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MPVRLGIGIPTTIGPPRAPELSRWCREAEERGASSLSCVDRLNYPNLDSFLALAAAAAVTHTVRLLATVV VAPLRGNGELLRKQLANLHHFSGRRFDVGLGVGRRDDDYVASDVDFSTRGKRFDAQLDRLFGTGEDKSPE LPCVMFGGQSPATLRRIARWGGGWVSAAGLGGLQSTIEFSQQVHEAWSSANRPGKPRLVALAYAAVGKQA ATHARTHMQEYYGFLGTEGVDRLTRQVIKGHDQLTDARGRLADAGFDELIVLPTSDSLDQLALLDESTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2162 | - | - | 100% (279) | MmcJ protein |
| M. smegmatis MC2 155 | MSMEG_4967 | - | 1e-21 | 29.75% (279) | hypothetical protein MSMEG_4967 |
| M. smegmatis MC2 155 | MSMEG_3609 | - | 3e-15 | 34.52% (197) | hydride transferase 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 2e-11 | 26.39% (216) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2283 | - | 6e-16 | 27.85% (298) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0953c | - | 2e-11 | 26.39% (216) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3271 | - | 7e-23 | 29.71% (276) | hypothetical protein MAB_3271 |
| M. marinum M | MMAR_4128 | - | 1e-22 | 31.52% (276) | flavin-dependent oxidoreductase |
| M. avium 104 | MAV_3379 | - | 2e-39 | 34.97% (286) | MmcJ protein |
| M. thermoresistible (build 8) | TH_2001 | - | 2e-20 | 30.11% (279) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3991 | - | 4e-22 | 31.16% (276) | flavin-dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4383 | - | 6e-22 | 30.82% (292) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2162|M.smegmatis_MC2_155 MPVRLGIGIPTTIGPPRAPELSRWCR-------------------EAEER
MAV_3379|M.avium_104 --MKLGIGLPNHIADVPGPAVAQWSR-------------------RGEEL
MMAR_4128|M.marinum_M ------MTMPVMEPDLDANVLKTWAR-------------------AVDEG
MUL_3991|M.ulcerans_Agy99 -----------MEPDLDANVLKTWAR-------------------AVDEG
TH_2001|M.thermoresistible__bu ------MTMPVMEPDLDAATLRTWAR-------------------AIDDG
Mflv_2283|M.gilvum_PYR-GCK ------MTMPVMEPDLDREMLKSWAK-------------------TVDEG
Mvan_4383|M.vanbaalenii_PYR-1 --------MPVMEPDLDRATLRSWAQ-------------------LVDGG
MAB_3271|M.abscessus_ATCC_1997 --MDIGIALPFMCRDYTRESTITWAR-------------------LADEG
Mb0978c|M.bovis_AF2122/97 --MHYGLVLFTSDRGITPAAAARLAESHGFRTFYVPEHTHIPVKRQAAHP
Rv0953c|M.tuberculosis_H37Rv --MHYGLVLFTSDRGITPAAAARLAESHGFRTFYVPEHTHIPVKRQAAHP
..
MSMEG_2162|M.smegmatis_MC2_155 GASSLSCVDRLNYPNLDSFLALA---AAAAVTHTVRLLATVVVAPLRGNG
MAV_3379|M.avium_104 GFESVATIDRLFSSGVDSLIALA---TAAGATNELTLVTNVLLAPMYP-V
MMAR_4128|M.marinum_M PFSALCWGERIAFDNPDSLTLLG---ALAAWTDRVRLVTTVIVPQLHD-P
MUL_3991|M.ulcerans_Agy99 TFSALCWGERIAFDNPDSSTLLG---ALAAWTDRVRLVTTVIVPQLHD-P
TH_2001|M.thermoresistible__bu PFSALCWGERIAFDNPDSLTLLG---ALAAWTDRVRLVTTVVVPQLHD-P
Mflv_2283|M.gilvum_PYR-GCK PFSSLCWGERIAFDNPESLTLLGALGALGAWTERVRLVTTVVIPQLHD-P
Mvan_4383|M.vanbaalenii_PYR-1 PFSSLCWGERIAFDNPESLTLLG---ALAAWTDRVRLVTTVVIPQLHD-P
MAB_3271|M.abscessus_ATCC_1997 PFSTISSGERISYHNQDMWVTLA---AAAAVTERVRILANVSVLPAHP-V
Mb0978c|M.bovis_AF2122/97 TTGDASLPDDRYMRTLDPWVSLG---AASAVTSRIRLATAVALPVEHD-P
Rv0953c|M.tuberculosis_H37Rv TTGDASLPDDRYMRTLDPWVSLG---AASAVTSRIRLATAVALPVEHD-P
. : : *. : .. * : : : * :
MSMEG_2162|M.smegmatis_MC2_155 ELLRKQLANLHHFSGRRFDVGLGVGRRDDDYVASDVDFSTRGKR-FDAQL
MAV_3379|M.avium_104 IPLAKQLVSLARVSGGRLTVGLGVGNRSDEYAGTGADFHRRGRA-LDAQV
MMAR_4128|M.marinum_M VMLAKALATGDMLSGGRLTVGIGVGGRREDYLAVGADPKTQTMGGMATRV
MUL_3991|M.ulcerans_Agy99 VMLAEALATGDMLSGGRLTVGIGVGGRREDYLAVGADPKTQTMGGMATRV
TH_2001|M.thermoresistible__bu VLLAKGLATGDVLSGGRLTVGIGVGGRHEDYRAVGADPATQTMREMAERV
Mflv_2283|M.gilvum_PYR-GCK VMLAKQLATGDVLSGGRLTVGIGVGGRHEDYQAVGADPATQTMRQMAERV
Mvan_4383|M.vanbaalenii_PYR-1 VMLAKQLATGDMLCGGRLTVGIGVGGRHEDYRAVGVDPATQTMRQMAERV
MAB_3271|M.abscessus_ATCC_1997 PLVAKQAATLDVLSEGRFILGVGVGGREHDYRCLDASFGRRHQR-LDDQV
Mb0978c|M.bovis_AF2122/97 ITLAKSIATLDHLSHGRVSVGVGFGWNTDELVDHGVPPG-RRRTMLREYL
Rv0953c|M.tuberculosis_H37Rv ITLAKSIATLDHLSHGRVSVGVGFGWNTDELVDHGVPPG-RRRTMLREYL
: : .. .. *. :*:*.* . .: .. : : :
MSMEG_2162|M.smegmatis_MC2_155 DRLFGTG-------EDK--------------SPELPCVMFGGQSPATLRR
MAV_3379|M.avium_104 ERLRSLW-------AGEPLADGTALCG----APVRIPLLFGGRSAATVRR
MMAR_4128|M.marinum_M AVMKRVW-------AGEQISESVRPVGPLPVQPGGPPLLVGTIGPKTLRS
MUL_3991|M.ulcerans_Agy99 AVMKRVW-------AGEQISESVRPVGPLPVQPGGPPLLVGTIGPKTLRS
TH_2001|M.thermoresistible__bu AVMKRVW-------AGEKVTESVLPVGPPPVQSGGPPLLVGTIGPKTVRS
Mflv_2283|M.gilvum_PYR-GCK EIMKRVW-------AGEKITDSTLPVGPPPVQPGGPPLQVGTLGPKAVRS
Mvan_4383|M.vanbaalenii_PYR-1 AVMKRVW-------AGEKVTESTLPVGPPPVQPGGPELHVGTLGPKTVRS
MAB_3271|M.abscessus_ATCC_1997 AELRRLW-------RGEPPFEGADPVGPAPVQDGGPPVVAAAIGPKSLAR
Mb0978c|M.bovis_AF2122/97 EAMRALWTQEEACYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKW
Rv0953c|M.tuberculosis_H37Rv EAMRALWTQEEACYDGEFVKFGPSWAWPKPVQPHIPVLVGAAGTEKNFKW
: .: : . .
MSMEG_2162|M.smegmatis_MC2_155 IARWGGGWVSAAGLGGLQSTIEFSQQVHEAWSSANRPGKPRLVALAYAAV
MAV_3379|M.avium_104 VVTTGDGWAAGA-VRLYDEQADVAARIRSGWQDAGRPARPYLQASVNFAL
MMAR_4128|M.marinum_M AAPWADGLAGTTLDLDAAKQNELFDVARAAWAQAGKPKP-HLATSFWFAF
MUL_3991|M.ulcerans_Agy99 AAPWADGLAGTTLDLDVAKQNELFDVARAAWAQAGKPKP-HLATSFWFAF
TH_2001|M.thermoresistible__bu AAAWADGMAGTTLDLDTGKQNELFDIARSAWAQAGKPAP-HLATSFWFAL
Mflv_2283|M.gilvum_PYR-GCK AASWAEGIAGTTLDLDLDKQNDLFDVARDAWREAGNEEP-HLATSFWFAI
Mvan_4383|M.vanbaalenii_PYR-1 AAAWADGLAGITMDLAVDKQGELFDVARDAWQQAGKGKP-HLATSFWFAI
MAB_3271|M.abscessus_ATCC_1997 AARWADGITGFSVSGAPAELTYSADSARAAWQAAGHAEPPVLSSGCFYTL
Mb0978c|M.bovis_AF2122/97 IARSADGWITTPRDVDIDEP---VKLLQDIWAAAGRDGLPQIVALDVKPV
Rv0953c|M.tuberculosis_H37Rv IARSADGWITTPRDVDIDEP---VKLLQDIWAAAGRDGLPQIVALDVKPV
. . * . . : * *.. : : ..
MSMEG_2162|M.smegmatis_MC2_155 G-KQAAT-HARTHMQEYYGFLGTEGVDRLTRQVIKG--HDQLTDARGRLA
MAV_3379|M.avium_104 GPAETVA-AGRDHLARYYAFAPGYAQVNVADMVCSA--ADARDTVR-RYR
MMAR_4128|M.marinum_M GPQADARAQVHRHLRRYMNWIPAEYVDAMAPTTGWAGSEDELLAVLRRFE
MUL_3991|M.ulcerans_Agy99 GPQADARAQVHRHLRRYMNWIPAEYVDAMAPTTGWAGSEDELLAVLRRFE
TH_2001|M.thermoresistible__bu GAADTARDQVHRHLRRYMNWIPVEFVDAMAPTTGFAGSEDELHRVLRRFR
Mflv_2283|M.gilvum_PYR-GCK GDGDAPREQVHRHLLRYMNWIPSEFVDAMAPTTGFAGTAEELRAVLEGFA
Mvan_4383|M.vanbaalenii_PYR-1 GDGDAPRAQVHRHLLRYMNWIPAEFVDALAPTTGFAGTADDLREVLQRFA
MAB_3271|M.abscessus_ATCC_1997 G-IPGAESELKQFTSEYLAIFGTQIAEN-VPKTLTNFDADALNRTLDGAE
Mb0978c|M.bovis_AF2122/97 P------------------------------------------DKLARWA
Rv0953c|M.tuberculosis_H37Rv P------------------------------------------DKLARWA
MSMEG_2162|M.smegmatis_MC2_155 DAGFDELIVLPTSDSLDQLALLDESTA-------
MAV_3379|M.avium_104 DLGFDRLLFHPTSASVEQLDYLADAILGCL----
MMAR_4128|M.marinum_M EVGTDEVQLIPTSSDVEQLRRAIDVVTRFGTA--
MUL_3991|M.ulcerans_Agy99 EIGTDEVPLIPTSSDVEQLRRAIDVVTRFGAA--
TH_2001|M.thermoresistible__bu DIGADEVHLIPTSADVDQVRRAAEVVREFGEP--
Mflv_2283|M.gilvum_PYR-GCK GIGTDEVHLIPTSSDIGQVRRAAEVVADFA----
Mvan_4383|M.vanbaalenii_PYR-1 DIGTDEVHLIPTSQDIDQVRRVAEVIDDFS----
MAB_3271|M.abscessus_ATCC_1997 EAGLDEFILVPGASDVAVIEATIELIQRR-----
Mb0978c|M.bovis_AF2122/97 ELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV
Rv0953c|M.tuberculosis_H37Rv ELGVTEVLFGMPDRSADDAAAYVERLAAKLACCV
* .. . . :