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M. smegmatis MC2 155 MSMEG_3159 (-)

annotation: methylmalonyl-CoA mutase
coordinates: 3233834 - 3236089
length: 751

MTATTGSEIRSFADVPLEGETPAAAATPEARDAQVSAAASAHGYAPDQLTWTTPEGIDVKPVYIAADRDE
AVEAGYPLDSFPGAPPFIRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLATHR
GYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGAVLPILALYVVAAEEQGVPPEKLA
GTIQNDILKEFMVRNTYIYPPKESMRIISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADG
VEYIKAGLDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSEFEPKSEKSLSLRTHSQTSG
WSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLLLQQESGTTRPIDPW
GGSYYVEWLTHQLAERARAHIKEVAEHGGMAQAISEGIPKLRIEEAAARTQARIDSGAQPVIGVNKYQVD
EDTEIEVLKVENSRVRAEQIAKLQQLRAERDEAATQAALDELTRAAAASGPAGEDGLGNNLLALAIDAAR
AKATVGEISDALEKVYGRHQAEIRTISGVYRDEVGKGSNIASATELVNKFAEADGRRPRILVAKMGQDGH
DRGQKVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTLVPALRDALAEVGRPDI
MIVVGGVIPPGDFDELYAAGATAIFPPGTVIADAAIGLLHKLAERLGYELS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3159--100% (751)methylmalonyl-CoA mutase
M. smegmatis MC2 155MSMEG_4881-e-11043.45% (534) methylmalonyl-CoA mutase, N-terminus of large subunit
M. smegmatis MC2 155MSMEG_3158mutA2e-2929.27% (451) methylmalonyl-CoA mutase, small subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1530mutB0.089.89% (742) methylmalonyl-CoA mutase
M. gilvum PYR-GCKMflv_3649-0.091.66% (743) methylmalonyl-CoA mutase
M. tuberculosis H37RvRv1493mutB0.089.89% (742) methylmalonyl-CoA mutase
M. leprae Br4923MLBr_01799mutB0.086.86% (746) methylmalonyl-CoA mutase
M. abscessus ATCC 19977MAB_2711c-0.087.07% (750) methylmalonyl-CoA mutase
M. marinum MMMAR_2303mutB0.090.40% (750) methylmalonyl-CoA mutase large subunit, MutB
M. avium 104MAV_3277-0.089.69% (747) methylmalonyl-CoA mutase
M. thermoresistible (build 8)TH_0613mutB0.093.77% (690) PROBABLE METHYLMALONYL-CoA MUTASE LARGE SUBUNIT MUTB (MCM)
M. ulcerans Agy99MUL_1506mutB0.089.87% (750) methylmalonyl-CoA mutase
M. vanbaalenii PYR-1Mvan_2763-0.091.21% (751) methylmalonyl-CoA mutase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3649|M.gilvum_PYR-GCK          ----MTVTERRKS--------IDSFAEVPLLGDGAAAAPTQAEAAEQVTA
Mvan_2763|M.vanbaalenii_PYR-1       ----MTAIEPVK---------IDSFGDVPLHGDTAAAAPTYSDVTTQVSA
MSMEG_3159|M.smegmatis_MC2_155      ----MTATTGSE---------IRSFADVPLEGETPAAAATPEARDAQVSA
MAB_2711c|M.abscessus_ATCC_199      MTDLTDLSESGTI--------LGSFADVPLHGDRVSVAPDTAAVQTAVSE
TH_0613|M.thermoresistible__bu      --------------------------------------------------
Mb1530|M.bovis_AF2122/97            ----MTTKTP----------VIGSFAGVPLHSERAAQSPTEAAVHTHVAA
Rv1493|M.tuberculosis_H37Rv         ----MTTKTP----------VIGSFAGVPLHSERAAQSPTEAAVHTHVAA
MLBr_01799|M.leprae_Br4923          ----MTVRDVGGQQDRETTFVVGSFADIPLRSDRVVWPPSEAAVEKHVFS
MAV_3277|M.avium_104                ----MTTTAP----------AVGSFADVPLRSERPVAPATEAAVEEHVAA
MMAR_2303|M.marinum_M               ----MTTTAS----------AIGSFADVPLHGERAVASATEAAVEKQVAA
MUL_1506|M.ulcerans_Agy99           ----MTTTAS----------AIGSFADVPLHGERAVASATEASVEKQVAA
                                                                                      

Mflv_3649|M.gilvum_PYR-GCK          AAAAHGYAADQSDWTTPEGIDVKPVFVAADRDDVVGAGYPLDSLPGEPPF
Mvan_2763|M.vanbaalenii_PYR-1       AAAAHGYTADQLDWATPEGIDVKPVYIGADRDAIVAAGYPLDSLPGEPPF
MSMEG_3159|M.smegmatis_MC2_155      AASAHGYAPDQLTWTTPEGIDVKPVYIAADRDEAVEAGYPLDSFPGAPPF
MAB_2711c|M.abscessus_ATCC_199      AAAAHGYSPEQLDWETPEAITVKPIYTAADREAVRAQGYPLDTFPGQVPF
TH_0613|M.thermoresistible__bu      ------------------------VYIGADRAAAEAAGYPLHTFPGAVPY
Mb1530|M.bovis_AF2122/97            AAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPF
Rv1493|M.tuberculosis_H37Rv         AAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPF
MLBr_01799|M.leprae_Br4923          AASAHGYTVDQLHWHTPEGIDVKPVYIAADRAAAEAGGYPLHSFPGEPPY
MAV_3277|M.avium_104                IAAAHLYTPDQLHWHTPEDIAVKPVYIGADRAAVEADGYPLHTFPGEPPF
MMAR_2303|M.marinum_M               TAAAHGYATDQLRWQTPEGIEVKPVYIGADRRAAQADGYPVNSFPGEPPY
MUL_1506|M.ulcerans_Agy99           TAAAHGYATDQLRWQTPEGIEVKPVYIGADRRAAQADGYPVNSFPGEPPY
                                                            :: .***      ***:.::**  *:

Mflv_3649|M.gilvum_PYR-GCK          VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
Mvan_2763|M.vanbaalenii_PYR-1       VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
MSMEG_3159|M.smegmatis_MC2_155      IRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
MAB_2711c|M.abscessus_ATCC_199      LRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
TH_0613|M.thermoresistible__bu      IRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
Mb1530|M.bovis_AF2122/97            VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
Rv1493|M.tuberculosis_H37Rv         VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
MLBr_01799|M.leprae_Br4923          LRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
MAV_3277|M.avium_104                VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
MMAR_2303|M.marinum_M               VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
MUL_1506|M.ulcerans_Agy99           VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
                                    :*************************:***********************

Mflv_3649|M.gilvum_PYR-GCK          THRGYDSDHPRVAGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
Mvan_2763|M.vanbaalenii_PYR-1       THRGYDSDHPRVAGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
MSMEG_3159|M.smegmatis_MC2_155      THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
MAB_2711c|M.abscessus_ATCC_199      THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLGSVSVSMTMNGA
TH_0613|M.thermoresistible__bu      THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLGSVSVSMTMNGA
Mb1530|M.bovis_AF2122/97            THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
Rv1493|M.tuberculosis_H37Rv         THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
MLBr_01799|M.leprae_Br4923          THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSAVSVSMTMNGA
MAV_3277|M.avium_104                THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
MMAR_2303|M.marinum_M               THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
MUL_1506|M.ulcerans_Agy99           THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
                                    ************ *************************.:**********

Mflv_3649|M.gilvum_PYR-GCK          VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
Mvan_2763|M.vanbaalenii_PYR-1       VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MSMEG_3159|M.smegmatis_MC2_155      VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKESMRI
MAB_2711c|M.abscessus_ATCC_199      VLPILALYVVAAEEQGVGTEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
TH_0613|M.thermoresistible__bu      VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
Mb1530|M.bovis_AF2122/97            VLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRI
Rv1493|M.tuberculosis_H37Rv         VLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MLBr_01799|M.leprae_Br4923          VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPEPSMRI
MAV_3277|M.avium_104                VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MMAR_2303|M.marinum_M               VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MUL_1506|M.ulcerans_Agy99           VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
                                    ***************** .*:***********************: ****

Mflv_3649|M.gilvum_PYR-GCK          ISDIFGYTSAKMPKFNSISISGYHIQEAGATADLELGYTLADGVEYIKAG
Mvan_2763|M.vanbaalenii_PYR-1       ISDIFGYTSAKMPKFNSISISGYHIQEAGATADLELGYTLADGVEYIKAG
MSMEG_3159|M.smegmatis_MC2_155      ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG
MAB_2711c|M.abscessus_ATCC_199      ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG
TH_0613|M.thermoresistible__bu      ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG
Mb1530|M.bovis_AF2122/97            ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAG
Rv1493|M.tuberculosis_H37Rv         ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAG
MLBr_01799|M.leprae_Br4923          ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
MAV_3277|M.avium_104                ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
MMAR_2303|M.marinum_M               ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
MUL_1506|M.ulcerans_Agy99           ISDIFAYTSVKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
                                    *****.***.**************************.*******:**:**

Mflv_3649|M.gilvum_PYR-GCK          LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAEFDPKSS
Mvan_2763|M.vanbaalenii_PYR-1       LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSQFEPKSA
MSMEG_3159|M.smegmatis_MC2_155      LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSEFEPKSE
MAB_2711c|M.abscessus_ATCC_199      LAGGLDIDVFAPRLSFFWAIGMNFFMEVAKLRAGRLLWSELVAQFDPKSS
TH_0613|M.thermoresistible__bu      LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFDPKNS
Mb1530|M.bovis_AF2122/97            LNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSA
Rv1493|M.tuberculosis_H37Rv         LNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSA
MLBr_01799|M.leprae_Br4923          LDAGLDIDTFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFGPQSP
MAV_3277|M.avium_104                LDAELDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSQFNPKNP
MMAR_2303|M.marinum_M               LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFEPKNS
MUL_1506|M.ulcerans_Agy99           LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFEPKNS
                                    * . **** *********.***********************::* *:. 

Mflv_3649|M.gilvum_PYR-GCK          KSLSLRTHSQTSGWSLTAQDAFNNVARTCIEAMAATQGHTQSLHTNALDE
Mvan_2763|M.vanbaalenii_PYR-1       KSLSLRTHSQTSGWSLTAQDAFNNVARTCVEAMAATQGHTQSLHTNALDE
MSMEG_3159|M.smegmatis_MC2_155      KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
MAB_2711c|M.abscessus_ATCC_199      KSQSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
TH_0613|M.thermoresistible__bu      KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
Mb1530|M.bovis_AF2122/97            KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
Rv1493|M.tuberculosis_H37Rv         KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
MLBr_01799|M.leprae_Br4923          KSLSLRTHSQTSGWSLTAQDPFNNVARTCIEAMAATQGHTQSLHTNALDE
MAV_3277|M.avium_104                KSLSLRTHSQTSGWSLTAQDAFNNVARTCIEAMAATQGHTQSLHTNALDE
MMAR_2303|M.marinum_M               KSRSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
MUL_1506|M.ulcerans_Agy99           KSRSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
                                    ** ***************** ********:********************

Mflv_3649|M.gilvum_PYR-GCK          ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTYQLAEKA
Mvan_2763|M.vanbaalenii_PYR-1       ALALPTDFSARIARNTQLLLQQESGTTRPIDPWAGSYYVESLTYQLAEKA
MSMEG_3159|M.smegmatis_MC2_155      ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAERA
MAB_2711c|M.abscessus_ATCC_199      ALALPTDFSARIARNTQLLIQQESGTCRPIDPWGGSYYVEWLTHQLASRA
TH_0613|M.thermoresistible__bu      ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAERA
Mb1530|M.bovis_AF2122/97            ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRA
Rv1493|M.tuberculosis_H37Rv         ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRA
MLBr_01799|M.leprae_Br4923          ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHQLAARA
MAV_3277|M.avium_104                ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHHLARKA
MMAR_2303|M.marinum_M               ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAQRA
MUL_1506|M.ulcerans_Agy99           ALALPTDFSARIARNTQLLLQQESGTTRPIDPWAGSYYVEWLTHQLAQRA
                                    ******************::****** ******.****** **::** :*

Mflv_3649|M.gilvum_PYR-GCK          RGHIREIAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVIGVNKY
Mvan_2763|M.vanbaalenii_PYR-1       RAHIAEIAEYGGMAQAIDAGIPKLRIEEAAARTQARIDSGQQTVIGVNRY
MSMEG_3159|M.smegmatis_MC2_155      RAHIKEVAEHGGMAQAISEGIPKLRIEEAAARTQARIDSGAQPVIGVNKY
MAB_2711c|M.abscessus_ATCC_199      REHIREVTEAGGMAQAIDQGIPKLRIEEAAARTQARIDSGRQPVIGVNKY
TH_0613|M.thermoresistible__bu      RAHIREVDEHGGMAQAISDGVPKLRIEEAAARTQARIDSGAQPVIGVNKY
Mb1530|M.bovis_AF2122/97            RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKY
Rv1493|M.tuberculosis_H37Rv         RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKY
MLBr_01799|M.leprae_Br4923          RTHIAEVAEHGGMAAAISDGIPKLRIEEAAARTQARIDSGRQPVVGVNKY
MAV_3277|M.avium_104                RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGIQPVIGVNKY
MMAR_2303|M.marinum_M               RAHINEVAELGGMAAAISEGIPKLRIEEAAARTQARIDSGQQPVIGVNKY
MUL_1506|M.ulcerans_Agy99           RAHINEVAELGGMAAAIGEGIPKLRIEEAAARTQARIDSGQQPVIGVNKY
                                    * ** *: * **** **. *:******************* *.*:***:*

Mflv_3649|M.gilvum_PYR-GCK          QVDEDHEIEVLKVENSRVRAEQLAKLERLRRERDETATQAALAELTRAAA
Mvan_2763|M.vanbaalenii_PYR-1       QVDEDHEIEVLKVENSRVRAEQIAKLERLRSERDDAATQAALAELTRAAA
MSMEG_3159|M.smegmatis_MC2_155      QVDEDTEIEVLKVENSRVRAEQIAKLQQLRAERDEAATQAALDELTRAAA
MAB_2711c|M.abscessus_ATCC_199      QVAEDQQIEVLKVENSRVRAEQLAKLQQLRAERDDDAVQAALAELTRAAA
TH_0613|M.thermoresistible__bu      QVDEDHEIEVLKVDNSRVRAEQLAKLEQLRAERDQAAVDAALDELSRAAA
Mb1530|M.bovis_AF2122/97            QVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAA
Rv1493|M.tuberculosis_H37Rv         QVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAA
MLBr_01799|M.leprae_Br4923          QVDQDHEIEVLKVENSRVRAEQVAKLQQLRANRDQLAVDAALAELSGAAG
MAV_3277|M.avium_104                QVEEDQEVEVLKVENSRVRAEQLAKLKELRDSRDQSAVDAALAELSRAAA
MMAR_2303|M.marinum_M               QVDEDQQIEVLKVENSRVRAEQLAKLQELRAGRDQAAVDAALAELTRAAA
MUL_1506|M.ulcerans_Agy99           QVDEDQQIEVLKVENSRVRAEQLAKLQELRAGRDQAAVDAALAELTRAAA
                                    ** :* ::*****:********:***:.**  **: *. *** **: **.

Mflv_3649|M.gilvum_PYR-GCK          ASGVAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIA
Mvan_2763|M.vanbaalenii_PYR-1       ASGAAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIA
MSMEG_3159|M.smegmatis_MC2_155      ASGPAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIS
MAB_2711c|M.abscessus_ATCC_199      DSGRAGEDGLGNNLMALAINAARHKATVGEISDALEKVYGRHQAEIRTIS
TH_0613|M.thermoresistible__bu      ATGPAGADGLGNNLMALAINAARAKATVGEISSALERVWGRHQAEIRTIS
Mb1530|M.bovis_AF2122/97            EQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTIS
Rv1493|M.tuberculosis_H37Rv         EQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTIS
MLBr_01799|M.leprae_Br4923          AHGRAG-----DNLLALAINAARVQATVGEISDALERVYGRHQAKIRTIT
MAV_3277|M.avium_104                AQGRAGEDGLGNNLLALAINAARAKATVGEISDALEKVYGRHQAEIRTIA
MMAR_2303|M.marinum_M               AHGRAGDDGLGNNLLALAIDAARAKATVGEISDALEQVYGRHQAEIRTIA
MUL_1506|M.ulcerans_Agy99           AHGRAGDDGLGNNLLALAIDAARAKATVGEISDALEQVYGRHQAEIRTIA
                                      * **     :**:****:*** :*******.***:*:***:*:****:

Mflv_3649|M.gilvum_PYR-GCK          GVYRDEVG---MASNVSGATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
Mvan_2763|M.vanbaalenii_PYR-1       GVYRDEVG---MAGNVSSATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
MSMEG_3159|M.smegmatis_MC2_155      GVYRDEVG---KGSNIASATELVNKFAEADGRRPRILVAKMGQDGHDRGQ
MAB_2711c|M.abscessus_ATCC_199      GVYRDEVGRDGAVSSVTQATELVQKFADADGRRPRVLVAKMGQDGHDRGQ
TH_0613|M.thermoresistible__bu      GVYRDEVG---KASNIASATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
Mb1530|M.bovis_AF2122/97            GVYR---DEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQ
Rv1493|M.tuberculosis_H37Rv         GVYR---DEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQ
MLBr_01799|M.leprae_Br4923          GVYRREVGEAGKATDIANATELVKKFAEADGRRPRILVAKMGQDGHDRGQ
MAV_3277|M.avium_104                GVYR---DEAGKATNIATATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
MMAR_2303|M.marinum_M               GVYRDEVQGGGNITPLSKATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
MUL_1506|M.ulcerans_Agy99           GVYRDEVQGGGNITPLSKATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
                                    ****           :: *****:***:*******:*:************

Mflv_3649|M.gilvum_PYR-GCK          KVIATAFADIGFDVDVGSLFSTPDEVARQAADNDVHVVGVSSLAAGHLTL
Mvan_2763|M.vanbaalenii_PYR-1       KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL
MSMEG_3159|M.smegmatis_MC2_155      KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL
MAB_2711c|M.abscessus_ATCC_199      KVIATAFADIGFDVDVGPLFQTPEEVARQAADNDVHVVGVSSLAAGHLTL
TH_0613|M.thermoresistible__bu      KVIATAFADIGFDVDVGSLFSTPDEVARQAADNDVHVVGVSSLAAGHLTL
Mb1530|M.bovis_AF2122/97            KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL
Rv1493|M.tuberculosis_H37Rv         KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL
MLBr_01799|M.leprae_Br4923          KVVATAFADLGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL
MAV_3277|M.avium_104                KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL
MMAR_2303|M.marinum_M               KVIATAFADIGFDVDVGSLFSTPEEVAREAADNDVHVVGVSSLAAGHLTL
MUL_1506|M.ulcerans_Agy99           KVIATAFADIGFDVDVGSLFSTPEEVAREAADNDVHVVGVSSLAAGHLTL
                                    **:******:*******.**.**:****:********:************

Mflv_3649|M.gilvum_PYR-GCK          VPALRDALAEVGRPDIMVVVGGVIPPGDFDELYEAGATAIFPPGTVIADA
Mvan_2763|M.vanbaalenii_PYR-1       VPALRDALAEVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
MSMEG_3159|M.smegmatis_MC2_155      VPALRDALAEVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
MAB_2711c|M.abscessus_ATCC_199      VPALRQALAEVGRPDIMIVVGGVIPPGDFDELYQAGAAAIFPPGTVISEA
TH_0613|M.thermoresistible__bu      VPALRDALAEVGRPDIMIVVGGVIPPGDFEELYRAGATAIYPPGTVIADA
Mb1530|M.bovis_AF2122/97            VPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
Rv1493|M.tuberculosis_H37Rv         VPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
MLBr_01799|M.leprae_Br4923          VPALRDALADVGRPDIMIVVGGVIPPDDFDELYAAGATAIFPPGTVIAYA
MAV_3277|M.avium_104                VPALRDALKEVGRPDIMIVVGGVIPPGDFDELYAAGAAAIFPPGTVIADA
MMAR_2303|M.marinum_M               VPALRDALAKVGRPDIMIVVGGVIPPGDFDELYAAGATAIYPPGTVIADA
MUL_1506|M.ulcerans_Agy99           VPALRDALAKVGRPDIMIVVGGVIPPGDFDELYAAGATAIYPPGTVIADA
                                    *****:** .*******:********.**:*** ***:**:******: *

Mflv_3649|M.gilvum_PYR-GCK          AIGLLNKLAERLGYSLS
Mvan_2763|M.vanbaalenii_PYR-1       AIGLLNKLAERLGYTLS
MSMEG_3159|M.smegmatis_MC2_155      AIGLLHKLAERLGYELS
MAB_2711c|M.abscessus_ATCC_199      AIGLLHKLAERLGYDLT
TH_0613|M.thermoresistible__bu      AIGLLHKLAERLGYDLS
Mb1530|M.bovis_AF2122/97            AIDLLHRLAERLGYTLD
Rv1493|M.tuberculosis_H37Rv         AIDLLHRLAERLGYTLD
MLBr_01799|M.leprae_Br4923          AIGLLHKLAGRLGYTLT
MAV_3277|M.avium_104                AIGLLHKLAERLGYDLG
MMAR_2303|M.marinum_M               AIGLLHKLAERLGYPLD
MUL_1506|M.ulcerans_Agy99           AIGLLHKLAERLGYPLD
                                    **.**::** **** *