For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_2601 (pcaH)

annotation: protocatechuate 3,4-dioxygenase, beta subunit
coordinates: 2683715 - 2684461
length: 248

MALVSQSDISAEINEITESYHRGGLDEAQPRLDYPPYRSSVLRHPKAQLHQTDPESIELWAPCFGERDVA
EHESDLTIQHTAEPIGERIVVTGRVVDGDGRPVRHQLVEIWQANAAGRYRHLRDQHPAPLDPNFTGVGRC
LTDADGTYRFTTIKPGPYPWRNHHNAWRPAHIHFSLFGTEFTQRMITQMYFPGDPLFAFDPIYQSITDAK
ARERLVATYDHDVTTHEWATGYRWDIVLTGSLRTPTEA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2601pcaH-100% (248)protocatechuate 3,4-dioxygenase, beta subunit
M. smegmatis MC2 155MSMEG_1911catA5e-1231.65% (139) catechol 1,2-dioxygenase
M. smegmatis MC2 155MSMEG_2602pcaG9e-1233.33% (156) protocatechuate 3,4-dioxygenase, alpha subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0530-1e-11775.20% (246) protocatechuate 3,4-dioxygenase, beta subunit
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_3506pcaH1e-10369.92% (246) protocatechuate 3,4-dioxygenase, beta subunit
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0560-1e-11775.20% (246) protocatechuate 3,4-dioxygenase, beta subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0530|M.gilvum_PYR-GCK          MPLVEGAENVQQTRGDSGSRRRSVPCQLWMAFPLSGILPFASLNVVGTVG
Mvan_0560|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2601|M.smegmatis_MC2_155      --------------------------------------------------
MAV_3506|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_0530|M.gilvum_PYR-GCK          AVTTLIDSNPDGAVASQSEISAEIGAIESAYQRAGVEETQPRLSYPPYRS
Mvan_0560|M.vanbaalenii_PYR-1       -MTTLIDSNPDGAVASQSEISAEIGAIESAYQRAGVEETQPRLSYPPYRS
MSMEG_2601|M.smegmatis_MC2_155      -----------MALVSQSDISAEINEITESYHRGGLDEAQPRLDYPPYRS
MAV_3506|M.avium_104                --------MDPECVASQGDITAEIARIAAQYRADDGGAGQPLLDYPPYRA
                                                .:.**.:*:***  *   *:  .    ** *.*****:

Mflv_0530|M.gilvum_PYR-GCK          SLLRHPTKDLHHADPEGVELWTPCFSERDVHPLEADLTVQHSGEPIGERL
Mvan_0560|M.vanbaalenii_PYR-1       SLLRHPTKDLHHADPEGVELWTPCFSERDVHPLEADLTVQHSGEPIGERL
MSMEG_2601|M.smegmatis_MC2_155      SVLRHPKAQLHQTDPESIELWAPCFGERDVAEHESDLTIQHTAEPIGERI
MAV_3506|M.avium_104                TILRHPKQPLVAVDPEAAELWAPCFGRDDVDPLDADLTAGHRGEPIGERV
                                    ::****.  *  .***. ***:***.. **   ::***  * .******:

Mflv_0530|M.gilvum_PYR-GCK          VVTGRVVDGAGRPVRRQLVEIWQANAGGRYIHKGDQHPSPIDPNFTGAGR
Mvan_0560|M.vanbaalenii_PYR-1       VVTGRVVDGAGRPVRRQLVEIWQANAGGRYIHKRDQHPSPIDPNFTGAGR
MSMEG_2601|M.smegmatis_MC2_155      VVTGRVVDGDGRPVRHQLVEIWQANAAGRYRHLRDQHPAPLDPNFTGVGR
MAV_3506|M.avium_104                VVAGRVVDEAGRPVAGQLVEIWQANAAGRYRHQRDRHPAPLDPNFTGAGR
                                    **:*****  ****  **********.*** *  *:**:*:******.**

Mflv_0530|M.gilvum_PYR-GCK          CLTDEDGIYRFTTIKPGPYPWKNHRNAWRPAHIHFSLFGTEFTQRMVTQM
Mvan_0560|M.vanbaalenii_PYR-1       CLTDEDGIYRFTTIKPGPYPWKNHRNAWRPAHIHFSFFGTEFTQRMVTQM
MSMEG_2601|M.smegmatis_MC2_155      CLTDADGTYRFTTIKPGPYPWRNHHNAWRPAHIHFSLFGTEFTQRMITQM
MAV_3506|M.avium_104                CLTGPDGWYRFLTIKPGPYPWRNHHNAWRPAYIHFSVFGTAFTQRLITQM
                                    ***. ** *** *********:**:******:****.*** ****::***

Mflv_0530|M.gilvum_PYR-GCK          YFPGDPLLCLDPIFQAIPDQKARSRLVASYDHELSTHEWATGYRWDVVLT
Mvan_0560|M.vanbaalenii_PYR-1       YFPGDPLLCLDPIFQAIPDQKARSRLVASYDHELSTHEWATGYRWDVVLT
MSMEG_2601|M.smegmatis_MC2_155      YFPGDPLFAFDPIYQSITDAKARERLVATYDHDVTTHEWATGYRWDIVLT
MAV_3506|M.avium_104                YFPGDPMFELDPIFQSILDPAARRRLIAHYDHDLTQPEYATGYRWDIVLA
                                    ******:: :***:*:* *  ** **:* ***:::  *:*******:**:

Mflv_0530|M.gilvum_PYR-GCK          GSARTPIENLGRGAHR
Mvan_0560|M.vanbaalenii_PYR-1       GSARTPIENLGRGAHR
MSMEG_2601|M.smegmatis_MC2_155      GSLRTPTEA-------
MAV_3506|M.avium_104                GGGRTPTGAGND----
                                    *. ***