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NEMTELLRESRMGALGTESHAREVRQISLADFGSRFDEIADELWAAATDIGFFQVVEHGIDLAEVDRVFD VAQRFFALPTAVKEKYPLKRGQNAGWEYKSQIRPSVGTADEKESYQFTRPRMDGLWPAPDELDGFRDTIE DFERRCWRLAMDILSCFAVRLGFDREFFARAHDPDAPTYQSTLRLLHYYAFPAELVGRDDVWRAGAHTDF DALTLLFQRSGQPGLQVLPGAEADQQVWTPVHPSDDVITCNIGDMLMRWSDDLLPSNFHRVRAPRPGESL DPRYSVAYFAQANTDVLIESPKGTYPPITAAEYLRRRIAANFG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2569 | - | - | 100% (324) | oxidoreductase, 2OG-Fe(II) oxygenase family protein |
| M. smegmatis MC2 155 | MSMEG_4685 | - | 3e-28 | 30.55% (311) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4008 | - | 2e-22 | 29.80% (302) | oxidoreductase, 2OG-Fe(II) oxygenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2580 | - | 6e-25 | 30.94% (307) | 2OG-Fe(II) oxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4434c | - | 4e-14 | 25.42% (295) | putative iron/ascorbate dependent oxidoreductase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4913 | - | 2e-18 | 30.34% (290) | oxidoreductase, 2OG-Fe(II) oxygenase family protein |
| M. thermoresistible (build 8) | TH_4524 | - | 2e-27 | 34.09% (308) | PUTATIVE 2OG-Fe(II) oxygenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4054 | - | 3e-25 | 29.26% (311) | 2OG-Fe(II) oxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2580|M.gilvum_PYR-GCK ------------------MSVIATVDLSRWREGGPAAEDVAAQVDAGLQR
Mvan_4054|M.vanbaalenii_PYR-1 ------------------MSVIATVDLSRWRAGGAAADAVAADVDEGLQR
MAB_4434c|M.abscessus_ATCC_199 -------MAVKTVAPKRLASNHGRVAELPVIDLSSDSNQLRAALREVAHE
MAV_4913|M.avium_104 -------------MSNDMCPVPG-VTAVPGVDLRADPDVLRDGLREAAHR
TH_4524|M.thermoresistible__bu -------------MAGDFTSVPVIDISALRHGSGPGYRRAVTALGDAARH
MSMEG_2569|M.smegmatis_MC2_155 MNEMTELLRESRMGALGTESHAREVRQISLADFGSRFDEIADELWAAATD
. . :
Mflv_2580|M.gilvum_PYR-GCK AGFILVTGHGVDPDLARDVRAAAREFFALDPTVKAGYSVPVGGRGWIGPG
Mvan_4054|M.vanbaalenii_PYR-1 AGFILVSGHGVSASLARDVRAAAREFFALPDEVKSGYSVPVGGHGWIGPG
MAB_4434c|M.abscessus_ATCC_199 VGFFYLTGHGVSPQLVHEVLSAARKLFALSEADKEAIAMVRSPH-FRGFT
MAV_4913|M.avium_104 VGFFYLTGHGVPADLVDRVLDAARRFFRLPQADKDAVAMVRSPH-FRGYT
TH_4524|M.thermoresistible__bu VGFAQLVGHGIDPALFDALVDRTRAFFALPAAEKHRVYIGNSTN-HRGYV
MSMEG_2569|M.smegmatis_MC2_155 IGFFQVVEHGIDLAEVDRVFDVAQRFFALPTAVKEKYPLKRGQN--AGWE
** : **: : :: :* * * : . . *
Mflv_2580|M.gilvum_PYR-GCK AEANGYAEGTETPPDLKESFSLGAETATGDAEVDRIWFAPNVWPREVPEL
Mvan_4054|M.vanbaalenii_PYR-1 AEANGYAEGTETPPDLKETFSLGAETATGDAEVDRIWFAPNVWPREVPAL
MAB_4434c|M.abscessus_ATCC_199 RLGGELTGGLTDWREQIDVGPERAASPTADGRDYMWLQGPNQWPAAVPEL
MAV_4913|M.avium_104 RLGGERTRGAVDWREQIDIGPQRPPIGGLDKSDYRWLQGPNQWPAALPEL
TH_4524|M.thermoresistible__bu PPGEEVFAGGTADTKEAFDLSYELPADDPRYLAGDPLLGPNQWP-ELTGF
MSMEG_2569|M.smegmatis_MC2_155 YKSQIRPSVGTADEKESYQFTRPR------------MDGLWPAPDELDGF
. . . . * : :
Mflv_2580|M.gilvum_PYR-GCK APLVEEYTAQMRRVADDLLALCAHALGLSVNPF----AALASAPTWTMNI
Mvan_4054|M.vanbaalenii_PYR-1 QPLLTEYTAQMRGVADDLLALFAHALKLPANPF----AELASTPTWTMNI
MAB_4434c|M.abscessus_ATCC_199 RPALESWDIALAEVGRKLLREWAIALGSDGAVFS---EAFGDKPATLIKV
MAV_4913|M.avium_104 PGLIAEWDAALSGVARTLLRHWAAALGSPADVFD---AAFADAPATLIKI
TH_4524|M.thermoresistible__bu REAVTAWYDAVFALSRAILRAFAVALGQPPDRF----DRYVTTPPSQLRL
MSMEG_2569|M.smegmatis_MC2_155 RDTIEDFERRCWRLAMDILSCFAVRLGFDREFFARAHDPDAPTYQSTLRL
: : :. :* * * * :.:
Mflv_2580|M.gilvum_PYR-GCK NHYPPVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEQ----
Mvan_4054|M.vanbaalenii_PYR-1 NHYPPVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSED----
MAB_4434c|M.abscessus_ATCC_199 IRYPSDGTTSQ------GVGAHRDSGVLTLLLTEPEVGGLQVEVDG----
MAV_4913|M.avium_104 IRYPGRAAGPQ------GVGAHRDAGVLTLLLAEPGSRGLQVRRGGPR-G
TH_4524|M.thermoresistible__bu IHYPADPSAVDRP----GIGAHTDYECFTLLR--PTAPGLEVLNAAG---
MSMEG_2569|M.smegmatis_MC2_155 LHYYAFPAELVGRDDVWRAGAHTDFDALTLLFQRSGQPGLQVLPGAEADQ
:* *.* * .*:* . **:*
Mflv_2580|M.gilvum_PYR-GCK AGWENAPYDPAALTVNIGDLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVS
Mvan_4054|M.vanbaalenii_PYR-1 AGWQDAPYDPDALTVNIGDLLEYWSGRRWPSGRHRVLPPQPGAPEEDLVS
MAB_4434c|M.abscessus_ATCC_199 -AWLEAPGREGAFIVNIGELLERASGGYLRATRHRVT---LTG--APRIS
MAV_4913|M.avium_104 DGWIDVPPRQGAFIVNIGELLEAATRGYLRATEHRVN---LAGSTAERIS
TH_4524|M.thermoresistible__bu -QWIDVPYLDDAFVLNIGDLLEIWTNGAFVATTHRVR-----RVTSERYS
MSMEG_2569|M.smegmatis_MC2_155 QVWTPVHPSDDVITCNIGDMLMRWSDDLLPSNFHRVRAPRPGESLDPRYS
* . .: ***::* : : *** *
Mflv_2580|M.gilvum_PYR-GCK LIYFYEANHDALVTPLSPP--------------IGRAEGLEPVLSADFIK
Mvan_4054|M.vanbaalenii_PYR-1 LIYFYEANHDALVTPLDPP--------------VGRVSGLAPVTSADFIK
MAB_4434c|M.abscessus_ATCC_199 VAYFFNPRLDARIPVLELPPELRDRARG---VSADPDDPIHATYGENAWK
MAV_4913|M.avium_104 VPYFFNPRLDARIPVLSLPPELRARAGERWTPSEDPADPIFSVYGRNAWK
TH_4524|M.thermoresistible__bu FPLFVNVDADTEVAPLAEFVDGTARYAP---VIAGEHLFAQTARSFRYLQ
MSMEG_2569|M.smegmatis_MC2_155 VAYFAQANTDVLIE--------------------SPKGTYPPITAAEYLR
. * : *. : . . . :
Mflv_2580|M.gilvum_PYR-GCK QRLDAITVS-------------------
Mvan_4054|M.vanbaalenii_PYR-1 ERLDAITVG-------------------
MAB_4434c|M.abscessus_ATCC_199 SRLRAHPDVAAVHGHLDS----------
MAV_4913|M.avium_104 SRLRSHPDVASAHGFSAHHGAAD-----
TH_4524|M.thermoresistible__bu DRIRRGEVSLPDGAYPLSAFGRRAASPR
MSMEG_2569|M.smegmatis_MC2_155 RRIAANFG--------------------
*: