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M. smegmatis MC2 155 MSMEG_2100 (-)

annotation: peptidase family protein M20/M25/M40
coordinates: 2176102 - 2177433
length: 443

EFDFEKFADLIDESLIVDLAKRVIETPSPTGEEYDLAVLLKEVYGDLGLESELQTLYSDGDVDRVNVAAR
WRGNGTGPHVLFSGHLDSSVRGDEPWLIGDGWKNTPVVDDRIIWGNGIFNMKGAFVCYAAMMDAMRRAGV
SFAGDVVIAGTCGEIELGSVDEFTGRRYDSQGVGLRYLLQHGYVADFHILGEPTGLVPHVGHMGSTWAKI
TTSGSFTHSAWADRSTSAIDEMWTLRHELNDWVADYRKNFVFQGVAPQVNFAAIRGGHPWRAARTANTCS
MYVDIRFPPNVFPIDVQRDFTSRVTEIAAKHLRGDARVDWYMSRPGALVSPSSLVVERMVDAHNQAAGED
LGPVFGPPWCSDAIDSNRLGIPTVLYGLGRTRVDDSASPNASGDPRSANGEYVCIDDMVTAAKAYGAACA
GLMGLDIDEVHRTRQPMPSVEL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2100--100% (443)peptidase family protein M20/M25/M40
M. smegmatis MC2 155MSMEG_2491-3e-1726.94% (438) acetylornithine deacetylase
M. smegmatis MC2 155MSMEG_3397-5e-0923.13% (307) acetylornithine deacetylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923MLBr_01059dapE8e-0525.87% (201) succinyl-diaminopimelate desuccinylase
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_1349dapE1e-0523.24% (370) dipeptidase
M. thermoresistible (build 8)TH_1840dapE6e-0626.50% (200) PROBABLE SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE DAPE
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4515-1e-0525.00% (332) dipeptidase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1840|M.thermoresistible__bu      ------VALDLHGD--PIALTAALVDIPSESRHE---QRIADEIETALRE
Mvan_4515|M.vanbaalenii_PYR-1       -------MLDLHGD--PIALTAALVDIPSESRHE---KRIADEIETALRE
MLBr_01059|M.leprae_Br4923          -------MLDLRGD--PIELTAALVDIPSESRAE---ARIADAVETALRA
MAV_1349|M.avium_104                -------MLDLTGD--PVALTAALVDIPSESRDE---ARLADEVEAALRS
MSMEG_2100|M.smegmatis_MC2_155      MEFDFEKFADLIDESLIVDLAKRVIETPSPTGEEYDLAVLLKEVYGDLGL
                                             ** .:   : *:  ::: ** :  *     : . :   *  

TH_1840|M.thermoresistible__bu      QTRGFEVIRNG-----NAVLARTNHGRPTRVLLAGHTDTVPAADN-----
Mvan_4515|M.vanbaalenii_PYR-1       QTAGFEIVRNG-----DAVLARTDFGRPSRVLLAGHIDTVPAADN-----
MLBr_01059|M.leprae_Br4923          QTAGFEIVRNG-----NAVLARTSLHRPARVLLAGHLDTVPVAGN-----
MAV_1349|M.avium_104                QTSGFEIVRNG-----NAVLARTDRGRPSRVLLAGHLDTVPVAGN-----
MSMEG_2100|M.smegmatis_MC2_155      ESELQTLYSDGDVDRVNVAARWRGNGTGPHVLFSGHLDSSVRGDEPWLIG
                                    ::    :  :*     :..    .    .:**::** *:   ..:     

TH_1840|M.thermoresistible__bu      ----LPSRRVGDLLYGCGTSDMKSGDAVFLHLAATVTEPAHDIT---LVM
Mvan_4515|M.vanbaalenii_PYR-1       ----LPSRLADGVLHGCGTSDMKAGDAVFLHLAATVAEPAHDIT---LVM
MLBr_01059|M.leprae_Br4923          ----LPSRCEKDVLHGCGTVDMKSGDAVFLHLAATVTEPVHDLT---LMF
MAV_1349|M.avium_104                ----LPSRREDGDLYGCGTADMKSGDAVFLHLAATVADPAHDLT---LVM
MSMEG_2100|M.smegmatis_MC2_155      DGWKNTPVVDDRIIWGNGIFNMKGAFVCYAAMMDAMRRAGVSFAGDVVIA
                                         ..      : * *  :**.. . :  :  ::  .  .::   :: 

TH_1840|M.thermoresistible__bu      YDCEEIEA-----------AANGLGRIERELPDWLRADVAILGEPSGGFI
Mvan_4515|M.vanbaalenii_PYR-1       YDCEEIEA-----------SANGLGRIERELPEWLAADVAILGEPSGGLI
MLBr_01059|M.leprae_Br4923          YDCEEIDS-----------AANGLVRIERELPEWLAADVAILGEPTGGYI
MAV_1349|M.avium_104                YDCEEIDA-----------AANGLGRIQRELPDWLSADVAILGEPTGGYI
MSMEG_2100|M.smegmatis_MC2_155      GTCGEIELGSVDEFTGRRYDSQGVG-LRYLLQHGYVADFHILGEPTGLVP
                                      * **:             ::*:  :.  * .   **. *****:*   

TH_1840|M.thermoresistible__bu      EAGCQGTLRMVISTTGTRAHSARSWLGDNAIHKLAPVLDRLSDYRAR---
Mvan_4515|M.vanbaalenii_PYR-1       EAGCQGTLRVIVRATGTRAHSARSWLGDNAIHKLSDVLARLRSYQAR---
MLBr_01059|M.leprae_Br4923          EAGCQGTLRVVINAAGSRAHSARSWLGDNAIHKLGAVLDRLAAYRAR---
MAV_1349|M.avium_104                EAGCQGTLRVVVSATGTRAHSARSWLGDNAIHKLGAVLQRLAGYQAR---
MSMEG_2100|M.smegmatis_MC2_155      HVGHMGSTWAKITTSGSFTHSAWADRSTSAIDEMWTLRHELNDWVADYRK
                                    ..*  *:    : ::*: :*** :  . .**.::  :  .*  : *    

TH_1840|M.thermoresistible__bu      SVDIDGCVYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAP-------DR
Mvan_4515|M.vanbaalenii_PYR-1       SVDIDGCVYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAP-------DR
MLBr_01059|M.leprae_Br4923          TVDIDGCVYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAP-------DR
MAV_1349|M.avium_104                SVEIDGCTYREGLSAVRIDGGVAGNVIPDAAAVTVNFRFAP-------DR
MSMEG_2100|M.smegmatis_MC2_155      NFVFQGVAPQVNFAAIRGGHPWRAARTANTCSMYVDIRFPPNVFPIDVQR
                                    .. ::* . : .::*:* .    .   .::.:: *: **.*       :*

TH_1840|M.thermoresistible__bu      TVEQAERHVREVFDGLDVRMELTDAAGGALPGLQQPAAAQLVAAAGGQVR
Mvan_4515|M.vanbaalenii_PYR-1       SVEQAYAHVREVFDRLDVTIELTDAAAGALPGLTRPAAAALVEAAGGQVR
MLBr_01059|M.leprae_Br4923          SVAAALRHVHDVFDGLDVQIEQTDAAVGALPGLSQPAAKALVEAADGQVR
MAV_1349|M.avium_104                SPAEALQHVRDVLDGLDVRIEQTDAAAGALPGLSQPAAKALVEAAGGRVR
MSMEG_2100|M.smegmatis_MC2_155      DFTSRVTEIAAKHLRGDARVDWYMSRPGALVSPSSLVVERMVDAHNQAAG
                                           .:       *. ::   :  *** .    ..  :* * .  . 

TH_1840|M.thermoresistible__bu      AKYG-------WTDVARFAALGVPAVNYGPGDPNLAHKSD----------
Mvan_4515|M.vanbaalenii_PYR-1       AKYG-------WTDVSRFAALGIPAVNYGPGDPNLAHRVD----------
MLBr_01059|M.leprae_Br4923          AKYG-------WTDVSRFAALGVPAVNYGPGDPNLAHRHD----------
MAV_1349|M.avium_104                AKYG-------WTDVARFAALGIPALNFGPGDPNLAHRRD----------
MSMEG_2100|M.smegmatis_MC2_155      EDLGPVFGPPWCSDAIDSNRLGIPTVLYGLGRTRVDDSASPNASGDPRSA
                                     . *        :*.     **:*:: :* * ..: .  .          

TH_1840|M.thermoresistible__bu      --EHVDVTAITAVTDVLRRYLSG---------------------
Mvan_4515|M.vanbaalenii_PYR-1       --ESVDVAQITAVTDMLRRYLIG---------------------
MLBr_01059|M.leprae_Br4923          --ERVPVVQITAAVDMLRRYLGG---------------------
MAV_1349|M.avium_104                --ERVAVAAITAAADLLRGYLSG---------------------
MSMEG_2100|M.smegmatis_MC2_155      NGEYVCIDDMVTAAKAYGAACAGLMGLDIDEVHRTRQPMPSVEL
                                      * * :  :.:...       *