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TTNGADPLGRFSALTREWFTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRLADPAR EPSQGTQVLYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDTPPNQRRAMIANPPDV LITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLALSLERLDQLLDTPAQRIGLSATVRPP EEVARFLSGQAPTTIVCPPAAKTFDLSVQVPVPDMANLDNNSIWPDVEERIVDLVEAHNSSIVFANSRRL AERLTSRLNEIHAERSGIELPAGPNPEVGGGAPAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLK SGRLRAVVATSSLELGIDMGAVDLVIQVEAPPSVASGLQRVGRAGHQVGEISQGVLFPKHRTDLIGCAVT VQRMQTGDIETLRVPANPLDVLAQHTVAVAALEPVDADAWFDAVRRSAPFATLPRSAFEATLDLLSGKYP STEFAELRPRLVYDRDTGTLTARPGAQRLAVTSGGAIPDRGMFTVYLASETEKPSRVGELDEEMVYESRP GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDSVGRPAELGAAVGAFTGELASLDRKAFDKRC QKMGFAGYATDNLHQLLREQREATGVVPSDTTFVVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLR ERYGIDEKPTASDDGIIVRLPDSGDTPPGADLFVFDADEIEPIVTAEVGGSALFASRFRECAARALLLPR RHPGKRSPLWHQRQRAAQLLDIARKYPDFPIVLEAVRECLQDVYDVPALIELMHKIAQRRLRIVEVETAT PSPFAASLLFGYVGAFMYEGDSPLAERRAAALALDTVLLSELLGRVELRELLDPAVVASTSAQLQHLTPE RAARDAEGVADLLRLLGPLTEADIAQRCTADNIGAWLDGLHAAKRALPVTYAGQTWWAAVEDIGLLRDGI GVPVPVGVPAAFTESASDPLGDLIGRYARTRGPFTTEQTAARFGLGVRVASDVLSRMAVDGRLIRGEFAA DLSGEQWCDAQVLKILRRRSLAALRAQVEPVSTDAYARFLPSWQHVGSTNTTGIDGLATVIEQLAGVPIP ASAVESLVFPQRVRDYQPAMLDELLASGEVMWSGAGQIGNGDGWVAFHLADTAPLTLTHGAEIEFTDTHR VILETLGHGGAYFFRQLTDGTVEGTAGQELKQALWELIWAGWVTGDTFAPVRAVLSGPRRSGAPAHRQRQ RPPRLSRYSVAHAQTRGTDPTVSGRWSALPAAEPDSTVRAHFQAELLLGRHGVLTKGAVGAEGVPGGFAT LYKVLSTFEDAGRCQRGYFVESLGGAQFAVASTVDRLRSYLDNVDPERPEYHAVVLAATDPANPYGAALG WPTDSEAHRPGRKAGALVALVDGRLVWFLERGGRSLLSFGADADAQRAAAGALTDLVSAGRIPSLLVERI NGVAVLDPDVDAERAVVQDALLGAGLSRTPRGLRLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1757 | - | - | 100% (1507) | DEAD/DEAH box helicase |
| M. smegmatis MC2 155 | MSMEG_6160 | - | 2e-20 | 29.08% (392) | ATP-dependent rna helicase, dead/deah box family protein |
| M. smegmatis MC2 155 | MSMEG_1540 | - | 2e-09 | 26.37% (402) | ATP-dependent RNA helicase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3324 | lhr | 0.0 | 77.41% (1514) | ATP-dependent helicase |
| M. gilvum PYR-GCK | Mflv_4810 | - | 0.0 | 76.77% (1524) | DEAD/DEAH box helicase domain-containing protein |
| M. tuberculosis H37Rv | Rv3296 | lhr | 0.0 | 77.48% (1514) | ATP-dependent helicase |
| M. leprae Br4923 | MLBr_01333 | helY | 1e-06 | 28.03% (264) | putative helicase, Ski2 subfamily |
| M. abscessus ATCC 19977 | MAB_3651 | - | 0.0 | 69.18% (1528) | ATP-dependent helicase Lhr |
| M. marinum M | MMAR_1238 | lhr | 0.0 | 76.04% (1536) | ATP-dependent helicase Lhr |
| M. avium 104 | MAV_4267 | - | 0.0 | 75.96% (1539) | DEAD/DEAH box helicase |
| M. thermoresistible (build 8) | TH_1222 | - | 0.0 | 78.23% (891) | PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED |
| M. ulcerans Agy99 | MUL_2324 | helY | 3e-06 | 32.79% (183) | ATP-dependent DNA helicase HelY |
| M. vanbaalenii PYR-1 | Mvan_1632 | - | 0.0 | 77.67% (1518) | DEAD/DEAH box helicase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4810|M.gilvum_PYR-GCK ---MPAKT-----DPLSRFSTLTREWFAGTFVEPTPAQAQAWNAISAGEN
Mvan_1632|M.vanbaalenii_PYR-1 MEHMPTET-----DPLARFSALTREWFTGTFVKPTPAQAQAWNAIADGDN
MSMEG_1757|M.smegmatis_MC2_155 --MTTNGA-----DPLGRFSALTREWFTTAFAAPTPAQADAWSAISEGNN
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 --MRFAQP-----SALSRFSALTRDWFTSTFAAPTAAQASAWAAIADGDN
Rv3296|M.tuberculosis_H37Rv --MRFAQP-----SALSRFSALTRDWFTSTFAAPTAAQASAWAAIADGDN
MMAR_1238|M.marinum_M --MSTARPEPLGPEPLGRFSAITREWFTNTFAAPTPAQASAWAAIAAGDN
MAV_4267|M.avium_104 -MSTRAEPRP--SDPLGRFSAITREWFTSTFAAPTTAQAQAWSAIADGHN
MAB_3651|M.abscessus_ATCC_1997 ---MSSEP-----GPLARFSAPTREWFTESFPTPTRAQSGAWQSIANGDN
MLBr_01333|M.leprae_Br4923 ---------------MTDLAELARFTAELPFSLDDFQQR-ACAALERGHG
MUL_2324|M.ulcerans_Agy99 ---------------MTELVELARFTADLPFALDDFQRR-ACAALEGGHG
Mflv_4810|M.gilvum_PYR-GCK TLVIAPTGSGKTLAAFLWAIDGLAR--------EPRAERGTRVLYVSPLK
Mvan_1632|M.vanbaalenii_PYR-1 TLVIAPTGSGKTLAAFLWAIDGLAR--------EPAAQRGTRVLYVSPLK
MSMEG_1757|M.smegmatis_MC2_155 TLVIAPTGSGKTLAAFLWAIDRLADP-------AREPSQGTQVLYVSPLK
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 TLVIAPTGSGKTLAAFLWALDSLAGSE-----PMSERPAATRVLYVSPLK
Rv3296|M.tuberculosis_H37Rv TLVIAPTGSGKTLAAFLWALDSLAGSE-----PMSERPAATRVLYVSPLK
MMAR_1238|M.marinum_M TLVIAPTGSGKTLAAFLWALDSLAR--------CPDRTAGTRVLYVSPLK
MAV_4267|M.avium_104 TLVIAPTGSGKTLAAFLWALDSLAG--------QAERAPGTRVLYVSPLK
MAB_3651|M.abscessus_ATCC_1997 TLVIAPTGSGKTLAAFLWAIDTLVQEKEAEAAAESRRLRGSRVLYVSPLK
MLBr_01333|M.leprae_Br4923 VLVCAPTGAGKTVVGEFAVHLALAA--------------GGKCFYTTPLK
MUL_2324|M.ulcerans_Agy99 VLVCAPTGAGKTVVGEFAVHLALAS--------------GGKCFYTTPLK
Mflv_4810|M.gilvum_PYR-GCK ALAVDVERNLRTPLTGISRIAERNGEEPPAISVGVRSGDTTPSKRRELIT
Mvan_1632|M.vanbaalenii_PYR-1 ALAVDVERNLRTPLTGISRIAERTGQQPPAISVGVRSGDTTPSKRRELIT
MSMEG_1757|M.smegmatis_MC2_155 ALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDTPPNQRRAMIA
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 ALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVGVRSGDTPPALRRQLVS
Rv3296|M.tuberculosis_H37Rv ALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVGVRSGDTPPALRRQLVS
MMAR_1238|M.marinum_M ALAVDVERNLRTPLAGLTRLAERRGLPPPQISVGVRSGDTPPAVRRQLIT
MAV_4267|M.avium_104 ALAVDVERNLRTPLAGLTRIAERAGLPAPDISVGVRSGDTPPAVRRQLIN
MAB_3651|M.abscessus_ATCC_1997 ALAVDVERNLRAPLAGIARTAARMGLPEPAITIGVRSGDTPAQRRRTLIS
MLBr_01333|M.leprae_Br4923 ALSNQKYTDLTARYG--------------RNRIGLLTGDQSVNGDSPVVV
MUL_2324|M.ulcerans_Agy99 ALSNQKHTDLTARYG--------------RDKTGLLTGDLAVNANAPVVV
Mflv_4810|M.gilvum_PYR-GCK KPPDILITTPESLFLMLTSAARESLSDIETVIVDEVHAVAATKRGAHLAV
Mvan_1632|M.vanbaalenii_PYR-1 KPPDILITTPESLFLMLTSAARETLSQVQTVIVDEVHAVAGTKRGAHLAV
MSMEG_1757|M.smegmatis_MC2_155 NPPDVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLAL
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 QPPDVLITTPESLFLMLTSAARQTLTGVQTVIIDEIHAIAATKRGAHLAL
Rv3296|M.tuberculosis_H37Rv QPPDVLITTPESLFLMLTSAARQTLTGVQTVIIDEIHAIAATKRGAHLAL
MMAR_1238|M.marinum_M RPPDVLITTPESLFLMLTSAARETLAGVQTVIVDEIHAIAATKRGAHLAL
MAV_4267|M.avium_104 RPPDVLITTPESLFLMLTSAARETLAGVQTVIVDEIHAIAGGKRGAHLAL
MAB_3651|M.abscessus_ATCC_1997 SPPDILITTPESLYLMLTSAARETLDTVRTVIVDEVHAVAGTKRGAHLAL
MLBr_01333|M.leprae_Br4923 MTTEVLRN--------MLYADSFALQGLSHVVMDEVHFIADRMRGPVWEE
MUL_2324|M.ulcerans_Agy99 MTTEVLRN--------MLYADSPALPGLSYVVMDEVHFLADRMRGPVWEE
Mflv_4810|M.gilvum_PYR-GCK SLERLDAMLPKPAQ-----RIGLSATVRPPEEVARFLSGASP---TTIVA
Mvan_1632|M.vanbaalenii_PYR-1 SLERLDAMLPKPAQ-----RIGLSATVRPPEEVARFLSGAAP---TTIVA
MSMEG_1757|M.smegmatis_MC2_155 SLERLDQLLDTPAQ-----RIGLSATVRPPEEVARFLSGQAP---TTIVC
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 SLERLDDLSSRRRA----QRIGLSATVRPPEELARFLSGQSP---TTIVA
Rv3296|M.tuberculosis_H37Rv SLERLDDLSSRRRA----QRIGLSATVRPPEELARFLSGQSP---TTIVA
MMAR_1238|M.marinum_M SLERLDQLAPDRRAGPPAQRIGLSATVRPPEELARFLSGSAP---TTIVA
MAV_4267|M.avium_104 SLERLDALREGRPA----QRIGLSATVRPPDELARFLSGAAPGTRTTVVA
MAB_3651|M.abscessus_ATCC_1997 SLERLDERLSQPAQ-----RIGLSATVKPAAEVARFLSGRAP---ATVVA
MLBr_01333|M.leprae_Br4923 VILHLPDDVR---------MVSLSATVSNAEEFGGWVQTVRG--------
MUL_2324|M.ulcerans_Agy99 VILHLPDEVR---------VVSLSATVSNAEEFGGWIQTVRG--------
Mflv_4810|M.gilvum_PYR-GCK PPAAKTFDLTVQVPVPDMAAPN---------------TGSIWPDVEERIV
Mvan_1632|M.vanbaalenii_PYR-1 PPAAKTFDLTVQVPVPDMANLE---------------NNSIWPEVEQRIV
MSMEG_1757|M.smegmatis_MC2_155 PPAAKTFDLSVQVPVPDMANLD---------------NNSIWPDVEERIV
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 PPAAKTVELSVQVPVPDMANLT---------------DNTIWPDVEARLV
Rv3296|M.tuberculosis_H37Rv PPAAKTVELSVQVPVPDMANLT---------------DNTIWPDVEARLV
MMAR_1238|M.marinum_M PHSAKTFDLTVQVPVADMANLA---------------NNTIWPDVESRLV
MAV_4267|M.avium_104 PPSAKTVELSVQVPVPDMANLA---------------NNTIWPDVENRLV
MAB_3651|M.abscessus_ATCC_1997 PASPKTFDLSVVVPVSDMSAPESFPEPEASPDSTRGGATSLWPHVEQRIV
MLBr_01333|M.leprae_Br4923 -DTTVVVDEHRPVPLWQHVLVG------------------------KRLF
MUL_2324|M.ulcerans_Agy99 -DTAVVVDEHRPVPLWQHVLVG------------------------KRLF
Mflv_4810|M.gilvum_PYR-GCK DLIEAHNSSIVFTNSRRLAERLTARINEIHAERTGIELG-AHNPGVAGGA
Mvan_1632|M.vanbaalenii_PYR-1 DLVEAHNSSIVFANSRRLAERLTARLNEIHAERLGVELG-GANPGVAGGA
MSMEG_1757|M.smegmatis_MC2_155 DLVEAHNSSIVFANSRRLAERLTSRLNEIHAERSGIELPAGPNPEVGGGA
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 DLIESHNSTIVFANSRRLAERLTARLNEIHAARCGIELAPDTNQQVAGGA
Rv3296|M.tuberculosis_H37Rv DLIESHNSTIVFANSRRLAERLTARLNEIHAARCGIELAPDTNQQVAGGA
MMAR_1238|M.marinum_M DLIESHNSTIVFANSRRLAERLTARLNEIHAERSGMTLPSEANTQVAGGA
MAV_4267|M.avium_104 DLIEAHGSTIVFANSRRLAERLTARLNEIHAERSGVELSATANPKVAGGA
MAB_3651|M.abscessus_ATCC_1997 DLIEAHRSSIVFANSRRLAERLTARFNEIHAERLGLDLTPMPNPDVPGGP
MLBr_01333|M.leprae_Br4923 DLFDYDSN-----VDQSPVN------------------------------
MUL_2324|M.ulcerans_Agy99 DLFDYQADKPAGSSRQARVN------------------------------
Mflv_4810|M.gilvum_PYR-GCK PAHLMGSGQTYGAEPVLARAHHGSVSKEARADVEDALKSGRLKAVVATSS
Mvan_1632|M.vanbaalenii_PYR-1 PAHLMGSGQTYGAEPLLARAHHGSVSKEARADVEEALKSGRLKAVVATSS
MSMEG_1757|M.smegmatis_MC2_155 PAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLRAVVATSS
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 PAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKRGQLKAVVATSS
Rv3296|M.tuberculosis_H37Rv PAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKRGQLKAVVATSS
MMAR_1238|M.marinum_M PAQIMASGQTFGAATLLARAHHGSVSKEQRAQVEEDLKRGALKAVVATSS
MAV_4267|M.avium_104 PAHIMASGQTYGVEPILARAHHGSVSKEQRALVEEDLKRGLLKAVVATSS
MAB_3651|M.abscessus_ATCC_1997 PAHIMGSGQTYGAAPLLARAHHGSVSKEQRADIEDDLKTGRLKCVVATSS
MLBr_01333|M.leprae_Br4923 --------------PNLLRHIAHCREADRMSDWRNPRR------------
MUL_2324|M.ulcerans_Agy99 --------------PDLLRHIAHRREADRMSDWE-PRRSG----------
Mflv_4810|M.gilvum_PYR-GCK LELGIDMGAVDLVIQVETPPSVASGLQRVGRAGHQVGEISQGVLFPKHRT
Mvan_1632|M.vanbaalenii_PYR-1 LELGIDMGAVDLVIQVETPPSVASGLQRIGRAGHQVGEISQGVLFPKHRT
MSMEG_1757|M.smegmatis_MC2_155 LELGIDMGAVDLVIQVEAPPSVASGLQRVGRAGHQVGEISQGVLFPKHRT
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 LELGIDMGAVDLVIQVQAPPSVASGLQRIGRAGHQVGEISRGVLFPKHRT
Rv3296|M.tuberculosis_H37Rv LELGIDMGAVDLVIQVQAPPSVASGLQRIGRAGHQVGEISRGVLFPKHRT
MMAR_1238|M.marinum_M LELGIDMGAVDLVIQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHRT
MAV_4267|M.avium_104 LELGIDMGAVDLVIQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHRT
MAB_3651|M.abscessus_ATCC_1997 LELGIDMGAVDLVVQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHRT
MLBr_01333|M.leprae_Br4923 -RAGRGSGVRPRFYRSLARPEVIAILDAEG--------LLPAITFVFSR-
MUL_2324|M.ulcerans_Agy99 -RGEYGRGRRPRFYRPPPRPDVIATLDSAG--------LLPAITFVFSR-
Mflv_4810|M.gilvum_PYR-GCK DLIGCAVSVQRMLAGQIETMRVPANPLDVLAQHTVAASALEPINADAWFD
Mvan_1632|M.vanbaalenii_PYR-1 DLIGCAVSVQRMLAGQIETMRVPANPLDVLAQHTVAACALEPINAEAWFD
MSMEG_1757|M.smegmatis_MC2_155 DLIGCAVTVQRMQTGDIETLRVPANPLDVLAQHTVAVAALEPVDADAWFD
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 DLLGCAVSVQRMLAGEIETMRVPANPLDILAQHTVAAAALEPLDADAWFD
Rv3296|M.tuberculosis_H37Rv DLLGCAVSVQRMLAGEIETMRVPANPLDILAQHTVAAAALEPLDADAWFD
MMAR_1238|M.marinum_M DLLGCAISVQRMRTGQIETMRVPANPLDILAQHTVAAAALEPLDADQWFD
MAV_4267|M.avium_104 DLIGCAVTVQRMLAGQIETMRVPANPLDILAQQTVAAAALEPLDADRWFD
MAB_3651|M.abscessus_ATCC_1997 DLLGCAVTVRRMLDGDIETLQVPANPLDILAQHTVAACALESMDVEKWFD
MLBr_01333|M.leprae_Br4923 --FGCDAAVQQCLR----------SPLRLTSEEE----------------
MUL_2324|M.ulcerans_Agy99 --AGCDAAVQQCLR----------SPLRLTSEEE----------------
Mflv_4810|M.gilvum_PYR-GCK TVRRSAPFATLPRSAFEATLDLLSGKYPSTEFAELRPRIVYDRDNGMLTS
Mvan_1632|M.vanbaalenii_PYR-1 TVRRSAPFATLPRSAFEATLDLLSGKYPSTEFAELRPRIVYDRDTGTLTS
MSMEG_1757|M.smegmatis_MC2_155 AVRRSAPFATLPRSAFEATLDLLSGKYPSTEFAELRPRLVYDRDTGTLTA
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 TVRRAAPFATLPRSLFEATLDLLSGKYPSTEFAELRPRLVYDRDTGTLTA
Rv3296|M.tuberculosis_H37Rv TVRRAAPFATLPRSLFEATLDLLSGKYPSTEFAELRPRLVYDRDTGTLTA
MMAR_1238|M.marinum_M TVRRSASFATLPRSVFEATLDLLSGKYPSTEFAELRPRLVYDRGTGTLTA
MAV_4267|M.avium_104 TVRRAAPFATLPRSIYEATLDLLSGKYPSTEFAELRPRLVYDRNTGTLTA
MAB_3651|M.abscessus_ATCC_1997 VVRRSAPFTSLPRSAFDAVLDLLSGKYPSTDFAELRPRVVYDRDEGTLTG
MLBr_01333|M.leprae_Br4923 ------------RAQIAEVIDHRCGDLADADLAVLG---YYEWREGLLRG
MUL_2324|M.ulcerans_Agy99 ------------RAQIAEVIDHRCGDLEDDDLAVLG---YYEWREGLLRG
Mflv_4810|M.gilvum_PYR-GCK RPGAQRLAVTSGGAIPDRGMFTVFLASSAESEKPSRVGELDEEMVYESRP
Mvan_1632|M.vanbaalenii_PYR-1 RPGAQRLAVTSGGAIPDRGLFTVFLASSADSEKPSRVGELDEEMVYESRP
MSMEG_1757|M.smegmatis_MC2_155 RPGAQRLAVTSGGAIPDRGMFTVYLASETE--KPSRVGELDEEMVYESRP
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 RPGAQRLAVTSGGAIPDRGLFAVYLATER----PSRVGELDEEMVYESRP
Rv3296|M.tuberculosis_H37Rv RPGAQRLAVTSGGAIPDRGLFAVYLATER----PSRVGELDEEMVYESRP
MMAR_1238|M.marinum_M RPGAQRLAVTSGGAIPDRGLFTVYLASEAE--KPSRVGELDEEMVYESRP
MAV_4267|M.avium_104 RPGAQRLAVTSGGAIPDRGLFTVYLASEAE--KPSRVGELEEEMVYESRP
MAB_3651|M.abscessus_ATCC_1997 RPGAQRLAVTSGGAIPDRGLFTVYMYAGAEGEKPSRVGELDEEMVYESRP
MLBr_01333|M.leprae_Br4923 ------LAAHHAGMLP----------------------------------
MUL_2324|M.ulcerans_Agy99 ------LAAHHAGMLP----------------------------------
Mflv_4810|M.gilvum_PYR-GCK GDVISLGATSWRITEITHDRVLVIPAPGEPARLPFWRGDGVGRPVELGAA
Mvan_1632|M.vanbaalenii_PYR-1 GDVISLGATSWRITEITHDRVLVIPAPGEPARLPFWRGDGVGRPAELGAA
MSMEG_1757|M.smegmatis_MC2_155 GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDSVGRPAELGAA
TH_1222|M.thermoresistible__bu --------------------------------------------------
Mb3324|M.bovis_AF2122/97 GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDDAGRPAELGAA
Rv3296|M.tuberculosis_H37Rv GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDDAGRPAELGAA
MMAR_1238|M.marinum_M GDVISLGATSWRITEITHDRVLVIPAPGEPARLPFWRGDDVGRPAELGAA
MAV_4267|M.avium_104 GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDGVGRPAELGAA
MAB_3651|M.abscessus_ATCC_1997 GDVISLGATSWRITEITHERVVVVPAFGQPGRLPFWRGDSVGRPAELGIA
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK IGAFNGELARLDRPAFESRCRDVGFDDFATDNLWQLISEQREATSSVPSD
Mvan_1632|M.vanbaalenii_PYR-1 IGAFTGELARLDRDAFESRCQEVGFDAFATDNLWQLISEQRDATSAVPSD
MSMEG_1757|M.smegmatis_MC2_155 VGAFTGELASLDRKAFDKRCQKMGFAGYATDNLHQLLREQREATGVVPSD
TH_1222|M.thermoresistible__bu ----------------------MGFDEFATTNLWQLLDEQRQSTGVVPSD
Mb3324|M.bovis_AF2122/97 LGALTGELAALDRTAFGTRCAGLGFDDYATDNLWRLLDDQRTATAVVPTD
Rv3296|M.tuberculosis_H37Rv LGALTGELAALDRTAFGTRCAGLGFDDYATDNLWRLLDDQRTATAVVPTD
MMAR_1238|M.marinum_M LGALTGELARLDRAEFDKRCAGLGFDDFATDNLWGLLDDQKTATRVVPTD
MAV_4267|M.avium_104 LGAFTGELAGLSREEFDSRCAALGFDAYAVDNLYGLFDEQRTAAGVVPTD
MAB_3651|M.abscessus_ATCC_1997 LGQLTGELASARDAEFDKRCAAMGFDDFATGNLRTLLTDQLRSTGAVPTD
MLBr_01333|M.leprae_Br4923 ------------------AFRHAVEELFTAGLVKAVFATETLALGINMPA
MUL_2324|M.ulcerans_Agy99 ------------------AFRHTVEELFTAGLVKAVFATETLALGINMPA
::. : :: : : .
Mflv_4810|M.gilvum_PYR-GCK TTLVVERFRDELGDWRVILHSPYGLRVHGPLALAVGKRLYERFGIDEKPT
Mvan_1632|M.vanbaalenii_PYR-1 TTLVVERFRDELGDWRVILHSPYGLRVHGPLALAVGKRLYERYGIDEKPT
MSMEG_1757|M.smegmatis_MC2_155 TTFVVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRERYGIDEKPT
TH_1222|M.thermoresistible__bu TTLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLAERYGIDEKPT
Mb3324|M.bovis_AF2122/97 STLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDEKPT
Rv3296|M.tuberculosis_H37Rv STLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDEKPT
MMAR_1238|M.marinum_M TTLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGLDEKPT
MAV_4267|M.avium_104 TTLLVERFRDELGDWRVILHSPYGLGVNGPLALAVGRRLRERYGIDEKPT
MAB_3651|M.abscessus_ATCC_1997 TTLIVERFRDELGDWRIVLHCPYGLRVNGPLALAISDRLQQRYGVSESPT
MLBr_01333|M.leprae_Br4923 RTVVLERLVKFNGKQ------------HVPLTPGEYTQLTGRAGRRGIDV
MUL_2324|M.ulcerans_Agy99 RTVVLERLVKFNGEQ------------HVPLTPGEYTQLTGRAGRRGIDV
*.::**: . *. : **: . :* * * .
Mflv_4810|M.gilvum_PYR-GCK ASDDGIIVRLPDTDD--------TAPGADIFVFDADEIEPLVTTEVSSSA
Mvan_1632|M.vanbaalenii_PYR-1 ASDDGIIVRLPDTDD--------TAPGADIFVFDADEIEPLVTAEVSSSA
MSMEG_1757|M.smegmatis_MC2_155 ASDDGIIVRLPDSGD--------TPPGADLFVFDADEIEPIVTAEVGGSA
TH_1222|M.thermoresistible__bu ASDDGIIVRLPDTGD--------TQPGAELFVFDADEIEPLVTAEVGGSA
Mb3324|M.bovis_AF2122/97 ASDNGIMVRLPDTVS----AGEDSPPGAELFVFDADEIDPIVTTEVAGSA
Rv3296|M.tuberculosis_H37Rv ASDNGIVVRLPDTVS----AGEDSPPGAELFVFDADEIDPIVTTEVAGSA
MMAR_1238|M.marinum_M ASDDGIVVRLPDTISD---TGTETPPGAELFLFDADEIDAIVTAEVGASA
MAV_4267|M.avium_104 ASDDGVVVRLPDTVSDFASDGGDTPPGAELFVFDADEIDPIVTAEVGGSA
MAB_3651|M.abscessus_ATCC_1997 ATDDGIVVRLPDTDD--------SPPGADLFVFDAAEIESIVTREVGGSA
MLBr_01333|M.leprae_Br4923 EGHAVVIWHPSEDTS-----------------------GPSAVAGLASAR
MUL_2324|M.ulcerans_Agy99 EGHAVVLWHPTDENA-----------------------DPSAVAGLASTR
. :: : .: . .. :..:
Mflv_4810|M.gilvum_PYR-GCK LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVARNYPDFPIV
Mvan_1632|M.vanbaalenii_PYR-1 LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVAKGYPDFPIV
MSMEG_1757|M.smegmatis_MC2_155 LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDIARKYPDFPIV
TH_1222|M.thermoresistible__bu LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVARKYPDFPIV
Mb3324|M.bovis_AF2122/97 LFASRFRESAARALLLPRRHPGRRSPLWQQRQRAARLLEVARKYPDFPIV
Rv3296|M.tuberculosis_H37Rv LFASRFRESAARALLLPRRHPGRRSPLWQQRQRAARLLEVARKYPDFPIV
MMAR_1238|M.marinum_M LFASRFRESAARALLLPRRHPGRRSPLWHQRQRAAQLLDVARKYPDFPMV
MAV_4267|M.avium_104 LFASRFRECAARALLLPRRHPGRRSPLWQQRQRAAQLLEVARKYPDFPVV
MAB_3651|M.abscessus_ATCC_1997 LFAARFRECAARALLLPRRTPGRRSPLWQQRQRAAQLLDVARKHSDFPMV
MLBr_01333|M.leprae_Br4923 TFP-------LRSSFVPSYNMTINLVHWMSPERAHALLEQS---------
MUL_2324|M.ulcerans_Agy99 TFP-------LRSSFAPSYNMTINLVQHMGPEQAHRLLEQS---------
*. *: : * . ::* **: :
Mflv_4810|M.gilvum_PYR-GCK LEAVRECLQDVYDVPALTALMDRIAQRRVRILEVETPTPSPFAASLLFGY
Mvan_1632|M.vanbaalenii_PYR-1 LEAVRECLQDVYDVPTLTALMGRIAQRRVRLLEVETPTPSPFAASLLFGY
MSMEG_1757|M.smegmatis_MC2_155 LEAVRECLQDVYDVPALIELMHKIAQRRLRIVEVETATPSPFAASLLFGY
TH_1222|M.thermoresistible__bu LETVRECLQDVYDVPTLTELMRGIAQRRLRLIEVETAAPSPFAASLLFGY
Mb3324|M.bovis_AF2122/97 LETVRECLQNVYDVPILVELMARIAQRRVRVAEAETAKPSPFAASLLFGY
Rv3296|M.tuberculosis_H37Rv LETVRECLQDVYDVPILVELMARIAQRRVRVAEAETAKPSPFAASLLFGY
MMAR_1238|M.marinum_M LETVRECLQDVYDVPTLTTLMTDIAQRRVRVAETETTKPSPFAASLLFGY
MAV_4267|M.avium_104 LETVRECLQDVYDVPALVALMAGIAQRRVRVLEVETQRPSPFAASLLFGY
MAB_3651|M.abscessus_ATCC_1997 LEALRECLQDVYDISTLVRLMSGIEQRRIRIVEVQTDTPSPFAAAQLFSY
MLBr_01333|M.leprae_Br4923 -------FAQYQADRSVVGLVRGIERCTQVLGDISSELGGPDAPILEYAR
MUL_2324|M.ulcerans_Agy99 -------FAQYQADRSVVGLVRGIERGREMLDELAAELGGPDAPILDYAR
: : : *: * : : : : .* *. :.
Mflv_4810|M.gilvum_PYR-GCK VGAFMYEGDSPLAERRAAALALDPTLLAELLGRVELRELLDPDVIATTTR
Mvan_1632|M.vanbaalenii_PYR-1 VGAFMYEGDSPLAERRAAALSLDPTLLAELLGRVELRELLDADVVTTTAR
MSMEG_1757|M.smegmatis_MC2_155 VGAFMYEGDSPLAERRAAALALDTVLLSELLGRVELRELLDPAVVASTSA
TH_1222|M.thermoresistible__bu VGAFIYEGDSPLAERRAAALSLDPTLLAELLGRVELRELLDPDVVATTGR
Mb3324|M.bovis_AF2122/97 VGAFMYEGDTPLAERRAAALALDGTLLAELLGRVELRELLDPDVIAATSR
Rv3296|M.tuberculosis_H37Rv VGAFMYEGDTPLAERRAAALALDGTLLAELLGRVELRELLDPDVIAATSR
MMAR_1238|M.marinum_M VGAFMYEGDVPLAERRAAALSLDSTLLAELLGRVELRELLDPEVIAATGR
MAV_4267|M.avium_104 VGAFMYEGDSPLAERRAAALSLDSTLLAELLGRVELRELLDPEVVAATAR
MAB_3651|M.abscessus_ATCC_1997 IGGFMYDEDRPLAERRAAALSLDTNLLAELMGRVELRELLDPAVIDATER
MLBr_01333|M.leprae_Br4923 LRARIAEMER----------------AQSFVFRLQRKQAANDVLAALRRG
MUL_2324|M.ulcerans_Agy99 MRARVTEMER----------------SQARASRLQRRQEASEALAALRKG
: . : : : *:: :: . :
Mflv_4810|M.gilvum_PYR-GCK QLQHLTPERAARDAEGVADLLRLLGPLTVDEIAER---CVQPDIGGWLEG
Mvan_1632|M.vanbaalenii_PYR-1 QLQHLTPERLARDAEGVADLLRLLGPLTTEEIAAR---CVVSEVGGWLEG
MSMEG_1757|M.smegmatis_MC2_155 QLQHLTPERAARDAEGVADLLRLLGPLTEADIAQR---CTADNIGAWLDG
TH_1222|M.thermoresistible__bu QLQHLTADRAVRDVEGVADLLRMLGPLTAEEIAAR---STSADVGGWLDE
Mb3324|M.bovis_AF2122/97 QLQHLAADRVARDAEGVADLLRLLGPLTEDEIAAR---AGAPEVSGWLDG
Rv3296|M.tuberculosis_H37Rv QLQHLAADRVARDAEGVADLLRLLGPLTEDEIAAR---AGAPEVSGWLDG
MMAR_1238|M.marinum_M QLQHLCADRAARDAEGVADLLRLLGPLTEDEVAARSDTTGGTDIGGWLEG
MAV_4267|M.avium_104 ALQHLAPERAARDAEAVADLLRLLGPLTEDEVVARAGGADAVEVRGWLEG
MAB_3651|M.abscessus_ATCC_1997 QLQHLAEERKARDAEALADLFRLLGPLTAEEIAQR----CAGPGAAWLDE
MLBr_01333|M.leprae_Br4923 DIITITHGR-------------------------------HGGLAVVLES
MUL_2324|M.ulcerans_Agy99 DIITITHGR-------------------------------RGGLAVVLES
: : * *:
Mflv_4810|M.gilvum_PYR-GCK LLTSKRVVTLSFAGQTWWAAIEDIGRLRDGVGVAVPVGVPIAFLEPIVDP
Mvan_1632|M.vanbaalenii_PYR-1 LLGAKRAVQVSFAGQSWWAAVEDIGRLRDGVGVAVPVGVPMAFLEQVVDP
MSMEG_1757|M.smegmatis_MC2_155 LHAAKRALPVTYAGQTWWAAVEDIGLLRDGIGVPVPVGVPAAFTESASDP
TH_1222|M.thermoresistible__bu LAAARRALRVSYAGRQWWVAVEDIGLLRDAVGVAVPVGVPTTFTGAVADP
Mb3324|M.bovis_AF2122/97 LRAAKRALVVSFAGRSWWVAVEDMGRLRDGVGAAVPVGLPASFTEAVADP
Rv3296|M.tuberculosis_H37Rv LRAAKRALVVSFAGRSWWVAVEDMGRLRDGVGAAVPVGLPASFTEAVADP
MMAR_1238|M.marinum_M LRAARRALEVSYAGRSWWVAVEDIGRLRDGVGAAVPVGLPAAFTEAVADP
MAV_4267|M.avium_104 LRAARRAVPVSFAGRSWWVAIEDIGRLRDGLGIAVPLGVPAAFTEEVADP
MAB_3651|M.abscessus_ATCC_1997 LVSARRVVGTSYGQRSWWAAVEDVARLRDALGVPVPPGVPAAFTDAATDP
MLBr_01333|M.leprae_Br4923 ARDSSNPRPLVLTEHRWAGRISSA----DYMGAAAPVGS--------MTL
MUL_2324|M.ulcerans_Agy99 ARDSSDPRPLVLTENRWAGRISSA----DYTGESPPVGS--------MTL
: . * :.. * * . * *
Mflv_4810|M.gilvum_PYR-GCK LSELLSRYARTRGPFTTMEAATRFGLGVRVAAD-----VLGRLTA----D
Mvan_1632|M.vanbaalenii_PYR-1 LGELLSRYARTRGPFTTAEAAARFGLGLRVAAD-----VLGRLAV----D
MSMEG_1757|M.smegmatis_MC2_155 LGDLIGRYARTRGPFTTEQTAARFGLGVRVASD-----VLSRMAV----D
TH_1222|M.thermoresistible__bu LGELLGRYARTRGPFTTAQAAARFGLGLRVAGD-----VLHRMAA----D
Mb3324|M.bovis_AF2122/97 LGELLGRYARTHTPFTTAAAAARFGLGLRVTAD-----VLGRLAS----D
Rv3296|M.tuberculosis_H37Rv LGELLGRYARTHTPFTTAAAAARFGLGLRVTAD-----VLGRLAS----D
MMAR_1238|M.marinum_M LAELLGRYARTHPPFTTAEAAGRFGLGLRVTAD-----VLGRLAS----D
MAV_4267|M.avium_104 LGELLGRYARTHTPFSTAEAAARFGLGLRVTAD-----VLGRLADPSTSQ
MAB_3651|M.abscessus_ATCC_1997 LAELLSRYARTHGPFTTGEAAQRFGLGVRVAAD-----TLSAMAA----R
MLBr_01333|M.leprae_Br4923 PKRVEHRQQRVRRDLASALRSAATRLSVPDIGDGVDGDKIG---------
MUL_2324|M.ulcerans_Agy99 PKRVEHRQPRVRRDLASALRSAAAGMTAPAARR----EKT----------
: * *.: ::: : :
Mflv_4810|M.gilvum_PYR-GCK GKLVRGEFTDLP-----TESGVEQWCDAEVLRILRRRSLAALRAQIEPVS
Mvan_1632|M.vanbaalenii_PYR-1 GKLVRGEFTDAP-----TDSG-GQWCDAEVLRILRRRSLAALRAQIEPVS
MSMEG_1757|M.smegmatis_MC2_155 GRLIRGEFAAD------LSG--EQWCDAQVLKILRRRSLAALRAQVEPVS
TH_1222|M.thermoresistible__bu GRLVRGEFTTD------AVDTTEQWCDAEVLRILRRRSLAALRAQVEPVS
Mb3324|M.bovis_AF2122/97 GRLVRGEFVAA----AEGSAGGEQWCDAEVLRILRRRSLAALRAQAEPVS
Rv3296|M.tuberculosis_H37Rv GRLVRGEFVAA----AKGSAGGEQWCDAEVLRILRRRSLAALRAQAEPVS
MMAR_1238|M.marinum_M GRLVRGDFVATG---VFGGAGSEQWCDAEVLRILRRRSLAALRAQVEPVS
MAV_4267|M.avium_104 GRLVRGDFVAARPSEPGGVLGAEQWCDADVLRILRRRSLAALRAQVEPVS
MAB_3651|M.abscessus_ATCC_1997 GQLVRGEFTSD-------ATDSEQWCDAEVLRILRRRSLAALRAQVEPVS
MLBr_01333|M.leprae_Br4923 ----------------------------FNDGVLHDPELASLRAQLR---
MUL_2324|M.ulcerans_Agy99 -------------------------------RAPHDPDLASLREKLR---
: .**:** : .
Mflv_4810|M.gilvum_PYR-GCK TGAFGRFLPAWQMVGADSAS------GVDGLASVIDQLAGVPVPASAVEP
Mvan_1632|M.vanbaalenii_PYR-1 TAAFGRFLPAWQMLGGDAVS------GVDGLAAVIDQLAGVPMPASAVEP
MSMEG_1757|M.smegmatis_MC2_155 TDAYARFLPSWQHVGSTNT------TGIDGLATVIEQLAGVPIPASAVES
TH_1222|M.thermoresistible__bu TAAFGRFLPAWQQVGTAN-------SGIDGLAAVIEQLAGVPMPASAVES
Mb3324|M.bovis_AF2122/97 TAAYGRFLPAWQHVSAGNS-------GIDGLAAVIDQLAGVRIPASAIEP
Rv3296|M.tuberculosis_H37Rv TAAYGRFLPAWQHVSAGNS-------GIDGLAAVIDQLAGVRIPASAIEP
MMAR_1238|M.marinum_M TAAYGRFLPEWHQVGGADSS----HGGIDRLASVIDQLAGVRIPASALEP
MAV_4267|M.avium_104 TAAYGRFLPAWHRVGAAESSRAPGHSGLDGLMSVIEQLAGVRLPASALEP
MAB_3651|M.abscessus_ATCC_1997 TSAFARFLPDWQYLDSNLR-------GIDGVATVIEQLAGVPIPASAWEP
MLBr_01333|M.leprae_Br4923 ----------------------------------RHRSNNAPGLDTQLQQ
MUL_2324|M.ulcerans_Agy99 ----------------------------------RHPCHNAPGVESRIRQ
. .. : .
Mflv_4810|M.gilvum_PYR-GCK LILGQRVRDYQPGMLDELLASGEVLWSGAGSLSA----ADGWVSFHPADT
Mvan_1632|M.vanbaalenii_PYR-1 LIFGQRVRDYQPGMLDELLASGEVLWSGVGSLST----ADGWVAFHLAET
MSMEG_1757|M.smegmatis_MC2_155 LVFPQRVRDYQPAMLDELLASGEVMWSGAGQIGN----GDGWVAFHLADT
TH_1222|M.thermoresistible__bu LILPQRVRDYQPAMLDELLASGEVIWSGAGAIGGGATGADGWIAFHLGDS
Mb3324|M.bovis_AF2122/97 LVLAPRIRDYSPAMLDELLASGDVTWSGAGSISG----SDGWIALHPADS
Rv3296|M.tuberculosis_H37Rv LVLAPRIRDYSPAMLDELLASGDVTWSGAGSISG----SDGWIALHPADS
MMAR_1238|M.marinum_M LVLAPRVRDYSPAMLDELLATGEVTWAGAGSISG----SDGWVTLHLADS
MAV_4267|M.avium_104 LVLAPRVRDYSPALLDELLATGEVTWSGAGSISG----SDGWIALHPSES
MAB_3651|M.abscessus_ATCC_1997 LILARRIRDYSPQMLDELLASGEAVWSGQGSISA----QDGWIALHPSGV
MLBr_01333|M.leprae_Br4923 AERYLRIERYNAQLQRKVAAATNSLARTFDRIVG------------LLIE
MUL_2324|M.ulcerans_Agy99 AEHYLRIERDNAQLENKVAAATNSLARTFDRIVG------------LLTE
*:. .. : :: *: : . :
Mflv_4810|M.gilvum_PYR-GCK APLSLAPPGDLDLTDVHHQILAALAGGGAYFFRQLSLD---GVSSESLKE
Mvan_1632|M.vanbaalenii_PYR-1 APLSLAPYGDLGLTDIHHAVLAALAGGGAYFFRQLTVD---GVGTESLKE
MSMEG_1757|M.smegmatis_MC2_155 APLTLTHGAEIEFTDTHRVILETLGHGGAYFFRQLTDGTVEGTAGQELKQ
TH_1222|M.thermoresistible__bu APLTLAEPAEIEFTDVHRAILDTLGGGGGYFFRQLAGG--AGTDTTAVRT
Mb3324|M.bovis_AF2122/97 APMTLAEPAEIDFTDAHRAILASLGTGGAYFFRQLTHD---GLTEAELKA
Rv3296|M.tuberculosis_H37Rv APMTLAEPAEIDFTDAHRAILASLGTGGAYFFRQLTHD---GLTEAELKA
MMAR_1238|M.marinum_M APLTLAAPAEIEFGEAHRAILDTLAGGGAYFFRQLIGD---IPDEAAIKA
MAV_4267|M.avium_104 APLTLQGPADIELGEAHRAILDVLAGGGGYFFRQLATD---GVSDAELKA
MAB_3651|M.abscessus_ATCC_1997 APATLAAAETVILDDAHRAILNCLTAGGGYFFRQFGSD--------ATRA
MLBr_01333|M.leprae_Br4923 RDFIRGPADDPQVTDDGRLLARIYSESDLLVAECLRTG------------
MUL_2324|M.ulcerans_Agy99 REYIHGPADDPRVTDDGRLLARIYSESDLLVAECLRTG------------
. : : : .. . . : .
Mflv_4810|M.gilvum_PYR-GCK ALWQLIWAGYVGGDTFAPVRALLAGTKGPGSRRTAAPSHR-HRRPPRLSR
Mvan_1632|M.vanbaalenii_PYR-1 ALWQLIWAGYVGGDTFAPVRALLAGARGSGPRKSATPSHR-HRRAPRLSR
MSMEG_1757|M.smegmatis_MC2_155 ALWELIWAGWVTGDTFAPVRAVLSGP-----RRSGAPAHRQRQRPPRLSR
TH_1222|M.thermoresistible__bu ALWELVWAGWVTGDTFAPVRAMLSGAGR-TGRRGGAPAHQQSRRPPRLSR
Mb3324|M.bovis_AF2122/97 ALWELIWAGRVTGDTFAPVRAVLGGAG---TRKRAAPAHG-GHRPPRLSR
Rv3296|M.tuberculosis_H37Rv ALWELIWAGRVTGDTFAPVRAVLGGAG---TRKRAAPAHG-GHRPPRLSR
MMAR_1238|M.marinum_M ALWELIWAGRVCGDTFAPVRALLGGGGP-GSRKRSAPAHR-GHRPPRLSR
MAV_4267|M.avium_104 ALWELVWAGWITGDTFAPVRALLGGGG---TRRRSAPAHR-AQRPPRLSR
MAB_3651|M.abscessus_ATCC_1997 ALWDLVWAGQVTGDTFAPVRALLGTST------TSRTAHR-NRRAPRLRA
MLBr_01333|M.leprae_Br4923 -----AWAGLRPAELAAVVSAVLYETRG---DDGPGGPVDAEAPTPRLRQ
MUL_2324|M.ulcerans_Agy99 -----AWAGLKPPELAAVVSCVLYETRG---SDGGGGRPGVEAPTPRLRQ
*** : * * .:* .***
Mflv_4810|M.gilvum_PYR-GCK YSLSTSSLSAHRDSDPTVAGRWSALPTAEVDTTVRAHYQADQLLARHGVL
Mvan_1632|M.vanbaalenii_PYR-1 YSLSTSSLSAHRDSDPTVAGRWSALPVAEVDTTVRAHYQADQLLARHGVL
MSMEG_1757|M.smegmatis_MC2_155 YSVAHAQT---RGTDPTVSGRWSALPAAEPDSTVRAHFQAELLLGRHGVL
TH_1222|M.thermoresistible__bu YSVVAAQT---RAADPTVAGRWSALPAPETDATVRAHFQAELLLHRYGVL
Mb3324|M.bovis_AF2122/97 YRLTHAQA---RNADPTVAGRWSALPLPEPDSTLRAHYQAELLLNRHGVL
Rv3296|M.tuberculosis_H37Rv YRLTHAQA---RNADPTVAGRWSALPLPEPDSTLRAHYQAELLLNRHGVL
MMAR_1238|M.marinum_M YSVAHAQP---RSVDPTVAGRWSLLPPPEPDSTVRAHYQAELLLNRHGVL
MAV_4267|M.avium_104 YSVAHPQA---RPADTTVAGRWSVLPPPEPDSTVRAHFQAELLLGRHGVL
MAB_3651|M.abscessus_ATCC_1997 YTPITTAA----PVDPAVAGRWSMLPERLTGGTERSHIQAELLLGRYGVV
MLBr_01333|M.leprae_Br4923 ALQHTSRLS--ATLRADEQRHRIALSREPDDGFVGVIYCWARTGDLAAVL
MUL_2324|M.ulcerans_Agy99 ALIQTSRLS--VALRADEQAHRIGQSREPDDGFVNVVYRWARTGDLSAAL
. . : . . ..:
Mflv_4810|M.gilvum_PYR-GCK TKGAVASENFRGNIPGGFASMYKVLTTMEDAGRCQRGYFVESLGGAQFAT
Mvan_1632|M.vanbaalenii_PYR-1 TKGAVAGEN----IPGGFASMYKVLTTMEEAGRCQRGYFVESLGGAQFAT
MSMEG_1757|M.smegmatis_MC2_155 TKGAVGAEG----VPGGFATLYKVLSTFEDAGRCQRGYFVESLGGAQFAV
TH_1222|M.thermoresistible__bu TKGSVVAEA----VPGGFGTLYKVLTAFEEAGRCQRGYFVESLGGAQFAV
Mb3324|M.bovis_AF2122/97 TKDAVAAEG----VAGGFATLYKVLSAFEDAGRCQRGYFIESLGGAQFAV
Rv3296|M.tuberculosis_H37Rv TKDAVAAEG----VAGGFATLYKVLSAFEDAGRCQRGYFIESLGGAQFAV
MMAR_1238|M.marinum_M TKGAVASEG----VPGGFATLYKVLSAFEDAGRCQRGYFVESLGGAQFAV
MAV_4267|M.avium_104 TRGAVAAEG----VAGGFATLYKVLSTFEDAGRCQRGYFIESLGGAQFAV
MAB_3651|M.abscessus_ATCC_1997 TKGSVVAES----VAGGFAWLYKVLSTFEDNGRCRRGYFVESLGGAQFAS
MLBr_01333|M.leprae_Br4923 AAADASGNG-------------APLSAGDFVRWCR-------------QV
MUL_2324|M.ulcerans_Agy99 AAADIEGPG-------------SPLSAGDFVRWCR-------------QV
: . *:: : *:
Mflv_4810|M.gilvum_PYR-GCK ASTVDRLRSHADS----IDDQQQKLRAVTLAATDPANPYGAALPWPSRGT
Mvan_1632|M.vanbaalenii_PYR-1 ASTVDRLRSHADS----IDDQQHTLRAVALAATDPANPYGAALPWPSRGG
MSMEG_1757|M.smegmatis_MC2_155 ASTVDRLRSYLDN----VDPERPEYHAVVLAATDPANPYGAALGWPTD--
TH_1222|M.thermoresistible__bu ASTVDRLRSYLDS----VDPQRPGYHAVVLAAADPANPYGAALPWPAGGA
Mb3324|M.bovis_AF2122/97 ASTVDRLRSYLDG----VDPEQPDYHAVVLAAADPANPYGAALPWPASSA
Rv3296|M.tuberculosis_H37Rv ASTVDRLRSYLDG----VDPEQPDYHAVVLAAADPANPYGAALPWPASSA
MMAR_1238|M.marinum_M AATVDRLRSYLDDPSAFTDSRRPQYQAVLLAAADPANPYGAALPWPTSDD
MAV_4267|M.avium_104 ASTVDRLRGFADG----VDPQRPEYRAIVLAAADPANPYGAALPWPASSA
MAB_3651|M.abscessus_ATCC_1997 PATVDRLREYLDP----VDDARKPYRATVLAATDPANPYGAALVWPRATS
MLBr_01333|M.leprae_Br4923 LDLLDQLRNAAPE---------PDLRATAKRAINDVRRG-----------
MUL_2324|M.ulcerans_Agy99 LDLLDQVRNAAPD---------PEVRAAAKRAINDIRRG-----------
:*::* :* * : .
Mflv_4810|M.gilvum_PYR-GCK DG-DTAHRPGRKAGALVVLIDGELTWFVERGGRSLLSFTD--DAETANAA
Mvan_1632|M.vanbaalenii_PYR-1 E--DSAHRPGRKAGALVVLVDGALAWFVERGGRSLLSFTA--DAETCHAA
MSMEG_1757|M.smegmatis_MC2_155 ---SEAHRPGRKAGALVALVDGRLVWFLERGGRSLLSFG--ADADAQRAA
TH_1222|M.thermoresistible__bu GDPDVGHRPGRKAGALVVLVDGALRWFIERGGRSLLTFGDHADAEAHAAA
Mb3324|M.bovis_AF2122/97 DGT---ARPGRKAGALVVLVDGELAWFLERGGRSLLTFTD--DPEANHAA
Rv3296|M.tuberculosis_H37Rv DGT---ARPGRKAGALVVLVDGELAWFLERGGRSLLTFTD--DPEANHAA
MMAR_1238|M.marinum_M DGSNVGARPGRKAGALVVLVDGALAWFLERGGRTLLTFTD--DPEANAAA
MAV_4267|M.avium_104 DGA----RPGRKAGALVVLVDGELAWFLERGGRSLLTFTD--DPAAQHAA
MAB_3651|M.abscessus_ATCC_1997 ES---GHRPGRKAGALAVLVDGDLALYIERGGKSLLSFVI--DPTVLHAA
MLBr_01333|M.leprae_Br4923 ----------------VVAVDAG---------------------------
MUL_2324|M.ulcerans_Agy99 ----------------VVAVDAG---------------------------
.. :*.
Mflv_4810|M.gilvum_PYR-GCK AAALAELVTRHRVPALLVERIDGVPVLESR-----ESVMVEALILAGFSR
Mvan_1632|M.vanbaalenii_PYR-1 AASLAELVSRQRVPGLLVERIDGAPVLEAR-----DSAVAEALVQAGFAR
MSMEG_1757|M.smegmatis_MC2_155 AGALTDLVSAGRIPSLLVERINGVAVLDPDVD-AERAVVQDALLGAGLSR
TH_1222|M.thermoresistible__bu AAALAGLVTAGRVPSLLVERINGVPVLEPGAD-AARQAVVDALTGAGFSR
Mb3324|M.bovis_AF2122/97 AIGLADLVTAGRVASILVERADGMPVLQPG---GRASAALTALLAAGFVR
Rv3296|M.tuberculosis_H37Rv AIGLADLVTAGRVASILVERADGMPVLQPG---GRASAALTALLAAGFVR
MMAR_1238|M.marinum_M AIALADLVATRRVGSLLVERINGVPVLQAGA--GQASLAVTALADAGFLR
MAV_4267|M.avium_104 AAALAGLVSARRVAAILVERIDGVPALAPRGDGAAGNDALTALADAGFAR
MAB_3651|M.abscessus_ATCC_1997 ALGTMELVRDGGLDGLVIERIDGRSVFDIG-----DSAVVAALMEAGFAR
MLBr_01333|M.leprae_Br4923 --------------------------------------------------
MUL_2324|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK TPRGLRLR-
Mvan_1632|M.vanbaalenii_PYR-1 TPRGLRLR-
MSMEG_1757|M.smegmatis_MC2_155 TPRGLRLR-
TH_1222|M.thermoresistible__bu TPRGLRLR-
Mb3324|M.bovis_AF2122/97 TPRGLRRR-
Rv3296|M.tuberculosis_H37Rv TPRGLRRR-
MMAR_1238|M.marinum_M TPRGLRLR-
MAV_4267|M.avium_104 TPRGMRLR-
MAB_3651|M.abscessus_ATCC_1997 TPRGLRIRR
MLBr_01333|M.leprae_Br4923 ---------
MUL_2324|M.ulcerans_Agy99 ---------