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MEVIILPDPGRIGSLAADAITALITRKPDAVLGLATGSSPLAVYDELVSRYEAGQISFRQARGFTLDEYV GLPADHPERYRNVIDTAFAARVDFAPGAVQGPDGLADDIPAACAAYEAAIRDAGGVDLQILGIGTDGHIA FNEPGSSLASRTRIKTLTRQTRVDNARFFGGDLDQVPTHCLTQGLGTIMEARHLILIAMGRSKAEAVHHL VEGAVSAMWPATVLQMHPHVTVLLDDAAAQRLQLVDYYRETYRAKPAWQGI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2118 | nagB | - | 100% (261) | glucosamine-6-phosphate deaminase |
| M. smegmatis MC2 155 | MSMEG_0501 | - | 3e-54 | 49.58% (240) | glucosamine-6-phosphate deaminase 1 |
| M. smegmatis MC2 155 | MSMEG_3099 | pgl | 2e-09 | 25.31% (241) | 6-phosphogluconolactonase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1480c | devB | 4e-08 | 26.97% (241) | 6-phosphogluconolactonase |
| M. gilvum PYR-GCK | Mflv_3696 | - | 6e-09 | 25.73% (241) | 6-phosphogluconolactonase |
| M. tuberculosis H37Rv | Rv1445c | devB | 4e-08 | 26.97% (241) | 6-phosphogluconolactonase |
| M. leprae Br4923 | MLBr_00579 | pgl | 5e-11 | 26.94% (245) | putative 6-phosphogluconolactonase |
| M. abscessus ATCC 19977 | MAB_2763 | - | 3e-08 | 25.73% (241) | 6-phosphogluconolactonase |
| M. marinum M | MMAR_2250 | devB | 4e-09 | 26.46% (257) | 6-phosphogluconolactonase DevB |
| M. avium 104 | MAV_3331 | pgl | 7e-07 | 24.90% (253) | 6-phosphogluconolactonase |
| M. thermoresistible (build 8) | TH_0335 | pgl | 3e-12 | 29.06% (234) | 6-phosphogluconolactonase |
| M. ulcerans Agy99 | MUL_1840 | devB | 3e-09 | 26.46% (257) | 6-phosphogluconolactonase DevB |
| M. vanbaalenii PYR-1 | Mvan_2716 | - | 6e-07 | 25.42% (240) | 6-phosphogluconolactonase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00579|M.leprae_Br4923 MSAS-VEIFSDSKTMVGAAGKRLASTIQSAVAARERALIVLTGGSSGIGL
MAV_3331|M.avium_104 MSTR-IEIFPDSQALVTAAAARLVDTIADAVAARGRALIVLTGGGNGIGL
Mb1480c|M.bovis_AF2122/97 MSSS-IEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIAL
Rv1445c|M.tuberculosis_H37Rv MSSS-IEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIAL
MMAR_2250|M.marinum_M MSLD-VEIFPDSDMLIGAAGQRLIQTIGSAVAERGQALIVLTGGGNGIGL
MUL_1840|M.ulcerans_Agy99 MSLD-VEIFPDSDMLIGAAGQRLIQTIGSAVAERGQALIVLTGGGNGIGL
MAB_2763|M.abscessus_ATCC_1997 MSETIIEKYADTDALVTAAGDRLASAITGALAERGKAMIVLTGGGTGIAL
Mflv_3696|M.gilvum_PYR-GCK MTMN-IETYPDTEALVAATGDRLVEAIKAAIAARDVAAIALTGGGTGIGL
Mvan_2716|M.vanbaalenii_PYR-1 MTRE-IETYSGTAALVAAAGDRLVASIKNAVEGRSSAHIVLTGGGTGIGL
TH_0335|M.thermoresistible__bu MSTF-VETHPDTATLVTAAGDRLVEAINAATSARGEAVIVLTGGGSGIAL
MSMEG_2118|M.smegmatis_MC2_155 ---MEVIILPDP----GRIGSLAADAITALITRKPDAVLGLATGSSPLAV
: ... . :* : * : *: *.. :.:
MLBr_00579|M.leprae_Br4923 LRDLATRGQ--QIDWSRVHLFWGDERY-VPKDDDERNEKQARVALLDHID
MAV_3331|M.avium_104 LKSLAGR----PIDWSAVHLFWGDERY-VPEDDDERNEKQAREALLSHVD
Mb1480c|M.bovis_AF2122/97 LRYLSAQAQ--QIEWSKVHLFWGDERY-VPEDDDERNLKQARRALLNHVD
Rv1445c|M.tuberculosis_H37Rv LRYLSAQAQ--QIEWSKVHLFWGDERY-VPEDDDERNLKQARRALLNHVD
MMAR_2250|M.marinum_M LRYLGSQGP--QIDWSKVHLFWGDDRY-VPEDDDERNDKQAREALLDHVD
MUL_1840|M.ulcerans_Agy99 LRYLGSQGP--QIDWSKVHLFWGDDRY-VPEDDDERNDKQAREALLDHVD
MAB_2763|M.abscessus_ATCC_1997 LKHLRDVAS--GLDWTNVHVFWGDDRY-VPKTDPERNAWQAWEALLEHVN
Mflv_3696|M.gilvum_PYR-GCK LRRVGERGD--EIDWSKVHIYWGDERF-VPADDDERNEKQAREALLDHVG
Mvan_2716|M.vanbaalenii_PYR-1 LGRVAERSG--EIDWSKVHIYWGDERF-VAHDDDERNEKQAREALLDHVD
TH_0335|M.thermoresistible__bu LKRVGERAG--EIDWSKVRLYWGDERY-VPAADDERNEKQAREALLDHID
MSMEG_2118|M.smegmatis_MC2_155 YDELVSRYEAGQISFRQARGFTLDEYVGLPADHPERYRNVIDTAFAARVD
: :.: .: : *: :. . ** *: ::.
MLBr_00579|M.leprae_Br4923 IPPSQVHPMPAGDGEFGNDLEAAALAYEQLLAAYAAPGYPTPNFDVHLMG
MAV_3331|M.avium_104 IPSSQVHPMPASDGEFGSDLAAAALAYEQLLAANAAPGQPVPNFDVHLLG
Mb1480c|M.bovis_AF2122/97 IPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLG
Rv1445c|M.tuberculosis_H37Rv IPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLG
MMAR_2250|M.marinum_M IPASQVHPMAASDGEFGADLDAAALAYEQVLAASAVPGNRAPDFDVHLLG
MUL_1840|M.ulcerans_Agy99 IPASQVHPMAASDGEFGADLDAAALAYEQVLAASAVPGNRAPDFDVHLLG
MAB_2763|M.abscessus_ATCC_1997 FPLRNMHAMPNSESEYGTDLDAAALAYEQLLAANAEPGQDCPAFDVHLLG
Mflv_3696|M.gilvum_PYR-GCK IPEANVHVMAPSDGEFGDAIDAAAEAYAQVLAEAG--PDPTPAFDVHLLG
Mvan_2716|M.vanbaalenii_PYR-1 IPAANVHAMAASDGEFGDALDAAAEAYAQLLTEAGG-AEPTPAFDVHLLG
TH_0335|M.thermoresistible__bu IPAANVHPMAASDGEFGDDIAAAAAAYEQVL---------PAEFDVHLLG
MSMEG_2118|M.smegmatis_MC2_155 FAPG---AVQGPDG-LADDIPAACAAYEAAIRDAG-------GVDLQILG
:. : :. . : **. ** : .*::::*
MLBr_00579|M.leprae_Br4923 MGPEGHINSLFPNTVAVRETSRMVVGVR-----------NSPKPPPERIT
MAV_3331|M.avium_104 MGPEGHINSLFPDTPAVLETTRMVVPVE-----------DSPKPPPQRIT
Mb1480c|M.bovis_AF2122/97 MGPEGHINSLFPHSPAVLESTRMVVAVD-----------DSPKPPPRRIT
Rv1445c|M.tuberculosis_H37Rv MGPEGHINSLFPHSPAVLESTRMVVAVD-----------DSPKPPPRRIT
MMAR_2250|M.marinum_M MGPEGHINSLFPGTQAVRETTRLVVPVG-----------DSPKPPPQRIT
MUL_1840|M.ulcerans_Agy99 MGPEGHINSLFPGTQAVRETTRLVVPVG-----------DSPKPPPQRIT
MAB_2763|M.abscessus_ATCC_1997 MGGEGHINSLFPHTDAVKETQRLVVAVP-----------DSPKPPPQRIT
Mflv_3696|M.gilvum_PYR-GCK MGPEGHVNSLFPDTDAVKESKRFVVGVT-----------DCPKPPPRRIT
Mvan_2716|M.vanbaalenii_PYR-1 MGGEGHVNSLFPDTAAVRETERLVVGVA-----------DSPKPPPRRIT
TH_0335|M.thermoresistible__bu MGGEGHINSLFPDTPAVRETERLVVPVT-----------DSPKPPPRRIS
MSMEG_2118|M.smegmatis_MC2_155 IGTDGHIAFNEPGSSLASRTRIKTLTRQTRVDNARFFGGDLDQVPTHCLT
:* :**: * : . .: .: : : *.. ::
MLBr_00579|M.leprae_Br4923 LTLNAIQRSREVWLMVSGTAKADAVAAAMGGAPSASIPAAGAVGLETTLW
MAV_3331|M.avium_104 LTLPAIARSREVWLMVSGAGKADAVAAAINGAAPVSVPAAGAVGLDTTLW
Mb1480c|M.bovis_AF2122/97 LTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLW
Rv1445c|M.tuberculosis_H37Rv LTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLW
MMAR_2250|M.marinum_M LTLPAIQRSREVWLMVSGGTKAEAVAAAIGGADPVLLPAAGAIGRESTRW
MUL_1840|M.ulcerans_Agy99 LTLPAIQRSREVWLMVSGGTKAEAVAAAIGGADPVLLPAAGAIGRESTRW
MAB_2763|M.abscessus_ATCC_1997 LTLPAIQRSREVWLVVSGEAKADAVAAAVGGADPVDVPAAGAKGIERTVW
Mflv_3696|M.gilvum_PYR-GCK LTLPAVQRSREVWLVVSGEGKADAVAAAIGGAQPVDIPAAGAVGTEATVW
Mvan_2716|M.vanbaalenii_PYR-1 LTLPAITRSREVWLVVSGAAKADAVAAAIGGADPVDIPAAGAVGTEATVW
TH_0335|M.thermoresistible__bu LTLPAVRRARQVWLVVSGAAKADAVAAAVNGADPVDIPAAGAVGREATVW
MSMEG_2118|M.smegmatis_MC2_155 QGLGTIMEARHLILIAMGRSKAEAVHHLVEGAVSAMWPATVLQMHPHVTV
* :: .:*.: *:. * **:** : ** .. **: .
MLBr_00579|M.leprae_Br4923 LLDEEAAAKIPG-----------------
MAV_3331|M.avium_104 LLDREAAAKLPPGTAVQG-----------
Mb1480c|M.bovis_AF2122/97 LLDRDAAAKLPS-----------------
Rv1445c|M.tuberculosis_H37Rv LLDRDAAAKLPS-----------------
MMAR_2250|M.marinum_M LLDRDAAARLPG-----------------
MUL_1840|M.ulcerans_Agy99 LLDRDAAARLPG-----------------
MAB_2763|M.abscessus_ATCC_1997 LLDEAAASQLG------------------
Mflv_3696|M.gilvum_PYR-GCK LLDEAAASKL-------------------
Mvan_2716|M.vanbaalenii_PYR-1 LLDEDAASKL-------------------
TH_0335|M.thermoresistible__bu LLDEEAASRLDR-----------------
MSMEG_2118|M.smegmatis_MC2_155 LLDDAAAQRLQLVDYYRETYRAKPAWQGI
*** ** ::