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MKPAPFQYLRPATVAEALEQLASYPDAKVMAGGQSLMALMNLRLARPGVIVDIGRLDELRRIFDDTEDLI LGALVTHRTVETDPLIAARAPLLADAARYIGHVGIRNRGTIGGSVAHADPAAEMPLSTLVLDATFHVESA TRGRRQVRAEDMFVSYFTSALEPDELITWVSIPAARYGQGWGFVEYAHQHGDYGLAGAGAVLGLDADGRI CELRCAVLSAADRPLLFVGDDAVGERPSARLWETLASRWARSTDPSSDDPDYSRQLCETALFEALTEATR RVGERQERVDAYR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2463 | - | - | 100% (293) | nicotine dehydrogenase chain A |
| M. smegmatis MC2 155 | MSMEG_5882 | - | 9e-40 | 40.71% (226) | carbon monoxide dehydrogenase medium chain |
| M. smegmatis MC2 155 | MSMEG_0744 | - | 2e-30 | 31.94% (288) | carbon monoxide dehydrogenase medium chain |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0382c | - | 9e-25 | 30.45% (266) | carbon monoxyde dehydrogenase medium subunit |
| M. gilvum PYR-GCK | Mflv_1571 | - | 1e-41 | 37.21% (301) | carbon-monoxide dehydrogenase (acceptor) |
| M. tuberculosis H37Rv | Rv0375c | - | 9e-25 | 30.45% (266) | carbon monoxyde dehydrogenase medium subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0622 | coxM_3 | 1e-41 | 43.58% (218) | aerobic-type carbon monoxide dehydrogenase, CoxM_3 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1271 | - | 1e-46 | 40.77% (287) | carbon monoxide dehydrogenase medium chain |
| M. ulcerans Agy99 | MUL_0587 | coxM_2 | 1e-41 | 43.12% (218) | aerobic-type carbon monoxide dehydrogenase, CoxM_2 |
| M. vanbaalenii PYR-1 | Mvan_5185 | - | 4e-42 | 36.91% (298) | carbon-monoxide dehydrogenase (acceptor) |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0622|M.marinum_M MKPASFDYHRPDTAEEAVGLLAELGEDAKILAGGQSLVPMLSMRLAFFDH
MUL_0587|M.ulcerans_Agy99 MKPASFDYHRPDTAEEAVDLLAELGEDAKILPGGQSLVPMLSMRLAFFDH
TH_1271|M.thermoresistible__bu MKPAPFAYHRPADLTEATQLLAEFGDEAKVLAGGQSLVPMLNLRLAFFDH
Mflv_1571|M.gilvum_PYR-GCK MKAAPFAYHRPDTVADAVSLLGEYGDDAKILAGGQSLVPMLAMRLTHFEN
Mvan_5185|M.vanbaalenii_PYR-1 MKAAPFAYHRPDTVADAVSMLGEFGDDAKILAGGQSLVPMLAMRLTHFEN
MSMEG_2463|M.smegmatis_MC2_155 MKPAPFQYLRPATVAEALEQLASY-PDAKVMAGGQSLMALMNLRLARPGV
Mb0382c|M.bovis_AF2122/97 -------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPEY
Rv0375c|M.tuberculosis_H37Rv -------------MDHAIGLLDRLGEGARVVAGGHSLLPMMKLRIANPEY
.* * *:::.**:**:.:: :*::
MMAR_0622|M.marinum_M LIDISRLAELQGIQLRN-----DQLWIGAGTPDSKVGTDSQVRQSVPLLT
MUL_0587|M.ulcerans_Agy99 LIDISRLGELQGIRLRD-----DQLWIGAGTPDSKVGTNSQVHQSIPLLA
TH_1271|M.thermoresistible__bu LVDISRLDELKGIERSN-----GSLTIRAGTTDATVGADDQVRSAVPLLT
Mflv_1571|M.gilvum_PYR-GCK LIDISRIEELRNIELRNGAD--SSVRIGAGTPHALVGMDDEVAESVPLLT
Mvan_5185|M.vanbaalenii_PYR-1 LIDISRVDELRNIEPRG-----DAVRIGAGTPHALVGMDDEVAESVPLLT
MSMEG_2463|M.smegmatis_MC2_155 IVDIGRLDELRRIFDDT-----EDLILGALVTHRTVETDPLIAARAPLLA
Mb0382c|M.bovis_AF2122/97 LVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIFR
Rv0375c|M.tuberculosis_H37Rv LVDINDLAPELGYVVVGGINNPNLVRLGAMTRHREILDSDALAAVCPIFR
::**. : : : * . . : . : *::
MMAR_0622|M.marinum_M RATPYIGHFQIRNRGTLGGSIAHADAAGEYPTVALTLDAVMEVLSP-RGY
MUL_0587|M.ulcerans_Agy99 RATPYIGHFQIRNRGTLGGSIAHADAAGEYPTVALTLDAVMEVLSP-RGH
TH_1271|M.thermoresistible__bu RATPHIGHFQIRNRGTFGGSIAHADPAGEYPAVALALDAQMEAVSP-TGR
Mflv_1571|M.gilvum_PYR-GCK LATPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEIEATSG-RGT
Mvan_5185|M.vanbaalenii_PYR-1 LSTPHIGHFQIRTRGTLGGAIAHADPAAEYAAVALALDAEMEATSA-RGT
MSMEG_2463|M.smegmatis_MC2_155 DAARYIGHVGIRNRGTIGGSVAHADPAAEMPLSTLVLDATFHVESATRGR
Mb0382c|M.bovis_AF2122/97 DAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGP-SGE
Rv0375c|M.tuberculosis_H37Rv DAERVIADPVVRNRGTLGGSLCQADPAEDLSTVCTVLDAVCLAKGP-SGE
: *.. :*.***:**::.:**.* : . .*** . . *
MMAR_0622|M.marinum_M REIPAAEFFTGLWETAMEPDEVLTGVRFPTWTGKSGFAVREFSRRHGDFA
MUL_0587|M.ulcerans_Agy99 RKIPAAEFFTGLWETAMEPDEVLTGVRFPTWTGKSGFAMREFSRRHGDFA
TH_1271|M.thermoresistible__bu REIAAADFFQGLWETALEPDEILAAVRFPVWDGRCGFAVHEFARRHGDFA
Mflv_1571|M.gilvum_PYR-GCK RRIPAAEFFTGLWETALASDEILTAVSFPVWSGRCGFAVQEFARRHGDFA
Mvan_5185|M.vanbaalenii_PYR-1 RRIPAAEFFTGLWETALAADEILTAVSFPVWTGHCGFAVQEFARRHGDFA
MSMEG_2463|M.smegmatis_MC2_155 RQVRAEDMFVSYFTSALEPDELITWVSIPAARYGQGWGFVEYAHQHGDYG
Mb0382c|M.bovis_AF2122/97 REIAIDDFLVGPYETALAHNEVLIEVRIPLRHN-TSSAYAKVERRVGDWA
Rv0375c|M.tuberculosis_H37Rv REIAIDDFLVGPYETALAHNEVLIEVRIPLRHN-TSSAYAKVERRVGDWA
*.: ::: . : :*: :*:: * :* . . : :: **:.
MMAR_0622|M.marinum_M IAGAAVAVQLDDEHRVSRCAIGLLGLGATPRRATAAEAAVLGKPIDELVP
MUL_0587|M.ulcerans_Agy99 IAGAAVAVQLDDEHRVSRCAIGLLGLGPTPRRATAAEAAVLGKPIDELVP
TH_1271|M.thermoresistible__bu IAGAVLAVRLDGDDRISRCGIGLLGLGSTPRRATAAEQAILGRPVSEVDA
Mflv_1571|M.gilvum_PYR-GCK IAGATVAVALDEDDTVTRCGIGMLGMGSTPERGTAAEAAVLGRPVADITA
Mvan_5185|M.vanbaalenii_PYR-1 IAGATLAVELDGRDRVARCGIGLLGMGSTPERGTPAEQAVVGRPVTDITA
MSMEG_2463|M.smegmatis_MC2_155 LAGAGAVLGLDADGRICELRCAVLSAADRP-LLFVGDDAVGERPSARLWE
Mb0382c|M.bovis_AF2122/97 ITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEVF
Rv0375c|M.tuberculosis_H37Rv ITAAGAAVTLDG-QTILAARVGLTAVNPDPVALAELSAGLVGQPATEEVF
::.* .: ** : .: . * . .: :*
MMAR_0622|M.marinum_M EQIGQSAMSGLADIASDLQGSGSYRAQVGAVMTTRAWSRAVQEANAETAH
MUL_0587|M.ulcerans_Agy99 EQIGQSAMSGLDDIASDLQGPASYRAQVGAVMTTRAWSRAVQEANAETAH
TH_1271|M.thermoresistible__bu DELGVLAMEGLDDIPADLQGSADYRRRVGAAMVARAWTDASREAASA---
Mflv_1571|M.gilvum_PYR-GCK EELGRLAVSTLHDIPADLQGSAAYRSRVCATMVARAWSEATTAARHTTEA
Mvan_5185|M.vanbaalenii_PYR-1 EEVGRLAVSELHDVPADLQGRPAYRSKVGATMVARAWSQATTAALETREA
MSMEG_2463|M.smegmatis_MC2_155 TLASRWARS--TDPSSD---DPDYSRQLCETALFEALTEATRRVGERQER
Mb0382c|M.bovis_AF2122/97 AEAGRRAAQA-CTPVTDVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPAA
Rv0375c|M.tuberculosis_H37Rv AEAGRRAAQA-CTPVTDVRGTAEYKRHLAGELTVRTLRTAAGRVLGAPAA
. * . :* * :: .: * .
MMAR_0622|M.marinum_M A----
MUL_0587|M.ulcerans_Agy99 A----
TH_1271|M.thermoresistible__bu -----
Mflv_1571|M.gilvum_PYR-GCK LHA--
Mvan_5185|M.vanbaalenii_PYR-1 LNA--
MSMEG_2463|M.smegmatis_MC2_155 VDAYR
Mb0382c|M.bovis_AF2122/97 PEA--
Rv0375c|M.tuberculosis_H37Rv PEA--