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KKVFAVALGILTAIGGFLDIGDLVTNAVVGSRFGLALVWVVVVGVVGICLFAQMAGRVAAVSGRATFEII RERLGPRTAAANLGASFFINLMTLTAEIGGIALALQLATDVGPMMWIPVAAFAVWLVIWRVKFSVMENAT GILGLCLIVFAVSVFALQPNWGDLAGQAVQPAIPESESAATYWYYAIALFGAAMTPYEVFFFSSGAVEEH WTTKDLGVSRMNVMVGFPLGGLLSIAIATCATLVLLPQQVEVTSLSQVVMPVVEAGGKLALAFAVIGIVA ATFGAALETTLSSGYTLAQFLGWPWGKFRRPAQAARFHVVMFVSIVVGAAVLFTGVDPVLVTEYSVVFSA IALPLTYLPILIVANDPEYMGENTNGKVTNMFGTIYLVIILAASLAAIPLMIVTGAGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1780 | - | - | 100% (409) | hypothetical protein MSMEG_1780 |
| M. smegmatis MC2 155 | MSMEG_5589 | - | 6e-19 | 26.65% (379) | manganese transport protein MntH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0948c | mntH | 5e-19 | 23.33% (403) | putative manganese transport protein MntH |
| M. gilvum PYR-GCK | Mflv_1822 | - | 3e-22 | 25.87% (402) | Mn2+/Fe2+ transporter |
| M. tuberculosis H37Rv | Rv0924c | mntH | 5e-19 | 23.33% (403) | manganese transport protein MntH |
| M. leprae Br4923 | MLBr_02667 | - | 2e-21 | 23.12% (398) | putative membrane transport protein |
| M. abscessus ATCC 19977 | MAB_2716c | - | 5e-26 | 25.00% (400) | manganese transport transmembrane protein |
| M. marinum M | MMAR_4584 | mntH | 1e-20 | 23.62% (398) | divalent cation-transport integral membrane protein MntH |
| M. avium 104 | MAV_2120 | - | 5e-26 | 26.25% (419) | Mn2+/Fe2+ transporter |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4445 | mntH | 1e-20 | 23.62% (398) | manganese transport protein MntH |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2716c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2120|M.avium_104 --------------------------------------------------
MLBr_02667|M.leprae_Br4923 --------------------------------------------------
MSMEG_1780|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 GVQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLCGP
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2716c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2120|M.avium_104 --------------------------------------------------
MLBr_02667|M.leprae_Br4923 --------------------------------------------------
MSMEG_1780|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 IWLGDNSSVMKRVIERLYACSSLLNEDGQYAYYGRAGGCLITGNEDGVKH
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2716c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2120|M.avium_104 --------------------------------------------------
MLBr_02667|M.leprae_Br4923 --------------------------------------------------
MSMEG_1780|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 CAMNVLYSLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDFTNRN
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2716c|M.abscessus_ATCC_199 ---------------------------------------------MSENG
MAV_2120|M.avium_104 ---------------------------------------------MS---
MLBr_02667|M.leprae_Br4923 ---------------------------------------------MSLII
MSMEG_1780|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 TTFMTFNLMHIAQMLRAPAASRPTAINAPSGTPAAGRTSPTPTTDSQRRS
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2716c|M.abscessus_ATCC_199 IVNGSVNGSVNGAETANGQLKVQVSQP-----------------------
MAV_2120|M.avium_104 ----------SGGE--NTRRAEPVEPR-----------------------
MLBr_02667|M.leprae_Br4923 FEHEPVDNSENPMTYISTDAISAVAVPPTTGDAIMCVKNCATPRVTPDTS
MSMEG_1780|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
MUL_4445|M.ulcerans_Agy99 --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
Mb0948c|M.bovis_AF2122/97 RVARWLVAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
Rv0924c|M.tuberculosis_H37Rv ------MAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
Mflv_1822|M.gilvum_PYR-GCK --------------------------MTGDVRPQAKR-WLLLGPAFVAAI
MAB_2716c|M.abscessus_ATCC_199 KSAVLDSAHLGDIEGAFGKISVSDPGQARTFRSRMATMAAILGPGIIVMV
MAV_2120|M.avium_104 GTAVLDSAHLGDIEGAFGRIRVGETEHARTWKTRLLTLLAIVGPGIIVMV
MLBr_02667|M.leprae_Br4923 GSSVLDSAHVGDIVGAFGRIGWDVTHASRSRWQQLRLMMVITGPGLIAMI
MSMEG_1780|M.smegmatis_MC2_155 ----------------------------------MKKVFAVALGILTAIG
: : .
MMAR_4584|M.marinum_M AYVDPGNVAANVSSGAQFGYLLLWVIVVANVMAGLVQYLSAKLGLVTGHS
MUL_4445|M.ulcerans_Agy99 AYVDPGNVAANVSSGAQFGYLLLWVIVVANVMAGLVQYLSAKLGLVTGHS
Mb0948c|M.bovis_AF2122/97 AYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRS
Rv0924c|M.tuberculosis_H37Rv AYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRS
Mflv_1822|M.gilvum_PYR-GCK AYVDPGNVAANVSAGAQFGFLLVWVIVAANLMACLVQYLSAKLGLVTGRS
MAB_2716c|M.abscessus_ATCC_199 GDNDAGGVATYAQAGQSYGYSLLWVLLLLIPVLIVNQEMVVRLGAVTGVG
MAV_2120|M.avium_104 GDNDAGGVATYAQAGQNYGYSLLWVLLLLVPVLIVNQEMVVRLGAVTGVG
MLBr_02667|M.leprae_Br4923 GDNDAGGVATYAQAGQKYGMNLLWTLVLLIPVLYVNQEMVLRLGAVTRVG
MSMEG_1780|M.smegmatis_MC2_155 GFLDIGDLVTNAVVGSRFGLALVWVVVVGVVGICLFAQMAGRVAAVSGRA
. * *.:.: . * :* *:*.:: : : ::. *: .
MMAR_4584|M.marinum_M LPEQIGKRMGRPARLTYWVQAEIVAIATDVAEVVGGAIALRILFGLPLPI
MUL_4445|M.ulcerans_Agy99 LPEQIGKRMGRPARLTYWVQAEIVAIATDMAEVVGGAIALRILFGLPLPI
Mb0948c|M.bovis_AF2122/97 LPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPI
Rv0924c|M.tuberculosis_H37Rv LPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPI
Mflv_1822|M.gilvum_PYR-GCK LPEAVGSRMSRRTRLAYWVQAELVAMATDLAEVVGGAIALYLLFDLPLLV
MAB_2716c|M.abscessus_ATCC_199 HARLINERFGRGWGWFSVGDLFILNFLTLVTEFIGVALASEYLG----VS
MAV_2120|M.avium_104 HARLINERFGRGWGWFSVGDLFLLNFLTIVTEFIGISLAAEYIG----VS
MLBr_02667|M.leprae_Br4923 HARLIFERFGKFWGAFSVGDLLILNALTIVTEFIGVSLALDFLG----CP
MSMEG_1780|M.smegmatis_MC2_155 TFEIIRERLGPRTAAANLGASFFINLMTLTAEIGGIALALQLATD---VG
. : .*:. :: * :*. * ::*
MMAR_4584|M.marinum_M GGIITGVISLLLLLIQDRRGQLLFERVITGLLLIIAVGFTASFFVATPPP
MUL_4445|M.ulcerans_Agy99 GGIITGVISLLLLLIQDRRGQLLFERVITGLLLIIAVGFTASFFVATPPP
Mb0948c|M.bovis_AF2122/97 GGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVVTPPP
Rv0924c|M.tuberculosis_H37Rv GGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVVTPPP
Mflv_1822|M.gilvum_PYR-GCK GGIITGAVSLILLMVKDLRGQRVFERVITGLLMVIAIGFLTSLFAASPPV
MAB_2716c|M.abscessus_ATCC_199 KYYTVPLAAIALILIMATGSFRRWERAMF-VFIAITLLQIPMFLLAEPQW
MAV_2120|M.avium_104 KYVVVPVSAVALVAIMASGSFRRWERAMF-IFIAITLLQIPMLLMSHPQW
MLBr_02667|M.leprae_Br4923 KTIAIPVAAVLLFAMVAGGSFRRWEQVMF-MLISVNVAVIPLVLSVHPAL
MSMEG_1780|M.smegmatis_MC2_155 PMMWIPVAAFAVWLVIWRVKFSVMENATGILGLCLIVFAVSVFALQPNWG
:. : : *.. : : : : . .
MMAR_4584|M.marinum_M DAMFTGLVPHFQGTES------VLLAAAILGATVMPHAVYLHSGLARDRH
MUL_4445|M.ulcerans_Agy99 DAMFTGLVPHFQGTES------VLLAAAILGATVMPHAVYLHSGLARDRH
Mb0948c|M.bovis_AF2122/97 NAVLGGLAPRFQGTES------VLLAAAIMGATVMPHAVYLHSGLARDRH
Rv0924c|M.tuberculosis_H37Rv NAVLGGLAPRFQGTES------VLLAAAIMGATVMPHAVYLHSGLARDRH
Mflv_1822|M.gilvum_PYR-GCK GAAAEGLIPRFDGAES------VLLAAAMLGATVMPHAVYLHSGLARDRH
MAB_2716c|M.abscessus_ATCC_199 GRAAHDFV--VPGIDGGVSSGAVLLIIAMVGTTVAPWQLFFQQSNIVDKR
MAV_2120|M.avium_104 GRAAKSFV--VPSISGGVSSDAVLLIIAIVGTTVAPWQLFFQQSNVVDKR
MLBr_02667|M.leprae_Br4923 GPSLHGLLPSLPGKPDSPTSVVLLVIMAIVGTTVAPWQLFFQQSSVVDKR
MSMEG_1780|M.smegmatis_MC2_155 DLAGQAVQPAIPESES--AATYWYYAIALFGAAMTPYEVFFFSSGAVEEH
. . . . *:.*::: * ::: .. :.:
MMAR_4584|M.marinum_M GHPEPGPYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAALNLQGR-----
MUL_4445|M.ulcerans_Agy99 GHPEPGPYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAALNLQGR-----
Mb0948c|M.bovis_AF2122/97 GHPDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGR-----
Rv0924c|M.tuberculosis_H37Rv GHPDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGR-----
Mflv_1822|M.gilvum_PYR-GCK GHPGPGEPRRALLRITRWDVGIAMLVAGAVNLSMLLVAATNLQGM-----
MAB_2716c|M.abscessus_ATCC_199 ITP-------RFIGYERADTVIGSLVVVIGAAALLMTADYAARATGNSGP
MAV_2120|M.avium_104 ITP-------RFMGYERADTVLGAFVVVIGAAALVMTGDWAARST-----
MLBr_02667|M.leprae_Br4923 ITP-------RWMRYGRADLVVGIVGVMAGAIALMSATAFGLAGT-----
MSMEG_1780|M.smegmatis_MC2_155 WTT-------KDLGVSRMNVMVGFPLGGLLSIAIATCATLVLLPQ-----
. : * : :. ::
MMAR_4584|M.marinum_M ---EDTASIEGAYAAVHDTLGATIAVLFAIGLLASGLASTSVG------A
MUL_4445|M.ulcerans_Agy99 ---EDTASIEGAYAAVHDTLGATIAVLFAIGLLASGLASTSVG------A
Mb0948c|M.bovis_AF2122/97 ---GDTASIEGAYHAVHDTLGATIAVLFAVGLLASGLASSSVG------A
Rv0924c|M.tuberculosis_H37Rv ---GDTASIEGAYHAVHDTLGATIAVLFAVGLLASGLASSSVG------A
Mflv_1822|M.gilvum_PYR-GCK ---ADTDSIEGAHAAVQNTLGDTVALLFAIGLLASGLASSSVG------A
MAB_2716c|M.abscessus_ATCC_199 DKWGDSGDAGLIAEWLG-QVQPLLGKIFAIVLLDASIIGAAAVTLATSYA
MAV_2120|M.avium_104 DTVGGFTDAGATAHLLG-QHRQVLGSIFAIVLMDASIIGAAAVTLATSYA
MLBr_02667|M.leprae_Br4923 ADSGNFTDAGAVASHLSDHVGHPIGVLFAIILLDASLIGANVVGLATTYA
MSMEG_1780|M.smegmatis_MC2_155 --QVEVTSLSQVVMPVVEAGGKLALAFAVIGIVAATFGAALETTLSSGYT
. : : .: :: : : .: :
MMAR_4584|M.marinum_M YAGAMIMQGLLHWSVP-----MAVRRLVTLCPAVAILALGLDPTRTLVLS
MUL_4445|M.ulcerans_Agy99 YAGAMIMQGLLHWSVP-----MAVRRLVTLCPAVAILALGLDPTRTLVLS
Mb0948c|M.bovis_AF2122/97 YAGAMIMQGLLHWSVP-----MLVRRLITLGPALAILTLGFDPTRTLVLS
Rv0924c|M.tuberculosis_H37Rv YAGAMIMQGLLHWSVP-----MLVRRLITLGPALAILTLGFDPTRTLVLS
Mflv_1822|M.gilvum_PYR-GCK YAGAMIMQGLLRRSVP-----LLARRLITLLPALVILAVGIHPSRALVLS
MAB_2716c|M.abscessus_ATCC_199 FGDTFGLKHSLHRSFKDAKPFYLSYTVMVGVGAAIVLIPNAPLGLMTTAV
MAV_2120|M.avium_104 FGDVFGLKHSLHRGFADAKQFYLSYTAMVVVAAAIVLIPGAPLGLITTAV
MLBr_02667|M.leprae_Br4923 LGDALGKPHSLHWKITEAPLFYGSYTALLGISAVVAFSPGHILGLITQGV
MSMEG_1780|M.smegmatis_MC2_155 LAQFLGWPWGKFRRPAQAAR-FHVVMFVSIVVGAAVLFTGVDPVLVTEYS
. : : . : .
MMAR_4584|M.marinum_M QVVLSFGIPFAVLPLVRLTSNPEVMGSDTNHRLTTWIGWGVAVLISVLNV
MUL_4445|M.ulcerans_Agy99 QVVLSFGIPFAVLPLVRLTSNPEVMGSDTNHRLTTWIGWGVAVLISVLNV
Mb0948c|M.bovis_AF2122/97 QVVLSFGIPFAVLPLVKLTGSPAVMGGDTNHRATTWVGWVVAVMVSLLNV
Rv0924c|M.tuberculosis_H37Rv QVVLSFGIPFAVLPLVKLTGSPAVMGGDTNHRATTWVGWVVAVMVSLLNV
Mflv_1822|M.gilvum_PYR-GCK QVVLSFGIPFALIPLVRLTADRALMGADVNHRVTTAAGWVVAGLISLLNV
MAB_2716c|M.abscessus_ATCC_199 QALAGLLLPSASVFLLLLCNDKAVLGPWVNKPWLNIVAGLIVGVLLFLSG
MAV_2120|M.avium_104 QALAGLLLPSASVFLLLLCNDREVLGPWVNRAWLNWVAGLIVGTLLLLSG
MLBr_02667|M.leprae_Br4923 QALAGVLLPSATVFLVLLCNDRPVLGPWVNTARQNVFAWMIVWSLVVLSL
MSMEG_1780|M.smegmatis_MC2_155 VVFSAIALPLTYLPILIVANDPEYMGENTNGKVTNMFGTIYLVIILAASL
.. .. :* : : :: : . :* .* . . : .
MMAR_4584|M.marinum_M ALIYLTLTG-----------------------------------------
MUL_4445|M.ulcerans_Agy99 ALIYLTLTG-----------------------------------------
Mb0948c|M.bovis_AF2122/97 MLIYLTVTG-----------------------------------------
Rv0924c|M.tuberculosis_H37Rv MLIYLTVTG-----------------------------------------
Mflv_1822|M.gilvum_PYR-GCK VLIYLTLWG-----------------------------------------
MAB_2716c|M.abscessus_ATCC_199 ILMATTLFPDLDVVEVARDLAVGVTILAVLIGTGLW--WVSSRQRAD---
MAV_2120|M.avium_104 ILMATTLFPDLNVVAVAGYLTLALIILAAGAAPVLR--WLARRQPAR---
MLBr_02667|M.leprae_Br4923 MLTVVTLFPNLSTAAMVGGLGAGTALGVVGAAAVIVAGWLAERRGAGGIA
MSMEG_1780|M.smegmatis_MC2_155 AAIPLMIVTGAGQ-------------------------------------
:
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 --------------------------------------------------
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2716c|M.abscessus_ATCC_199 --PAV---------------LAMTKVLDGVDARTWRMPPLALLEPVRWSP
MAV_2120|M.avium_104 --PGP---------------RLPAR---GVDRSTWRMPPLTLLEPVTWSP
MLBr_02667|M.leprae_Br4923 QQPSCSGSEQAQFDALARLTRAERRALCDERRANWTMPVLANLDRPVMSP
MSMEG_1780|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_4584|M.marinum_M -------------------------------
MUL_4445|M.ulcerans_Agy99 -------------------------------
Mb0948c|M.bovis_AF2122/97 -------------------------------
Rv0924c|M.tuberculosis_H37Rv -------------------------------
Mflv_1822|M.gilvum_PYR-GCK -------------------------------
MAB_2716c|M.abscessus_ATCC_199 GTKLGMLALRGYLVVGAILLVVKAIQLAHGN
MAV_2120|M.avium_104 GTRLAMIALRGYLVVGALLLVVKAIQLSR--
MLBr_02667|M.leprae_Br4923 VRRIGLLMLRGYLVLACVLVVVKVVQVGVG-
MSMEG_1780|M.smegmatis_MC2_155 -------------------------------