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LDLHGDPIALTAALVDIPSESRHEKRIADEIETALREQTAGFEIVRNGDAVLARTDFGRPSRVLLAGHID TVPAADNLPSRLADGVLHGCGTSDMKAGDAVFLHLAATVAEPAHDITLVMYDCEEIEASANGLGRIEREL PEWLAADVAILGEPSGGLIEAGCQGTLRVIVRATGTRAHSARSWLGDNAIHKLSDVLARLRSYQARSVDI DGCVYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAPDRSVEQAYAHVREVFDRLDVTIELTDAAAGALP GLTRPAAAALVEAAGGQVRAKYGWTDVSRFAALGIPAVNYGPGDPNLAHRVDESVDVAQITAVTDMLRRY LIG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4515 | - | - | 100% (354) | dipeptidase |
| M. vanbaalenii PYR-1 | Mvan_3489 | - | 1e-06 | 22.88% (389) | hypothetical protein Mvan_3489 |
| M. vanbaalenii PYR-1 | Mvan_4122 | - | 9e-05 | 29.73% (222) | hypothetical protein Mvan_4122 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1234 | dapE | 1e-159 | 78.25% (354) | succinyl-diaminopimelate desuccinylase |
| M. gilvum PYR-GCK | Mflv_2180 | - | 0.0 | 91.53% (354) | dipeptidase |
| M. tuberculosis H37Rv | Rv1202 | dapE | 1e-159 | 78.25% (354) | succinyl-diaminopimelate desuccinylase |
| M. leprae Br4923 | MLBr_01059 | dapE | 1e-164 | 80.79% (354) | succinyl-diaminopimelate desuccinylase |
| M. abscessus ATCC 19977 | MAB_1336 | - | 1e-156 | 79.20% (351) | succinyl-diaminopimelate desuccinylase |
| M. marinum M | MMAR_4235 | dapE | 1e-167 | 83.52% (352) | succinyl-diaminopimelate desuccinylase DapE |
| M. avium 104 | MAV_1349 | dapE | 1e-166 | 81.64% (354) | dipeptidase |
| M. smegmatis MC2 155 | MSMEG_5103 | dapE | 1e-171 | 84.62% (351) | dipeptidase |
| M. thermoresistible (build 8) | TH_1840 | dapE | 1e-174 | 85.27% (353) | PROBABLE SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE DAPE |
| M. ulcerans Agy99 | MUL_0954 | dapE | 1e-168 | 83.52% (352) | succinyl-diaminopimelate desuccinylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1234|M.bovis_AF2122/97 -MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNG
Rv1202|M.tuberculosis_H37Rv -MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNG
MMAR_4235|M.marinum_M -MLDLRGDPIDLTAALIDIPSESRDEARIADEVEAALRAQTSGFEIIRNG
MUL_0954|M.ulcerans_Agy99 -MLDLRGDPIDLTAALIDIPSESRDEARIADEVEAALRAQTSGFEIIRNG
MLBr_01059|M.leprae_Br4923 -MLDLRGDPIELTAALVDIPSESRAEARIADAVETALRAQTAGFEIVRNG
MAV_1349|M.avium_104 -MLDLTGDPVALTAALVDIPSESRDEARLADEVEAALRSQTSGFEIVRNG
Mvan_4515|M.vanbaalenii_PYR-1 -MLDLHGDPIALTAALVDIPSESRHEKRIADEIETALREQTAGFEIVRNG
Mflv_2180|M.gilvum_PYR-GCK -MLDLHADPIALTAALVDIPSESRHEARIADAIEAALREQTTGFEVVRNG
MSMEG_5103|M.smegmatis_MC2_155 MGLDLSADPIALTAALVDIPSVSRDERRIADEIEAALRAQAPHFEVIRNG
TH_1840|M.thermoresistible__bu VALDLHGDPIALTAALVDIPSESRHEQRIADEIETALREQTRGFEVIRNG
MAB_1336|M.abscessus_ATCC_1997 MALELAGDPIALTAALVDIPSESRHEAQIADAVEVALREQTSGFEVIRNG
*:* .**: *****:**** ** * ::** :*.*** *: **::***
Mb1234|M.bovis_AF2122/97 NAVLARTKLNRSSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSG
Rv1202|M.tuberculosis_H37Rv NAVLARTKLNRSSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSG
MMAR_4235|M.marinum_M NAVLARTRLNRPSRVLLAGHLDTVPVADNLPSRRADGQLHGCGAADMKSG
MUL_0954|M.ulcerans_Agy99 NAVLARTRLNRPSRVLLAGHLDTVPVADNLPSRRADGQLHGCGAADMKSG
MLBr_01059|M.leprae_Br4923 NAVLARTSLHRPARVLLAGHLDTVPVAGNLPSRCEKDVLHGCGTVDMKSG
MAV_1349|M.avium_104 NAVLARTDRGRPSRVLLAGHLDTVPVAGNLPSRREDGDLYGCGTADMKSG
Mvan_4515|M.vanbaalenii_PYR-1 DAVLARTDFGRPSRVLLAGHIDTVPAADNLPSRLADGVLHGCGTSDMKAG
Mflv_2180|M.gilvum_PYR-GCK DAVLARTHFGRPSRVLLAGHTDTVPAADNLPSRLADGILHGCGTSDMKSG
MSMEG_5103|M.smegmatis_MC2_155 DAVLARTNLGRPSRVMLAGHIDTVPIADNLPSRIVDGEMYGCGTSDMKAG
TH_1840|M.thermoresistible__bu NAVLARTNHGRPTRVLLAGHTDTVPAADNLPSRRVGDLLYGCGTSDMKSG
MAB_1336|M.abscessus_ATCC_1997 NAVLARTNNGLGTRVMLAGHLDTVPAADNVPSRHEGEILHGCGTVDMKSG
:****** :**:**** **** *.*:*** ::***: ***:*
Mb1234|M.bovis_AF2122/97 DAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADV
Rv1202|M.tuberculosis_H37Rv DAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADV
MMAR_4235|M.marinum_M DAVFLHLAATVAEPVHDLTLVFYDCEEIEAAANGLGRIERELPEWLSADV
MUL_0954|M.ulcerans_Agy99 DAVFLHLAATVAEPVHDLTLVFYDCEEIEAAANGLGRIERELPEWLSADV
MLBr_01059|M.leprae_Br4923 DAVFLHLAATVTEPVHDLTLMFYDCEEIDSAANGLVRIERELPEWLAADV
MAV_1349|M.avium_104 DAVFLHLAATVADPAHDLTLVMYDCEEIDAAANGLGRIQRELPDWLSADV
Mvan_4515|M.vanbaalenii_PYR-1 DAVFLHLAATVAEPAHDITLVMYDCEEIEASANGLGRIERELPEWLAADV
Mflv_2180|M.gilvum_PYR-GCK DAVFLHLAATVVDPAHDITLVMYDCEEIEASANGLGRIERELPEWLAADV
MSMEG_5103|M.smegmatis_MC2_155 DAVFLHLAATITEPTHDITLVMYDCEEIESSANGLGRIERELRDWLTADV
TH_1840|M.thermoresistible__bu DAVFLHLAATVTEPAHDITLVMYDCEEIEAAANGLGRIERELPDWLRADV
MAB_1336|M.abscessus_ATCC_1997 DAVFLHLAATVT-PRVDLTLVFYDCEEIESSANGLGRIERELPDWLDADL
**********:. * *:**::******:::**** **:*** :** **:
Mb1234|M.bovis_AF2122/97 AILGEPTAGCIEAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLD
Rv1202|M.tuberculosis_H37Rv AILGEPTAGCIEAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLD
MMAR_4235|M.marinum_M AILGEPTSGYIEAGCQGTLRVVISATGTRAHSARSWLGDNAIHKLSAVLD
MUL_0954|M.ulcerans_Agy99 AILGEPTSGYIEAGCQGTLRVVISATGTRAHSARSWLGDNAIHKLSAVLD
MLBr_01059|M.leprae_Br4923 AILGEPTGGYIEAGCQGTLRVVINAAGSRAHSARSWLGDNAIHKLGAVLD
MAV_1349|M.avium_104 AILGEPTGGYIEAGCQGTLRVVVSATGTRAHSARSWLGDNAIHKLGAVLQ
Mvan_4515|M.vanbaalenii_PYR-1 AILGEPSGGLIEAGCQGTLRVIVRATGTRAHSARSWLGDNAIHKLSDVLA
Mflv_2180|M.gilvum_PYR-GCK AILGEPSGGYIEAGCQGTLRVVVRATGTRAHSARSWLGDNAVHKLGDVLA
MSMEG_5103|M.smegmatis_MC2_155 AILGEPSGGYIEAGCQGTIRVVISAKGTRAHSARSWLGDNAIHKLAPVLD
TH_1840|M.thermoresistible__bu AILGEPSGGFIEAGCQGTLRMVISTTGTRAHSARSWLGDNAIHKLAPVLD
MAB_1336|M.abscessus_ATCC_1997 AILGEPTAGLIEAGCQGTLRVVIRTRGTRAHSARSWLGDNAIHKLAAVLD
******:.* ********:*::: . *:*************:***. **
Mb1234|M.bovis_AF2122/97 RLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASVTINYRFAPD
Rv1202|M.tuberculosis_H37Rv RLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASVTINYRFAPD
MMAR_4235|M.marinum_M RLARYPARSVDIDGCTYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAPD
MUL_0954|M.ulcerans_Agy99 RLARYPARSVDIDGCTYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAPD
MLBr_01059|M.leprae_Br4923 RLAAYRARTVDIDGCVYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAPD
MAV_1349|M.avium_104 RLAGYQARSVEIDGCTYREGLSAVRIDGGVAGNVIPDAAAVTVNFRFAPD
Mvan_4515|M.vanbaalenii_PYR-1 RLRSYQARSVDIDGCVYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAPD
Mflv_2180|M.gilvum_PYR-GCK RLTAYRARSVDIDGCTYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAPD
MSMEG_5103|M.smegmatis_MC2_155 RLASYQARSVDIDGCVYREGLSAVRIDGGIAGNVIPDAASVTVNFRFAPD
TH_1840|M.thermoresistible__bu RLSDYRARSVDIDGCVYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAPD
MAB_1336|M.abscessus_ATCC_1997 RLAAYRARIVDIDGCQYREGLSAVRIDGGVAGNVIPDEAAVTVNFRFAPD
** * ** *:**** *********: **:******* *:**:*:*****
Mb1234|M.bovis_AF2122/97 RSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQV
Rv1202|M.tuberculosis_H37Rv RSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQV
MMAR_4235|M.marinum_M RSVPAALQHVREVFDGLDVQIEQTDAAAGALPGLAQPAAKALVEAAGGQV
MUL_0954|M.ulcerans_Agy99 RSVPAALQHVREVFDGLDVQIEQTDAAAGALPGLAQPAAKALVEAAGGQV
MLBr_01059|M.leprae_Br4923 RSVAAALRHVHDVFDGLDVQIEQTDAAVGALPGLSQPAAKALVEAADGQV
MAV_1349|M.avium_104 RSPAEALQHVRDVLDGLDVRIEQTDAAAGALPGLSQPAAKALVEAAGGRV
Mvan_4515|M.vanbaalenii_PYR-1 RSVEQAYAHVREVFDRLDVTIELTDAAAGALPGLTRPAAAALVEAAGGQV
Mflv_2180|M.gilvum_PYR-GCK RTIEQAHAHVLEVFDGLDVEIELTDSAAGALPGLSRPAAAALVEAAGGQV
MSMEG_5103|M.smegmatis_MC2_155 RDVDQAVAHVHEVFDGLDVTLELTDAAAGALPGLTQPAAAALVAAAGGQV
TH_1840|M.thermoresistible__bu RTVEQAERHVREVFDGLDVRMELTDAAGGALPGLQQPAAAQLVAAAGGQV
MAB_1336|M.abscessus_ATCC_1997 RSPEQALVHVHEVFDGLDVQIELTDSAAGALPGLDRPAAAELVGAAGGVV
* * ** :*:* *** :* **:* ****** .*** ** **.* *
Mb1234|M.bovis_AF2122/97 RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLR
Rv1202|M.tuberculosis_H37Rv RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLR
MMAR_4235|M.marinum_M RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVATITTVADTLR
MUL_0954|M.ulcerans_Agy99 RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVATITTVADTLR
MLBr_01059|M.leprae_Br4923 RAKYGWTDVSRFAALGVPAVNYGPGDPNLAHRHDERVPVVQITAAVDMLR
MAV_1349|M.avium_104 RAKYGWTDVARFAALGIPALNFGPGDPNLAHRRDERVAVAAITAAADLLR
Mvan_4515|M.vanbaalenii_PYR-1 RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHRVDESVDVAQITAVTDMLR
Mflv_2180|M.gilvum_PYR-GCK RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHRVDEHVEVAQITAVTDMLR
MSMEG_5103|M.smegmatis_MC2_155 RAKYGWTDVARFAALGIPAVNYGPGDPNLAHRVDERVQVAAITAAADMLR
TH_1840|M.thermoresistible__bu RAKYGWTDVARFAALGVPAVNYGPGDPNLAHKSDEHVDVTAITAVTDVLR
MAB_1336|M.abscessus_ATCC_1997 RAKYGWTDVSRFAARGIAAVNYGPGDPNLAHTRGEHVPVQQITAVTEVLR
*********:**** *:.*:*:********* .* * * **:..: **
Mb1234|M.bovis_AF2122/97 RYLGG
Rv1202|M.tuberculosis_H37Rv RYLGG
MMAR_4235|M.marinum_M RYLST
MUL_0954|M.ulcerans_Agy99 RYLST
MLBr_01059|M.leprae_Br4923 RYLGG
MAV_1349|M.avium_104 GYLSG
Mvan_4515|M.vanbaalenii_PYR-1 RYLIG
Mflv_2180|M.gilvum_PYR-GCK RYLIG
MSMEG_5103|M.smegmatis_MC2_155 TYLTT
TH_1840|M.thermoresistible__bu RYLSG
MAB_1336|M.abscessus_ATCC_1997 RYLTV
**