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TPTVDITADTRAAGEAVAARIAALIRTTPDAVIGVATGSSPLPVYTALAGYVDAGLDVTRVTWCALDEYL GLPTHHPQSYRAELERALVAPLHLDPASLRVPDGAADDPDKAAADYEAFLAERGVDLQILGIGRNGHIGF NEPGTSFTSTTHRARLTESTRKANARFFSGLDEVPHECLTQGLATIMRARRIELIAGGEQKADAVARALH GPITEQCPASILQRHPDVHVTLDAGAASLLVEHSARR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0501 | - | - | 100% (248) | glucosamine-6-phosphate deaminase 1 |
| M. smegmatis MC2 155 | MSMEG_2118 | nagB | 2e-54 | 49.58% (240) | glucosamine-6-phosphate deaminase |
| M. smegmatis MC2 155 | MSMEG_3099 | pgl | 5e-09 | 26.09% (253) | 6-phosphogluconolactonase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1480c | devB | 9e-10 | 28.34% (247) | 6-phosphogluconolactonase |
| M. gilvum PYR-GCK | Mflv_3696 | - | 9e-10 | 25.95% (262) | 6-phosphogluconolactonase |
| M. tuberculosis H37Rv | Rv1445c | devB | 9e-10 | 28.34% (247) | 6-phosphogluconolactonase |
| M. leprae Br4923 | MLBr_00579 | pgl | 1e-09 | 26.58% (237) | putative 6-phosphogluconolactonase |
| M. abscessus ATCC 19977 | MAB_2763 | - | 6e-10 | 27.31% (249) | 6-phosphogluconolactonase |
| M. marinum M | MMAR_2250 | devB | 3e-08 | 26.12% (245) | 6-phosphogluconolactonase DevB |
| M. avium 104 | MAV_3331 | pgl | 7e-09 | 27.50% (240) | 6-phosphogluconolactonase |
| M. thermoresistible (build 8) | TH_0335 | pgl | 4e-09 | 26.78% (239) | 6-phosphogluconolactonase |
| M. ulcerans Agy99 | MUL_1840 | devB | 2e-08 | 26.12% (245) | 6-phosphogluconolactonase DevB |
| M. vanbaalenii PYR-1 | Mvan_2716 | - | 8e-07 | 25.48% (263) | 6-phosphogluconolactonase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00579|M.leprae_Br4923 -MSASVEIFSDSKTMVGAAGKRLASTIQSAVAARERALIVLTGGSSGIGL
MAV_3331|M.avium_104 -MSTRIEIFPDSQALVTAAAARLVDTIADAVAARGRALIVLTGGGNGIGL
Mb1480c|M.bovis_AF2122/97 -MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIAL
Rv1445c|M.tuberculosis_H37Rv -MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIAL
MMAR_2250|M.marinum_M -MSLDVEIFPDSDMLIGAAGQRLIQTIGSAVAERGQALIVLTGGGNGIGL
MUL_1840|M.ulcerans_Agy99 -MSLDVEIFPDSDMLIGAAGQRLIQTIGSAVAERGQALIVLTGGGNGIGL
Mflv_3696|M.gilvum_PYR-GCK -MTMNIETYPDTEALVAATGDRLVEAIKAAIAARDVAAIALTGGGTGIGL
Mvan_2716|M.vanbaalenii_PYR-1 -MTREIETYSGTAALVAAAGDRLVASIKNAVEGRSSAHIVLTGGGTGIGL
TH_0335|M.thermoresistible__bu -MSTFVETHPDTATLVTAAGDRLVEAINAATSARGEAVIVLTGGGSGIAL
MAB_2763|M.abscessus_ATCC_1997 MSETIIEKYADTDALVTAAGDRLASAITGALAERGKAMIVLTGGGTGIAL
MSMEG_0501|M.smegmatis_MC2_155 -MTPTVDITADT----RAAGEAVAARIAALIRTTPDAVIGVATGSSPLPV
:: ..: *:. : * * * :: *.. : :
MLBr_00579|M.leprae_Br4923 LRDLATRG-QQIDWSRVHLFWGDERY-VPKDDDERNEKQARVALLDHIDI
MAV_3331|M.avium_104 LKSLAGR---PIDWSAVHLFWGDERY-VPEDDDERNEKQAREALLSHVDI
Mb1480c|M.bovis_AF2122/97 LRYLSAQA-QQIEWSKVHLFWGDERY-VPEDDDERNLKQARRALLNHVDI
Rv1445c|M.tuberculosis_H37Rv LRYLSAQA-QQIEWSKVHLFWGDERY-VPEDDDERNLKQARRALLNHVDI
MMAR_2250|M.marinum_M LRYLGSQG-PQIDWSKVHLFWGDDRY-VPEDDDERNDKQAREALLDHVDI
MUL_1840|M.ulcerans_Agy99 LRYLGSQG-PQIDWSKVHLFWGDDRY-VPEDDDERNDKQAREALLDHVDI
Mflv_3696|M.gilvum_PYR-GCK LRRVGERG-DEIDWSKVHIYWGDERF-VPADDDERNEKQAREALLDHVGI
Mvan_2716|M.vanbaalenii_PYR-1 LGRVAERS-GEIDWSKVHIYWGDERF-VAHDDDERNEKQAREALLDHVDI
TH_0335|M.thermoresistible__bu LKRVGERA-GEIDWSKVRLYWGDERY-VPAADDERNEKQAREALLDHIDI
MAB_2763|M.abscessus_ATCC_1997 LKHLRDVA-SGLDWTNVHVFWGDDRY-VPKTDPERNAWQAWEALLEHVNF
MSMEG_0501|M.smegmatis_MC2_155 YTALAGYVDAGLDVTRVTWCALDEYLGLPTHHPQSYRAELERALVAPLHL
: :: : * *: :. . : : **: : :
MLBr_00579|M.leprae_Br4923 PPSQVHPMPAGDGEFGNDLEAAALAYEQLLAAYAAPGYPTPNFDVHLMGM
MAV_3331|M.avium_104 PSSQVHPMPASDGEFGSDLAAAALAYEQLLAANAAPGQPVPNFDVHLLGM
Mb1480c|M.bovis_AF2122/97 PSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGM
Rv1445c|M.tuberculosis_H37Rv PSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGM
MMAR_2250|M.marinum_M PASQVHPMAASDGEFGADLDAAALAYEQVLAASAVPGNRAPDFDVHLLGM
MUL_1840|M.ulcerans_Agy99 PASQVHPMAASDGEFGADLDAAALAYEQVLAASAVPGNRAPDFDVHLLGM
Mflv_3696|M.gilvum_PYR-GCK PEANVHVMAPSDGEFGDAIDAAAEAYAQVLAEAG--PDPTPAFDVHLLGM
Mvan_2716|M.vanbaalenii_PYR-1 PAANVHAMAASDGEFGDALDAAAEAYAQLLTEAGG-AEPTPAFDVHLLGM
TH_0335|M.thermoresistible__bu PAANVHPMAASDGEFGDDIAAAAAAYEQVL---------PAEFDVHLLGM
MAB_2763|M.abscessus_ATCC_1997 PLRNMHAMPNSESEYGTDLDAAALAYEQLLAANAEPGQDCPAFDVHLLGM
MSMEG_0501|M.smegmatis_MC2_155 DPASLR---VPDG-AADDPDKAAADYEAFLAERG--------VDLQILGI
.:: :. . ** * .* .*::::*:
MLBr_00579|M.leprae_Br4923 GPEGHINSLFPNTVAVRETSRMVVGVRNSPK----------PPPERITLT
MAV_3331|M.avium_104 GPEGHINSLFPDTPAVLETTRMVVPVEDSPK----------PPPQRITLT
Mb1480c|M.bovis_AF2122/97 GPEGHINSLFPHSPAVLESTRMVVAVDDSPK----------PPPRRITLT
Rv1445c|M.tuberculosis_H37Rv GPEGHINSLFPHSPAVLESTRMVVAVDDSPK----------PPPRRITLT
MMAR_2250|M.marinum_M GPEGHINSLFPGTQAVRETTRLVVPVGDSPK----------PPPQRITLT
MUL_1840|M.ulcerans_Agy99 GPEGHINSLFPGTQAVRETTRLVVPVGDSPK----------PPPQRITLT
Mflv_3696|M.gilvum_PYR-GCK GPEGHVNSLFPDTDAVKESKRFVVGVTDCPK----------PPPRRITLT
Mvan_2716|M.vanbaalenii_PYR-1 GGEGHVNSLFPDTAAVRETERLVVGVADSPK----------PPPRRITLT
TH_0335|M.thermoresistible__bu GGEGHINSLFPDTPAVRETERLVVPVTDSPK----------PPPRRISLT
MAB_2763|M.abscessus_ATCC_1997 GGEGHINSLFPHTDAVKETQRLVVAVPDSPK----------PPPQRITLT
MSMEG_0501|M.smegmatis_MC2_155 GRNGHIGFNEPGTSFTSTTHRARLTESTRKANARFFSGLDEVPHECLTQG
* :**:. * : . : * : * . ::
MLBr_00579|M.leprae_Br4923 LNAIQRSREVWLMVSGTAKADAVAAAMGGAPSASIPAAGAVGLETTLWLL
MAV_3331|M.avium_104 LPAIARSREVWLMVSGAGKADAVAAAINGAAPVSVPAAGAVGLDTTLWLL
Mb1480c|M.bovis_AF2122/97 LPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLL
Rv1445c|M.tuberculosis_H37Rv LPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLL
MMAR_2250|M.marinum_M LPAIQRSREVWLMVSGGTKAEAVAAAIGGADPVLLPAAGAIGRESTRWLL
MUL_1840|M.ulcerans_Agy99 LPAIQRSREVWLMVSGGTKAEAVAAAIGGADPVLLPAAGAIGRESTRWLL
Mflv_3696|M.gilvum_PYR-GCK LPAVQRSREVWLVVSGEGKADAVAAAIGGAQPVDIPAAGAVGTEATVWLL
Mvan_2716|M.vanbaalenii_PYR-1 LPAITRSREVWLVVSGAAKADAVAAAIGGADPVDIPAAGAVGTEATVWLL
TH_0335|M.thermoresistible__bu LPAVRRARQVWLVVSGAAKADAVAAAVNGADPVDIPAAGAVGREATVWLL
MAB_2763|M.abscessus_ATCC_1997 LPAIQRSREVWLVVSGEAKADAVAAAVGGADPVDVPAAGAKGIERTVWLL
MSMEG_0501|M.smegmatis_MC2_155 LATIMRARRIELIAGGEQKADAVARALHGPITEQCPASILQRHPDVHVTL
* :: *:*.: *:..* **:*** *: *. . **: . *
MLBr_00579|M.leprae_Br4923 DEEAAAKIPG------
MAV_3331|M.avium_104 DREAAAKLPPGTAVQG
Mb1480c|M.bovis_AF2122/97 DRDAAAKLPS------
Rv1445c|M.tuberculosis_H37Rv DRDAAAKLPS------
MMAR_2250|M.marinum_M DRDAAARLPG------
MUL_1840|M.ulcerans_Agy99 DRDAAARLPG------
Mflv_3696|M.gilvum_PYR-GCK DEAAASKL--------
Mvan_2716|M.vanbaalenii_PYR-1 DEDAASKL--------
TH_0335|M.thermoresistible__bu DEEAASRLDR------
MAB_2763|M.abscessus_ATCC_1997 DEAAASQLG-------
MSMEG_0501|M.smegmatis_MC2_155 DAGAASLLVEHSARR-
* **: :