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M. smegmatis MC2 155 MSMEG_2909 (-)

KIVAADVLVTAPGRNYVTLKITTDDGLVGWGDATLNGRELAVASYLRDHVCPQLIGRDAQRIEDTWQYFY
KGAYWRRGPVTMTAIAAVDIALWDIKGKAAGMPLYQLLGGAARDGVMVYGHASGASLEEMLDDFAGYVDR
GYRAVRAQCAVPGMGKVYGVHPGSSLYEPASAHLPAEESWETGPYLRFAPRMLGAVRERFGFDVHLLHDV
HHRLSPIEAARLGRDVEEHRLFWMEDPTPAEDQEAFRLIRQNTTTPLAVGEVFNSIWDCQHLITERLIDY
IRTSVSHAGGVTHLRRIFALAELYGVRTGSHGAGDLSPVSFAAALHIDMSVPNFGVQEYMGHVEPADEVF
RTNWTFQNGLMHPGDAPGLGVEVDEQAAARFPYDPKSLPVNRRADGSVHDW*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_2909	-	-	100% (402)	starvation-sensing protein RspA
M. smegmatis MC2 155	MSMEG_6177	-	3e-51	31.63% (411)	galactonate dehydratase
M. smegmatis MC2 155	MSMEG_0126	-	1e-25	26.23% (366)	mandelate racemase/muconate lactonizing enzyme

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_1357	-	2e-12	23.04% (369)	mandelate racemase/muconate lactonizing protein
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	MAV_3096	-	5e-20	24.80% (375)	mandelate racemase/muconate lactonizing enzyme
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_1029	-	5e-09	20.70% (372)	mandelate racemase/muconate lactonizing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1357|M.gilvum_PYR-GCK          ---MKITAVDAIPFAIPYTKPLKFASGEVHTAEHVLVRVHTDEGVVGVAE
Mvan_1029|M.vanbaalenii_PYR-1       MAPIRVTGARITPVAFADPPLLNTVGVHQPYALRAIIQLDTDAGLVGLGE
MAV_3096|M.avium_104                --------MTPDPAIDEVTARVYQIPTDAPEADGTLSWSSTTLVLAEVAA
MSMEG_2909|M.smegmatis_MC2_155      -----------------MKIVAADVLVTAPGRNYVTLKITTDDGLVGWGD
                                                                      .     *   :.  . 

Mflv_1357|M.gilvum_PYR-GCK          APPRPFTYGETQDGILAVIR-QIFAPQIVGLTLTEREVVNARLARTVGNP
Mvan_1029|M.vanbaalenii_PYR-1       TYADTRHLARLRAAAEAITGLDVFALNRIRASIGSRLEGDTTAVGTAGMI
MAV_3096|M.avium_104                GGRRGIGYTYADGACAALIT-GALAGSVTGHSALDVPARWQAMVRAMRNN
MSMEG_2909|M.smegmatis_MC2_155      ATLNGR-----ELAVASYLR-DHVCPQLIGRDAQRIEDTWQYFYKGAYWR
                                                 .  :      .. .                       

Mflv_1357|M.gilvum_PYR-GCK          TAKAAVD-------MAIWDALGRSLDLSVSALLGGYG-DHMRVSHML-GF
Mvan_1029|M.vanbaalenii_PYR-1       TSASVVDQVLSPFEVACLDVQGQSLGRPVSDLLGGAVRDAVPFSAYL-FY
MAV_3096|M.avium_104                GRPGLVSCAISAVDTALWDLKGKLLGLPVCRLLGMAH-DSVPIYGSG-GF
MSMEG_2909|M.smegmatis_MC2_155      RGP-VTMTAIAAVDIALWDIKGKAAGMPLYQLLGGAARDGVMVYGHASGA
                                         .         *  *  *:  . .:  ***    * : .       

Mflv_1357|M.gilvum_PYR-GCK          D----------------TPDTMVAEAERIRDEYGIS-----------TFK
Mvan_1029|M.vanbaalenii_PYR-1       KWAGHPNAEPDRFGEAMDPNGLVAQARRIIDEYGFT-----------AIK
MAV_3096|M.avium_104                TS--------------YDDNATRAQLERWVHEWRIP-----------RVK
MSMEG_2909|M.smegmatis_MC2_155      SLEEMLDDFAGYVDRGYRAVRAQCAVPGMGKVYGVHPGSSLYEPASAHLP
                                                           .      . : .             . 

Mflv_1357|M.gilvum_PYR-GCK          VKVGR---RPVTLDTAVVRALRERFGDTVELYVDGNRGWTASESLRALKD
Mvan_1029|M.vanbaalenii_PYR-1       LKGGV---FPPEEEMAAIEALSRNFPG-LPLRLDPNAAWTPHTAVKVASG
MAV_3096|M.avium_104                IKIGESWGSHERRDLDRIALARTVIGPDTELYVDANGGYRRKQAIRMAHA
MSMEG_2909|M.smegmatis_MC2_155      AEESWETGPYLRFAPRMLGAVRERFGFDVHLLHDVHHRLSPIEAARLGRD
                                     : .             :      :     *  * :       : :    

Mflv_1357|M.gilvum_PYR-GCK          MADLDLLFAEELCPADDVLGRRWLVEHTEIPFIADESVPTPADVTREVLG
Mvan_1029|M.vanbaalenii_PYR-1       LAGILEYLED---PTPGLAGMAEVAQQAPMPLATNMCVVAFDQLAPAVTK
MAV_3096|M.avium_104                MAGHDVTWFEEPVSSDDLAGLREVRDQVSADVTAGEYGYDLAYFHRMLAA
MSMEG_2909|M.smegmatis_MC2_155      VEEHRLFWMEDPTPAEDQEAFRLIRQNTTTPLAVGEVFNSIWDCQHLITE
                                    :        :   .: .  .   : ::.   . ..            :  

Mflv_1357|M.gilvum_PYR-GCK          -GSATAISIKTARTGFTGSRRVHHLAEGLGLEVVMGNQIDGQLGTACAVA
Mvan_1029|M.vanbaalenii_PYR-1       NAVRVVLSDHHYWGGLQRSRLLAGICDTFGLGLSMHSNSHLGISLAAMVH
MAV_3096|M.avium_104                DAVDCLQIDVTRCGGITDWLRAAAVAAAHNVDVSGHCAPNLHAHVATAVA
MSMEG_2909|M.smegmatis_MC2_155      RLIDYIRTSVSHAGGVTHLRRIFALAELYGVRTGSHGAGDLSP-VSFAAA
                                                  *.        :.   .:        .     :  . 

Mflv_1357|M.gilvum_PYR-GCK          FGAAFELTSRRAGELSNFLDMSDDLLTHPLRIRDGRLHVPPG-PGLGIEI
Mvan_1029|M.vanbaalenii_PYR-1       LAGATPNLT-YACDTHWPWKTEDVVKDGALAFVDGAVPVPTS-PGLGVEI
MAV_3096|M.avium_104                N-------LRHLEYFHDHHRIERMFFDGALSPQGGVLRPDQQRPGFGLEF
MSMEG_2909|M.smegmatis_MC2_155      LHIDMSVPNFGVQEYMGHVEPADEVFRTNWTFQNGLMHPGDA-PGLGVEV
                                                            .        .* :      **:*:*.

Mflv_1357|M.gilvum_PYR-GCK          DPDKLDHYRTDH----------------------------
Mvan_1029|M.vanbaalenii_PYR-1       DDDALDALHEQYVRCGIRDRDDTGYMRTVDPSFEPAGPRW
MAV_3096|M.avium_104                KQRDADRYRMR-----------------------------
MSMEG_2909|M.smegmatis_MC2_155      DEQAAARFPYDPKSLPVNRRADGSVHDW------------
                                    .