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MTAIEPVKIDSFGDVPLHGDTAAAAPTYSDVTTQVSAAAAAHGYTADQLDWATPEGIDVKPVYIGADRDA IVAAGYPLDSLPGEPPFVRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLATHR GYDSDHPRVAGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGAVLPILALYVVAAEEQGVPPEKLA GTIQNDILKEFMVRNTYIYPPKPSMRIISDIFGYTSAKMPKFNSISISGYHIQEAGATADLELGYTLADG VEYIKAGLDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSQFEPKSAKSLSLRTHSQTSG WSLTAQDAFNNVARTCVEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLLLQQESGTTRPIDPW AGSYYVESLTYQLAEKARAHIAEIAEYGGMAQAIDAGIPKLRIEEAAARTQARIDSGQQTVIGVNRYQVD EDHEIEVLKVENSRVRAEQIAKLERLRSERDDAATQAALAELTRAAAASGAAGEDGLGNNLLALAIDAAR AKATVGEISDALEKVYGRHQAEIRTIAGVYRDEVGMAGNVSSATELVEKFAEADGRRPRILVAKMGQDGH DRGQKVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTLVPALRDALAEVGRPDI MIVVGGVIPPGDFDELYAAGATAIFPPGTVIADAAIGLLNKLAERLGYTLS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2763 | - | - | 100% (751) | methylmalonyl-CoA mutase |
M. vanbaalenii PYR-1 | Mvan_4261 | - | e-113 | 43.90% (533) | methylmalonyl-CoA mutase, large subunit |
M. vanbaalenii PYR-1 | Mvan_2762 | - | 2e-34 | 30.68% (453) | methylmalonyl-CoA mutase, beta subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1530 | mutB | 0.0 | 88.40% (750) | methylmalonyl-CoA mutase |
M. gilvum PYR-GCK | Mflv_3649 | - | 0.0 | 93.35% (752) | methylmalonyl-CoA mutase |
M. tuberculosis H37Rv | Rv1493 | mutB | 0.0 | 88.40% (750) | methylmalonyl-CoA mutase |
M. leprae Br4923 | MLBr_01799 | mutB | 0.0 | 85.25% (746) | methylmalonyl-CoA mutase |
M. abscessus ATCC 19977 | MAB_2711c | - | 0.0 | 86.86% (746) | methylmalonyl-CoA mutase |
M. marinum M | MMAR_2303 | mutB | 0.0 | 89.40% (745) | methylmalonyl-CoA mutase large subunit, MutB |
M. avium 104 | MAV_3277 | - | 0.0 | 88.53% (750) | methylmalonyl-CoA mutase |
M. smegmatis MC2 155 | MSMEG_3159 | - | 0.0 | 91.21% (751) | methylmalonyl-CoA mutase |
M. thermoresistible (build 8) | TH_0613 | mutB | 0.0 | 91.01% (690) | PROBABLE METHYLMALONYL-CoA MUTASE LARGE SUBUNIT MUTB (MCM) |
M. ulcerans Agy99 | MUL_1506 | mutB | 0.0 | 89.40% (745) | methylmalonyl-CoA mutase |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_2763|M.vanbaalenii_PYR-1 ----MTAIEPVK---------IDSFGDVPLHGDTAAAAPTYSDVTTQVSA Mflv_3649|M.gilvum_PYR-GCK ----MTVTERRKS--------IDSFAEVPLLGDGAAAAPTQAEAAEQVTA MSMEG_3159|M.smegmatis_MC2_155 ----MTATTGSE---------IRSFADVPLEGETPAAAATPEARDAQVSA MAB_2711c|M.abscessus_ATCC_199 MTDLTDLSESGTI--------LGSFADVPLHGDRVSVAPDTAAVQTAVSE TH_0613|M.thermoresistible__bu -------------------------------------------------- Mb1530|M.bovis_AF2122/97 ----MTTKTP----------VIGSFAGVPLHSERAAQSPTEAAVHTHVAA Rv1493|M.tuberculosis_H37Rv ----MTTKTP----------VIGSFAGVPLHSERAAQSPTEAAVHTHVAA MLBr_01799|M.leprae_Br4923 ----MTVRDVGGQQDRETTFVVGSFADIPLRSDRVVWPPSEAAVEKHVFS MAV_3277|M.avium_104 ----MTTTAP----------AVGSFADVPLRSERPVAPATEAAVEEHVAA MMAR_2303|M.marinum_M ----MTTTAS----------AIGSFADVPLHGERAVASATEAAVEKQVAA MUL_1506|M.ulcerans_Agy99 ----MTTTAS----------AIGSFADVPLHGERAVASATEASVEKQVAA Mvan_2763|M.vanbaalenii_PYR-1 AAAAHGYTADQLDWATPEGIDVKPVYIGADRDAIVAAGYPLDSLPGEPPF Mflv_3649|M.gilvum_PYR-GCK AAAAHGYAADQSDWTTPEGIDVKPVFVAADRDDVVGAGYPLDSLPGEPPF MSMEG_3159|M.smegmatis_MC2_155 AASAHGYAPDQLTWTTPEGIDVKPVYIAADRDEAVEAGYPLDSFPGAPPF MAB_2711c|M.abscessus_ATCC_199 AAAAHGYSPEQLDWETPEAITVKPIYTAADREAVRAQGYPLDTFPGQVPF TH_0613|M.thermoresistible__bu ------------------------VYIGADRAAAEAAGYPLHTFPGAVPY Mb1530|M.bovis_AF2122/97 AAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPF Rv1493|M.tuberculosis_H37Rv AAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPF MLBr_01799|M.leprae_Br4923 AASAHGYTVDQLHWHTPEGIDVKPVYIAADRAAAEAGGYPLHSFPGEPPY MAV_3277|M.avium_104 IAAAHLYTPDQLHWHTPEDIAVKPVYIGADRAAVEADGYPLHTFPGEPPF MMAR_2303|M.marinum_M TAAAHGYATDQLRWQTPEGIEVKPVYIGADRRAAQADGYPVNSFPGEPPY MUL_1506|M.ulcerans_Agy99 TAAAHGYATDQLRWQTPEGIEVKPVYIGADRRAAQADGYPVNSFPGEPPY :: .*** ***:.::** *: Mvan_2763|M.vanbaalenii_PYR-1 VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA Mflv_3649|M.gilvum_PYR-GCK VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA MSMEG_3159|M.smegmatis_MC2_155 IRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA MAB_2711c|M.abscessus_ATCC_199 LRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA TH_0613|M.thermoresistible__bu IRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA Mb1530|M.bovis_AF2122/97 VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA Rv1493|M.tuberculosis_H37Rv VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA MLBr_01799|M.leprae_Br4923 LRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA MAV_3277|M.avium_104 VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA MMAR_2303|M.marinum_M VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA MUL_1506|M.ulcerans_Agy99 VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA :*************************:*********************** Mvan_2763|M.vanbaalenii_PYR-1 THRGYDSDHPRVAGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA Mflv_3649|M.gilvum_PYR-GCK THRGYDSDHPRVAGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA MSMEG_3159|M.smegmatis_MC2_155 THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA MAB_2711c|M.abscessus_ATCC_199 THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLGSVSVSMTMNGA TH_0613|M.thermoresistible__bu THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLGSVSVSMTMNGA Mb1530|M.bovis_AF2122/97 THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA Rv1493|M.tuberculosis_H37Rv THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA MLBr_01799|M.leprae_Br4923 THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSAVSVSMTMNGA MAV_3277|M.avium_104 THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA MMAR_2303|M.marinum_M THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA MUL_1506|M.ulcerans_Agy99 THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA ************ *************************.:********** Mvan_2763|M.vanbaalenii_PYR-1 VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI Mflv_3649|M.gilvum_PYR-GCK VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI MSMEG_3159|M.smegmatis_MC2_155 VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKESMRI MAB_2711c|M.abscessus_ATCC_199 VLPILALYVVAAEEQGVGTEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI TH_0613|M.thermoresistible__bu VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI Mb1530|M.bovis_AF2122/97 VLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRI Rv1493|M.tuberculosis_H37Rv VLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRI MLBr_01799|M.leprae_Br4923 VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPEPSMRI MAV_3277|M.avium_104 VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI MMAR_2303|M.marinum_M VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI MUL_1506|M.ulcerans_Agy99 VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI ***************** .*:***********************: **** Mvan_2763|M.vanbaalenii_PYR-1 ISDIFGYTSAKMPKFNSISISGYHIQEAGATADLELGYTLADGVEYIKAG Mflv_3649|M.gilvum_PYR-GCK ISDIFGYTSAKMPKFNSISISGYHIQEAGATADLELGYTLADGVEYIKAG MSMEG_3159|M.smegmatis_MC2_155 ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG MAB_2711c|M.abscessus_ATCC_199 ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG TH_0613|M.thermoresistible__bu ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG Mb1530|M.bovis_AF2122/97 ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAG Rv1493|M.tuberculosis_H37Rv ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAG MLBr_01799|M.leprae_Br4923 ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG MAV_3277|M.avium_104 ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG MMAR_2303|M.marinum_M ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG MUL_1506|M.ulcerans_Agy99 ISDIFAYTSVKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG *****.***.**************************.*******:**:** Mvan_2763|M.vanbaalenii_PYR-1 LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSQFEPKSA Mflv_3649|M.gilvum_PYR-GCK LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAEFDPKSS MSMEG_3159|M.smegmatis_MC2_155 LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSEFEPKSE MAB_2711c|M.abscessus_ATCC_199 LAGGLDIDVFAPRLSFFWAIGMNFFMEVAKLRAGRLLWSELVAQFDPKSS TH_0613|M.thermoresistible__bu LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFDPKNS Mb1530|M.bovis_AF2122/97 LNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSA Rv1493|M.tuberculosis_H37Rv LNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSA MLBr_01799|M.leprae_Br4923 LDAGLDIDTFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFGPQSP MAV_3277|M.avium_104 LDAELDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSQFNPKNP MMAR_2303|M.marinum_M LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFEPKNS MUL_1506|M.ulcerans_Agy99 LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFEPKNS * . **** *********.***********************::* *:. Mvan_2763|M.vanbaalenii_PYR-1 KSLSLRTHSQTSGWSLTAQDAFNNVARTCVEAMAATQGHTQSLHTNALDE Mflv_3649|M.gilvum_PYR-GCK KSLSLRTHSQTSGWSLTAQDAFNNVARTCIEAMAATQGHTQSLHTNALDE MSMEG_3159|M.smegmatis_MC2_155 KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE MAB_2711c|M.abscessus_ATCC_199 KSQSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE TH_0613|M.thermoresistible__bu KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE Mb1530|M.bovis_AF2122/97 KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE Rv1493|M.tuberculosis_H37Rv KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE MLBr_01799|M.leprae_Br4923 KSLSLRTHSQTSGWSLTAQDPFNNVARTCIEAMAATQGHTQSLHTNALDE MAV_3277|M.avium_104 KSLSLRTHSQTSGWSLTAQDAFNNVARTCIEAMAATQGHTQSLHTNALDE MMAR_2303|M.marinum_M KSRSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE MUL_1506|M.ulcerans_Agy99 KSRSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE ** ***************** ********:******************** Mvan_2763|M.vanbaalenii_PYR-1 ALALPTDFSARIARNTQLLLQQESGTTRPIDPWAGSYYVESLTYQLAEKA Mflv_3649|M.gilvum_PYR-GCK ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTYQLAEKA MSMEG_3159|M.smegmatis_MC2_155 ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAERA MAB_2711c|M.abscessus_ATCC_199 ALALPTDFSARIARNTQLLIQQESGTCRPIDPWGGSYYVEWLTHQLASRA TH_0613|M.thermoresistible__bu ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAERA Mb1530|M.bovis_AF2122/97 ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRA Rv1493|M.tuberculosis_H37Rv ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRA MLBr_01799|M.leprae_Br4923 ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHQLAARA MAV_3277|M.avium_104 ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHHLARKA MMAR_2303|M.marinum_M ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAQRA MUL_1506|M.ulcerans_Agy99 ALALPTDFSARIARNTQLLLQQESGTTRPIDPWAGSYYVEWLTHQLAQRA ******************::****** ******.****** **::** :* Mvan_2763|M.vanbaalenii_PYR-1 RAHIAEIAEYGGMAQAIDAGIPKLRIEEAAARTQARIDSGQQTVIGVNRY Mflv_3649|M.gilvum_PYR-GCK RGHIREIAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVIGVNKY MSMEG_3159|M.smegmatis_MC2_155 RAHIKEVAEHGGMAQAISEGIPKLRIEEAAARTQARIDSGAQPVIGVNKY MAB_2711c|M.abscessus_ATCC_199 REHIREVTEAGGMAQAIDQGIPKLRIEEAAARTQARIDSGRQPVIGVNKY TH_0613|M.thermoresistible__bu RAHIREVDEHGGMAQAISDGVPKLRIEEAAARTQARIDSGAQPVIGVNKY Mb1530|M.bovis_AF2122/97 RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKY Rv1493|M.tuberculosis_H37Rv RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKY MLBr_01799|M.leprae_Br4923 RTHIAEVAEHGGMAAAISDGIPKLRIEEAAARTQARIDSGRQPVVGVNKY MAV_3277|M.avium_104 RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGIQPVIGVNKY MMAR_2303|M.marinum_M RAHINEVAELGGMAAAISEGIPKLRIEEAAARTQARIDSGQQPVIGVNKY MUL_1506|M.ulcerans_Agy99 RAHINEVAELGGMAAAIGEGIPKLRIEEAAARTQARIDSGQQPVIGVNKY * ** *: * **** **. *:******************* *.*:***:* Mvan_2763|M.vanbaalenii_PYR-1 QVDEDHEIEVLKVENSRVRAEQIAKLERLRSERDDAATQAALAELTRAAA Mflv_3649|M.gilvum_PYR-GCK QVDEDHEIEVLKVENSRVRAEQLAKLERLRRERDETATQAALAELTRAAA MSMEG_3159|M.smegmatis_MC2_155 QVDEDTEIEVLKVENSRVRAEQIAKLQQLRAERDEAATQAALDELTRAAA MAB_2711c|M.abscessus_ATCC_199 QVAEDQQIEVLKVENSRVRAEQLAKLQQLRAERDDDAVQAALAELTRAAA TH_0613|M.thermoresistible__bu QVDEDHEIEVLKVDNSRVRAEQLAKLEQLRAERDQAAVDAALDELSRAAA Mb1530|M.bovis_AF2122/97 QVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAA Rv1493|M.tuberculosis_H37Rv QVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAA MLBr_01799|M.leprae_Br4923 QVDQDHEIEVLKVENSRVRAEQVAKLQQLRANRDQLAVDAALAELSGAAG MAV_3277|M.avium_104 QVEEDQEVEVLKVENSRVRAEQLAKLKELRDSRDQSAVDAALAELSRAAA MMAR_2303|M.marinum_M QVDEDQQIEVLKVENSRVRAEQLAKLQELRAGRDQAAVDAALAELTRAAA MUL_1506|M.ulcerans_Agy99 QVDEDQQIEVLKVENSRVRAEQLAKLQELRAGRDQAAVDAALAELTRAAA ** :* ::*****:********:***:.** **: *. *** **: **. Mvan_2763|M.vanbaalenii_PYR-1 ASGAAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIA Mflv_3649|M.gilvum_PYR-GCK ASGVAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIA MSMEG_3159|M.smegmatis_MC2_155 ASGPAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIS MAB_2711c|M.abscessus_ATCC_199 DSGRAGEDGLGNNLMALAINAARHKATVGEISDALEKVYGRHQAEIRTIS TH_0613|M.thermoresistible__bu ATGPAGADGLGNNLMALAINAARAKATVGEISSALERVWGRHQAEIRTIS Mb1530|M.bovis_AF2122/97 EQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTIS Rv1493|M.tuberculosis_H37Rv EQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTIS MLBr_01799|M.leprae_Br4923 AHGRAG-----DNLLALAINAARVQATVGEISDALERVYGRHQAKIRTIT MAV_3277|M.avium_104 AQGRAGEDGLGNNLLALAINAARAKATVGEISDALEKVYGRHQAEIRTIA MMAR_2303|M.marinum_M AHGRAGDDGLGNNLLALAIDAARAKATVGEISDALEQVYGRHQAEIRTIA MUL_1506|M.ulcerans_Agy99 AHGRAGDDGLGNNLLALAIDAARAKATVGEISDALEQVYGRHQAEIRTIA * ** :**:****:*** :*******.***:*:***:*:****: Mvan_2763|M.vanbaalenii_PYR-1 GVYRDEVG---MAGNVSSATELVEKFAEADGRRPRILVAKMGQDGHDRGQ Mflv_3649|M.gilvum_PYR-GCK GVYRDEVG---MASNVSGATELVEKFAEADGRRPRILVAKMGQDGHDRGQ MSMEG_3159|M.smegmatis_MC2_155 GVYRDEVG---KGSNIASATELVNKFAEADGRRPRILVAKMGQDGHDRGQ MAB_2711c|M.abscessus_ATCC_199 GVYRDEVGRDGAVSSVTQATELVQKFADADGRRPRVLVAKMGQDGHDRGQ TH_0613|M.thermoresistible__bu GVYRDEVG---KASNIASATELVEKFAEADGRRPRILVAKMGQDGHDRGQ Mb1530|M.bovis_AF2122/97 GVYR---DEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQ Rv1493|M.tuberculosis_H37Rv GVYR---DEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQ MLBr_01799|M.leprae_Br4923 GVYRREVGEAGKATDIANATELVKKFAEADGRRPRILVAKMGQDGHDRGQ MAV_3277|M.avium_104 GVYR---DEAGKATNIATATELVEKFAEADGRRPRILVAKMGQDGHDRGQ MMAR_2303|M.marinum_M GVYRDEVQGGGNITPLSKATELVEKFAEADGRRPRILVAKMGQDGHDRGQ MUL_1506|M.ulcerans_Agy99 GVYRDEVQGGGNITPLSKATELVEKFAEADGRRPRILVAKMGQDGHDRGQ **** :: *****:***:*******:*:************ Mvan_2763|M.vanbaalenii_PYR-1 KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL Mflv_3649|M.gilvum_PYR-GCK KVIATAFADIGFDVDVGSLFSTPDEVARQAADNDVHVVGVSSLAAGHLTL MSMEG_3159|M.smegmatis_MC2_155 KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL MAB_2711c|M.abscessus_ATCC_199 KVIATAFADIGFDVDVGPLFQTPEEVARQAADNDVHVVGVSSLAAGHLTL TH_0613|M.thermoresistible__bu KVIATAFADIGFDVDVGSLFSTPDEVARQAADNDVHVVGVSSLAAGHLTL Mb1530|M.bovis_AF2122/97 KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL Rv1493|M.tuberculosis_H37Rv KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL MLBr_01799|M.leprae_Br4923 KVVATAFADLGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL MAV_3277|M.avium_104 KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL MMAR_2303|M.marinum_M KVIATAFADIGFDVDVGSLFSTPEEVAREAADNDVHVVGVSSLAAGHLTL MUL_1506|M.ulcerans_Agy99 KVIATAFADIGFDVDVGSLFSTPEEVAREAADNDVHVVGVSSLAAGHLTL **:******:*******.**.**:****:********:************ Mvan_2763|M.vanbaalenii_PYR-1 VPALRDALAEVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA Mflv_3649|M.gilvum_PYR-GCK VPALRDALAEVGRPDIMVVVGGVIPPGDFDELYEAGATAIFPPGTVIADA MSMEG_3159|M.smegmatis_MC2_155 VPALRDALAEVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA MAB_2711c|M.abscessus_ATCC_199 VPALRQALAEVGRPDIMIVVGGVIPPGDFDELYQAGAAAIFPPGTVISEA TH_0613|M.thermoresistible__bu VPALRDALAEVGRPDIMIVVGGVIPPGDFEELYRAGATAIYPPGTVIADA Mb1530|M.bovis_AF2122/97 VPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA Rv1493|M.tuberculosis_H37Rv VPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA MLBr_01799|M.leprae_Br4923 VPALRDALADVGRPDIMIVVGGVIPPDDFDELYAAGATAIFPPGTVIAYA MAV_3277|M.avium_104 VPALRDALKEVGRPDIMIVVGGVIPPGDFDELYAAGAAAIFPPGTVIADA MMAR_2303|M.marinum_M VPALRDALAKVGRPDIMIVVGGVIPPGDFDELYAAGATAIYPPGTVIADA MUL_1506|M.ulcerans_Agy99 VPALRDALAKVGRPDIMIVVGGVIPPGDFDELYAAGATAIYPPGTVIADA *****:** .*******:********.**:*** ***:**:******: * Mvan_2763|M.vanbaalenii_PYR-1 AIGLLNKLAERLGYTLS Mflv_3649|M.gilvum_PYR-GCK AIGLLNKLAERLGYSLS MSMEG_3159|M.smegmatis_MC2_155 AIGLLHKLAERLGYELS MAB_2711c|M.abscessus_ATCC_199 AIGLLHKLAERLGYDLT TH_0613|M.thermoresistible__bu AIGLLHKLAERLGYDLS Mb1530|M.bovis_AF2122/97 AIDLLHRLAERLGYTLD Rv1493|M.tuberculosis_H37Rv AIDLLHRLAERLGYTLD MLBr_01799|M.leprae_Br4923 AIGLLHKLAGRLGYTLT MAV_3277|M.avium_104 AIGLLHKLAERLGYDLG MMAR_2303|M.marinum_M AIGLLHKLAERLGYPLD MUL_1506|M.ulcerans_Agy99 AIGLLHKLAERLGYPLD **.**::** **** *