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MSAFRTVLPRNRDDVAKSLADIVGGGGDALIVGGGTLTVPALVRGDITATHVVDLGKADLDGIEFGQEAA EIGASVSYQHILESPRMRRDLPLLYRLCSGITGGIQIRNQGTVVGALCAARPQSDIPAALVALGAEVLIH STSGTRIVDAQTFLRGAEQTDLATGEFVTAVRVPWPATAGFGYVKLKSAESSWPVVTAAAVLPGHVVLGG VAKVPQLIPLPDPGMVRTVVAEHVDRIPPTQRWADLRADWNYRRRVAPEIAARAVEQGVDHV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2950 | - | - | 100% (272) | carbon monoxide dehydrogenase, medium chain |
| M. smegmatis MC2 155 | MSMEG_0744 | - | 2e-18 | 26.04% (265) | carbon monoxide dehydrogenase medium chain |
| M. smegmatis MC2 155 | MSMEG_5882 | - | 2e-17 | 28.85% (260) | carbon monoxide dehydrogenase medium chain |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0382c | - | 7e-16 | 26.24% (282) | carbon monoxyde dehydrogenase medium subunit |
| M. gilvum PYR-GCK | Mflv_1571 | - | 2e-15 | 27.80% (277) | carbon-monoxide dehydrogenase (acceptor) |
| M. tuberculosis H37Rv | Rv0375c | - | 7e-16 | 26.24% (282) | carbon monoxyde dehydrogenase medium subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0655 | coxM | 1e-17 | 26.18% (275) | carbon monoxyde dehydrogenase (medium chain), CoxM |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0174 | - | 1e-17 | 25.27% (277) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (MEDIUM CHAIN) |
| M. ulcerans Agy99 | MUL_0587 | coxM_2 | 2e-15 | 25.90% (278) | aerobic-type carbon monoxide dehydrogenase, CoxM_2 |
| M. vanbaalenii PYR-1 | Mvan_5185 | - | 5e-18 | 29.30% (273) | carbon-monoxide dehydrogenase (acceptor) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0382c|M.bovis_AF2122/97 --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
Rv0375c|M.tuberculosis_H37Rv --------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPE
MMAR_0655|M.marinum_M MQVPGPFEYERATSVDHAIGLLDRLGEGARLVAGGHSLLPMMKLRIANPE
TH_0174|M.thermoresistible__bu MQVPGPFEYERATSVDHAIGLLDRLGDGAMIVAGGHSLLPMMKLRIANPE
Mflv_1571|M.gilvum_PYR-GCK -MKAAPFAYHRPDTVADAVSLLGEYGDDAKILAGGQSLVPMLAMRLTHFE
Mvan_5185|M.vanbaalenii_PYR-1 -MKAAPFAYHRPDTVADAVSMLGEFGDDAKILAGGQSLVPMLAMRLTHFE
MUL_0587|M.ulcerans_Agy99 -MKPASFDYHRPDTAEEAVDLLAELGEDAKILPGGQSLVPMLSMRLAFFD
MSMEG_2950|M.smegmatis_MC2_155 MSAFRTVLPRNRDDVAKSLADIVGGGGDALIVGGGTLTVPALVRGDITAT
.:: : * .* :: ** :* :
Mb0382c|M.bovis_AF2122/97 YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
Rv0375c|M.tuberculosis_H37Rv YLVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIF
MMAR_0655|M.marinum_M YLVDINDLAPELGYVIT----DPTLVRIGAMARHREILESEALAAVCPIF
TH_0174|M.thermoresistible__bu YLVDINDLAGELGYIVV----NADAVRIGAMTRHREALESAELAQCCPIF
Mflv_1571|M.gilvum_PYR-GCK NLIDISRIEELRNIELRNG--ADSSVRIGAGTPHALVGMDDEVAESVPLL
Mvan_5185|M.vanbaalenii_PYR-1 NLIDISRVDELRNIEPRG-----DAVRIGAGTPHALVGMDDEVAESVPLL
MUL_0587|M.ulcerans_Agy99 HLIDISRLGELQGIRLRD-----DQLWIGAGTPDSKVGTNSQVHQSIPLL
MSMEG_2950|M.smegmatis_MC2_155 HVVDLG-KADLDGIEFG-----QEAAEIGASVSYQHILESPRMRRDLPLL
::*:. . :** . . : *::
Mb0382c|M.bovis_AF2122/97 RDAER-VIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSG
Rv0375c|M.tuberculosis_H37Rv RDAER-VIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGPSG
MMAR_0655|M.marinum_M RDAER-VIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLARGSSG
TH_0174|M.thermoresistible__bu ADAER-VIADPVVRNRGTVGGSLCQADPAEDLSTVCTVLDAVCVVRGPAG
Mflv_1571|M.gilvum_PYR-GCK TLATP-HIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEIEATSGRG
Mvan_5185|M.vanbaalenii_PYR-1 TLSTP-HIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEMEATSARG
MUL_0587|M.ulcerans_Agy99 ARATP-YIGHFQIRNRGTLGGSIAHADAAGEYPTVALTLDAVMEVLSPRG
MSMEG_2950|M.smegmatis_MC2_155 YRLCSGITGGIQIRNQGTVVGALCAARPQSDIPAALVALGAEVLIHSTSG
. :*.:**: *::. * . : .:. .*.* . *
Mb0382c|M.bovis_AF2122/97 EREIAIDDFLVGPYETALAHNEVLIEVRIPLRHNTS-SAYAKVERRVGDW
Rv0375c|M.tuberculosis_H37Rv EREIAIDDFLVGPYETALAHNEVLIEVRIPLRHNTS-SAYAKVERRVGDW
MMAR_0655|M.marinum_M EREIAIDEFQAGPYETTLAPSEMLVEVRIPVRHNTS-SAYAKVERRVGDW
TH_0174|M.thermoresistible__bu RREIGIDDFLVGPYETALAHNEILLEVKIPLRPNSS-NAYAKVERRVGDW
Mflv_1571|M.gilvum_PYR-GCK TRRIPAAEFFTGLWETALASDEILTAVSFPVWSGRCGFAVQEFARRHGDF
Mvan_5185|M.vanbaalenii_PYR-1 TRRIPAAEFFTGLWETALAADEILTAVSFPVWTGHCGFAVQEFARRHGDF
MUL_0587|M.ulcerans_Agy99 HRKIPAAEFFTGLWETAMEPDEVLTGVRFPTWTGKSGFAMREFSRRHGDF
MSMEG_2950|M.smegmatis_MC2_155 TRIVDAQTFLRGAEQTDLATGEFVTAVRVP-WPATAGFGYVKLKSAESSW
* : * * :* : .*.: * .* . . :. ..:
Mb0382c|M.bovis_AF2122/97 AITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEV
Rv0375c|M.tuberculosis_H37Rv AITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEV
MMAR_0655|M.marinum_M AVTAAGAAVTLNN-DTITAARVGLTAVNPDPAALAELAAALVGRPANEDT
TH_0174|M.thermoresistible__bu AVTAAGAAVTLDG-QTVTAARIGLTAVNPDAAALAEISRRLTGRPATEET
Mflv_1571|M.gilvum_PYR-GCK AIAGATVAVALDEDDTVTRCGIGMLGMGSTPERGTAAEAAVLGRPVADIT
Mvan_5185|M.vanbaalenii_PYR-1 AIAGATLAVELDGRDRVARCGIGLLGMGSTPERGTPAEQAVVGRPVTDIT
MUL_0587|M.ulcerans_Agy99 AIAGAAVAVQLDDEHRVSRCAIGLLGLGPTPRRATAAEAAVLGKPIDELV
MSMEG_2950|M.smegmatis_MC2_155 PVVTA---------AAVLPGHVVLGGVAKVPQLIPLPDPGMVRTVVAEHV
.:. * : : : .: . . : : .
Mb0382c|M.bovis_AF2122/97 FAEAGRRAAQACTPVT-DVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPA
Rv0375c|M.tuberculosis_H37Rv FAEAGRRAAQACTPVT-DVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPA
MMAR_0655|M.marinum_M FAEAGRRAGQACEPVT-DIRGTADYKRHLAAELTIRTLRSAVGRVRNQPA
TH_0174|M.thermoresistible__bu FAEAGRLAAQACEPVT-DVRGTADYKRHLAAELTTRTLRTAVQRIQQRHG
Mflv_1571|M.gilvum_PYR-GCK AEELGRLAVSTLHDIPADLQGSAAYRSRVCATMVARAWSEATTAARHTTE
Mvan_5185|M.vanbaalenii_PYR-1 AEEVGRLAVSELHDVPADLQGRPAYRSKVGATMVARAWSQATTAALETRE
MUL_0587|M.ulcerans_Agy99 PEQIGQSAMSGLDDIASDLQGPASYRAQVGAVMTTRAWSRAVQEAN--AE
MSMEG_2950|M.smegmatis_MC2_155 DRIP-------PTQRWADLRADWNYRRRVAPEIAARAVEQGVDHV-----
*::. *: :: :. *: ..
Mb0382c|M.bovis_AF2122/97 APEA--
Rv0375c|M.tuberculosis_H37Rv APEA--
MMAR_0655|M.marinum_M PEGN--
TH_0174|M.thermoresistible__bu GAQPCR
Mflv_1571|M.gilvum_PYR-GCK ALHA--
Mvan_5185|M.vanbaalenii_PYR-1 ALNA--
MUL_0587|M.ulcerans_Agy99 TAHA--
MSMEG_2950|M.smegmatis_MC2_155 ------