATCC_199 NTYINIYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEIEALDGLP
MLBr_01076|M.leprae_Br4923 NLFLDMVRRRARIRMDALPDDYDRVP---------ADEPNPEQIYHDSRL
* .:. *:: . : ..*
Mflv_1078|M.gilvum_PYR-GCK DPAVAAAMRALPEKYRTAVYYADVEGRTFREIAELVDVPIGTVMSRLHRG
Mvan_5744|M.vanbaalenii_PYR-1 DPAIAAAMRSLPEKYRTAIYYADIEGRKFREIALLTNVPIGTVMSRLHRG
MSMEG_1914|M.smegmatis_MC2_155 DTEIKAALQALPEEFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRG
TH_0665|M.thermoresistible__bu DTEIKAALQELPEDFRIAVYLADVEGFPYKEIAEIMDTPIGTVMSRLHRG
Mb3250c|M.bovis_AF2122/97 DTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRG
Rv3223c|M.tuberculosis_H37Rv DTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRG
MMAR_1334|M.marinum_M DTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRG
MUL_2545|M.ulcerans_Agy99 DTEIKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRG
MAV_4171|M.avium_104 DSEIKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRG
MAB_3543c|M.abscessus_ATCC_199 DDEIKEALNKLPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRG
MLBr_01076|M.leprae_Br4923 GPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRG
. : *: ** .:* *: .*:** :.**. . :*** **:***
Mflv_1078|M.gilvum_PYR-GCK RMRLRVALADVARDRGYPLFEAA--------
Mvan_5744|M.vanbaalenii_PYR-1 RKQLRDALSDVARDRGYPLPEAA--------
MSMEG_1914|M.smegmatis_MC2_155 RRQLRDLLAGVARDRGFIRGPQLGEPEEVTS
TH_0665|M.thermoresistible__bu RRQLRSLLADVARERGIIRDQQAGTPEEVSS
Mb3250c|M.bovis_AF2122/97 RRQLRGLLADVARDRGFARGEQAH--EGVSS
Rv3223c|M.tuberculosis_H37Rv RRQLRGLLADVARDRGFARGEQAH--EGVSS
MMAR_1334|M.marinum_M RRQLRTLLADVAKERGFVRGEQAH--QEVSS
MUL_2545|M.ulcerans_Agy99 RRQLRTLLADVAKERGFVRGEQAH--QEVSS
MAV_4171|M.avium_104 RRQLRGLLADVAKERGFNRGQQTH--EEVSS
MAB_3543c|M.abscessus_ATCC_199 RRQLRDLLSEVAKDRGFLRNNELA--EGRA-
MLBr_01076|M.leprae_Br4923 RQALRDYLLTAHPRDGATTDATHVKSA----
* ** * . *