For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RFLTVLVCTALTVLAGCAEGAAPGSSSFNLSPDQDRVRVAKVDAIAAEVPEGIRKRGTLVVTGDANSSPP LRFYADDDKTMIGIETDIAYLVADILGLRVDLRSADWAQNFVKVDSGEVDAFISNVTVTEERKEKFDFAT YRLDNVTFEARRSLDWKVKGARDIAGKTIGVGSGTNQEALLVRWNEENVAAGLPAADLKYFQQATGYYLA LASGRIDAYVGPNPSAVFHSEATGQTKLVGTFSGAGEALQGEIAVLTKKDNGLVRAYADAINHAIADGTY RKVLQRWGLEDEAVAKSEINPRGLPRQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4236c | - | - | 100% (309) | amino acid ABC transporter substrate-binding protein |
| M. abscessus ATCC 19977 | MAB_0277c | - | 1e-11 | 23.16% (285) | amino acid ABC transporter permease |
| M. abscessus ATCC 19977 | MAB_4223 | - | 2e-06 | 30.67% (150) | glutamine-binding protein GlnH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0419c | glnH | 2e-06 | 31.65% (158) | glutamine-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_3583 | - | 4e-24 | 28.52% (305) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv0411c | glnH | 2e-06 | 31.65% (158) | glutamine-binding lipoprotein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0061 | glnQ | 6e-08 | 25.85% (236) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 9e-09 | 24.36% (275) | amino acid ABC transporter, permease protein, |
| M. smegmatis MC2 155 | MSMEG_6595 | - | 3e-27 | 28.43% (306) | secreted protein |
| M. thermoresistible (build 8) | TH_0053 | - | 4e-15 | 28.89% (225) | ABC-type amino acid transport system, secreted component |
| M. ulcerans Agy99 | MUL_2809 | glnH | 6e-07 | 31.65% (139) | glutamine-binding lipoprotein GlnH |
| M. vanbaalenii PYR-1 | Mvan_2832 | - | 3e-20 | 27.52% (298) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3583|M.gilvum_PYR-GCK -------------------------MLGGIQGRQTRLWRVVAVFAATGAM
Mvan_2832|M.vanbaalenii_PYR-1 -------------------------MVAGIQDRRTRIWRVAAVFAAVGAL
TH_0053|M.thermoresistible__bu --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGMEI
Rv0411c|M.tuberculosis_H37Rv MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGMEI
MUL_2809|M.ulcerans_Agy99 MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTPVGMEV
MMAR_0061|M.marinum_M ----------MLAVSATILIVLG--LALAAPALADHNQCAPAGVDSAMVL
MAV_0059|M.avium_104 MGRRGTRRGKLLALTATVLMVCGSSALLAPPAAADRNQCAPAGPKSAAVL
MSMEG_6595|M.smegmatis_MC2_155 -------------MPSTLRTRLSSRHRPGVLLAALLLTAGAAVACSAEDA
MAB_4236c|M.abscessus_ATCC_199 ----------------------------------MRFLTVLVCTALTVLA
Mflv_3583|M.gilvum_PYR-GCK ALSGCSSSSESPSDEGSPTAVAPAEKVDAIANTVPESIKSTGTLVVG-VN
Mvan_2832|M.vanbaalenii_PYR-1 ALSGCSSSSEEPVEEGSPTAAAPAEKVDAIANTVPEAIKSTGKLIVG-VN
TH_0053|M.thermoresistible__bu --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 MPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVG-LD
Rv0411c|M.tuberculosis_H37Rv MPPQPPLPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVG-LD
MUL_2809|M.ulcerans_Agy99 MPPEPPLPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGRLIVG-LD
MMAR_0061|M.marinum_M PADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLG---TPGVLTAG-TL
MAV_0059|M.avium_104 PENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLG---TPGVLTVG-TL
MSMEG_6595|M.smegmatis_MC2_155 AAGDAQAPGTASAIPDNTEVIAAIEADPALSAALPPAIAQSKTINLG-SN
MAB_4236c|M.abscessus_ATCC_199 GCAEGAAPGSSSFNLSPDQDRVRVAKVDAIAAEVPEGIRKRGTLVVTGDA
Mflv_3583|M.gilvum_PYR-GCK VPYAPNEFKD-PEGKLVGFDVDLMNAIAGTLG---LTPEYKEADFAKIIP
Mvan_2832|M.vanbaalenii_PYR-1 IPYAPNEFKD-ESGKIVGFDVDLMNAIAGTLG---LTPEYREADFAKIIP
TH_0053|M.thermoresistible__bu VPYKPNEFKN-AAGEIVGFDVDLMNAVARTLG---LAPEYRELPFEAILP
Mb0419c|M.bovis_AF2122/97 IGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERVT
Rv0411c|M.tuberculosis_H37Rv IGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERVT
MUL_2809|M.ulcerans_Agy99 IGSNLFSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRILSAAERIT
MMAR_0061|M.marinum_M SDAPPNTCIN-STGQFTGFDNELLRAIAAKLG---LQVRFVGTDFSGLLA
MAV_0059|M.avium_104 SGAPPNVCIT-PTGQYSGFDNQLLRAIAGKLG---LQVRFVGTDFAGLLA
MSMEG_6595|M.smegmatis_MC2_155 IQSAPNNFYAGDGKTPIGYEVDLAKAIAAKLG---VQAKHQDMAFGSLIT
MAB_4236c|M.abscessus_ATCC_199 NSSPPLRFYADDDKTMIGIETDIAYLVADILG---LRVDLRSADWAQNFV
* : :: :* : .
Mflv_3583|M.gilvum_PYR-GCK SIQGGTFDVGMSSFTDSKEREEQVDFVTYFSAG-TAWAQPAGGDIN--PE
Mvan_2832|M.vanbaalenii_PYR-1 SIQGGTFNVGMSSFTDSKEREQQVDFVTYFSAG-TLWAQPAGGQID--PE
TH_0053|M.thermoresistible__bu SVRAGDVHVGMASLTVTPERSAGADFVTYFQAG-TLWAQPAGGAVN--PA
Mb0419c|M.bovis_AF2122/97 ALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDSPITKVSD
Rv0411c|M.tuberculosis_H37Rv ALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRDSPITKVSD
MUL_2809|M.ulcerans_Agy99 ALQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRDSPIFKVSD
MMAR_0061|M.marinum_M QVAARRFDVGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPGSAITKFSD
MAV_0059|M.avium_104 QVASRRFDVGSSSIKATDERRQTVAFTNGYDFGYYALVVPPGSAIKEFTD
MSMEG_6595|M.smegmatis_MC2_155 SLQSGRVDMTMAAMNDTKERQQQIDFVDYFSSGITIMIQKGNPENITGPD
MAB_4236c|M.abscessus_ATCC_199 KVDSGEVDAFISNVTVTEERKEKFDFATYRLDNVTFEARRSLDWKVKGAR
: .. .. : * * .
Mflv_3583|M.gilvum_PYR-GCK DACGKKVAVQATTVQETDELPARSKKCVDEGKPAIEIIPFDSQDAATNAV
Mvan_2832|M.vanbaalenii_PYR-1 NACGKKVAVQATTVQETDELPARSKKCTDAGQPAIEIIAFDSQDAATNAV
TH_0053|M.thermoresistible__bu DACGLRVGVAYATIQESDEVPFKSEICTAAGKPPIDKVVYVSQDDLTEAL
Mb0419c|M.bovis_AF2122/97 LS-GKRVCVARGTTSLR---------RIREIAPPPVIVSVVNWADCLVAL
Rv0411c|M.tuberculosis_H37Rv LS-GKRVCVARGTTSLR---------RIREIAPPPVIVSVVNWADCLVAL
MUL_2809|M.ulcerans_Agy99 LS-GKRVCVARGTTSLR---------RIREIAPPPVIVSVVNWADCLVAL
MMAR_0061|M.marinum_M LAPGQRIGVVQGTVEES---------YVVNSLH-LQPVKYPDFATVYGNL
MAV_0059|M.avium_104 LAAGQRIGVVQGTVEES---------YVVDTLH-LQPVKYPDFATVYASL
MSMEG_6595|M.smegmatis_MC2_155 SLCGKNVAVVQGTSHQKFAAAQ-SQRCEQEGKPAVNVTATDSDTQNQNQL
MAB_4236c|M.abscessus_ATCC_199 DIAGKTIGVGSGTNQEALLVR-WNEENVAAGLPAADLKYFQQATGYYLAL
* : * * . :
Mflv_3583|M.gilvum_PYR-GCK VLGQADAMSADSPVTLYAIKQT---NGKLEQAGETFDSAPYGWPVEK-GS
Mvan_2832|M.vanbaalenii_PYR-1 VLGQADAMSADSPVTLYAIKQT---NGKLVQAGEVFDSAPYGWPVEK-GS
TH_0053|M.thermoresistible__bu MNGEIDAMSADSPVTGFAVKTS---GGALQEAGEIFSPAPYGWPVTR-GS
Mb0419c|M.bovis_AF2122/97 QQREIDAVSTDDTILAGLVEE----DPYLHIVGPDMADQPYGVGINLDNT
Rv0411c|M.tuberculosis_H37Rv QQREIDAVSTDDTILAGLVEE----DPYLHIVGPDMADQPYGVGINLDNT
MUL_2809|M.ulcerans_Agy99 QQREIDAVSTDDTILAGLVEE----DPYLHIVGPNMANQPYGIGINLDNT
MMAR_0061|M.marinum_M KTHQIDAWVAPGNQAEAAIRPG---DPAVLVANTFGAGDFVAYVVARDNR
MAV_0059|M.avium_104 KTRQIDAWVAPAGQAATTIQPG---DPAVVVANTISPGNFVAYAVAKDNK
MSMEG_6595|M.smegmatis_MC2_155 RTGRVAAILNDLPSAVYISRTAGDGNAFEVVPGPPIEGGPYGIGFNKDNV
MAB_4236c|M.abscessus_ATCC_199 ASGRIDAYVGPNPSAVFHSEATGQTKLVGTFSGAGEALQGEIAVLTKKDN
. * . . . .
Mflv_3583|M.gilvum_PYR-GCK PLAQSLLQALQHLIDNGKYQEIAANWGLEEGMIDKPVINGAIS-------
Mvan_2832|M.vanbaalenii_PYR-1 PLAQSLLQALEHLIETGKYKEIAANWGLEEGMIDKPVINGAVS-------
TH_0053|M.thermoresistible__bu PLAESLRQALEHLIATGEYRTIATMWGVEKGMIDRPEINAAAG-------
Mb0419c|M.bovis_AF2122/97 GLVRFVNGTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD-------
Rv0411c|M.tuberculosis_H37Rv GLVRFVNGTLERIRNDGTWNTLYRKWLTVLGPAPAPPTPRYVD-------
MUL_2809|M.ulcerans_Agy99 GLVRFVNGTLERIRNDGTWNTLYRKWLSVLGPAPAPPRPRYVD-------
MMAR_0061|M.marinum_M PLLDALNSGLDAVIADGTWSQLYSKWVPRTLPPGWKPGSRAVAAPTLPDF
MAV_0059|M.avium_104 PLVDALNSGLDAVIADGTWSNLYSQWVPRTLPPGWKPGSQAVAPPKLPDF
MSMEG_6595|M.smegmatis_MC2_155 ALRDAVAKALGELMTDGTYETILQSWGVEQGALKEPAINGGS--------
MAB_4236c|M.abscessus_ATCC_199 GLVRAYADAINHAIADGTYRKVLQRWGLEDEAVAKSEINPRGLPRQG---
* : * : : *
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M AAIAAAHRHKPVGPAAPKSALTQLRDSFFDWDMYRQAIPTLFKTGLPNTL
MAV_0059|M.avium_104 AAIAASQHHKAVGPAAPKSTLAQLRDSFFDWDMYRQAIPTLLRTGLPNTL
MSMEG_6595|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4236c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M ILTLSASIIGLALGMALAIAGISHQRWLRWPARVYTDIFRGLPEVVIILI
MAV_0059|M.avium_104 ILTFSASVIGLVLGMVLAVAGISHARWLRWPARVYTDVFRGLPEVVIILL
MSMEG_6595|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4236c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M IGLGVGPIVGGLTNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLE
MAV_0059|M.avium_104 IGLGIGPIVGGLTNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLE
MSMEG_6595|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4236c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M ASRALGFSYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLIA
MAV_0059|M.avium_104 ASRALGFSYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLVA
MSMEG_6595|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4236c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3583|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2832|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0053|M.thermoresistible__bu --------------------------------------------------
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0061|M.marinum_M QQRELFQVGRDLNAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDARLRRG
MAV_0059|M.avium_104 DQRELFQVGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLRRG
MSMEG_6595|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4236c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_3583|M.gilvum_PYR-GCK ----------------------
Mvan_2832|M.vanbaalenii_PYR-1 ----------------------
TH_0053|M.thermoresistible__bu ----------------------
Mb0419c|M.bovis_AF2122/97 ----------------------
Rv0411c|M.tuberculosis_H37Rv ----------------------
MUL_2809|M.ulcerans_Agy99 ----------------------
MMAR_0061|M.marinum_M RRRLDPEDPPGVVSSTIGEEMT
MAV_0059|M.avium_104 RAAVDPEEPAEMLT--FGQEIT
MSMEG_6595|M.smegmatis_MC2_155 ----------------------
MAB_4236c|M.abscessus_ATCC_199 ----------------------