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M. smegmatis MC2 155 MSMEG_3099 (pgl)

annotation: 6-phosphogluconolactonase
coordinates: 3173171 - 3173905
length: 244

SDTVIERHADTAALVAAAGDRLVDAISSAIGERGQATIVLTGGGTGIGLLKRVRERSGEIDWSKVHIYWG
DERFVPQDDDERNDKQAREALLDHIGIPPVNVHAMAASDGEFGDDLEAAAAGYAQLLSANFDSSVPGFDV
HLLGMGGEGHVNSLFPDTDAVRETERLVVGVSDSPKPPPRRITLTLPAVQNSREVWLVVSGEAKADAVAA
AVGGADPVDIPAAGAVGRERTVWLVDEAAAAKL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3099pgl-100% (244)6-phosphogluconolactonase
M. smegmatis MC2 155MSMEG_2118nagB2e-0925.31% (241) glucosamine-6-phosphate deaminase
M. smegmatis MC2 155MSMEG_0501-5e-0926.09% (253) glucosamine-6-phosphate deaminase 1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1480cdevB4e-8966.39% (241) 6-phosphogluconolactonase
M. gilvum PYR-GCKMflv_3696-1e-10476.99% (239) 6-phosphogluconolactonase
M. tuberculosis H37RvRv1445cdevB4e-8966.39% (241) 6-phosphogluconolactonase
M. leprae Br4923MLBr_00579pgl1e-8765.56% (241) putative 6-phosphogluconolactonase
M. abscessus ATCC 19977MAB_2763-1e-9669.11% (246) 6-phosphogluconolactonase
M. marinum MMMAR_2250devB6e-9268.03% (244) 6-phosphogluconolactonase DevB
M. avium 104MAV_3331pgl3e-8867.49% (243) 6-phosphogluconolactonase
M. thermoresistible (build 8)TH_0335pgl1e-10275.93% (241) 6-phosphogluconolactonase
M. ulcerans Agy99MUL_1840devB4e-9268.03% (244) 6-phosphogluconolactonase DevB
M. vanbaalenii PYR-1Mvan_2716-1e-10580.00% (240) 6-phosphogluconolactonase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3696|M.gilvum_PYR-GCK          -MTMNIETYPDTEALVAATGDRLVEAIKAAIAARDVAAIALTGGGTGIGL
Mvan_2716|M.vanbaalenii_PYR-1       -MTREIETYSGTAALVAAAGDRLVASIKNAVEGRSSAHIVLTGGGTGIGL
MSMEG_3099|M.smegmatis_MC2_155      MSDTVIERHADTAALVAAAGDRLVDAISSAIGERGQATIVLTGGGTGIGL
TH_0335|M.thermoresistible__bu      -MSTFVETHPDTATLVTAAGDRLVEAINAATSARGEAVIVLTGGGSGIAL
MLBr_00579|M.leprae_Br4923          -MSASVEIFSDSKTMVGAAGKRLASTIQSAVAARERALIVLTGGSSGIGL
MAV_3331|M.avium_104                -MSTRIEIFPDSQALVTAAAARLVDTIADAVAARGRALIVLTGGGNGIGL
Mb1480c|M.bovis_AF2122/97           -MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIAL
Rv1445c|M.tuberculosis_H37Rv        -MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIAL
MMAR_2250|M.marinum_M               -MSLDVEIFPDSDMLIGAAGQRLIQTIGSAVAERGQALIVLTGGGNGIGL
MUL_1840|M.ulcerans_Agy99           -MSLDVEIFPDSDMLIGAAGQRLIQTIGSAVAERGQALIVLTGGGNGIGL
MAB_2763|M.abscessus_ATCC_1997      MSETIIEKYADTDALVTAAGDRLASAITGALAERGKAMIVLTGGGTGIAL
                                         :* ...:  :: *:. **  :*  *   *  * *.****..**.*

Mflv_3696|M.gilvum_PYR-GCK          LRRVGERGDEIDWSKVHIYWGDERFVPADDDERNEKQAREALLDHVGIPE
Mvan_2716|M.vanbaalenii_PYR-1       LGRVAERSGEIDWSKVHIYWGDERFVAHDDDERNEKQAREALLDHVDIPA
MSMEG_3099|M.smegmatis_MC2_155      LKRVRERSGEIDWSKVHIYWGDERFVPQDDDERNDKQAREALLDHIGIPP
TH_0335|M.thermoresistible__bu      LKRVGERAGEIDWSKVRLYWGDERYVPAADDERNEKQAREALLDHIDIPA
MLBr_00579|M.leprae_Br4923          LRDLATRGQQIDWSRVHLFWGDERYVPKDDDERNEKQARVALLDHIDIPP
MAV_3331|M.avium_104                LKSLAGR--PIDWSAVHLFWGDERYVPEDDDERNEKQAREALLSHVDIPS
Mb1480c|M.bovis_AF2122/97           LRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPS
Rv1445c|M.tuberculosis_H37Rv        LRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPS
MMAR_2250|M.marinum_M               LRYLGSQGPQIDWSKVHLFWGDDRYVPEDDDERNDKQAREALLDHVDIPA
MUL_1840|M.ulcerans_Agy99           LRYLGSQGPQIDWSKVHLFWGDDRYVPEDDDERNDKQAREALLDHVDIPA
MAB_2763|M.abscessus_ATCC_1997      LKHLRDVASGLDWTNVHVFWGDDRYVPKTDPERNAWQAWEALLEHVNFPL
                                    *  :      ::*: *:::***:*:*.  * ***  **  ***.*:.:* 

Mflv_3696|M.gilvum_PYR-GCK          ANVHVMAPSDGEFGDAIDAAAEAYAQVLAEAG--PDPTPAFDVHLLGMGP
Mvan_2716|M.vanbaalenii_PYR-1       ANVHAMAASDGEFGDALDAAAEAYAQLLTEAGG-AEPTPAFDVHLLGMGG
MSMEG_3099|M.smegmatis_MC2_155      VNVHAMAASDGEFGDDLEAAAAGYAQLL-SANF-DSSVPGFDVHLLGMGG
TH_0335|M.thermoresistible__bu      ANVHPMAASDGEFGDDIAAAAAAYEQVL---------PAEFDVHLLGMGG
MLBr_00579|M.leprae_Br4923          SQVHPMPAGDGEFGNDLEAAALAYEQLLAAYAAPGYPTPNFDVHLMGMGP
MAV_3331|M.avium_104                SQVHPMPASDGEFGSDLAAAALAYEQLLAANAAPGQPVPNFDVHLLGMGP
Mb1480c|M.bovis_AF2122/97           NQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGP
Rv1445c|M.tuberculosis_H37Rv        NQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGP
MMAR_2250|M.marinum_M               SQVHPMAASDGEFGADLDAAALAYEQVLAASAVPGNRAPDFDVHLLGMGP
MUL_1840|M.ulcerans_Agy99           SQVHPMAASDGEFGADLDAAALAYEQVLAASAVPGNRAPDFDVHLLGMGP
MAB_2763|M.abscessus_ATCC_1997      RNMHAMPNSESEYGTDLDAAALAYEQLLAANAEPGQDCPAFDVHLLGMGG
                                     ::* *. .:.::*  : *** .* *:*          . *****:*** 

Mflv_3696|M.gilvum_PYR-GCK          EGHVNSLFPDTDAVKESKRFVVGVTDCPKPPPRRITLTLPAVQRSREVWL
Mvan_2716|M.vanbaalenii_PYR-1       EGHVNSLFPDTAAVRETERLVVGVADSPKPPPRRITLTLPAITRSREVWL
MSMEG_3099|M.smegmatis_MC2_155      EGHVNSLFPDTDAVRETERLVVGVSDSPKPPPRRITLTLPAVQNSREVWL
TH_0335|M.thermoresistible__bu      EGHINSLFPDTPAVRETERLVVPVTDSPKPPPRRISLTLPAVRRARQVWL
MLBr_00579|M.leprae_Br4923          EGHINSLFPNTVAVRETSRMVVGVRNSPKPPPERITLTLNAIQRSREVWL
MAV_3331|M.avium_104                EGHINSLFPDTPAVLETTRMVVPVEDSPKPPPQRITLTLPAIARSREVWL
Mb1480c|M.bovis_AF2122/97           EGHINSLFPHSPAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWL
Rv1445c|M.tuberculosis_H37Rv        EGHINSLFPHSPAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWL
MMAR_2250|M.marinum_M               EGHINSLFPGTQAVRETTRLVVPVGDSPKPPPQRITLTLPAIQRSREVWL
MUL_1840|M.ulcerans_Agy99           EGHINSLFPGTQAVRETTRLVVPVGDSPKPPPQRITLTLPAIQRSREVWL
MAB_2763|M.abscessus_ATCC_1997      EGHINSLFPHTDAVKETQRLVVAVPDSPKPPPQRITLTLPAIQRSREVWL
                                    ***:***** : ** *: *:** * :.*****.**:*** *: .:*:***

Mflv_3696|M.gilvum_PYR-GCK          VVSGEGKADAVAAAIGGAQPVDIPAAGAVGTEATVWLLDEAAASKL----
Mvan_2716|M.vanbaalenii_PYR-1       VVSGAAKADAVAAAIGGADPVDIPAAGAVGTEATVWLLDEDAASKL----
MSMEG_3099|M.smegmatis_MC2_155      VVSGEAKADAVAAAVGGADPVDIPAAGAVGRERTVWLVDEAAAAKL----
TH_0335|M.thermoresistible__bu      VVSGAAKADAVAAAVNGADPVDIPAAGAVGREATVWLLDEEAASRLDR--
MLBr_00579|M.leprae_Br4923          MVSGTAKADAVAAAMGGAPSASIPAAGAVGLETTLWLLDEEAAAKIPG--
MAV_3331|M.avium_104                MVSGAGKADAVAAAINGAAPVSVPAAGAVGLDTTLWLLDREAAAKLPPGT
Mb1480c|M.bovis_AF2122/97           LVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKLPS--
Rv1445c|M.tuberculosis_H37Rv        LVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKLPS--
MMAR_2250|M.marinum_M               MVSGGTKAEAVAAAIGGADPVLLPAAGAIGRESTRWLLDRDAAARLPG--
MUL_1840|M.ulcerans_Agy99           MVSGGTKAEAVAAAIGGADPVLLPAAGAIGRESTRWLLDRDAAARLPG--
MAB_2763|M.abscessus_ATCC_1997      VVSGEAKADAVAAAVGGADPVDVPAAGAKGIERTVWLLDEAAASQLG---
                                    :***  **:*****:.** .. :***** * : * **:*. **:::    

Mflv_3696|M.gilvum_PYR-GCK          ----
Mvan_2716|M.vanbaalenii_PYR-1       ----
MSMEG_3099|M.smegmatis_MC2_155      ----
TH_0335|M.thermoresistible__bu      ----
MLBr_00579|M.leprae_Br4923          ----
MAV_3331|M.avium_104                AVQG
Mb1480c|M.bovis_AF2122/97           ----
Rv1445c|M.tuberculosis_H37Rv        ----
MMAR_2250|M.marinum_M               ----
MUL_1840|M.ulcerans_Agy99           ----
MAB_2763|M.abscessus_ATCC_1997      ----