For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_2677 (-)

annotation: large membrane protein
coordinates: 2754283 - 2755590
length: 435

RRPTEASGSPRTHTTKPSGTGGVFGWLGDVVVRWPWLVIGCWIALAVALPPMFPTLAEATQKHPVAPIPA
SAPSMVATQQMTAAFHEAGSENVLLVLLTDEHGLGPDDEQVYRTVVGRLRQDGRDVLWLQEFLGTPQLRE
TLSSQDRKAWLLPIGLSGDVGSPESYAAYTRVAGIVDHAVAGSTLTAHLTGPAATLADSIEVGLRDQIKI
EIAIVALLLTILVIVYRKPATILLPVLMIGVSLGVAQAVVAGAAQLGLGVSNQTITLLSGLMAGAGTDYA
VFLISRYHDFLRLGADSDQAVKSALSSIGKVIAASAATVGVTFLGMTFASLELFATIGPALAIAIGVAFL
AAVTLLPAIIVLAGRRGWVSPRREITARFWRRSGIRIVRRPVTNLVASLMVLLVRDPPRRVWRVLPLGRM
GTWDRSHRGGIQTS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2677--100% (435)large membrane protein
M. smegmatis MC2 155MSMEG_0410-e-12157.74% (381) MmpL protein
M. smegmatis MC2 155MSMEG_4741-e-10249.08% (381) MmpL protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3853cmmpL81e-13458.56% (403) integral membrane transport protein
M. gilvum PYR-GCKMflv_0403-1e-12759.42% (382) transport protein
M. tuberculosis H37RvRv3823cmmpL81e-13358.31% (403) integral membrane transport protein
M. leprae Br4923MLBr_01231mmpL101e-12560.90% (376) hypothetical protein MLBr_01231
M. abscessus ATCC 19977MAB_0937c-1e-12857.82% (377) MmpL family protein
M. marinum MMMAR_2342-1e-10048.88% (403) MmpL family transport protein
M. avium 104MAV_1761-1e-13260.55% (398) MmpL10 protein
M. thermoresistible (build 8)TH_2203mmpL81e-12156.01% (391) PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN
M. ulcerans Agy99MUL_3688mmpL4_14e-4328.38% (370) transmembrane transport protein MmpL4_1
M. vanbaalenii PYR-1Mvan_0271-1e-12559.10% (379) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2342|M.marinum_M               ----------------------MSDSEAARAGGFFDKLSRFVIQKPFVVI
TH_2203|M.thermoresistible__bu      ----------------------MGGTETPTGRGFFGRLGDFVIRFPLIVI
Mflv_0403|M.gilvum_PYR-GCK          ----------------------------------MRRLADVVVRWPWAVI
Mvan_0271|M.vanbaalenii_PYR-1       ----------------------------------MRRLADLVVRWPWAVI
MAB_0937c|M.abscessus_ATCC_199      ----------------------------------MRRLADLVVRWPWVVI
MAV_1761|M.avium_104                ----------------------MSPTAPAGDEVEMRRIADFVVRWPWLVI
MSMEG_2677|M.smegmatis_MC2_155      ----------MRRPTEASGSPRTHTTKPSGTGGVFGWLGDVVVRWPWLVI
Mb3853c|M.bovis_AF2122/97           ---MCDVLMQPVRTPRPSTNLRSKPLRPTGDGGVFPRLGRLIVRRPWVVI
Rv3823c|M.tuberculosis_H37Rv        ---MCDVLMQPVRTPRPSTNLRSKPLRPTGDGGVFPRLGRLIVRRPWVVI
MLBr_01231|M.leprae_Br4923          -----------------------------------------------MVI
MUL_3688|M.ulcerans_Agy99           MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVPII
                                                                                    :*

MMAR_2342|M.marinum_M               AIWISLAAIPALMFPPLMEAAAGKNNSAALPDDAPTMVASKEMAKTFEGK
TH_2203|M.thermoresistible__bu      GLWVGLAVVLVATVPPLAEVAAR-NPVSVLPEDAPVMVTSREMSEAFD--
Mflv_0403|M.gilvum_PYR-GCK          GVWIALAVALPLSFPSLGQMAAK-NPLQILPADAPSSVTAQKMAEAFD--
Mvan_0271|M.vanbaalenii_PYR-1       AVWVAMAVALPLSFPSLGEMAQK-HPLVILPSDAPSSVTAAKMAEAFQ--
MAB_0937c|M.abscessus_ATCC_199      GAWVALAIALPLTFPSLTEMAEK-HPLAILPADAPSSVTAKKMTEAFH--
MAV_1761|M.avium_104                GFWAALAVALPLAFPSLAEMAQK-HPLAILPGNAPSNVAARQMTEAFH--
MSMEG_2677|M.smegmatis_MC2_155      GCWIALAVALPPMFPTLAEATQK-HPVAPIPASAPSMVATQQMTAAFH--
Mb3853c|M.bovis_AF2122/97           AFWVALAGLLAPTVPSLDAISQR-HPVAILPSDAPVLVSTRQMTAAFR--
Rv3823c|M.tuberculosis_H37Rv        AFWVALAGLLAPTVPSLDAISQR-HPVAILPSDAPVLVSTRQMTAAFR--
MLBr_01231|M.leprae_Br4923          GCWTLLALMLPMTVPSLTELTQR-HPVVILPVDAPSSVAAKKISQAFH--
MUL_3688|M.ulcerans_Agy99           LGWVLLTVLVNVVVPSLEVVSEQ-HSAPMTPMDAPSMKAMMRLGHNFR--
                                      *  ::      .*.*   :   :     * .**   :  .:   *   

MMAR_2342|M.marinum_M               SNKKDAKAKPGSKPKEDPSDGSQLLVILTDENGLGPGDLAAYTKLVEKLR
TH_2203|M.thermoresistible__bu      ----------------DSGGDNLLLVVMTDEEGLGPEDEKAYQKLVAALR
Mflv_0403|M.gilvum_PYR-GCK          ----------------EPGSDNLLVVAFINESGLVPEDELTYRNVVDALR
Mvan_0271|M.vanbaalenii_PYR-1       ----------------ETSNDNLLLVAFINETGLEPADEATYRKVVDALR
MAB_0937c|M.abscessus_ATCC_199      ----------------ESSNDDLLLVVFINENGLGKDDADSYRKVVDALR
MAV_1761|M.avium_104                ----------------ESGSDDLLLVALTDEKGLGPADEAVYRRLVDALR
MSMEG_2677|M.smegmatis_MC2_155      ----------------EAGSENVLLVLLTDEHGLGPDDEQVYRTVVGRLR
Mb3853c|M.bovis_AF2122/97           ----------------EAGLQSVAVVVLSDAKGLGAADERSYKELVDALR
Rv3823c|M.tuberculosis_H37Rv        ----------------EAGLQSVAVVVLSDAKGLGAADERSYKELVDALR
MLBr_01231|M.leprae_Br4923          ----------------EVDSENVLIVLLTDDKGLGPADETVYRTLVDRLR
MUL_3688|M.ulcerans_Agy99           ----------------EFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLR
                                                    : .  .  :: : .   *       *  ::  **

MMAR_2342|M.marinum_M               AEKYS----VQDFISNPPLREVLASKDNKAWNLPVMFKTSQDDPATQSAY
TH_2203|M.thermoresistible__bu      AEPNGDIMMMQDFITTPQLREVVASEDGKAWYLPINLAGAWSTPEGGGAF
Mflv_0403|M.gilvum_PYR-GCK          DDVAD-VVSVQDFLGTPQLRQFLTSEDKTTWVLPVSLVGELGTPRAYESF
Mvan_0271|M.vanbaalenii_PYR-1       DDVTD-VVSVQDFVSTPQLRQFLTSEDKTTWVLPVSLEGELGTPRAFDSF
MAB_0937c|M.abscessus_ATCC_199      HDLTN-VVSVQDFIGTPELRKFLTSQDNKTWVLPVGLAGELGTPKAFESY
MAV_1761|M.avium_104                RDTRD-VVMVQDFISAPPLRSAVTSKDRKAWVLPVGIAGELGTPQSYAAF
MSMEG_2677|M.smegmatis_MC2_155      QDGRD-VLWLQEFLGTPQLRETLSSQDRKAWLLPIGLSGDVGSPESYAAY
Mb3853c|M.bovis_AF2122/97           RDTRD-VVMLQDFVTTPPLRELMTSKDNQAWILPVGLPGDLGSTQSKQAY
Rv3823c|M.tuberculosis_H37Rv        RDTRD-VVMLQDFVTTPPLRELMTSKDNQAWILPVGLPGDLGSTQSKQAY
MLBr_01231|M.leprae_Br4923          NDTKD-VVVLQDFLSTPPLHELLVSKDGKAWILPIVLAGELGTSASYQAY
MUL_3688|M.ulcerans_Agy99           QDPEH-IQHIQDFWGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESV
                                     :       :*:*           * *  :  : : :    . .    : 

MMAR_2342|M.marinum_M               KKIKELVKE---ALAGS-------TLTAHYAGAVATVADLVTIGQEDTHI
TH_2203|M.thermoresistible__bu      TRVAEIVRE---ATADA-------PMTVHLTGPAATIADVTAVGQRDIHV
Mflv_0403|M.gilvum_PYR-GCK          NRVADVIRH---EVPDAGTG--GSSLTVHVTGPAATVADLTVAGEQDRLP
Mvan_0271|M.vanbaalenii_PYR-1       NRVSDVVKH---HLGDG-------PLQVYLTGPAATVADLTVAGEQDRLP
MAB_0937c|M.abscessus_ATCC_199      NRVTSLIQH---SIDGS-------PTTVHITGPAATVADLTVAGQQDRLP
MAV_1761|M.avium_104                NRIAGIVKQ---TLEKHENGPAATSLTVSLTGPAATVADLTVAGERDRLP
MSMEG_2677|M.smegmatis_MC2_155      TRVAGIVDH---AVAGS-------TLTAHLTGPAATLADSIEVGLRDQIK
Mb3853c|M.bovis_AF2122/97           ARVADIVEH---QVAGS-------TLTANLTGPAATVADLNLTGQRDRSR
Rv3823c|M.tuberculosis_H37Rv        ARVADIVEH---QVAGS-------TLTANLTGPAATVADLNLTGQRDRSR
MLBr_01231|M.leprae_Br4923          AGVAGIVKQTLESTAGS-------SLKANLTGPASTVADLTDAGARDRTS
MUL_3688|M.ulcerans_Agy99           EAVRDVINR---THEPAG-------VKAYVTGPAALSDDMHLIGNASLAT
                                      :  :: .                  .  :*..:   *    *  .   

MMAR_2342|M.marinum_M               IEIGTAVSVLVILLMVYRNIVTMLVPLATIGLSLATAQGVLSGLSKI-GL
TH_2203|M.thermoresistible__bu      IEIATVVMVLTILLIVYRNVVTMLMPLVTIGVAFVTAQGLVGALAPL-GL
Mflv_0403|M.gilvum_PYR-GCK          IEIAIAVLVLGVLLLVYRNPVTMLLPLLTIGASVLIAQGVVAGYSELTGA
Mvan_0271|M.vanbaalenii_PYR-1       IEIAIAVLVLGVLLLVYRSAVTMLLPLVTIGSSLVIAQAVVAGYSQLSGS
MAB_0937c|M.abscessus_ATCC_199      IEIAIAVLVLAVLLLVYRSALTMMLPLVTIGSSLVIAQSVVAAYSQLTGA
MAV_1761|M.avium_104                IELAIAVLVLVVLLVVYRSAVTMLLPLVTILLSLVIAQAAVAGYSQLTGS
MSMEG_2677|M.smegmatis_MC2_155      IEIAIVALLLTILVIVYRKPATILLPVLMIGVSLGVAQAVVAGAAQL-GL
Mb3853c|M.bovis_AF2122/97           IEFAITILLLVILLIIYRNPITMVLPLITIGMSVVVAQRLVA-IAGLAGL
Rv3823c|M.tuberculosis_H37Rv        IEFAITILLLVILLIIYGNPITMVLPLITIGMSVVVAQRLVA-IAGLAGL
MLBr_01231|M.leprae_Br4923          IELVIAVLLLTILMIIYRNPITMLLPLITIGASLMTAQAVVSGVSVLAGL
MUL_3688|M.ulcerans_Agy99           ITMFTLGAIAVMLLLVYRSIVTTVIQLFMTGIALASSRGVVAVLGYHNVF
                                    * :     :  :*:::* .  * :: :     :.  ::  :.  .     

MMAR_2342|M.marinum_M               DVQMQTIVFMTAVMIGAGTDYAVFLISRYHDYVRKGQDSDL----AVKNA
TH_2203|M.thermoresistible__bu      GVSDQTIVLMTGIMVGAGVDYAVFLISRYHDFVRRGVEHRA----AIRQA
Mflv_0403|M.gilvum_PYR-GCK          GVSNQSIVFLSAILAGAGTDYAVFLISRYHDYLRRGAEAGE----AVRAA
Mvan_0271|M.vanbaalenii_PYR-1       GVSNQSIVFLSAIMAGAGTDYAVFLISRYHDYLRSGADFDD----AVRAA
MAB_0937c|M.abscessus_ATCC_199      GVSNQSIVFLSAILAGAGTDYAVFLISRYHDYLRSGKNYDQ----AVRAA
MAV_1761|M.avium_104                GVSNQSIVFLSAIMAGAGTDYAVFLISRYHDFLRRGDDFDQ----AVRKA
MSMEG_2677|M.smegmatis_MC2_155      GVSNQTITLLSGLMAGAGTDYAVFLISRYHDFLRLGADSDQ----AVKSA
Mb3853c|M.bovis_AF2122/97           GIANQSIIFMSGMMVGAGTDYAVFLISRYHDYLRQGADSDQ----AVKKA
Rv3823c|M.tuberculosis_H37Rv        GIANQSIIFMSGMMVGAGTDYAVFLISRYHDYLRQGADSDQ----AVKKA
MLBr_01231|M.leprae_Br4923          AVSNQMIVLLSAMIAGAGTDYAVFLISRYHDYIRMGSGSAQDAGCAVRQA
MUL_3688|M.ulcerans_Agy99           GLTTFAANILTMLAIAAGTDYGIFLVGRYQEARQAGEDRQD----AYYTT
                                     :      ::: :  .**.**.:**:.**::  : *         *   :

MMAR_2342|M.marinum_M               MMSIGKVIAASAATVAVTFLAMVFSKLAIFASIGPAISISIIIAFVAAIT
TH_2203|M.thermoresistible__bu      MGSIGKVIGASAATVAVTFFAMVFTTLSVFQTVGPAMALAIFVCFLAAVT
Mflv_0403|M.gilvum_PYR-GCK          MASIGKVITASASTVGITFLAMSFAEMGVFRTIGVSAAIGIGVAYLAGVT
Mvan_0271|M.vanbaalenii_PYR-1       MISIGKVITASAATVGVTFLVMSFAQMGVFRTIGVSSAIGIGVAFLAGMT
MAB_0937c|M.abscessus_ATCC_199      MMSIGKVITASATTVGITFLLLSFAKMGVFQTVGVSSAIGIGVAYLSGMT
MAV_1761|M.avium_104                LISIGKVITASASTVGITFLLIGFARMGVFKTVGISSAIGIGVAFLAAVT
MSMEG_2677|M.smegmatis_MC2_155      LSSIGKVIAASAATVGVTFLGMTFASLELFATIGPALAIAIGVAFLAAVT
Mb3853c|M.bovis_AF2122/97           LTSIGKVIAASAATVAITFLGMVFTQLGILKTVGPMLGISVAVVFFAAVT
Rv3823c|M.tuberculosis_H37Rv        LTSIGKVIAASAATVAITFLGMVFTQLGILKTVGPMLGISVAVVFFAAVT
MLBr_01231|M.leprae_Br4923          LISLGKVIAASAATVGITFLGMSFTKIRVFSTVGPALAIGIAVAFLAAVT
MUL_3688|M.ulcerans_Agy99           FRGVAPVVLGSGLTIAGATYCLSFARLPWFNTMGAPVAIGMLVVVLAGLT
                                    : .:. *: .*. *:. :   : *: :  : ::*   .:.: :  .:.:*

MMAR_2342|M.marinum_M               LLPSILVLIGRRGWIKPRRDL-THRFWRILGTRIVRRPRVHLIGSLIVLA
TH_2203|M.thermoresistible__bu      FLPAMIVLAGPRGWISPRRDL-TTRFWRRSGIRIVRAPKAHLAVSLIILL
Mflv_0403|M.gilvum_PYR-GCK          LLPAILVLAGPRGWIKPRREL-TAQFWRRSGIRIVRRPVPHLVASALVLA
Mvan_0271|M.vanbaalenii_PYR-1       LLPAILVLAGPRGWVKPRREL-TARFWRRSGIRIVRRPVPHLVASVLVLI
MAB_0937c|M.abscessus_ATCC_199      LLPAILVLAGPRGWVKPRREL-TAQFWRRSGIRIVRRPIPHLVASVLVLA
MAV_1761|M.avium_104                LLPAIMVLAGPRGWIRPRREL-TTGLWRRSGIRIVRRPRAHLVASVLVLI
MSMEG_2677|M.smegmatis_MC2_155      LLPAIIVLAGRRGWVSPRREI-TARFWRRSGIRIVRRPVTNLVASLMVLL
Mb3853c|M.bovis_AF2122/97           LLPALMVLTGRRGWIAPRRDL-TRRFWRSSGVHIVRRPKTHLLASALVLV
Rv3823c|M.tuberculosis_H37Rv        LLPALMVLTGRRGWIAPRRDL-TRRFWRSSGVHIVRRPKTHLLASALVLV
MLBr_01231|M.leprae_Br4923          LMPALLVLAGTRGWVAPRRDR-AGAFWRRTGVRIVRRPVAYLSASMVILI
MUL_3688|M.ulcerans_Agy99           LGPAVVFVGSRFHPFESKRAANRGRLWRRVGTAVVRWPAPILALSGAIVL
                                    : *:::.: .    . .:*      :**  *  :** *   *  *  :: 

MMAR_2342|M.marinum_M               ILASSTLLVRFNYDDLKALPEDVDSVAGYNAMDRHFPQNMMTPMMLFIKS
TH_2203|M.thermoresistible__bu      GLAGCALTVQFNYDDRKTLPQSVESAAGYAAMERHYPVNSNLPQYLFINS
Mflv_0403|M.gilvum_PYR-GCK          LLAGFAIVADFNYDDRKAVDAAAPSSVGYAALERHFPISQSIPQYILIQS
Mvan_0271|M.vanbaalenii_PYR-1       LLAGCAAFATFNYDDRKAVAASAPSSVGYAALERHFPISQSIPQYILVQS
MAB_0937c|M.abscessus_ATCC_199      LLGSCALLARYNYDDRKAVSPSAPSSVGYAALERHFPLSQSIPEYILIQS
MAV_1761|M.avium_104                ILASCAGLVRYNYDDRKALRPSAPSSVGYAALERHFPVNQSIPEYILIRS
MSMEG_2677|M.smegmatis_MC2_155      VRD----------------------------------------------P
Mb3853c|M.bovis_AF2122/97           ILAGCAGLARYNYDDRKTLPASVESSIGYAALDKHFPSNLIIPEYLFIQS
Rv3823c|M.tuberculosis_H37Rv        ILAGCAGLARYNYDDRKTLPASVESSIGYAALDKHFPSNLIIPEYLFIQS
MLBr_01231|M.leprae_Br4923          VLALCASLVRFNYDDRKQIPASDESSVGYAALESHFPVGQAIPEYLLIQS
MUL_3688|M.ulcerans_Agy99           VGMVALPGFKTSYNDRYYLPASAPSNLGEAAADRHFSHARMNPDMLMVEA
                                                                                     .

MMAR_2342|M.marinum_M               PHDLRSPTALADLELMVSRVSQLPNIIAIRGLTRPNGEPLEQTKVSYQAG
TH_2203|M.thermoresistible__bu      PRDLRSPEALADLEEMARRVSQLPEVDTVRGITRPTGEPLEQAALSYQAG
Mflv_0403|M.gilvum_PYR-GCK          PKDLRNPQALADLEQMASRIAQLPDVSLVSGVTRPLGEVPAEFRATFQAG
Mvan_0271|M.vanbaalenii_PYR-1       PRDLRSPQALADLEQMASRIAQLPDISLVSGVTRPLGEVPREFRATFQAG
MAB_0937c|M.abscessus_ATCC_199      PRDLRTPQALADLEQMASRIAQLPDVGLVSGVTRPLGEVPPEFRATYQAG
MAV_1761|M.avium_104                PHDLRTPQALADLEQLADRVSQLPNVSVVSGITRPTGNVPEQFRATYQAG
MSMEG_2677|M.smegmatis_MC2_155      PRRVWRVLPLG-----------------------RMGTWDRSHRGGIQTS
Mb3853c|M.bovis_AF2122/97           STDLRTPKALADLEQMVQRVSQVPGVAMVRGITRPAGRSLEQARTSWQAG
Rv3823c|M.tuberculosis_H37Rv        STDLRTPKALADLEQMVQRVSQVPGVAMVRGITRPAGRSLEQARTSWQAG
MLBr_01231|M.leprae_Br4923          PHDLRTPRALADMAELAQRVSQIPGIALVRGVTRPTGKPLEETSATYQAG
MUL_3688|M.ulcerans_Agy99           EHDMRNPADMLVLDKVAKNVIRTVGIAMIQDITRPLGIPIQHSSIPFQNS
                                       :     :                          *          * .

MMAR_2342|M.marinum_M               EVGSKLDEASSAIEDHGGELDQLADGSNQLADALAGVRDEVTESVANAGA
TH_2203|M.thermoresistible__bu      EVGIRLDDASKQITDHTGDLDMLADGADQLADALGDVRGQVFQTVATTKA
Mflv_0403|M.gilvum_PYR-GCK          IVGDRLAAGSAQIGERSGDLTTLADGATTLADSLGDVRSQVNEIAPSLKG
Mvan_0271|M.vanbaalenii_PYR-1       LVGDRLAAGSAQIGARDDDLDELTTGADTLADTLVDVRAQVNKIAPSLQT
MAB_0937c|M.abscessus_ATCC_199      LVGTRLADGSNQINQRSSDLNRLTSGANTLAGSLTDLRNQLNKITPGLQS
MAV_1761|M.avium_104                AIGSMLAGGSTMINDQTDDLNRLARGAGTLADNLGDVRGQVNQLAASVRE
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           EVGSKLDEGSKQIAAHTGDIDKLAGGANLMASKLGDVRAQVNRAISTVGG
Rv3823c|M.tuberculosis_H37Rv        EVGSKLDEGSKQIAVHTGDIDKLAGGANLMASKLGDVRAQVNRAISTVGG
MLBr_01231|M.leprae_Br4923          MVGKQLGSASHLIGESTGDLNRLASGAGLLADKLGDVRIQVGQAVAGISG
MUL_3688|M.ulcerans_Agy99           MQSQTMMQNMAFLKERMADMTKMADEMQVLIDTTERMYAVMRELDTTTTD
                                                                                      

MMAR_2342|M.marinum_M               LVDLLVTMKKLIGGDKTLNALDQTAKLVGRMRALGDALTSNMVDVSNVVA
TH_2203|M.thermoresistible__bu      LVDALSTLQERFGGDRTLDDIDNAARLVSGMRELGDAIGVNVANVAGNLE
Mflv_0403|M.gilvum_PYR-GCK          IIDTFSSVRTEYGGDKLVRDVATAAKLVDSVNKLGLSMGINFRAVRDMFA
Mvan_0271|M.vanbaalenii_PYR-1       LLDAVTRVRVEYGGDRLVRDVETAAKLVQSVNELGLSMGISFAAVRDMFG
MAB_0937c|M.abscessus_ATCC_199      LLEASNSLKTKSGGDELVRNVDNAAKLVDEINALANDMGWNFSAAKDMFG
MAV_1761|M.avium_104                LENAFSSTKNQYSGDALVNQVDIAARLVDHVNSLSNAMGWNFTAAKNMFA
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           LIDALAYLQDLLGGNRVLGELEGAEKLIGSMRALGDTIDADASFVANNTE
Rv3823c|M.tuberculosis_H37Rv        LIDALAYLQDLLGGNRVLGELEGAEKLIGSMRALGDTIDADASFVANNTE
MLBr_01231|M.leprae_Br4923          LLDNLAFAQKMFGDSKTLGEIDTAGKLVSSMRALGNMFGINFSTTMNDIN
MUL_3688|M.ulcerans_Agy99           MARVTAETSTITDELR--------------------------DHLAEFDD
                                                                                      

MMAR_2342|M.marinum_M               WVGPIVSALNASPQCNADPACAAARSQLQALVAAQTSGSLSSITALGRTL
TH_2203|M.thermoresistible__bu      WAVPVLTALDTSPVCAADPRCVSAREELRQLTVAGRQGVLDRIAALGRQL
Mflv_0403|M.gilvum_PYR-GCK          WIGPVLTALQGNRVCDANPSCVDTRMQFEKLVSAREDGRVDEINQLAGQL
Mvan_0271|M.vanbaalenii_PYR-1       WIGPVLAALHGNAVCDANPSCVNTRMQFERLMDARADGRLERINTLAGEL
MAB_0937c|M.abscessus_ATCC_199      WINPVLAALQGNPICDADTSCSNTRGQFERLVGERNSGRLDEIERLAHQL
MAV_1761|M.avium_104                WIGPVLAALQGNPVCDADSSCSATRATFEQLVGPRGQADLDAIDDLSHQL
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           WASPVLGALDSSPMCTADPACASARTELQRLVTARDDGTLAKISELARQL
Rv3823c|M.tuberculosis_H37Rv        WASPVLGALDSSPMCTADPACASARTELQRLVTARDDGTLAKISELARQL
MLBr_01231|M.leprae_Br4923          WVGAVVIALDSSVLCDTNPICADARAQFHKLLTASEDGTLDNIAHLWKQL
MUL_3688|M.ulcerans_Agy99           FWRPMRSYFYWEKHCFDVPICWSFRSLFDSLDG------IDKLSEKFSEL
                                                                                      

MMAR_2342|M.marinum_M               QQ-TQEFQTVAQTIAKLETNLNQAVKLLRSIDG-----MQNQLNQMQQGA
TH_2203|M.thermoresistible__bu      EE-TRGGQTIDQTLATLTGTLTDATAALRAAGLDKPGSLQAKIATMQEGA
Mflv_0403|M.gilvum_PYR-GCK          QG-VDDRQSLTATVNQLNGALAQVTKAISAMGLDTPAGARAGLDDLQDGA
Mvan_0271|M.vanbaalenii_PYR-1       EG-LDDTQSLNSTVKTLNAAMTNIVKAVDELGLDSPGGAQTSLRDIRQGT
MAB_0937c|M.abscessus_ATCC_199      GNSPGNKATLSTTVTKLNASLLSVVNGLHAMGLDKPGGPQAGLNQLRQGA
MAV_1761|M.avium_104                QAYPDKR-ALKASTDRLRNAFAKLNDVLRAMGMDRPGGLQSNLTTLQNGA
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           QA-TRAVQTLAATVSGLRGALATVIRAMGSLGMSSPGGVRSKINLVNKGV
Rv3823c|M.tuberculosis_H37Rv        QA-TRAVQTLAATVSGLRGALATVIRAMGSLGMSSPGGVRSKINLVNKGV
MLBr_01231|M.leprae_Br4923          GS-TQSSQTIGATVSGLEKTLTAVNTSLRSLGLDNPNVMRSKMIGLQNGV
MUL_3688|M.ulcerans_Agy99           TEDIQRTAGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELS
                                                                                      

MMAR_2342|M.marinum_M               SALAQGSRAIAQGVNELVKQTKRMGTGLDEASDFLLQMKHDANKPSMAGF
TH_2203|M.thermoresistible__bu      DALADASRKLADGVQLLVNQTKEMGSGLGEASSFLLAMKRDATTPAMAGF
Mflv_0403|M.gilvum_PYR-GCK          DRLADGSRQVAGGVDQLVEQIKVMAAGLDQAAAFLLTMRNDASSSNMAGF
Mvan_0271|M.vanbaalenii_PYR-1       DRLASGSRQVAGGVDQLVEQVRVMADGLNQAAAFLLTMRHDAASANMAGF
MAB_0937c|M.abscessus_ATCC_199      DRLAGGSQQVAGGVDQLVGQIKVIVNGLNQASNFLLTMKTNAADPSQAGF
MAV_1761|M.avium_104                DQFAGGSRQVADAVAQLVDKVKQLGAGLSESAAFLLSLKHDAAHPAMAGF
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           NDLADGSRQLAEGVQLLVDQVKKMGFGLGEASAFLLAMKDTATTPAMAGF
Rv3823c|M.tuberculosis_H37Rv        NDLADGSRQLAEGVQLLVDQVKKMGFGLGEASAFLLAMKDTATTPAMAGF
MLBr_01231|M.leprae_Br4923          NDLASAGRRIADGVAVLVDQTRTMGTSLARASAFLMEMGQDASQPSMAGF
MUL_3688|M.ulcerans_Agy99           N------------------------------TAIVMGQSFDASKND-DFF
                                                                                      

MMAR_2342|M.marinum_M               NIPPEAL------------------------AKDEFKKAAQIFISPDGHG
TH_2203|M.thermoresistible__bu      YIPPEVL------------------------TQEEFAKAAEIFVSPDGHG
Mflv_0403|M.gilvum_PYR-GCK          SIPAEVL------------------------GAVEFQKASEAFVSPDGHS
Mvan_0271|M.vanbaalenii_PYR-1       SIPAEVL------------------------NAVEFQKAAEAFISPDGHS
MAB_0937c|M.abscessus_ATCC_199      NIPAEVL------------------------NNPDFQRAAKAFISPDGHS
MAV_1761|M.avium_104                NIPAQLL------------------------RLPQFQEAAKVFISPDGHS
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           YIPPELLSYATGESVKAETMPSEYRDLLGGLNVDQLKKVAAAFISPDGHS
Rv3823c|M.tuberculosis_H37Rv        YIPPELLSYATGESVKAETMPSEYRDLLGGLNVDQLKKVAAAFISPDGHS
MLBr_01231|M.leprae_Br4923          NVPPQLL------------------------NTEDFKKLVQAFISPDGHS
MUL_3688|M.ulcerans_Agy99           YLPPEAFD------------------------NPDFQTGLRMFLSPDGKS
                                                                                      

MMAR_2342|M.marinum_M               ARYLVQSALNPFTTAAMDQVDEILDVAHDAQPNSELSDATISMVGIPTGL
TH_2203|M.thermoresistible__bu      VRYLVTTTLNPFSTEAMDLVNEITETARGARANTELAEADISMAGFTTTL
Mflv_0403|M.gilvum_PYR-GCK          VRYLVQTKLNPFSSEAMDQVNTISDIARGAQPNTMLSDASISMGGFPAAL
Mvan_0271|M.vanbaalenii_PYR-1       VRYLVQTRLNPFSPEAMDQVNVINDIARGAQPNTSLADASISMGGFPAAL
MAB_0937c|M.abscessus_ATCC_199      VRYLVQTKLNPFSPEAMDQVNQISDVAKGAQPNTTLADATISMGGFPTAL
MAV_1761|M.avium_104                VRYLVQSKLSPFSTQAMDQVDAITATARGAQPNTALADAEVSMAGYTVGL
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           IRYLIQTDLNPFSTAAMDQIDAITAAARGAQPNTALADAKVSVVGLPVVL
Rv3823c|M.tuberculosis_H37Rv        IRYLIQTDLNPFSTAAMDQIDAITAAARGAQPNTALADAKVSVVGLPVVL
MLBr_01231|M.leprae_Br4923          VRYFIQTDLNPFSSAAMDQVNTILNVATGAQPNTTLSDASIYLSGYTVTL
MUL_3688|M.ulcerans_Agy99           ARFFITHQGDPMTPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATF
                                                                                      

MMAR_2342|M.marinum_M               SDTRDYYNHDIQFIVFATILIVFLILVILLRAIVAPLYLIGSVLVSFLSA
TH_2203|M.thermoresistible__bu      RDTRDYYNNDFRLITTLTVVIVFLILVALLRAIVAPLYLIASVVISYLSA
Mflv_0403|M.gilvum_PYR-GCK          RDTRDYYERDIRFIIVVTLVIVMLVLMLLLRSLIAPLYLVGSVVVSYFAA
Mvan_0271|M.vanbaalenii_PYR-1       RDTRDYYERDIRFIIIAALIVVLVTLSVLLRSLVAPLYLVGSVVVSYFAA
MAB_0937c|M.abscessus_ATCC_199      RDTRDYYQHDIQFIIAATLIVVLLTLMVLLRAIVAPLYLVGSVVLSYFAA
MAV_1761|M.avium_104                KDTRDYYQHDIKFIIAVTLLVVLLTLMALLRAIVAPLYLVATVVISYLSA
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           KDTRDYSDHDLRLIIAMTVCIVLLILIVLLRAIVAPLYLIGSVIVSYLAA
Rv3823c|M.tuberculosis_H37Rv        KDTRDYSDHDLRLIIAMTVCIVLLILIVLLRAIVAPLYLIGSVIVSYLAA
MLBr_01231|M.leprae_Br4923          RDTRDYYDRDLQLIVIVTMIVVLLILMALLRSIVAPIYLVGSVIVSYLSA
MUL_3688|M.ulcerans_Agy99           KDMADGEKYDLMIAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAAS
                                                                                      

MMAR_2342|M.marinum_M               LGLGVIVFQLILGKDLHWSLPGLSFILLVAVGADYNMLLISRIRDESPHG
TH_2203|M.thermoresistible__bu      LGLGVILFQYILGQELSWSVPGLTFIVLVAVGADYNMLLISRIREESPHG
Mflv_0403|M.gilvum_PYR-GCK          IGIGVLVFQLLLGQQLHWSVPPLAFVVLVAVGADYNMLFVSRMRDESPHS
Mvan_0271|M.vanbaalenii_PYR-1       IGIGVLTFQLLLGQQLHWSVPPLAFVVLVAVGADYNMLFVSRLRDESPHS
MAB_0937c|M.abscessus_ATCC_199      IGIGVLTFQYLLGEQLHWTVPPLAFVVLVAVGADYNMLFVSRMRDESASS
MAV_1761|M.avium_104                VGVGVLVFQFLLGQQLHWSVPPLAFVVLVAVGADYNMLLVSRMRDESPHS
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           LGIGVIVFQFLLGQEMHWSIPGLTFVILVAVGADYNMLLISRLREEAVLG
Rv3823c|M.tuberculosis_H37Rv        LGIGVIVFQFLLGQEMHWSIPGLTFVILVAVGADYNMLLISRLREEAVLG
MLBr_01231|M.leprae_Br4923          LGLCVLVFQVLLRQQLHWSVPGLAFVVLVAVGADYNMLLASRLRDESSHG
MUL_3688|M.ulcerans_Agy99           FGLSVLIWQDLFGIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAG
                                                                                      

MMAR_2342|M.marinum_M               VRVGVIRTVGSTGGVITSAGLIFAASMFGLLAASITTMVEAGFIIGSGIL
TH_2203|M.thermoresistible__bu      IRSGIIRTVGHTGGVITSAGLIFAASMFGLVFASITTMIQAGFILGVGLL
Mflv_0403|M.gilvum_PYR-GCK          VRFGIIRTLGSTGGVITAAGLIFAASMAGLLFSSIGIVVQGGFVIGVGIL
Mvan_0271|M.vanbaalenii_PYR-1       VRYGVIRTLGSTGGVITAAGLIFAASMAGLLFSSIGIVVQGGFVIGVGIL
MAB_0937c|M.abscessus_ATCC_199      VRYGIIRALNSTGGVITAAGLIFAASVGGLLFSSIGIVVQGGFVIGVGIL
MAV_1761|M.avium_104                MRYGIIRTLSSTGGVITAAGLIFAASMSGLLFSSIGTVVQGGVVIGVGIL
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           VRSGVIRTVASTGGVITAAGLIMAASMYGLVFASLGSVVQGAFVLGTGLL
Rv3823c|M.tuberculosis_H37Rv        VRSGVIRTVASTGGVITAAGLIMAASMYGLVFASLGSVVQGAFVLGTGLL
MLBr_01231|M.leprae_Br4923          LRASVIRTVRSTGGVITAAGLIFAASMFGLLLSSIATVVQAGFVLGSGIL
MUL_3688|M.ulcerans_Agy99           LKTGIIRSMAGTGGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLL
                                                                                      

MMAR_2342|M.marinum_M               IDTFLVRSVTVPAMAAMLGQANWWPSKIGASSTRRRVYQRAGSRKPNLLD
TH_2203|M.thermoresistible__bu      LDTFLVRTITVPATAVLVGRANWWPAKPPHDG------------------
Mflv_0403|M.gilvum_PYR-GCK          LDTFVVRTITVPAIATLLGRANWWPSRVA---APARERVSADT-------
Mvan_0271|M.vanbaalenii_PYR-1       LDTFVVRTITVPAIAALVGRANWWPSKVGPQQAAPRAVESAGSG------
MAB_0937c|M.abscessus_ATCC_199      LDTFVVRTITVPAIAALVGKANWWPSQVNARQTSSAKPSAAAPAG-----
MAV_1761|M.avium_104                LDTFLVRTVTVPAIAALAGRANWWPSRIAVR----RNPVSGQP-------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           LDTFLVRTVTVPAIAVLVGQANWWLPSSWRPATWWPLGRRRGRAQRTKRK
Rv3823c|M.tuberculosis_H37Rv        LDTFLVRTVTVPAIAVLVGQANWWLPSSWRPATWWPLGRRRGRAQRTKRK
MLBr_01231|M.leprae_Br4923          LDTFIVRTITVPAVAALLRRASWWPARPWGNNA-----------------
MUL_3688|M.ulcerans_Agy99           LDTLIVRTLLMPSIATLLGRWFWWPQVVHPRGDNARPRVAAPTH------
                                                                                      

MMAR_2342|M.marinum_M               RIKSLGPAKQRAAVTAKASTTTTKRPSTAVKKRGELVSKPGTRKRVRKPA
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           PLLPKEEEEQSPPDDDDLIGLWLHDGLRL---------------------
Rv3823c|M.tuberculosis_H37Rv        PLLPKEEEEQSPPDDDDLIGLWLHDGLRL---------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               WPDIPITNDDYESLQEHALPLFGSIRLPRELTPIDPALHNGDGATSNGDG
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           --------------------------------------------------
Rv3823c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               TTNGSGADCKQLQLIGLGDTTEFRVPNGTTNGNGNGNGHTNGNGHTNGNG
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           --------------------------------------------------
Rv3823c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               HTNGNGHTNGTNGHGTNGATNGNGHTNGTNGTNGHGTNGATNGHTNGTNG
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           --------------------------------------------------
Rv3823c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               NGHTNGTNGHGTNGATNGNGHTNGTNGTNGHGTNGATNGHTNGNGNGTNG
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           --------------------------------------------------
Rv3823c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               NGNGTNGHGTNGHTNGNGTNGATNGASNGATNGTNGHTNGNGNGNGTNGH
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           --------------------------------------------------
Rv3823c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               TSGNGNGTNGATNGASNGATNGTNGHTNGNGNGTNGATNGHTNGNGNGTN
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           --------------------------------------------------
Rv3823c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               GHTSGNGNGTNGATNGASNGATNGTNGHTNGNGNGNGTNGATNEHGTNGS
TH_2203|M.thermoresistible__bu      --------------------------------------------------
Mflv_0403|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0271|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0937c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_1761|M.avium_104                --------------------------------------------------
MSMEG_2677|M.smegmatis_MC2_155      --------------------------------------------------
Mb3853c|M.bovis_AF2122/97           --------------------------------------------------
Rv3823c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01231|M.leprae_Br4923          --------------------------------------------------
MUL_3688|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MMAR_2342|M.marinum_M               TNGDIDDADEGHALPLFGPSNQRDLLIKR
TH_2203|M.thermoresistible__bu      -----------------------------
Mflv_0403|M.gilvum_PYR-GCK          -----------------------------
Mvan_0271|M.vanbaalenii_PYR-1       -----------------------------
MAB_0937c|M.abscessus_ATCC_199      -----------------------------
MAV_1761|M.avium_104                -----------------------------
MSMEG_2677|M.smegmatis_MC2_155      -----------------------------
Mb3853c|M.bovis_AF2122/97           -----------------------------
Rv3823c|M.tuberculosis_H37Rv        -----------------------------
MLBr_01231|M.leprae_Br4923          -----------------------------
MUL_3688|M.ulcerans_Agy99           -----------------------------