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M. bovis AF2122 / 97 Mb0948c (mntH)

annotation: putative manganese transport protein MntH
coordinates: 1031044 - 1033098
length: 684

MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREHGVQVDTLRAVDHDIATGVWP
DMTEHGWATDEWPALYRRVLDAHILVLCGPIWLGDNSSVMKRVIERLYACSSLLNEDGQYAYYGRAGGCL
ITGNEDGVKHCAMNVLYSLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDFTNRNTTFMTFNLMH
IAQMLRAPAASRPTAINAPSGTPAAGRTSPTPTTDSQRRSRVARWLVAGEFRLLSHLCSRGSKVGELAQD
TRTSLKTSWYLLGPAFVAAIAYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRS
LPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPIGGIITGVVSLLLLTIQDRRG
QRLFERVITALLLVIAIGFTASFFVVTPPPNAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLA
RDRHGHPDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTASIEGAYHAVHDTLGATI
AVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWSVPMLVRRLITLGPALAILTLGFDPTRTLVLSQVVLS
FGIPFAVLPLVKLTGSPAVMGGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0948cmntH-100% (684)putative manganese transport protein MntH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1822-1e-16773.83% (405) Mn2+/Fe2+ transporter
M. tuberculosis H37RvRv0924cmntH0.0100.00% (428) manganese transport protein MntH
M. leprae Br4923MLBr_02098mntH1e-17274.82% (413) manganese transport protein MntH
M. abscessus ATCC 19977MAB_1031c-1e-15871.17% (392) manganese transport protein MntH
M. marinum MMMAR_4584mntH0.086.52% (408) divalent cation-transport integral membrane protein MntH
M. avium 104MAV_1044-1e-17878.43% (408) manganese transport protein MntH
M. smegmatis MC2 155MSMEG_5589-1e-16672.66% (406) manganese transport protein MntH
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4445mntH0.086.27% (408) manganese transport protein MntH
M. vanbaalenii PYR-1Mvan_4745-6e-2437.28% (169) hypothetical protein Mvan_4745

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1822|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02098|M.leprae_Br4923          --------------------------------------------------
MAV_1044|M.avium_104                --------------------------------------------------
MMAR_4584|M.marinum_M               --------------------------------------------------
MUL_4445|M.ulcerans_Agy99           --------------------------------------------------
Rv0924c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0948c|M.bovis_AF2122/97           MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
Mvan_4745|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1822|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02098|M.leprae_Br4923          --------------------------------------------------
MAV_1044|M.avium_104                --------------------------------------------------
MMAR_4584|M.marinum_M               --------------------------------------------------
MUL_4445|M.ulcerans_Agy99           --------------------------------------------------
Rv0924c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0948c|M.bovis_AF2122/97           GVQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLCGP
Mvan_4745|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1822|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02098|M.leprae_Br4923          --------------------------------------------------
MAV_1044|M.avium_104                --------------------------------------------------
MMAR_4584|M.marinum_M               --------------------------------------------------
MUL_4445|M.ulcerans_Agy99           --------------------------------------------------
Rv0924c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0948c|M.bovis_AF2122/97           IWLGDNSSVMKRVIERLYACSSLLNEDGQYAYYGRAGGCLITGNEDGVKH
Mvan_4745|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1822|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02098|M.leprae_Br4923          --------------------------------------------------
MAV_1044|M.avium_104                --------------------------------------------------
MMAR_4584|M.marinum_M               --------------------------------------------------
MUL_4445|M.ulcerans_Agy99           --------------------------------------------------
Rv0924c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0948c|M.bovis_AF2122/97           CAMNVLYSLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDFTNRN
Mvan_4745|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1822|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02098|M.leprae_Br4923          --------------------------------------------------
MAV_1044|M.avium_104                --------------------------------------------------
MMAR_4584|M.marinum_M               --------------------------------------------------
MUL_4445|M.ulcerans_Agy99           --------------------------------------------------
Rv0924c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0948c|M.bovis_AF2122/97           TTFMTFNLMHIAQMLRAPAASRPTAINAPSGTPAAGRTSPTPTTDSQRRS
Mvan_4745|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1822|M.gilvum_PYR-GCK          -------------------------MTGDVR-PQAKR-WLLLGPAFVAAI
MSMEG_5589|M.smegmatis_MC2_155      -------------------------MLEDTK-VRARPSWLLLGPAFVAAI
MAB_1031c|M.abscessus_ATCC_199      -------------------------MLERQKQARPLRGLSLLGPAFVAAI
MLBr_02098|M.leprae_Br4923          --------MFVNLTCLSEGNGSRGKALAESTQAELKTSWYLLGPAFVAAI
MAV_1044|M.avium_104                --------------------------MAQRTQGSLKGNWYLLGPAFVAAI
MMAR_4584|M.marinum_M               --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
MUL_4445|M.ulcerans_Agy99           --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
Rv0924c|M.tuberculosis_H37Rv        ------MAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
Mb0948c|M.bovis_AF2122/97           RVARWLVAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
Mvan_4745|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1822|M.gilvum_PYR-GCK          AYVDPGNVAANVSAGAQFGFLLVWVIVAANLMACLVQYLSAKLGLVTGRS
MSMEG_5589|M.smegmatis_MC2_155      AYVDPGNVAANVSAGAQYGFLLVWVIVVANVMAGLVQYLSAKLGLVTGRS
MAB_1031c|M.abscessus_ATCC_199      AYVDPGNVASNVSAGAKYGFLLVWVIVTANVMAGLVQYLSAKLGLVTGQS
MLBr_02098|M.leprae_Br4923          AYVDPGNVAANVSSGAQFGYLQLWVVVVANVLAGLVQYLSAKLGLVTGQS
MAV_1044|M.avium_104                AYVDPGNVAANVSAGSQYGYLLLWVIVAANVLAGLVQYLSAKLGLVTGRS
MMAR_4584|M.marinum_M               AYVDPGNVAANVSSGAQFGYLLLWVIVVANVMAGLVQYLSAKLGLVTGHS
MUL_4445|M.ulcerans_Agy99           AYVDPGNVAANVSSGAQFGYLLLWVIVVANVMAGLVQYLSAKLGLVTGHS
Rv0924c|M.tuberculosis_H37Rv        AYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRS
Mb0948c|M.bovis_AF2122/97           AYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRS
Mvan_4745|M.vanbaalenii_PYR-1       --------------------------------------------------
                                                                                      

Mflv_1822|M.gilvum_PYR-GCK          LPEAVGSRMSRRTRLAYWVQAELVAMATDLAEVVGGAIALYLLFDLPLLV
MSMEG_5589|M.smegmatis_MC2_155      LPEAVADHTRTPTRVAFWLQAELVAMATDLAEVVGGAIALYLLFDLPLLV
MAB_1031c|M.abscessus_ATCC_199      LPEAIGDRMARPTRLTFWLQAELVAMATDLAEVVGGAIALHLLFGLPLLL
MLBr_02098|M.leprae_Br4923          LPQAISKQMSHPFRLGFWLQAELVAMATDVAEIVGGAIAFHILFRVSLLL
MAV_1044|M.avium_104                LPATIGKRMSRPARLVYWVQAELVAIATDAAEVVGGAIALHILFGLPLLA
MMAR_4584|M.marinum_M               LPEQIGKRMGRPARLTYWVQAEIVAIATDVAEVVGGAIALRILFGLPLPI
MUL_4445|M.ulcerans_Agy99           LPEQIGKRMGRPARLTYWVQAEIVAIATDMAEVVGGAIALRILFGLPLPI
Rv0924c|M.tuberculosis_H37Rv        LPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPI
Mb0948c|M.bovis_AF2122/97           LPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPI
Mvan_4745|M.vanbaalenii_PYR-1       -------------------------MAENAIPVR----ALGLICSLKPSP
                                                             :* :   :     *: ::  :    

Mflv_1822|M.gilvum_PYR-GCK          GGIITGAVSLILLMVKDLRGQRVFERVITGLLMVIAIGFLTSLFAASPPV
MSMEG_5589|M.smegmatis_MC2_155      GGLITGVVSLLLLAVQNRRGQRVFERVITGLLMVIAIGFLTSLFVKTPPA
MAB_1031c|M.abscessus_ATCC_199      GGVITGIVSMALLTVQDRRGQRSFEYVISALLAIIAIGFLASVVVEPPPL
MLBr_02098|M.leprae_Br4923          GGVITGTVSLLLLMVKDRRGQLLFERVITGLLFVIVVGFTSSFFVATPSP
MAV_1044|M.avium_104                GGLITGVVALLLLGIQDRRGQILFERVITGLLLVIAIGFAASFFVKTAPP
MMAR_4584|M.marinum_M               GGIITGVISLLLLLIQDRRGQLLFERVITGLLLIIAVGFTASFFVATPPP
MUL_4445|M.ulcerans_Agy99           GGIITGVISLLLLLIQDRRGQLLFERVITGLLLIIAVGFTASFFVATPPP
Rv0924c|M.tuberculosis_H37Rv        GGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVVTPPP
Mb0948c|M.bovis_AF2122/97           GGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVVTPPP
Mvan_4745|M.vanbaalenii_PYR-1       APSSSALIAEHVFETLREQG--------AECEAVRCVDFN------IAPG
                                    .   :. ::  ::     :*        :    :  :.*        .. 

Mflv_1822|M.gilvum_PYR-GCK          GAAAEGLIPRFDGAESVLLAAAMLGATVMPHAVYLHSGLARDRHGHPGPG
MSMEG_5589|M.smegmatis_MC2_155      AAVADGLIPRFDGAESILLATAMLGATVMPHAVYLHSGLARDRHGHAE-G
MAB_1031c|M.abscessus_ATCC_199      PEAAAGLIPHFQGTESLLLATAMLGATVMPHAVYLHSGLTRDRHGRPAEG
MLBr_02098|M.leprae_Br4923          EDMVNGLLPRFQGTESVLLAAAIIGATVMPHAVYLHSGLALDRHGHPHAG
MAV_1044|M.avium_104                EAVLSGLLPRFRGTESVLLAAAILGATVMPHAVYMHSGLVLDRHGHPDEG
MMAR_4584|M.marinum_M               DAMFTGLVPHFQGTESVLLAAAILGATVMPHAVYLHSGLARDRHGHPEPG
MUL_4445|M.ulcerans_Agy99           DAMFTGLVPHFQGTESVLLAAAILGATVMPHAVYLHSGLARDRHGHPEPG
Rv0924c|M.tuberculosis_H37Rv        NAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLARDRHGHPDPG
Mb0948c|M.bovis_AF2122/97           NAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLARDRHGHPDPG
Mvan_4745|M.vanbaalenii_PYR-1       VEADMGDSDQWPQIRQKVLAADIL---LISTPVWLG---------HPSSV
                                         *   ::   .. :**: ::   ::. .*::          :.   

Mflv_1822|M.gilvum_PYR-GCK          EPRRALLRITRWDVGIAMLVAGAVNLSMLLVAATNLQGMADTDSIEGAHA
MSMEG_5589|M.smegmatis_MC2_155      PRLRMLLRVTRFDVGLAMLVAGAVNMAMLLVAATNLQGRGDTDSIEGAHA
MAB_1031c|M.abscessus_ATCC_199      EPRRRLLRITRWDVCLAMVFAGAVNMAMLLAAATNLRGRDGVDTIEGAHA
MLBr_02098|M.leprae_Br4923          RSRRRLLRVTRLDVILAMTIAGIVNTAMLLVAAINLQHHQVTAYIEGTYT
MAV_1044|M.avium_104                PHRRLLLRVTRWDVVLAMAVAGTVNAAMLLIAATNLQHRDVSASIEGAYA
MMAR_4584|M.marinum_M               PYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAALNLQGREDTASIEGAYA
MUL_4445|M.ulcerans_Agy99           PYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAALNLQGREDTASIEGAYA
Rv0924c|M.tuberculosis_H37Rv        PQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTASIEGAYH
Mb0948c|M.bovis_AF2122/97           PQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTASIEGAYH
Mvan_4745|M.vanbaalenii_PYR-1       TQR----VLERLDAELSNTDDQGRPAMAGKVAIVSVVGNE-----DGAHK
                                            : * *. ::              *  .:         :*:: 

Mflv_1822|M.gilvum_PYR-GCK          AVQNTLGDTVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSVPLLAR
MSMEG_5589|M.smegmatis_MC2_155      AVSDALGPTVALLFAIGLLASGLASTSVGAYAGAMIMQGLLKKSYPLLLR
MAB_1031c|M.abscessus_ATCC_199      AVRDSLGPTVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSIPIVAR
MLBr_02098|M.leprae_Br4923          AIQDTLGATIAMLFAIGLLASSLASASVGAYAGALIMQGLLQRSIPMLIR
MAV_1044|M.avium_104                AIHNTLGATIAVMFAVGLLASGLASSSVGAYAGAMIMQGLLHRSIPMVVR
MMAR_4584|M.marinum_M               AVHDTLGATIAVLFAIGLLASGLASTSVGAYAGAMIMQGLLHWSVPMAVR
MUL_4445|M.ulcerans_Agy99           AVHDTLGATIAVLFAIGLLASGLASTSVGAYAGAMIMQGLLHWSVPMAVR
Rv0924c|M.tuberculosis_H37Rv        AVHDTLGATIAVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWSVPMLVR
Mb0948c|M.bovis_AF2122/97           AVHDTLGATIAVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWSVPMLVR
Mvan_4745|M.vanbaalenii_PYR-1       VVADVFQG-------LNDVGYSIPAQGCTYWNGPAMES---------TDY
                                    .: : :         :. :. .:.: .   : *. : .            

Mflv_1822|M.gilvum_PYR-GCK          RLITLLPALVILAVGIHPSRALVLSQVVLSFGIPFALIPLVRLTADRALM
MSMEG_5589|M.smegmatis_MC2_155      RLVTLVPALLVLAIGVDPSRALVLSQVVLSFGIPFALIPLVRLTSDKALM
MAB_1031c|M.abscessus_ATCC_199      RLITLLPALAILAAGIDPTRALVISQVVLSFGIPFALIPLIRLTGDRRLM
MLBr_02098|M.leprae_Br4923          RLITLCPAIAILALGFDPTRALVLSQIVLSFGIPFAVLPLVKLTNNRGLM
MAV_1044|M.avium_104                RLITLCPALLILAVGYDTTRALVLSQVVLSFGIPFAVLPLIKLTSDRELM
MMAR_4584|M.marinum_M               RLVTLCPAVAILALGLDPTRTLVLSQVVLSFGIPFAVLPLVRLTSNPEVM
MUL_4445|M.ulcerans_Agy99           RLVTLCPAVAILALGLDPTRTLVLSQVVLSFGIPFAVLPLVRLTSNPEVM
Rv0924c|M.tuberculosis_H37Rv        RLITLGPALAILTLGFDPTRTLVLSQVVLSFGIPFAVLPLVKLTGSPAVM
Mb0948c|M.bovis_AF2122/97           RLITLGPALAILTLGFDPTRTLVLSQVVLSFGIPFAVLPLVKLTGSPAVM
Mvan_4745|M.vanbaalenii_PYR-1       KDLDEVPEQVASTTAAAARNAVRLARVLKQAQYPPY--------------
                                    : :   *     : .  . .:: ::::: .   *                

Mflv_1822|M.gilvum_PYR-GCK          GADVNHRVTTAAGWVVAGLISLLNVVLIYLTLWG
MSMEG_5589|M.smegmatis_MC2_155      GGDANHRVTTAFGWGVAGLISVLNVVLIYLTVNG
MAB_1031c|M.abscessus_ATCC_199      GSDANHRVTTLLGWIIAALISALNVVLIFLTLAN
MLBr_02098|M.leprae_Br4923          GNDTNHPATTVLGWAVAILVSLLNVVLIYLTVTS
MAV_1044|M.avium_104                GSDANHRITTILGWGVGILISLLNMVLIWLTVTG
MMAR_4584|M.marinum_M               GSDTNHRLTTWIGWGVAVLISVLNVALIYLTLTG
MUL_4445|M.ulcerans_Agy99           GSDTNHRLTTWIGWGVAVLISVLNVALIYLTLTG
Rv0924c|M.tuberculosis_H37Rv        GGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
Mb0948c|M.bovis_AF2122/97           GGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
Mvan_4745|M.vanbaalenii_PYR-1       ----------------------------------