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TGDVRPQAKRWLLLGPAFVAAIAYVDPGNVAANVSAGAQFGFLLVWVIVAANLMACLVQYLSAKLGLVTG RSLPEAVGSRMSRRTRLAYWVQAELVAMATDLAEVVGGAIALYLLFDLPLLVGGIITGAVSLILLMVKDL RGQRVFERVITGLLMVIAIGFLTSLFAASPPVGAAAEGLIPRFDGAESVLLAAAMLGATVMPHAVYLHSG LARDRHGHPGPGEPRRALLRITRWDVGIAMLVAGAVNLSMLLVAATNLQGMADTDSIEGAHAAVQNTLGD TVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSVPLLARRLITLLPALVILAVGIHPSRALVLSQVV LSFGIPFALIPLVRLTADRALMGADVNHRVTTAAGWVVAGLISLLNVVLIYLTLWG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1822 | - | - | 100% (407) | Mn2+/Fe2+ transporter |
| M. gilvum PYR-GCK | Mflv_5193 | - | 8e-09 | 21.28% (343) | hypothetical protein Mflv_5193 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0948c | mntH | 1e-167 | 73.83% (405) | putative manganese transport protein MntH |
| M. tuberculosis H37Rv | Rv0924c | mntH | 1e-167 | 73.83% (405) | manganese transport protein MntH |
| M. leprae Br4923 | MLBr_02098 | mntH | 1e-154 | 70.05% (394) | manganese transport protein MntH |
| M. abscessus ATCC 19977 | MAB_1031c | - | 1e-169 | 77.81% (392) | manganese transport protein MntH |
| M. marinum M | MMAR_4584 | mntH | 1e-165 | 74.24% (396) | divalent cation-transport integral membrane protein MntH |
| M. avium 104 | MAV_1044 | - | 1e-161 | 72.98% (396) | manganese transport protein MntH |
| M. smegmatis MC2 155 | MSMEG_5589 | - | 1e-180 | 80.88% (408) | manganese transport protein MntH |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4445 | mntH | 1e-165 | 74.24% (396) | manganese transport protein MntH |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0948c|M.bovis_AF2122/97 MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 GVQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLCGP
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 IWLGDNSSVMKRVIERLYACSSLLNEDGQYAYYGRAGGCLITGNEDGVKH
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 CAMNVLYSLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDFTNRN
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 TTFMTFNLMHIAQMLRAPAASRPTAINAPSGTPAAGRTSPTPTTDSQRRS
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
Mflv_1822|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 RVARWLVAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
Rv0924c|M.tuberculosis_H37Rv ------MAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
MMAR_4584|M.marinum_M --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
MUL_4445|M.ulcerans_Agy99 --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
MAV_1044|M.avium_104 --------------------------MAQRTQGSLKGNWYLLGPAFVAAI
MLBr_02098|M.leprae_Br4923 --------MFVNLTCLSEGNGSRGKALAESTQAELKTSWYLLGPAFVAAI
Mflv_1822|M.gilvum_PYR-GCK -------------------------MTGDVR-PQAKR-WLLLGPAFVAAI
MSMEG_5589|M.smegmatis_MC2_155 -------------------------MLEDTK-VRARPSWLLLGPAFVAAI
MAB_1031c|M.abscessus_ATCC_199 -------------------------MLERQKQARPLRGLSLLGPAFVAAI
**********
Mb0948c|M.bovis_AF2122/97 AYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRS
Rv0924c|M.tuberculosis_H37Rv AYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLVTGRS
MMAR_4584|M.marinum_M AYVDPGNVAANVSSGAQFGYLLLWVIVVANVMAGLVQYLSAKLGLVTGHS
MUL_4445|M.ulcerans_Agy99 AYVDPGNVAANVSSGAQFGYLLLWVIVVANVMAGLVQYLSAKLGLVTGHS
MAV_1044|M.avium_104 AYVDPGNVAANVSAGSQYGYLLLWVIVAANVLAGLVQYLSAKLGLVTGRS
MLBr_02098|M.leprae_Br4923 AYVDPGNVAANVSSGAQFGYLQLWVVVVANVLAGLVQYLSAKLGLVTGQS
Mflv_1822|M.gilvum_PYR-GCK AYVDPGNVAANVSAGAQFGFLLVWVIVAANLMACLVQYLSAKLGLVTGRS
MSMEG_5589|M.smegmatis_MC2_155 AYVDPGNVAANVSAGAQYGFLLVWVIVVANVMAGLVQYLSAKLGLVTGRS
MAB_1031c|M.abscessus_ATCC_199 AYVDPGNVASNVSAGAKYGFLLVWVIVTANVMAGLVQYLSAKLGLVTGQS
*********:***:*:::*:* :**:*.**::* **************:*
Mb0948c|M.bovis_AF2122/97 LPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPI
Rv0924c|M.tuberculosis_H37Rv LPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNLPLPI
MMAR_4584|M.marinum_M LPEQIGKRMGRPARLTYWVQAEIVAIATDVAEVVGGAIALRILFGLPLPI
MUL_4445|M.ulcerans_Agy99 LPEQIGKRMGRPARLTYWVQAEIVAIATDMAEVVGGAIALRILFGLPLPI
MAV_1044|M.avium_104 LPATIGKRMSRPARLVYWVQAELVAIATDAAEVVGGAIALHILFGLPLLA
MLBr_02098|M.leprae_Br4923 LPQAISKQMSHPFRLGFWLQAELVAMATDVAEIVGGAIAFHILFRVSLLL
Mflv_1822|M.gilvum_PYR-GCK LPEAVGSRMSRRTRLAYWVQAELVAMATDLAEVVGGAIALYLLFDLPLLV
MSMEG_5589|M.smegmatis_MC2_155 LPEAVADHTRTPTRVAFWLQAELVAMATDLAEVVGGAIALYLLFDLPLLV
MAB_1031c|M.abscessus_ATCC_199 LPEAIGDRMARPTRLTFWLQAELVAMATDLAEVVGGAIALHLLFGLPLLL
** :..: *: :* ***:**:*** **::*****: ::* :.*
Mb0948c|M.bovis_AF2122/97 GGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVVTPPP
Rv0924c|M.tuberculosis_H37Rv GGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVVTPPP
MMAR_4584|M.marinum_M GGIITGVISLLLLLIQDRRGQLLFERVITGLLLIIAVGFTASFFVATPPP
MUL_4445|M.ulcerans_Agy99 GGIITGVISLLLLLIQDRRGQLLFERVITGLLLIIAVGFTASFFVATPPP
MAV_1044|M.avium_104 GGLITGVVALLLLGIQDRRGQILFERVITGLLLVIAIGFAASFFVKTAPP
MLBr_02098|M.leprae_Br4923 GGVITGTVSLLLLMVKDRRGQLLFERVITGLLFVIVVGFTSSFFVATPSP
Mflv_1822|M.gilvum_PYR-GCK GGIITGAVSLILLMVKDLRGQRVFERVITGLLMVIAIGFLTSLFAASPPV
MSMEG_5589|M.smegmatis_MC2_155 GGLITGVVSLLLLAVQNRRGQRVFERVITGLLMVIAIGFLTSLFVKTPPA
MAB_1031c|M.abscessus_ATCC_199 GGVITGIVSMALLTVQDRRGQRSFEYVISALLAIIAIGFLASVVVEPPPL
**:*** ::: ** ::: *** ** **:.** :*.:** :*... ...
Mb0948c|M.bovis_AF2122/97 NAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLARDRHGHPDPG
Rv0924c|M.tuberculosis_H37Rv NAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLARDRHGHPDPG
MMAR_4584|M.marinum_M DAMFTGLVPHFQGTESVLLAAAILGATVMPHAVYLHSGLARDRHGHPEPG
MUL_4445|M.ulcerans_Agy99 DAMFTGLVPHFQGTESVLLAAAILGATVMPHAVYLHSGLARDRHGHPEPG
MAV_1044|M.avium_104 EAVLSGLLPRFRGTESVLLAAAILGATVMPHAVYMHSGLVLDRHGHPDEG
MLBr_02098|M.leprae_Br4923 EDMVNGLLPRFQGTESVLLAAAIIGATVMPHAVYLHSGLALDRHGHPHAG
Mflv_1822|M.gilvum_PYR-GCK GAAAEGLIPRFDGAESVLLAAAMLGATVMPHAVYLHSGLARDRHGHPGPG
MSMEG_5589|M.smegmatis_MC2_155 AAVADGLIPRFDGAESILLATAMLGATVMPHAVYLHSGLARDRHGHAE-G
MAB_1031c|M.abscessus_ATCC_199 PEAAAGLIPHFQGTESLLLATAMLGATVMPHAVYLHSGLTRDRHGRPAEG
** *:* *:**:***:*::**********:****. ****:. *
Mb0948c|M.bovis_AF2122/97 PQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTASIEGAYH
Rv0924c|M.tuberculosis_H37Rv PQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTASIEGAYH
MMAR_4584|M.marinum_M PYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAALNLQGREDTASIEGAYA
MUL_4445|M.ulcerans_Agy99 PYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAALNLQGREDTASIEGAYA
MAV_1044|M.avium_104 PHRRLLLRVTRWDVVLAMAVAGTVNAAMLLIAATNLQHRDVSASIEGAYA
MLBr_02098|M.leprae_Br4923 RSRRRLLRVTRLDVILAMTIAGIVNTAMLLVAAINLQHHQVTAYIEGTYT
Mflv_1822|M.gilvum_PYR-GCK EPRRALLRITRWDVGIAMLVAGAVNLSMLLVAATNLQGMADTDSIEGAHA
MSMEG_5589|M.smegmatis_MC2_155 PRLRMLLRVTRFDVGLAMLVAGAVNMAMLLVAATNLQGRGDTDSIEGAHA
MAB_1031c|M.abscessus_ATCC_199 EPRRRLLRITRWDVCLAMVFAGAVNMAMLLAAATNLRGRDGVDTIEGAHA
* ***:** ** :** .** ** :*** ** *:: ***::
Mb0948c|M.bovis_AF2122/97 AVHDTLGATIAVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWSVPMLVR
Rv0924c|M.tuberculosis_H37Rv AVHDTLGATIAVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWSVPMLVR
MMAR_4584|M.marinum_M AVHDTLGATIAVLFAIGLLASGLASTSVGAYAGAMIMQGLLHWSVPMAVR
MUL_4445|M.ulcerans_Agy99 AVHDTLGATIAVLFAIGLLASGLASTSVGAYAGAMIMQGLLHWSVPMAVR
MAV_1044|M.avium_104 AIHNTLGATIAVMFAVGLLASGLASSSVGAYAGAMIMQGLLHRSIPMVVR
MLBr_02098|M.leprae_Br4923 AIQDTLGATIAMLFAIGLLASSLASASVGAYAGALIMQGLLQRSIPMLIR
Mflv_1822|M.gilvum_PYR-GCK AVQNTLGDTVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSVPLLAR
MSMEG_5589|M.smegmatis_MC2_155 AVSDALGPTVALLFAIGLLASGLASTSVGAYAGAMIMQGLLKKSYPLLLR
MAB_1031c|M.abscessus_ATCC_199 AVRDSLGPTVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSIPIVAR
*: ::** *:*::**:*****.***:********:******: * *: *
Mb0948c|M.bovis_AF2122/97 RLITLGPALAILTLGFDPTRTLVLSQVVLSFGIPFAVLPLVKLTGSPAVM
Rv0924c|M.tuberculosis_H37Rv RLITLGPALAILTLGFDPTRTLVLSQVVLSFGIPFAVLPLVKLTGSPAVM
MMAR_4584|M.marinum_M RLVTLCPAVAILALGLDPTRTLVLSQVVLSFGIPFAVLPLVRLTSNPEVM
MUL_4445|M.ulcerans_Agy99 RLVTLCPAVAILALGLDPTRTLVLSQVVLSFGIPFAVLPLVRLTSNPEVM
MAV_1044|M.avium_104 RLITLCPALLILAVGYDTTRALVLSQVVLSFGIPFAVLPLIKLTSDRELM
MLBr_02098|M.leprae_Br4923 RLITLCPAIAILALGFDPTRALVLSQIVLSFGIPFAVLPLVKLTNNRGLM
Mflv_1822|M.gilvum_PYR-GCK RLITLLPALVILAVGIHPSRALVLSQVVLSFGIPFALIPLVRLTADRALM
MSMEG_5589|M.smegmatis_MC2_155 RLVTLVPALLVLAIGVDPSRALVLSQVVLSFGIPFALIPLVRLTSDKALM
MAB_1031c|M.abscessus_ATCC_199 RLITLLPALAILAAGIDPTRALVISQVVLSFGIPFALIPLIRLTGDRRLM
**:** **: :*: * ..:*:**:**:*********::**::** . :*
Mb0948c|M.bovis_AF2122/97 GGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
Rv0924c|M.tuberculosis_H37Rv GGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
MMAR_4584|M.marinum_M GSDTNHRLTTWIGWGVAVLISVLNVALIYLTLTG
MUL_4445|M.ulcerans_Agy99 GSDTNHRLTTWIGWGVAVLISVLNVALIYLTLTG
MAV_1044|M.avium_104 GSDANHRITTILGWGVGILISLLNMVLIWLTVTG
MLBr_02098|M.leprae_Br4923 GNDTNHPATTVLGWAVAILVSLLNVVLIYLTVTS
Mflv_1822|M.gilvum_PYR-GCK GADVNHRVTTAAGWVVAGLISLLNVVLIYLTLWG
MSMEG_5589|M.smegmatis_MC2_155 GGDANHRVTTAFGWGVAGLISVLNVVLIYLTVNG
MAB_1031c|M.abscessus_ATCC_199 GSDANHRVTTLLGWIIAALISALNVVLIFLTLAN
* *.** ** ** :. ::* **: **:**: .