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MWRFAVVLAASGALTLSACASGEGGGESSPESTQAASGAKVDEIANTLPEDIKSSGKLIVGVNIPYAPNE FKDPSGKIVGFDVDLMNAVAATLGLTPEYREADFAKIIPSIQGGTFNVGMSSFTDTKEREQSVDFVTYFS AGSLWAQRVGGGIDPENACGKKVAVQATTVQETDELPARSKKCTDAGQPAIEIVPFDGQDAATNAVVLGQ VDAMSADSPVTLYAIKQSNGKLEKAGEVFDSAPYGWPVAKGSPLAQSLQQALQHLIDNGEYEKIAANWGL EDGTIDKPAINGAVS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3235 | - | - | 100% (295) | ABC-type amino acid transport system, secreted component |
M. smegmatis MC2 155 | MSMEG_1200 | - | 2e-88 | 59.77% (266) | serine/threonine-protein kinase PknD |
M. smegmatis MC2 155 | MSMEG_6595 | - | 1e-37 | 33.22% (304) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0419c | glnH | 2e-10 | 24.48% (241) | glutamine-binding lipoprotein |
M. gilvum PYR-GCK | Mflv_3583 | - | 1e-134 | 77.29% (295) | extracellular solute-binding protein |
M. tuberculosis H37Rv | Rv0411c | glnH | 2e-10 | 24.48% (241) | glutamine-binding lipoprotein |
M. leprae Br4923 | MLBr_00303 | glnH | 1e-09 | 23.87% (243) | putative glutamine-binding protein |
M. abscessus ATCC 19977 | MAB_4236c | - | 8e-25 | 29.08% (306) | amino acid ABC transporter substrate-binding protein |
M. marinum M | MMAR_0714 | glnH | 5e-11 | 25.31% (241) | glutamine-binding lipoprotein GlnH |
M. avium 104 | MAV_0059 | - | 6e-13 | 25.47% (267) | amino acid ABC transporter, permease protein, |
M. thermoresistible (build 8) | TH_0053 | - | 7e-79 | 59.13% (230) | ABC-type amino acid transport system, secreted component |
M. ulcerans Agy99 | MUL_2809 | glnH | 4e-11 | 25.31% (241) | glutamine-binding lipoprotein GlnH |
M. vanbaalenii PYR-1 | Mvan_2832 | - | 1e-136 | 81.69% (295) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0714|M.marinum_M -MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTPVGME MUL_2809|M.ulcerans_Agy99 -MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTPVGME Mb0419c|M.bovis_AF2122/97 -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME Rv0411c|M.tuberculosis_H37Rv -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME MLBr_00303|M.leprae_Br4923 MMTRQFKIQRACS---VLATAMMLAACGHAELLTVASMPTLPPPTPVGME Mflv_3583|M.gilvum_PYR-GCK -----MLGGIQGRQTRLWRVVAVFAATGAMALSGCSSS------------ Mvan_2832|M.vanbaalenii_PYR-1 -----MVAGIQDRRTRIWRVAAVFAAVGALALSGCSSS------------ MSMEG_3235|M.smegmatis_MC2_155 ----------------MWRFAVVLAASGALTLSACASG------------ TH_0053|M.thermoresistible__bu -------------------------------------------------- MAB_4236c|M.abscessus_ATCC_199 -----------------MRFLTVLVCTALTVLAGCAEG------------ MAV_0059|M.avium_104 -----MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPK MMAR_0714|M.marinum_M VMPPEPPLPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGRLIVGLD MUL_2809|M.ulcerans_Agy99 VMPPEPPLPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGRLIVGLD Mb0419c|M.bovis_AF2122/97 IMPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGLD Rv0411c|M.tuberculosis_H37Rv IMPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGLD MLBr_00303|M.leprae_Br4923 QVPPELLLPQDNTEEDCDPTASLRPFPTKAEADAAVAEIRARGRLIVGLE Mflv_3583|M.gilvum_PYR-GCK ---------SESPSDEGSPTAVAPAEKVDAIANTVPESIKSTGTLVVGVN Mvan_2832|M.vanbaalenii_PYR-1 ---------SEEPVEEGSPTAAAPAEKVDAIANTVPEAIKSTGKLIVGVN MSMEG_3235|M.smegmatis_MC2_155 ---------EGGGESSPESTQAASGAKVDEIANTLPEDIKSSGKLIVGVN TH_0053|M.thermoresistible__bu -------------------------------------------------- MAB_4236c|M.abscessus_ATCC_199 ------AAPGSSSFNLSPDQDRVRVAKVDAIAAEVPEGIRKRGTLVVTGD MAV_0059|M.avium_104 SAAVLPENLTRGGSMSQPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGTL MMAR_0714|M.marinum_M IGSNL-FSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRILSAAERI MUL_2809|M.ulcerans_Agy99 IGSNL-FSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRILSAAERI Mb0419c|M.bovis_AF2122/97 IGSNL-FSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV Rv0411c|M.tuberculosis_H37Rv IGSNL-FSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV MLBr_00303|M.leprae_Br4923 IGSNL-FSFRDPITGEITGFDIDIAGEVARDIFGTPSHMEYRILSTAARI Mflv_3583|M.gilvum_PYR-GCK VPYAP-NEFKDPE-GKLVGFDVDLMNAIAGTLGLTP---EYKEADFAKII Mvan_2832|M.vanbaalenii_PYR-1 IPYAP-NEFKDES-GKIVGFDVDLMNAIAGTLGLTP---EYREADFAKII MSMEG_3235|M.smegmatis_MC2_155 IPYAP-NEFKDPS-GKIVGFDVDLMNAVAATLGLTP---EYREADFAKII TH_0053|M.thermoresistible__bu VPYKP-NEFKNAA-GEIVGFDVDLMNAVARTLGLAP---EYRELPFEAIL MAB_4236c|M.abscessus_ATCC_199 ANSSPPLRFYADDDKTMIGIETDIAYLVADILGLRV---DLRSADWAQNF MAV_0059|M.avium_104 SGAPP--NVCITPTGQYSGFDNQLLRAIAGKLGLQVR---FVGTDFAGLL . *:: :: :* : . MMAR_0714|M.marinum_M TALQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRDSPIFK-V MUL_2809|M.ulcerans_Agy99 TALQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRDSPIFK-V Mb0419c|M.bovis_AF2122/97 TALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDSPITK-V Rv0411c|M.tuberculosis_H37Rv TALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDSPITK-V MLBr_00303|M.leprae_Br4923 TALQKSEVDIIVKTMTITCKRRKLVNFSTVYLDAKQRILAPRDSPITK-P Mflv_3583|M.gilvum_PYR-GCK PSIQGGTFDVGMSSFTDSKEREEQVDFVTYFSAG--TAWAQPAGGDIN-P Mvan_2832|M.vanbaalenii_PYR-1 PSIQGGTFNVGMSSFTDSKEREQQVDFVTYFSAG--TLWAQPAGGQID-P MSMEG_3235|M.smegmatis_MC2_155 PSIQGGTFNVGMSSFTDTKEREQSVDFVTYFSAG--SLWAQRVGGGID-P TH_0053|M.thermoresistible__bu PSVRAGDVHVGMASLTVTPERSAGADFVTYFQAG--TLWAQPAGGAVN-P MAB_4236c|M.abscessus_ATCC_199 VKVDSGEVDAFISNVTVTEERKEKFDFATYRLDNVTFEARRSLDWKVKGA MAV_0059|M.avium_104 AQVASRRFDVGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFT : .. ... : :* * . . . MMAR_0714|M.marinum_M SDLSGKRVCVARGTT---------SLRRIREIAPPPVIVSVVNWADCLVA MUL_2809|M.ulcerans_Agy99 SDLSGKRVCVARGTT---------SLRRIREIAPPPVIVSVVNWADCLVA Mb0419c|M.bovis_AF2122/97 SDLSGKRVCVARGTT---------SLRRIREIAPPPVIVSVVNWADCLVA Rv0411c|M.tuberculosis_H37Rv SDLSGKRVCVARGTT---------SLRRIREIAPPPVIVSVVNWADCLVA MLBr_00303|M.leprae_Br4923 SDLSNKRVCMTRGTT---------SLHQVSEVVPPPIIVSAENWADCLVA Mflv_3583|M.gilvum_PYR-GCK EDACGKKVAVQATTVQETDELPARSKKCVDEGKPAIEIIPFDSQDAATNA Mvan_2832|M.vanbaalenii_PYR-1 ENACGKKVAVQATTVQETDELPARSKKCTDAGQPAIEIIAFDSQDAATNA MSMEG_3235|M.smegmatis_MC2_155 ENACGKKVAVQATTVQETDELPARSKKCTDAGQPAIEIVPFDGQDAATNA TH_0053|M.thermoresistible__bu ADACGLRVGVAYATIQESDEVPFKSEICTAAGKPPIDKVVYVSQDDLTEA MAB_4236c|M.abscessus_ATCC_199 RDIAGKTIGVGSGTNQEALLVR-WNEENVAAGLPAADLKYFQQATGYYLA MAV_0059|M.avium_104 DLAAGQRIGVVQGTV----------EESYVVDTLHLQPVKYPDFATVYAS .. : : * : MMAR_0714|M.marinum_M LQQREIDAVSTDDTILAGLVEE-DPYLHIVGPNMANQPYG---IGINLDN MUL_2809|M.ulcerans_Agy99 LQQREIDAVSTDDTILAGLVEE-DPYLHIVGPNMANQPYG---IGINLDN Mb0419c|M.bovis_AF2122/97 LQQREIDAVSTDDTILAGLVEE-DPYLHIVGPDMADQPYG---VGINLDN Rv0411c|M.tuberculosis_H37Rv LQQREIDAVSTDDTILAGLVEE-DPYLHIVGPDMADQPYG---VGINLDN MLBr_00303|M.leprae_Br4923 MQQREIDAISTDDAILAGLVEE-DPYLHIVGPNMATQPYG---IGINLNN Mflv_3583|M.gilvum_PYR-GCK VVLGQADAMSADSPVTLYAIKQTNGKLEQAGETFDSAPYG---WPVEKGS Mvan_2832|M.vanbaalenii_PYR-1 VVLGQADAMSADSPVTLYAIKQTNGKLVQAGEVFDSAPYG---WPVEKGS MSMEG_3235|M.smegmatis_MC2_155 VVLGQVDAMSADSPVTLYAIKQSNGKLEKAGEVFDSAPYG---WPVAKGS TH_0053|M.thermoresistible__bu LMNGEIDAMSADSPVTGFAVKTSGGALQEAGEIFSPAPYG---WPVTRGS MAB_4236c|M.abscessus_ATCC_199 LASGRIDAYVGPNPSAVFHSEATGQTKLVGTFSGAGEALQGEIAVLTKKD MAV_0059|M.avium_104 LKTRQIDAWVAPAGQAATTIQPGDPAVVVANTISPGNFVA---YAVAKDN : . ** : . : . MMAR_0714|M.marinum_M TGLVRFVNGTLERIRNDGTWNTLYRKWLSVLGPAPAPPRPRYVD------ MUL_2809|M.ulcerans_Agy99 TGLVRFVNGTLERIRNDGTWNTLYRKWLSVLGPAPAPPRPRYVD------ Mb0419c|M.bovis_AF2122/97 TGLVRFVNGTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD------ Rv0411c|M.tuberculosis_H37Rv TGLVRFVNGTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD------ MLBr_00303|M.leprae_Br4923 TTLVRFVNGTLERIRRDGTWITLYRKWLTVLGPAPAPPTPRYVD------ Mflv_3583|M.gilvum_PYR-GCK P-LAQSLLQALQHLIDNGKYQEIAANWGLEEGMIDKPVINGAIS------ Mvan_2832|M.vanbaalenii_PYR-1 P-LAQSLLQALEHLIETGKYKEIAANWGLEEGMIDKPVINGAVS------ MSMEG_3235|M.smegmatis_MC2_155 P-LAQSLQQALQHLIDNGEYEKIAANWGLEDGTIDKPAINGAVS------ TH_0053|M.thermoresistible__bu P-LAESLRQALEHLIATGEYRTIATMWGVEKGMIDRPEINAAAG------ MAB_4236c|M.abscessus_ATCC_199 NGLVRAYADAINHAIADGTYRKVLQRWGLEDEAVAKSEINPRGLPRQG-- MAV_0059|M.avium_104 KPLVDALNSGLDAVIADGTWSNLYSQWVPRTLPPGWKPGSQAVAPPKLPD *. :: * : : * MMAR_0714|M.marinum_M -------------------------------------------------- MUL_2809|M.ulcerans_Agy99 -------------------------------------------------- Mb0419c|M.bovis_AF2122/97 -------------------------------------------------- Rv0411c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00303|M.leprae_Br4923 -------------------------------------------------- Mflv_3583|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2832|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3235|M.smegmatis_MC2_155 -------------------------------------------------- TH_0053|M.thermoresistible__bu -------------------------------------------------- MAB_4236c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0059|M.avium_104 FAAIAASQHHKAVGPAAPKSTLAQLRDSFFDWDMYRQAIPTLLRTGLPNT MMAR_0714|M.marinum_M -------------------------------------------------- MUL_2809|M.ulcerans_Agy99 -------------------------------------------------- Mb0419c|M.bovis_AF2122/97 -------------------------------------------------- Rv0411c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00303|M.leprae_Br4923 -------------------------------------------------- Mflv_3583|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2832|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3235|M.smegmatis_MC2_155 -------------------------------------------------- TH_0053|M.thermoresistible__bu -------------------------------------------------- MAB_4236c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0059|M.avium_104 LILTFSASVIGLVLGMVLAVAGISHARWLRWPARVYTDVFRGLPEVVIIL MMAR_0714|M.marinum_M -------------------------------------------------- MUL_2809|M.ulcerans_Agy99 -------------------------------------------------- Mb0419c|M.bovis_AF2122/97 -------------------------------------------------- Rv0411c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00303|M.leprae_Br4923 -------------------------------------------------- Mflv_3583|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2832|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3235|M.smegmatis_MC2_155 -------------------------------------------------- TH_0053|M.thermoresistible__bu -------------------------------------------------- MAB_4236c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0059|M.avium_104 LIGLGIGPIVGGLTNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQL MMAR_0714|M.marinum_M -------------------------------------------------- MUL_2809|M.ulcerans_Agy99 -------------------------------------------------- Mb0419c|M.bovis_AF2122/97 -------------------------------------------------- Rv0411c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00303|M.leprae_Br4923 -------------------------------------------------- Mflv_3583|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2832|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3235|M.smegmatis_MC2_155 -------------------------------------------------- TH_0053|M.thermoresistible__bu -------------------------------------------------- MAB_4236c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0059|M.avium_104 EASRALGFSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLV MMAR_0714|M.marinum_M -------------------------------------------------- MUL_2809|M.ulcerans_Agy99 -------------------------------------------------- Mb0419c|M.bovis_AF2122/97 -------------------------------------------------- Rv0411c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00303|M.leprae_Br4923 -------------------------------------------------- Mflv_3583|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2832|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3235|M.smegmatis_MC2_155 -------------------------------------------------- TH_0053|M.thermoresistible__bu -------------------------------------------------- MAB_4236c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_0059|M.avium_104 ADQRELFQVGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLRR MMAR_0714|M.marinum_M --------------------- MUL_2809|M.ulcerans_Agy99 --------------------- Mb0419c|M.bovis_AF2122/97 --------------------- Rv0411c|M.tuberculosis_H37Rv --------------------- MLBr_00303|M.leprae_Br4923 --------------------- Mflv_3583|M.gilvum_PYR-GCK --------------------- Mvan_2832|M.vanbaalenii_PYR-1 --------------------- MSMEG_3235|M.smegmatis_MC2_155 --------------------- TH_0053|M.thermoresistible__bu --------------------- MAB_4236c|M.abscessus_ATCC_199 --------------------- MAV_0059|M.avium_104 GRAAVDPEEPAEMLTFGQEIT