For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1493 (mutB)

annotation: methylmalonyl-CoA mutase
coordinates: 1684005 - 1686257
length: 750

MTTKTPVIGSFAGVPLHSERAAQSPTEAAVHTHVAAAAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAA
EAEGYPLHSFPGEPPFVRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLATHRG
YDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGAVLPILALYVVAAEEQGVAPEQLAG
TIQNDILKEFMVRNTYIYPPKPSMRIISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGV
DYIRAGLNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSAKSLSLRTHSQTSGW
SLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDEALALPTDFSARIARNTQLVLQQESGTTRPIDPWG
GSYYVEWLTHRLARRARAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKYQVPE
DHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAAEQGRAGADGLGNNLLALAIDAARA
QATVGEISEALEKVYGRHRAEIRTISGVYRDEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHD
RGQKVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTLVPALRDALAQVGRPDIM
IVVGGVIPPGDFDELYAAGATAIFPPGTVIADAAIDLLHRLAERLGYTLD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1493mutB-100% (750)methylmalonyl-CoA mutase
M. tuberculosis H37RvRv1492mutA6e-3228.95% (456) methylmalonyl-CoA mutase small subunit
M. tuberculosis H37RvRv1489A-8e-1773.33% (60) hypothetical protein Rv1489A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1530mutB0.0100.00% (750) methylmalonyl-CoA mutase
M. gilvum PYR-GCKMflv_3649-0.087.72% (749) methylmalonyl-CoA mutase
M. leprae Br4923MLBr_01799mutB0.088.90% (748) methylmalonyl-CoA mutase
M. abscessus ATCC 19977MAB_2711c-0.086.19% (746) methylmalonyl-CoA mutase
M. marinum MMMAR_2303mutB0.089.51% (753) methylmalonyl-CoA mutase large subunit, MutB
M. avium 104MAV_3277-0.090.79% (749) methylmalonyl-CoA mutase
M. smegmatis MC2 155MSMEG_3159-0.089.89% (742) methylmalonyl-CoA mutase
M. thermoresistible (build 8)TH_0613mutB0.091.44% (689) PROBABLE METHYLMALONYL-CoA MUTASE LARGE SUBUNIT MUTB (MCM)
M. ulcerans Agy99MUL_1506mutB0.088.98% (753) methylmalonyl-CoA mutase
M. vanbaalenii PYR-1Mvan_2763-0.088.40% (750) methylmalonyl-CoA mutase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_2711c|M.abscessus_ATCC_199      MTDLTDLSESGTI--------LGSFADVPLHGDRVSVAPDTAAVQTAVSE
TH_0613|M.thermoresistible__bu      --------------------------------------------------
Mflv_3649|M.gilvum_PYR-GCK          ----MTVTERRKS--------IDSFAEVPLLGDGAAAAPTQAEAAEQVTA
Mvan_2763|M.vanbaalenii_PYR-1       ----MTAIEPVK---------IDSFGDVPLHGDTAAAAPTYSDVTTQVSA
MSMEG_3159|M.smegmatis_MC2_155      ----MTATTGSE---------IRSFADVPLEGETPAAAATPEARDAQVSA
Rv1493|M.tuberculosis_H37Rv         ----MTTKTP----------VIGSFAGVPLHSERAAQSPTEAAVHTHVAA
Mb1530|M.bovis_AF2122/97            ----MTTKTP----------VIGSFAGVPLHSERAAQSPTEAAVHTHVAA
MLBr_01799|M.leprae_Br4923          ----MTVRDVGGQQDRETTFVVGSFADIPLRSDRVVWPPSEAAVEKHVFS
MAV_3277|M.avium_104                ----MTTTAP----------AVGSFADVPLRSERPVAPATEAAVEEHVAA
MMAR_2303|M.marinum_M               ----MTTTAS----------AIGSFADVPLHGERAVASATEAAVEKQVAA
MUL_1506|M.ulcerans_Agy99           ----MTTTAS----------AIGSFADVPLHGERAVASATEASVEKQVAA
                                                                                      

MAB_2711c|M.abscessus_ATCC_199      AAAAHGYSPEQLDWETPEAITVKPIYTAADREAVRAQGYPLDTFPGQVPF
TH_0613|M.thermoresistible__bu      ------------------------VYIGADRAAAEAAGYPLHTFPGAVPY
Mflv_3649|M.gilvum_PYR-GCK          AAAAHGYAADQSDWTTPEGIDVKPVFVAADRDDVVGAGYPLDSLPGEPPF
Mvan_2763|M.vanbaalenii_PYR-1       AAAAHGYTADQLDWATPEGIDVKPVYIGADRDAIVAAGYPLDSLPGEPPF
MSMEG_3159|M.smegmatis_MC2_155      AASAHGYAPDQLTWTTPEGIDVKPVYIAADRDEAVEAGYPLDSFPGAPPF
Rv1493|M.tuberculosis_H37Rv         AAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPF
Mb1530|M.bovis_AF2122/97            AAAAHGYTPEQLVWHTPEGIDVTPVYIAADRAAAEAEGYPLHSFPGEPPF
MLBr_01799|M.leprae_Br4923          AASAHGYTVDQLHWHTPEGIDVKPVYIAADRAAAEAGGYPLHSFPGEPPY
MAV_3277|M.avium_104                IAAAHLYTPDQLHWHTPEDIAVKPVYIGADRAAVEADGYPLHTFPGEPPF
MMAR_2303|M.marinum_M               TAAAHGYATDQLRWQTPEGIEVKPVYIGADRRAAQADGYPVNSFPGEPPY
MUL_1506|M.ulcerans_Agy99           TAAAHGYATDQLRWQTPEGIEVKPVYIGADRRAAQADGYPVNSFPGEPPY
                                                            :: .***      ***:.::**  *:

MAB_2711c|M.abscessus_ATCC_199      LRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
TH_0613|M.thermoresistible__bu      IRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
Mflv_3649|M.gilvum_PYR-GCK          VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
Mvan_2763|M.vanbaalenii_PYR-1       VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
MSMEG_3159|M.smegmatis_MC2_155      IRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
Rv1493|M.tuberculosis_H37Rv         VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
Mb1530|M.bovis_AF2122/97            VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
MLBr_01799|M.leprae_Br4923          LRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
MAV_3277|M.avium_104                VRGPYPTMYVNQPWTIRQYAGFSTAAESNAFYRRNLAAGQKGLSVAFDLA
MMAR_2303|M.marinum_M               VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
MUL_1506|M.ulcerans_Agy99           VRGPYPTMYVNQPWTIRQYAGFSTAADSNAFYRRNLAAGQKGLSVAFDLA
                                    :*************************:***********************

MAB_2711c|M.abscessus_ATCC_199      THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLGSVSVSMTMNGA
TH_0613|M.thermoresistible__bu      THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLGSVSVSMTMNGA
Mflv_3649|M.gilvum_PYR-GCK          THRGYDSDHPRVAGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
Mvan_2763|M.vanbaalenii_PYR-1       THRGYDSDHPRVAGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
MSMEG_3159|M.smegmatis_MC2_155      THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
Rv1493|M.tuberculosis_H37Rv         THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
Mb1530|M.bovis_AF2122/97            THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
MLBr_01799|M.leprae_Br4923          THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSAVSVSMTMNGA
MAV_3277|M.avium_104                THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSTVSVSMTMNGA
MMAR_2303|M.marinum_M               THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
MUL_1506|M.ulcerans_Agy99           THRGYDSDHPRVQGDVGMAGVAIDSILDMRQLFDGIDLSSVSVSMTMNGA
                                    ************ *************************.:**********

MAB_2711c|M.abscessus_ATCC_199      VLPILALYVVAAEEQGVGTEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
TH_0613|M.thermoresistible__bu      VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
Mflv_3649|M.gilvum_PYR-GCK          VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
Mvan_2763|M.vanbaalenii_PYR-1       VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MSMEG_3159|M.smegmatis_MC2_155      VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKESMRI
Rv1493|M.tuberculosis_H37Rv         VLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRI
Mb1530|M.bovis_AF2122/97            VLPILALYVVAAEEQGVAPEQLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MLBr_01799|M.leprae_Br4923          VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPEPSMRI
MAV_3277|M.avium_104                VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MMAR_2303|M.marinum_M               VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
MUL_1506|M.ulcerans_Agy99           VLPILALYVVAAEEQGVPPEKLAGTIQNDILKEFMVRNTYIYPPKPSMRI
                                    ***************** .*:***********************: ****

MAB_2711c|M.abscessus_ATCC_199      ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG
TH_0613|M.thermoresistible__bu      ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG
Mflv_3649|M.gilvum_PYR-GCK          ISDIFGYTSAKMPKFNSISISGYHIQEAGATADLELGYTLADGVEYIKAG
Mvan_2763|M.vanbaalenii_PYR-1       ISDIFGYTSAKMPKFNSISISGYHIQEAGATADLELGYTLADGVEYIKAG
MSMEG_3159|M.smegmatis_MC2_155      ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVEYIKAG
Rv1493|M.tuberculosis_H37Rv         ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAG
Mb1530|M.bovis_AF2122/97            ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIRAG
MLBr_01799|M.leprae_Br4923          ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
MAV_3277|M.avium_104                ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
MMAR_2303|M.marinum_M               ISDIFAYTSAKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
MUL_1506|M.ulcerans_Agy99           ISDIFAYTSVKMPKFNSISISGYHIQEAGATADLELAYTLADGVDYIKAG
                                    *****.***.**************************.*******:**:**

MAB_2711c|M.abscessus_ATCC_199      LAGGLDIDVFAPRLSFFWAIGMNFFMEVAKLRAGRLLWSELVAQFDPKSS
TH_0613|M.thermoresistible__bu      LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFDPKNS
Mflv_3649|M.gilvum_PYR-GCK          LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAEFDPKSS
Mvan_2763|M.vanbaalenii_PYR-1       LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSQFEPKSA
MSMEG_3159|M.smegmatis_MC2_155      LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSEFEPKSE
Rv1493|M.tuberculosis_H37Rv         LNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSA
Mb1530|M.bovis_AF2122/97            LNAGLDIDSFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAQFAPKSA
MLBr_01799|M.leprae_Br4923          LDAGLDIDTFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFGPQSP
MAV_3277|M.avium_104                LDAELDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVSQFNPKNP
MMAR_2303|M.marinum_M               LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFEPKNS
MUL_1506|M.ulcerans_Agy99           LDAGLDIDKFAPRLSFFWGIGMNFFMEVAKLRAGRLLWSELVAKFEPKNS
                                    * . **** *********.***********************::* *:. 

MAB_2711c|M.abscessus_ATCC_199      KSQSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
TH_0613|M.thermoresistible__bu      KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
Mflv_3649|M.gilvum_PYR-GCK          KSLSLRTHSQTSGWSLTAQDAFNNVARTCIEAMAATQGHTQSLHTNALDE
Mvan_2763|M.vanbaalenii_PYR-1       KSLSLRTHSQTSGWSLTAQDAFNNVARTCVEAMAATQGHTQSLHTNALDE
MSMEG_3159|M.smegmatis_MC2_155      KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
Rv1493|M.tuberculosis_H37Rv         KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
Mb1530|M.bovis_AF2122/97            KSLSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
MLBr_01799|M.leprae_Br4923          KSLSLRTHSQTSGWSLTAQDPFNNVARTCIEAMAATQGHTQSLHTNALDE
MAV_3277|M.avium_104                KSLSLRTHSQTSGWSLTAQDAFNNVARTCIEAMAATQGHTQSLHTNALDE
MMAR_2303|M.marinum_M               KSRSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
MUL_1506|M.ulcerans_Agy99           KSRSLRTHSQTSGWSLTAQDVFNNVARTCIEAMAATQGHTQSLHTNALDE
                                    ** ***************** ********:********************

MAB_2711c|M.abscessus_ATCC_199      ALALPTDFSARIARNTQLLIQQESGTCRPIDPWGGSYYVEWLTHQLASRA
TH_0613|M.thermoresistible__bu      ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAERA
Mflv_3649|M.gilvum_PYR-GCK          ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTYQLAEKA
Mvan_2763|M.vanbaalenii_PYR-1       ALALPTDFSARIARNTQLLLQQESGTTRPIDPWAGSYYVESLTYQLAEKA
MSMEG_3159|M.smegmatis_MC2_155      ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAERA
Rv1493|M.tuberculosis_H37Rv         ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRA
Mb1530|M.bovis_AF2122/97            ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHRLARRA
MLBr_01799|M.leprae_Br4923          ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHQLAARA
MAV_3277|M.avium_104                ALALPTDFSARIARNTQLVLQQESGTTRPIDPWGGSYYVEWLTHHLARKA
MMAR_2303|M.marinum_M               ALALPTDFSARIARNTQLLLQQESGTTRPIDPWGGSYYVEWLTHQLAQRA
MUL_1506|M.ulcerans_Agy99           ALALPTDFSARIARNTQLLLQQESGTTRPIDPWAGSYYVEWLTHQLAQRA
                                    ******************::****** ******.****** **::** :*

MAB_2711c|M.abscessus_ATCC_199      REHIREVTEAGGMAQAIDQGIPKLRIEEAAARTQARIDSGRQPVIGVNKY
TH_0613|M.thermoresistible__bu      RAHIREVDEHGGMAQAISDGVPKLRIEEAAARTQARIDSGAQPVIGVNKY
Mflv_3649|M.gilvum_PYR-GCK          RGHIREIAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVIGVNKY
Mvan_2763|M.vanbaalenii_PYR-1       RAHIAEIAEYGGMAQAIDAGIPKLRIEEAAARTQARIDSGQQTVIGVNRY
MSMEG_3159|M.smegmatis_MC2_155      RAHIKEVAEHGGMAQAISEGIPKLRIEEAAARTQARIDSGAQPVIGVNKY
Rv1493|M.tuberculosis_H37Rv         RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKY
Mb1530|M.bovis_AF2122/97            RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGQQPVVGVNKY
MLBr_01799|M.leprae_Br4923          RTHIAEVAEHGGMAAAISDGIPKLRIEEAAARTQARIDSGRQPVVGVNKY
MAV_3277|M.avium_104                RAHIAEVAEHGGMAQAISDGIPKLRIEEAAARTQARIDSGIQPVIGVNKY
MMAR_2303|M.marinum_M               RAHINEVAELGGMAAAISEGIPKLRIEEAAARTQARIDSGQQPVIGVNKY
MUL_1506|M.ulcerans_Agy99           RAHINEVAELGGMAAAIGEGIPKLRIEEAAARTQARIDSGQQPVIGVNKY
                                    * ** *: * **** **. *:******************* *.*:***:*

MAB_2711c|M.abscessus_ATCC_199      QVAEDQQIEVLKVENSRVRAEQLAKLQQLRAERDDDAVQAALAELTRAAA
TH_0613|M.thermoresistible__bu      QVDEDHEIEVLKVDNSRVRAEQLAKLEQLRAERDQAAVDAALDELSRAAA
Mflv_3649|M.gilvum_PYR-GCK          QVDEDHEIEVLKVENSRVRAEQLAKLERLRRERDETATQAALAELTRAAA
Mvan_2763|M.vanbaalenii_PYR-1       QVDEDHEIEVLKVENSRVRAEQIAKLERLRSERDDAATQAALAELTRAAA
MSMEG_3159|M.smegmatis_MC2_155      QVDEDTEIEVLKVENSRVRAEQIAKLQQLRAERDEAATQAALDELTRAAA
Rv1493|M.tuberculosis_H37Rv         QVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAA
Mb1530|M.bovis_AF2122/97            QVPEDHEIEVLKVENSRVRAEQLAKLQRLRAGRDEPAVRAALAELTRAAA
MLBr_01799|M.leprae_Br4923          QVDQDHEIEVLKVENSRVRAEQVAKLQQLRANRDQLAVDAALAELSGAAG
MAV_3277|M.avium_104                QVEEDQEVEVLKVENSRVRAEQLAKLKELRDSRDQSAVDAALAELSRAAA
MMAR_2303|M.marinum_M               QVDEDQQIEVLKVENSRVRAEQLAKLQELRAGRDQAAVDAALAELTRAAA
MUL_1506|M.ulcerans_Agy99           QVDEDQQIEVLKVENSRVRAEQLAKLQELRAGRDQAAVDAALAELTRAAA
                                    ** :* ::*****:********:***:.**  **: *. *** **: **.

MAB_2711c|M.abscessus_ATCC_199      DSGRAGEDGLGNNLMALAINAARHKATVGEISDALEKVYGRHQAEIRTIS
TH_0613|M.thermoresistible__bu      ATGPAGADGLGNNLMALAINAARAKATVGEISSALERVWGRHQAEIRTIS
Mflv_3649|M.gilvum_PYR-GCK          ASGVAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIA
Mvan_2763|M.vanbaalenii_PYR-1       ASGAAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIA
MSMEG_3159|M.smegmatis_MC2_155      ASGPAGEDGLGNNLLALAIDAARAKATVGEISDALEKVYGRHQAEIRTIS
Rv1493|M.tuberculosis_H37Rv         EQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTIS
Mb1530|M.bovis_AF2122/97            EQGRAGADGLGNNLLALAIDAARAQATVGEISEALEKVYGRHRAEIRTIS
MLBr_01799|M.leprae_Br4923          AHGRAG-----DNLLALAINAARVQATVGEISDALERVYGRHQAKIRTIT
MAV_3277|M.avium_104                AQGRAGEDGLGNNLLALAINAARAKATVGEISDALEKVYGRHQAEIRTIA
MMAR_2303|M.marinum_M               AHGRAGDDGLGNNLLALAIDAARAKATVGEISDALEQVYGRHQAEIRTIA
MUL_1506|M.ulcerans_Agy99           AHGRAGDDGLGNNLLALAIDAARAKATVGEISDALEQVYGRHQAEIRTIA
                                      * **     :**:****:*** :*******.***:*:***:*:****:

MAB_2711c|M.abscessus_ATCC_199      GVYRDEVGRDGAVSSVTQATELVQKFADADGRRPRVLVAKMGQDGHDRGQ
TH_0613|M.thermoresistible__bu      GVYRDEVG---KASNIASATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
Mflv_3649|M.gilvum_PYR-GCK          GVYRDEVG---MASNVSGATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
Mvan_2763|M.vanbaalenii_PYR-1       GVYRDEVG---MAGNVSSATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
MSMEG_3159|M.smegmatis_MC2_155      GVYRDEVG---KGSNIASATELVNKFAEADGRRPRILVAKMGQDGHDRGQ
Rv1493|M.tuberculosis_H37Rv         GVYR---DEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQ
Mb1530|M.bovis_AF2122/97            GVYR---DEVGKAPNIAAATELVEKFAEADGRRPRILIAKMGQDGHDRGQ
MLBr_01799|M.leprae_Br4923          GVYRREVGEAGKATDIANATELVKKFAEADGRRPRILVAKMGQDGHDRGQ
MAV_3277|M.avium_104                GVYR---DEAGKATNIATATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
MMAR_2303|M.marinum_M               GVYRDEVQGGGNITPLSKATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
MUL_1506|M.ulcerans_Agy99           GVYRDEVQGGGNITPLSKATELVEKFAEADGRRPRILVAKMGQDGHDRGQ
                                    ****           :: *****:***:*******:*:************

MAB_2711c|M.abscessus_ATCC_199      KVIATAFADIGFDVDVGPLFQTPEEVARQAADNDVHVVGVSSLAAGHLTL
TH_0613|M.thermoresistible__bu      KVIATAFADIGFDVDVGSLFSTPDEVARQAADNDVHVVGVSSLAAGHLTL
Mflv_3649|M.gilvum_PYR-GCK          KVIATAFADIGFDVDVGSLFSTPDEVARQAADNDVHVVGVSSLAAGHLTL
Mvan_2763|M.vanbaalenii_PYR-1       KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL
MSMEG_3159|M.smegmatis_MC2_155      KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL
Rv1493|M.tuberculosis_H37Rv         KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL
Mb1530|M.bovis_AF2122/97            KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL
MLBr_01799|M.leprae_Br4923          KVVATAFADLGFDVDVGSLFSTPEEVARQAADNDVHVIGVSSLAAGHLTL
MAV_3277|M.avium_104                KVIATAFADIGFDVDVGSLFSTPEEVARQAADNDVHVVGVSSLAAGHLTL
MMAR_2303|M.marinum_M               KVIATAFADIGFDVDVGSLFSTPEEVAREAADNDVHVVGVSSLAAGHLTL
MUL_1506|M.ulcerans_Agy99           KVIATAFADIGFDVDVGSLFSTPEEVAREAADNDVHVVGVSSLAAGHLTL
                                    **:******:*******.**.**:****:********:************

MAB_2711c|M.abscessus_ATCC_199      VPALRQALAEVGRPDIMIVVGGVIPPGDFDELYQAGAAAIFPPGTVISEA
TH_0613|M.thermoresistible__bu      VPALRDALAEVGRPDIMIVVGGVIPPGDFEELYRAGATAIYPPGTVIADA
Mflv_3649|M.gilvum_PYR-GCK          VPALRDALAEVGRPDIMVVVGGVIPPGDFDELYEAGATAIFPPGTVIADA
Mvan_2763|M.vanbaalenii_PYR-1       VPALRDALAEVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
MSMEG_3159|M.smegmatis_MC2_155      VPALRDALAEVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
Rv1493|M.tuberculosis_H37Rv         VPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
Mb1530|M.bovis_AF2122/97            VPALRDALAQVGRPDIMIVVGGVIPPGDFDELYAAGATAIFPPGTVIADA
MLBr_01799|M.leprae_Br4923          VPALRDALADVGRPDIMIVVGGVIPPDDFDELYAAGATAIFPPGTVIAYA
MAV_3277|M.avium_104                VPALRDALKEVGRPDIMIVVGGVIPPGDFDELYAAGAAAIFPPGTVIADA
MMAR_2303|M.marinum_M               VPALRDALAKVGRPDIMIVVGGVIPPGDFDELYAAGATAIYPPGTVIADA
MUL_1506|M.ulcerans_Agy99           VPALRDALAKVGRPDIMIVVGGVIPPGDFDELYAAGATAIYPPGTVIADA
                                    *****:** .*******:********.**:*** ***:**:******: *

MAB_2711c|M.abscessus_ATCC_199      AIGLLHKLAERLGYDLT
TH_0613|M.thermoresistible__bu      AIGLLHKLAERLGYDLS
Mflv_3649|M.gilvum_PYR-GCK          AIGLLNKLAERLGYSLS
Mvan_2763|M.vanbaalenii_PYR-1       AIGLLNKLAERLGYTLS
MSMEG_3159|M.smegmatis_MC2_155      AIGLLHKLAERLGYELS
Rv1493|M.tuberculosis_H37Rv         AIDLLHRLAERLGYTLD
Mb1530|M.bovis_AF2122/97            AIDLLHRLAERLGYTLD
MLBr_01799|M.leprae_Br4923          AIGLLHKLAGRLGYTLT
MAV_3277|M.avium_104                AIGLLHKLAERLGYDLG
MMAR_2303|M.marinum_M               AIGLLHKLAERLGYPLD
MUL_1506|M.ulcerans_Agy99           AIGLLHKLAERLGYPLD
                                    **.**::** **** *