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STARPEPLGPEPLGRFSAITREWFTNTFAAPTPAQASAWAAIAAGDNTLVIAPTGSGKTLAAFLWALDSL ARCPDRTAGTRVLYVSPLKALAVDVERNLRTPLAGLTRLAERRGLPPPQISVGVRSGDTPPAVRRQLITR PPDVLITTPESLFLMLTSAARETLAGVQTVIVDEIHAIAATKRGAHLALSLERLDQLAPDRRAGPPAQRI GLSATVRPPEELARFLSGSAPTTIVAPHSAKTFDLTVQVPVADMANLANNTIWPDVESRLVDLIESHNST IVFANSRRLAERLTARLNEIHAERSGMTLPSEANTQVAGGAPAQIMASGQTFGAATLLARAHHGSVSKEQ RAQVEEDLKRGALKAVVATSSLELGIDMGAVDLVIQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHR TDLLGCAISVQRMRTGQIETMRVPANPLDILAQHTVAAAALEPLDADQWFDTVRRSASFATLPRSVFEAT LDLLSGKYPSTEFAELRPRLVYDRGTGTLTARPGAQRLAVTSGGAIPDRGLFTVYLASEAEKPSRVGELD EEMVYESRPGDVISLGATSWRITEITHDRVLVIPAPGEPARLPFWRGDDVGRPAELGAALGALTGELARL DRAEFDKRCAGLGFDDFATDNLWGLLDDQKTATRVVPTDTTLLVERFRDELGDWRVILHSPYGLRVHGPL ALAVGRRLRDRYGLDEKPTASDDGIVVRLPDTISDTGTETPPGAELFLFDADEIDAIVTAEVGASALFAS RFRESAARALLLPRRHPGRRSPLWHQRQRAAQLLDVARKYPDFPMVLETVRECLQDVYDVPTLTTLMTDI AQRRVRVAETETTKPSPFAASLLFGYVGAFMYEGDVPLAERRAAALSLDSTLLAELLGRVELRELLDPEV IAATGRQLQHLCADRAARDAEGVADLLRLLGPLTEDEVAARSDTTGGTDIGGWLEGLRAARRALEVSYAG RSWWVAVEDIGRLRDGVGAAVPVGLPAAFTEAVADPLAELLGRYARTHPPFTTAEAAGRFGLGLRVTADV LGRLASDGRLVRGDFVATGVFGGAGSEQWCDAEVLRILRRRSLAALRAQVEPVSTAAYGRFLPEWHQVGG ADSSHGGIDRLASVIDQLAGVRIPASALEPLVLAPRVRDYSPAMLDELLATGEVTWAGAGSISGSDGWVT LHLADSAPLTLAAPAEIEFGEAHRAILDTLAGGGAYFFRQLIGDIPDEAAIKAALWELIWAGRVCGDTFA PVRALLGGGGPGSRKRSAPAHRGHRPPRLSRYSVAHAQPRSVDPTVAGRWSLLPPPEPDSTVRAHYQAEL LLNRHGVLTKGAVASEGVPGGFATLYKVLSAFEDAGRCQRGYFVESLGGAQFAVAATVDRLRSYLDDPSA FTDSRRPQYQAVLLAAADPANPYGAALPWPTSDDDGSNVGARPGRKAGALVVLVDGALAWFLERGGRTLL TFTDDPEANAAAAIALADLVATRRVGSLLVERINGVPVLQAGAGQASLAVTALADAGFLRTPRGLRLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1238 | lhr | - | 100% (1539) | ATP-dependent helicase Lhr |
| M. marinum M | MMAR_5141 | - | 3e-18 | 27.98% (461) | DEAD/DEAH box helicase |
| M. marinum M | MMAR_1346 | rhlE | 3e-10 | 24.88% (410) | ATP-dependent RNA helicase RhlE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3324 | lhr | 0.0 | 83.68% (1532) | ATP-dependent helicase |
| M. gilvum PYR-GCK | Mflv_4810 | - | 0.0 | 74.58% (1542) | DEAD/DEAH box helicase domain-containing protein |
| M. tuberculosis H37Rv | Rv3296 | lhr | 0.0 | 83.81% (1532) | ATP-dependent helicase |
| M. leprae Br4923 | MLBr_00811 | rhlE | 1e-09 | 24.87% (398) | putative ATP-dependent RNA helicase |
| M. abscessus ATCC 19977 | MAB_3651 | - | 0.0 | 67.91% (1555) | ATP-dependent helicase Lhr |
| M. avium 104 | MAV_4267 | - | 0.0 | 82.39% (1556) | DEAD/DEAH box helicase |
| M. smegmatis MC2 155 | MSMEG_1757 | - | 0.0 | 76.04% (1536) | DEAD/DEAH box helicase |
| M. thermoresistible (build 8) | TH_1222 | - | 0.0 | 75.50% (906) | PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED |
| M. ulcerans Agy99 | MUL_2533 | rhlE | 6e-11 | 25.12% (410) | ATP-dependent RNA helicase RhlE |
| M. vanbaalenii PYR-1 | Mvan_1632 | - | 0.0 | 75.36% (1538) | DEAD/DEAH box helicase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4810|M.gilvum_PYR-GCK ---MPAKT-----DPLSRFSTLTREWFAGTFVEPTPAQAQAWNAISAGEN
Mvan_1632|M.vanbaalenii_PYR-1 MEHMPTET-----DPLARFSALTREWFTGTFVKPTPAQAQAWNAIADGDN
Mb3324|M.bovis_AF2122/97 --MRFAQP-----SALSRFSALTRDWFTSTFAAPTAAQASAWAAIADGDN
Rv3296|M.tuberculosis_H37Rv --MRFAQP-----SALSRFSALTRDWFTSTFAAPTAAQASAWAAIADGDN
MMAR_1238|M.marinum_M --MSTARPEPLGPEPLGRFSAITREWFTNTFAAPTPAQASAWAAIAAGDN
MAV_4267|M.avium_104 -MSTRAEPRP--SDPLGRFSAITREWFTSTFAAPTTAQAQAWSAIADGHN
MSMEG_1757|M.smegmatis_MC2_155 --MTTNGA-----DPLGRFSALTREWFTTAFAAPTPAQADAWSAISEGNN
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 ---MSSEP-----GPLARFSAPTREWFTESFPTPTRAQSGAWQSIANGDN
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK TLVIAPTGSGKTLAAFLWAIDGLAR--------EPRAERGTRVLYVSPLK
Mvan_1632|M.vanbaalenii_PYR-1 TLVIAPTGSGKTLAAFLWAIDGLAR--------EPAAQRGTRVLYVSPLK
Mb3324|M.bovis_AF2122/97 TLVIAPTGSGKTLAAFLWALDSLAGSE-----PMSERPAATRVLYVSPLK
Rv3296|M.tuberculosis_H37Rv TLVIAPTGSGKTLAAFLWALDSLAGSE-----PMSERPAATRVLYVSPLK
MMAR_1238|M.marinum_M TLVIAPTGSGKTLAAFLWALDSLAR--------CPDRTAGTRVLYVSPLK
MAV_4267|M.avium_104 TLVIAPTGSGKTLAAFLWALDSLAG--------QAERAPGTRVLYVSPLK
MSMEG_1757|M.smegmatis_MC2_155 TLVIAPTGSGKTLAAFLWAIDRLADP-------AREPSQGTQVLYVSPLK
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 TLVIAPTGSGKTLAAFLWAIDTLVQEKEAEAAAESRRLRGSRVLYVSPLK
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK ALAVDVERNLRTPLTGISRIAERNGEEPPAISVGVRSGDTTPSKRRELIT
Mvan_1632|M.vanbaalenii_PYR-1 ALAVDVERNLRTPLTGISRIAERTGQQPPAISVGVRSGDTTPSKRRELIT
Mb3324|M.bovis_AF2122/97 ALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVGVRSGDTPPALRRQLVS
Rv3296|M.tuberculosis_H37Rv ALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVGVRSGDTPPALRRQLVS
MMAR_1238|M.marinum_M ALAVDVERNLRTPLAGLTRLAERRGLPPPQISVGVRSGDTPPAVRRQLIT
MAV_4267|M.avium_104 ALAVDVERNLRTPLAGLTRIAERAGLPAPDISVGVRSGDTPPAVRRQLIN
MSMEG_1757|M.smegmatis_MC2_155 ALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDTPPNQRRAMIA
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 ALAVDVERNLRAPLAGIARTAARMGLPEPAITIGVRSGDTPAQRRRTLIS
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK KPPDILITTPESLFLMLTSAARESLSDIETVIVDEVHAVAATKRGAHLAV
Mvan_1632|M.vanbaalenii_PYR-1 KPPDILITTPESLFLMLTSAARETLSQVQTVIVDEVHAVAGTKRGAHLAV
Mb3324|M.bovis_AF2122/97 QPPDVLITTPESLFLMLTSAARQTLTGVQTVIIDEIHAIAATKRGAHLAL
Rv3296|M.tuberculosis_H37Rv QPPDVLITTPESLFLMLTSAARQTLTGVQTVIIDEIHAIAATKRGAHLAL
MMAR_1238|M.marinum_M RPPDVLITTPESLFLMLTSAARETLAGVQTVIVDEIHAIAATKRGAHLAL
MAV_4267|M.avium_104 RPPDVLITTPESLFLMLTSAARETLAGVQTVIVDEIHAIAGGKRGAHLAL
MSMEG_1757|M.smegmatis_MC2_155 NPPDVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLAL
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 SPPDILITTPESLYLMLTSAARETLDTVRTVIVDEVHAVAGTKRGAHLAL
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK SLERLDAMLPKPAQ-----RIGLSATVRPPEEVARFLSGASP---TTIVA
Mvan_1632|M.vanbaalenii_PYR-1 SLERLDAMLPKPAQ-----RIGLSATVRPPEEVARFLSGAAP---TTIVA
Mb3324|M.bovis_AF2122/97 SLERLDDLSSRRRA----QRIGLSATVRPPEELARFLSGQSP---TTIVA
Rv3296|M.tuberculosis_H37Rv SLERLDDLSSRRRA----QRIGLSATVRPPEELARFLSGQSP---TTIVA
MMAR_1238|M.marinum_M SLERLDQLAPDRRAGPPAQRIGLSATVRPPEELARFLSGSAP---TTIVA
MAV_4267|M.avium_104 SLERLDALREGRPA----QRIGLSATVRPPDELARFLSGAAPGTRTTVVA
MSMEG_1757|M.smegmatis_MC2_155 SLERLDQLLDTPAQ-----RIGLSATVRPPEEVARFLSGQAP---TTIVC
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 SLERLDERLSQPAQ-----RIGLSATVKPAAEVARFLSGRAP---ATVVA
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK PPAAKTFDLTVQVPVPDMAAPN---------------TGSIWPDVEERIV
Mvan_1632|M.vanbaalenii_PYR-1 PPAAKTFDLTVQVPVPDMANLE---------------NNSIWPEVEQRIV
Mb3324|M.bovis_AF2122/97 PPAAKTVELSVQVPVPDMANLT---------------DNTIWPDVEARLV
Rv3296|M.tuberculosis_H37Rv PPAAKTVELSVQVPVPDMANLT---------------DNTIWPDVEARLV
MMAR_1238|M.marinum_M PHSAKTFDLTVQVPVADMANLA---------------NNTIWPDVESRLV
MAV_4267|M.avium_104 PPSAKTVELSVQVPVPDMANLA---------------NNTIWPDVENRLV
MSMEG_1757|M.smegmatis_MC2_155 PPAAKTFDLSVQVPVPDMANLD---------------NNSIWPDVEERIV
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 PASPKTFDLSVVVPVSDMSAPESFPEPEASPDSTRGGATSLWPHVEQRIV
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK DLIEAHNSSIVFTNSRRLAERLTARINEIHAERTGIELG-AHNPGVAGGA
Mvan_1632|M.vanbaalenii_PYR-1 DLVEAHNSSIVFANSRRLAERLTARLNEIHAERLGVELG-GANPGVAGGA
Mb3324|M.bovis_AF2122/97 DLIESHNSTIVFANSRRLAERLTARLNEIHAARCGIELAPDTNQQVAGGA
Rv3296|M.tuberculosis_H37Rv DLIESHNSTIVFANSRRLAERLTARLNEIHAARCGIELAPDTNQQVAGGA
MMAR_1238|M.marinum_M DLIESHNSTIVFANSRRLAERLTARLNEIHAERSGMTLPSEANTQVAGGA
MAV_4267|M.avium_104 DLIEAHGSTIVFANSRRLAERLTARLNEIHAERSGVELSATANPKVAGGA
MSMEG_1757|M.smegmatis_MC2_155 DLVEAHNSSIVFANSRRLAERLTSRLNEIHAERSGIELPAGPNPEVGGGA
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 DLIEAHRSSIVFANSRRLAERLTARFNEIHAERLGLDLTPMPNPDVPGGP
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK PAHLMGSGQTYGAEPVLARAHHGSVSKEARADVEDALKSGRLKAVVATSS
Mvan_1632|M.vanbaalenii_PYR-1 PAHLMGSGQTYGAEPLLARAHHGSVSKEARADVEEALKSGRLKAVVATSS
Mb3324|M.bovis_AF2122/97 PAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKRGQLKAVVATSS
Rv3296|M.tuberculosis_H37Rv PAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKRGQLKAVVATSS
MMAR_1238|M.marinum_M PAQIMASGQTFGAATLLARAHHGSVSKEQRAQVEEDLKRGALKAVVATSS
MAV_4267|M.avium_104 PAHIMASGQTYGVEPILARAHHGSVSKEQRALVEEDLKRGLLKAVVATSS
MSMEG_1757|M.smegmatis_MC2_155 PAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLRAVVATSS
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 PAHIMGSGQTYGAAPLLARAHHGSVSKEQRADIEDDLKTGRLKCVVATSS
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK LELGIDMGAVDLVIQVETPPSVASGLQRVGRAGHQVGEISQGVLFPKHRT
Mvan_1632|M.vanbaalenii_PYR-1 LELGIDMGAVDLVIQVETPPSVASGLQRIGRAGHQVGEISQGVLFPKHRT
Mb3324|M.bovis_AF2122/97 LELGIDMGAVDLVIQVQAPPSVASGLQRIGRAGHQVGEISRGVLFPKHRT
Rv3296|M.tuberculosis_H37Rv LELGIDMGAVDLVIQVQAPPSVASGLQRIGRAGHQVGEISRGVLFPKHRT
MMAR_1238|M.marinum_M LELGIDMGAVDLVIQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHRT
MAV_4267|M.avium_104 LELGIDMGAVDLVIQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHRT
MSMEG_1757|M.smegmatis_MC2_155 LELGIDMGAVDLVIQVEAPPSVASGLQRVGRAGHQVGEISQGVLFPKHRT
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 LELGIDMGAVDLVVQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHRT
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK DLIGCAVSVQRMLAGQIETMRVPANPLDVLAQHTVAASALEPINADAWFD
Mvan_1632|M.vanbaalenii_PYR-1 DLIGCAVSVQRMLAGQIETMRVPANPLDVLAQHTVAACALEPINAEAWFD
Mb3324|M.bovis_AF2122/97 DLLGCAVSVQRMLAGEIETMRVPANPLDILAQHTVAAAALEPLDADAWFD
Rv3296|M.tuberculosis_H37Rv DLLGCAVSVQRMLAGEIETMRVPANPLDILAQHTVAAAALEPLDADAWFD
MMAR_1238|M.marinum_M DLLGCAISVQRMRTGQIETMRVPANPLDILAQHTVAAAALEPLDADQWFD
MAV_4267|M.avium_104 DLIGCAVTVQRMLAGQIETMRVPANPLDILAQQTVAAAALEPLDADRWFD
MSMEG_1757|M.smegmatis_MC2_155 DLIGCAVTVQRMQTGDIETLRVPANPLDVLAQHTVAVAALEPVDADAWFD
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 DLLGCAVTVRRMLDGDIETLQVPANPLDILAQHTVAACALESMDVEKWFD
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK TVRRSAPFATLPRSAFEATLDLLSGKYPSTEFAELRPRIVYDRDNGMLTS
Mvan_1632|M.vanbaalenii_PYR-1 TVRRSAPFATLPRSAFEATLDLLSGKYPSTEFAELRPRIVYDRDTGTLTS
Mb3324|M.bovis_AF2122/97 TVRRAAPFATLPRSLFEATLDLLSGKYPSTEFAELRPRLVYDRDTGTLTA
Rv3296|M.tuberculosis_H37Rv TVRRAAPFATLPRSLFEATLDLLSGKYPSTEFAELRPRLVYDRDTGTLTA
MMAR_1238|M.marinum_M TVRRSASFATLPRSVFEATLDLLSGKYPSTEFAELRPRLVYDRGTGTLTA
MAV_4267|M.avium_104 TVRRAAPFATLPRSIYEATLDLLSGKYPSTEFAELRPRLVYDRNTGTLTA
MSMEG_1757|M.smegmatis_MC2_155 AVRRSAPFATLPRSAFEATLDLLSGKYPSTEFAELRPRLVYDRDTGTLTA
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 VVRRSAPFTSLPRSAFDAVLDLLSGKYPSTDFAELRPRVVYDRDEGTLTG
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK RPGAQRLAVTSGGAIPDRGMFTVFLASSAESEKPSRVGELDEEMVYESRP
Mvan_1632|M.vanbaalenii_PYR-1 RPGAQRLAVTSGGAIPDRGLFTVFLASSADSEKPSRVGELDEEMVYESRP
Mb3324|M.bovis_AF2122/97 RPGAQRLAVTSGGAIPDRGLFAVYLATER----PSRVGELDEEMVYESRP
Rv3296|M.tuberculosis_H37Rv RPGAQRLAVTSGGAIPDRGLFAVYLATER----PSRVGELDEEMVYESRP
MMAR_1238|M.marinum_M RPGAQRLAVTSGGAIPDRGLFTVYLASEAE--KPSRVGELDEEMVYESRP
MAV_4267|M.avium_104 RPGAQRLAVTSGGAIPDRGLFTVYLASEAE--KPSRVGELEEEMVYESRP
MSMEG_1757|M.smegmatis_MC2_155 RPGAQRLAVTSGGAIPDRGMFTVYLASETE--KPSRVGELDEEMVYESRP
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 RPGAQRLAVTSGGAIPDRGLFTVYMYAGAEGEKPSRVGELDEEMVYESRP
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK GDVISLGATSWRITEITHDRVLVIPAPGEPARLPFWRGDGVGRPVELGAA
Mvan_1632|M.vanbaalenii_PYR-1 GDVISLGATSWRITEITHDRVLVIPAPGEPARLPFWRGDGVGRPAELGAA
Mb3324|M.bovis_AF2122/97 GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDDAGRPAELGAA
Rv3296|M.tuberculosis_H37Rv GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDDAGRPAELGAA
MMAR_1238|M.marinum_M GDVISLGATSWRITEITHDRVLVIPAPGEPARLPFWRGDDVGRPAELGAA
MAV_4267|M.avium_104 GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDGVGRPAELGAA
MSMEG_1757|M.smegmatis_MC2_155 GDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDSVGRPAELGAA
TH_1222|M.thermoresistible__bu --------------------------------------------------
MAB_3651|M.abscessus_ATCC_1997 GDVISLGATSWRITEITHERVVVVPAFGQPGRLPFWRGDSVGRPAELGIA
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK IGAFNGELARLDRPAFESRCRDVGFDDFATDNLWQLISEQREATSSVPSD
Mvan_1632|M.vanbaalenii_PYR-1 IGAFTGELARLDRDAFESRCQEVGFDAFATDNLWQLISEQRDATSAVPSD
Mb3324|M.bovis_AF2122/97 LGALTGELAALDRTAFGTRCAGLGFDDYATDNLWRLLDDQRTATAVVPTD
Rv3296|M.tuberculosis_H37Rv LGALTGELAALDRTAFGTRCAGLGFDDYATDNLWRLLDDQRTATAVVPTD
MMAR_1238|M.marinum_M LGALTGELARLDRAEFDKRCAGLGFDDFATDNLWGLLDDQKTATRVVPTD
MAV_4267|M.avium_104 LGAFTGELAGLSREEFDSRCAALGFDAYAVDNLYGLFDEQRTAAGVVPTD
MSMEG_1757|M.smegmatis_MC2_155 VGAFTGELASLDRKAFDKRCQKMGFAGYATDNLHQLLREQREATGVVPSD
TH_1222|M.thermoresistible__bu ----------------------MGFDEFATTNLWQLLDEQRQSTGVVPSD
MAB_3651|M.abscessus_ATCC_1997 LGQLTGELASARDAEFDKRCAAMGFDDFATGNLRTLLTDQLRSTGAVPTD
MLBr_00811|M.leprae_Br4923 -------------------------MNRDSKTPTQNRFSHRKAFHPHMTA
MUL_2533|M.ulcerans_Agy99 --------------------------------------------MTALKS
.
Mflv_4810|M.gilvum_PYR-GCK TTLVVERFRDELGDWRVILHSPYGLRVHGPLALAVGKRLYERFGIDEKPT
Mvan_1632|M.vanbaalenii_PYR-1 TTLVVERFRDELGDWRVILHSPYGLRVHGPLALAVGKRLYERYGIDEKPT
Mb3324|M.bovis_AF2122/97 STLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDEKPT
Rv3296|M.tuberculosis_H37Rv STLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDEKPT
MMAR_1238|M.marinum_M TTLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGLDEKPT
MAV_4267|M.avium_104 TTLLVERFRDELGDWRVILHSPYGLGVNGPLALAVGRRLRERYGIDEKPT
MSMEG_1757|M.smegmatis_MC2_155 TTFVVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRERYGIDEKPT
TH_1222|M.thermoresistible__bu TTLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLAERYGIDEKPT
MAB_3651|M.abscessus_ATCC_1997 TTLIVERFRDELGDWRIVLHCPYGLRVNGPLALAISDRLQQRYGVSESPT
MLBr_00811|M.leprae_Br4923 PTSTAEPAFAKLGVRDEIVRALAERGIQQPFAIQE---------------
MUL_2533|M.ulcerans_Agy99 TTETTPKTFAELGVRDEIVRALGERDIEGPFAIQE---------------
.* . :** :::. :. *:*:
Mflv_4810|M.gilvum_PYR-GCK ASDDGIIVRLPDTDD--------TAPGADIFVFDADEIEPLVTTEVSSSA
Mvan_1632|M.vanbaalenii_PYR-1 ASDDGIIVRLPDTDD--------TAPGADIFVFDADEIEPLVTAEVSSSA
Mb3324|M.bovis_AF2122/97 ASDNGIMVRLPDTVS----AGEDSPPGAELFVFDADEIDPIVTTEVAGSA
Rv3296|M.tuberculosis_H37Rv ASDNGIVVRLPDTVS----AGEDSPPGAELFVFDADEIDPIVTTEVAGSA
MMAR_1238|M.marinum_M ASDDGIVVRLPDTISD---TGTETPPGAELFLFDADEIDAIVTAEVGASA
MAV_4267|M.avium_104 ASDDGVVVRLPDTVSDFASDGGDTPPGAELFVFDADEIDPIVTAEVGGSA
MSMEG_1757|M.smegmatis_MC2_155 ASDDGIIVRLPDSGD--------TPPGADLFVFDADEIEPIVTAEVGGSA
TH_1222|M.thermoresistible__bu ASDDGIIVRLPDTGD--------TQPGAELFVFDADEIEPLVTAEVGGSA
MAB_3651|M.abscessus_ATCC_1997 ATDDGIVVRLPDTDD--------SPPGADLFVFDAAEIESIVTREVGGSA
MLBr_00811|M.leprae_Br4923 -------LTLP-------------------LALAGDDVIGQARTGMGKTF
MUL_2533|M.ulcerans_Agy99 -------LTLP-------------------LALAGDDLIGQARTGMGKTF
: ** : : . :: . :. :
Mflv_4810|M.gilvum_PYR-GCK LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVARNYPDFPIV
Mvan_1632|M.vanbaalenii_PYR-1 LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVAKGYPDFPIV
Mb3324|M.bovis_AF2122/97 LFASRFRESAARALLLPRRHPGRRSPLWQQRQRAARLLEVARKYPDFPIV
Rv3296|M.tuberculosis_H37Rv LFASRFRESAARALLLPRRHPGRRSPLWQQRQRAARLLEVARKYPDFPIV
MMAR_1238|M.marinum_M LFASRFRESAARALLLPRRHPGRRSPLWHQRQRAAQLLDVARKYPDFPMV
MAV_4267|M.avium_104 LFASRFRECAARALLLPRRHPGRRSPLWQQRQRAAQLLEVARKYPDFPVV
MSMEG_1757|M.smegmatis_MC2_155 LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDIARKYPDFPIV
TH_1222|M.thermoresistible__bu LFASRFRECAARALLLPRRHPGKRSPLWHQRQRAAQLLDVARKYPDFPIV
MAB_3651|M.abscessus_ATCC_1997 LFAARFRECAARALLLPRRTPGRRSPLWQQRQRAAQLLDVARKHSDFPMV
MLBr_00811|M.leprae_Br4923 AFG---------------------VPLLQRISVTTTARPLSG-APRGLVV
MUL_2533|M.ulcerans_Agy99 AFG---------------------VPLLQRVSSGTGVRPLTG-APRALVV
*. ** :: . : :: . :*
Mflv_4810|M.gilvum_PYR-GCK LEAVRECLQDVYDVPALTALMDRIAQRRVRILEVETPTPSPFAASLLFGY
Mvan_1632|M.vanbaalenii_PYR-1 LEAVRECLQDVYDVPTLTALMGRIAQRRVRLLEVETPTPSPFAASLLFGY
Mb3324|M.bovis_AF2122/97 LETVRECLQNVYDVPILVELMARIAQRRVRVAEAETAKPSPFAASLLFGY
Rv3296|M.tuberculosis_H37Rv LETVRECLQDVYDVPILVELMARIAQRRVRVAEAETAKPSPFAASLLFGY
MMAR_1238|M.marinum_M LETVRECLQDVYDVPTLTTLMTDIAQRRVRVAETETTKPSPFAASLLFGY
MAV_4267|M.avium_104 LETVRECLQDVYDVPALVALMAGIAQRRVRVLEVETQRPSPFAASLLFGY
MSMEG_1757|M.smegmatis_MC2_155 LEAVRECLQDVYDVPALIELMHKIAQRRLRIVEVETATPSPFAASLLFGY
TH_1222|M.thermoresistible__bu LETVRECLQDVYDVPTLTELMRGIAQRRLRLIEVETAAPSPFAASLLFGY
MAB_3651|M.abscessus_ATCC_1997 LEALRECLQDVYDISTLVRLMSGIEQRRIRIVEVQTDTPSPFAAAQLFSY
MLBr_00811|M.leprae_Br4923 VPTRELCLQVADDLATVAKYLTAD------------DDNRRFSVVSIYG-
MUL_2533|M.ulcerans_Agy99 VPTRELCLQVTEDLAVAAKYLTATT---------ETGDQRPLSVVSIYG-
: : . *** . *:. : ::. ::.
Mflv_4810|M.gilvum_PYR-GCK VGAFMYEGDSPLAERRAAALALDPTLLAELLGRVELRELLDPDVIATTTR
Mvan_1632|M.vanbaalenii_PYR-1 VGAFMYEGDSPLAERRAAALSLDPTLLAELLGRVELRELLDADVVTTTAR
Mb3324|M.bovis_AF2122/97 VGAFMYEGDTPLAERRAAALALDGTLLAELLGRVELRELLDPDVIAATSR
Rv3296|M.tuberculosis_H37Rv VGAFMYEGDTPLAERRAAALALDGTLLAELLGRVELRELLDPDVIAATSR
MMAR_1238|M.marinum_M VGAFMYEGDVPLAERRAAALSLDSTLLAELLGRVELRELLDPEVIAATGR
MAV_4267|M.avium_104 VGAFMYEGDSPLAERRAAALSLDSTLLAELLGRVELRELLDPEVVAATAR
MSMEG_1757|M.smegmatis_MC2_155 VGAFMYEGDSPLAERRAAALALDTVLLSELLGRVELRELLDPAVVASTSA
TH_1222|M.thermoresistible__bu VGAFIYEGDSPLAERRAAALSLDPTLLAELLGRVELRELLDPDVVATTGR
MAB_3651|M.abscessus_ATCC_1997 IGGFMYDEDRPLAERRAAALSLDTNLLAELMGRVELRELLDPAVIDATER
MLBr_00811|M.leprae_Br4923 ---------GRAYEPQIEALQTGADVVVSTPG--RLLDLCQQGHLQLSGL
MUL_2533|M.ulcerans_Agy99 ---------GRAYEPQIEALRAGADVVVGTPG--RLLDLSQQGHLQLGGL
* : ** . :: * .* :* : :
Mflv_4810|M.gilvum_PYR-GCK QLQHLTPERAARDAEGVADLLRLLGPLTVDEIAER---CVQPDIGGWLEG
Mvan_1632|M.vanbaalenii_PYR-1 QLQHLTPERLARDAEGVADLLRLLGPLTTEEIAAR---CVVSEVGGWLEG
Mb3324|M.bovis_AF2122/97 QLQHLAADRVARDAEGVADLLRLLGPLTEDEIAAR---AGAPEVSGWLDG
Rv3296|M.tuberculosis_H37Rv QLQHLAADRVARDAEGVADLLRLLGPLTEDEIAAR---AGAPEVSGWLDG
MMAR_1238|M.marinum_M QLQHLCADRAARDAEGVADLLRLLGPLTEDEVAARSDTTGGTDIGGWLEG
MAV_4267|M.avium_104 ALQHLAPERAARDAEAVADLLRLLGPLTEDEVVARAGGADAVEVRGWLEG
MSMEG_1757|M.smegmatis_MC2_155 QLQHLTPERAARDAEGVADLLRLLGPLTEADIAQR---CTADNIGAWLDG
TH_1222|M.thermoresistible__bu QLQHLTADRAVRDVEGVADLLRMLGPLTAEEIAAR---STSADVGGWLDE
MAB_3651|M.abscessus_ATCC_1997 QLQHLAEERKARDAEALADLFRLLGPLTAEEIAQR----CAGPGAAWLDE
MLBr_00811|M.leprae_Br4923 SVLVLDEADEMLDLGFFPDIERLLGQIPTDRQSML---------------
MUL_2533|M.ulcerans_Agy99 YVLVLDEADEMLDLGFLPDIERILRQIPADRQSML---------------
: * * ..*: *:* :.
Mflv_4810|M.gilvum_PYR-GCK LLTSKRVVTLSFAGQTWWAAIEDIGRLRDGVGVAVPVGVPIAFLEPIVDP
Mvan_1632|M.vanbaalenii_PYR-1 LLGAKRAVQVSFAGQSWWAAVEDIGRLRDGVGVAVPVGVPMAFLEQVVDP
Mb3324|M.bovis_AF2122/97 LRAAKRALVVSFAGRSWWVAVEDMGRLRDGVGAAVPVGLPASFTEAVADP
Rv3296|M.tuberculosis_H37Rv LRAAKRALVVSFAGRSWWVAVEDMGRLRDGVGAAVPVGLPASFTEAVADP
MMAR_1238|M.marinum_M LRAARRALEVSYAGRSWWVAVEDIGRLRDGVGAAVPVGLPAAFTEAVADP
MAV_4267|M.avium_104 LRAARRAVPVSFAGRSWWVAIEDIGRLRDGLGIAVPLGVPAAFTEEVADP
MSMEG_1757|M.smegmatis_MC2_155 LHAAKRALPVTYAGQTWWAAVEDIGLLRDGIGVPVPVGVPAAFTESASDP
TH_1222|M.thermoresistible__bu LAAARRALRVSYAGRQWWVAVEDIGLLRDAVGVAVPVGVPTTFTGAVADP
MAB_3651|M.abscessus_ATCC_1997 LVSARRVVGTSYGQRSWWAAVEDVARLRDALGVPVPPGVPAAFTDAATDP
MLBr_00811|M.leprae_Br4923 ------------------------------------------FSATMPDP
MUL_2533|M.ulcerans_Agy99 ------------------------------------------FSATMPDP
* **
Mflv_4810|M.gilvum_PYR-GCK LSELLSRYARTRGPFTTMEAATRFGLGVRVAADVLGRLTA----DGKLVR
Mvan_1632|M.vanbaalenii_PYR-1 LGELLSRYARTRGPFTTAEAAARFGLGLRVAADVLGRLAV----DGKLVR
Mb3324|M.bovis_AF2122/97 LGELLGRYARTHTPFTTAAAAARFGLGLRVTADVLGRLAS----DGRLVR
Rv3296|M.tuberculosis_H37Rv LGELLGRYARTHTPFTTAAAAARFGLGLRVTADVLGRLAS----DGRLVR
MMAR_1238|M.marinum_M LAELLGRYARTHPPFTTAEAAGRFGLGLRVTADVLGRLAS----DGRLVR
MAV_4267|M.avium_104 LGELLGRYARTHTPFSTAEAAARFGLGLRVTADVLGRLADPSTSQGRLVR
MSMEG_1757|M.smegmatis_MC2_155 LGDLIGRYARTRGPFTTEQTAARFGLGVRVASDVLSRMAV----DGRLIR
TH_1222|M.thermoresistible__bu LGELLGRYARTRGPFTTAQAAARFGLGLRVAGDVLHRMAA----DGRLVR
MAB_3651|M.abscessus_ATCC_1997 LAELLSRYARTHGPFTTGEAAQRFGLGVRVAADTLSAMAA----RGQLVR
MLBr_00811|M.leprae_Br4923 IITLARTFMDQP---IHIRAEAPHSLAVHDTTQQFVYRAH------ALDK
MUL_2533|M.ulcerans_Agy99 IITLARTFMIQP---THIRAEAPHSLAVHDTTEQFVYRAH------ALDK
: * : : ..*.:: : : : : * :
Mflv_4810|M.gilvum_PYR-GCK GEFTDLP-----TESGVEQWCDAEVLRILRRRSLAALRAQIEPVSTGAFG
Mvan_1632|M.vanbaalenii_PYR-1 GEFTDAP-----TDSG-GQWCDAEVLRILRRRSLAALRAQIEPVSTAAFG
Mb3324|M.bovis_AF2122/97 GEFVAA----AEGSAGGEQWCDAEVLRILRRRSLAALRAQAEPVSTAAYG
Rv3296|M.tuberculosis_H37Rv GEFVAA----AKGSAGGEQWCDAEVLRILRRRSLAALRAQAEPVSTAAYG
MMAR_1238|M.marinum_M GDFVATG---VFGGAGSEQWCDAEVLRILRRRSLAALRAQVEPVSTAAYG
MAV_4267|M.avium_104 GDFVAARPSEPGGVLGAEQWCDADVLRILRRRSLAALRAQVEPVSTAAYG
MSMEG_1757|M.smegmatis_MC2_155 GEFAAD------LSG--EQWCDAQVLKILRRRSLAALRAQVEPVSTDAYA
TH_1222|M.thermoresistible__bu GEFTTD------AVDTTEQWCDAEVLRILRRRSLAALRAQVEPVSTAAFG
MAB_3651|M.abscessus_ATCC_1997 GEFTSD-------ATDSEQWCDAEVLRILRRRSLAALRAQVEPVSTSAFA
MLBr_00811|M.leprae_Br4923 VELISR-------------------ILQARGRGATMIFTRTKRTAQKVTN
MUL_2533|M.ulcerans_Agy99 VELVTR-------------------VLQARERGATMIFTRTKRTAQKVAD
:: : * *. : : :: : .: .
Mflv_4810|M.gilvum_PYR-GCK RFLPAWQMVGADSAS------GVDGLASVIDQLAGVPVPASAVEPLILGQ
Mvan_1632|M.vanbaalenii_PYR-1 RFLPAWQMLGGDAVS------GVDGLAAVIDQLAGVPMPASAVEPLIFGQ
Mb3324|M.bovis_AF2122/97 RFLPAWQHVSAGNS-------GIDGLAAVIDQLAGVRIPASAIEPLVLAP
Rv3296|M.tuberculosis_H37Rv RFLPAWQHVSAGNS-------GIDGLAAVIDQLAGVRIPASAIEPLVLAP
MMAR_1238|M.marinum_M RFLPEWHQVGGADSS----HGGIDRLASVIDQLAGVRIPASALEPLVLAP
MAV_4267|M.avium_104 RFLPAWHRVGAAESSRAPGHSGLDGLMSVIEQLAGVRLPASALEPLVLAP
MSMEG_1757|M.smegmatis_MC2_155 RFLPSWQHVGSTNT------TGIDGLATVIEQLAGVPIPASAVESLVFPQ
TH_1222|M.thermoresistible__bu RFLPAWQQVGTAN-------SGIDGLAAVIEQLAGVPMPASAVESLILPQ
MAB_3651|M.abscessus_ATCC_1997 RFLPDWQYLDSNLR-------GIDGVATVIEQLAGVPIPASAWEPLILAR
MLBr_00811|M.leprae_Br4923 ELNERGFAVGAVHG---------------------------DLGQIAREN
MUL_2533|M.ulcerans_Agy99 ELNERGFAVGAVHG---------------------------DLGQVAREK
.: :. :
Mflv_4810|M.gilvum_PYR-GCK RVRDYQPGMLDELLASGEVLWSGAGSLSA----ADGWVSFHPADTAPLSL
Mvan_1632|M.vanbaalenii_PYR-1 RVRDYQPGMLDELLASGEVLWSGVGSLST----ADGWVAFHLAETAPLSL
Mb3324|M.bovis_AF2122/97 RIRDYSPAMLDELLASGDVTWSGAGSISG----SDGWIALHPADSAPMTL
Rv3296|M.tuberculosis_H37Rv RIRDYSPAMLDELLASGDVTWSGAGSISG----SDGWIALHPADSAPMTL
MMAR_1238|M.marinum_M RVRDYSPAMLDELLATGEVTWAGAGSISG----SDGWVTLHLADSAPLTL
MAV_4267|M.avium_104 RVRDYSPALLDELLATGEVTWSGAGSISG----SDGWIALHPSESAPLTL
MSMEG_1757|M.smegmatis_MC2_155 RVRDYQPAMLDELLASGEVMWSGAGQIGN----GDGWVAFHLADTAPLTL
TH_1222|M.thermoresistible__bu RVRDYQPAMLDELLASGEVIWSGAGAIGGGATGADGWIAFHLGDSAPLTL
MAB_3651|M.abscessus_ATCC_1997 RIRDYSPQMLDELLASGEAVWSGQGSISA----QDGWIALHPSGVAPATL
MLBr_00811|M.leprae_Br4923 ALEAFRTGNVDVLVATDVAARG----------------------------
MUL_2533|M.ulcerans_Agy99 ALKSFRRGSVNVLVATDVAARG----------------------------
:. : :: *:*:. . .
Mflv_4810|M.gilvum_PYR-GCK APPGDLDLTDVHHQILAALAGGGAYFFRQLSLD---GVSSESLKEALWQL
Mvan_1632|M.vanbaalenii_PYR-1 APYGDLGLTDIHHAVLAALAGGGAYFFRQLTVD---GVGTESLKEALWQL
Mb3324|M.bovis_AF2122/97 AEPAEIDFTDAHRAILASLGTGGAYFFRQLTHD---GLTEAELKAALWEL
Rv3296|M.tuberculosis_H37Rv AEPAEIDFTDAHRAILASLGTGGAYFFRQLTHD---GLTEAELKAALWEL
MMAR_1238|M.marinum_M AAPAEIEFGEAHRAILDTLAGGGAYFFRQLIGD---IPDEAAIKAALWEL
MAV_4267|M.avium_104 QGPADIELGEAHRAILDVLAGGGGYFFRQLATD---GVSDAELKAALWEL
MSMEG_1757|M.smegmatis_MC2_155 THGAEIEFTDTHRVILETLGHGGAYFFRQLTDGTVEGTAGQELKQALWEL
TH_1222|M.thermoresistible__bu AEPAEIEFTDVHRAILDTLGGGGGYFFRQLAGG--AGTDTTAVRTALWEL
MAB_3651|M.abscessus_ATCC_1997 AAAETVILDDAHRAILNCLTAGGGYFFRQFGSD--------ATRAALWDL
MLBr_00811|M.leprae_Br4923 -----IDIDDVTHVINYQCPEDEKMYVHRIGRTGRAGRTGVAVTLVDWDE
MUL_2533|M.ulcerans_Agy99 -----IDIDDVTHVINYQCPEDEKMYVHRIGRTGRAGRTGVAVTLVDWDE
: : : : : . :.::: . *:
Mflv_4810|M.gilvum_PYR-GCK IWAGYVGGDTFAPVRALLAGTKGPGSRRTAAPSHR-HRRPPRLSRYSLST
Mvan_1632|M.vanbaalenii_PYR-1 IWAGYVGGDTFAPVRALLAGARGSGPRKSATPSHR-HRRAPRLSRYSLST
Mb3324|M.bovis_AF2122/97 IWAGRVTGDTFAPVRAVLGGAG---TRKRAAPAHG-GHRPPRLSRYRLTH
Rv3296|M.tuberculosis_H37Rv IWAGRVTGDTFAPVRAVLGGAG---TRKRAAPAHG-GHRPPRLSRYRLTH
MMAR_1238|M.marinum_M IWAGRVCGDTFAPVRALLGGGGP-GSRKRSAPAHR-GHRPPRLSRYSVAH
MAV_4267|M.avium_104 VWAGWITGDTFAPVRALLGGGG---TRRRSAPAHR-AQRPPRLSRYSVAH
MSMEG_1757|M.smegmatis_MC2_155 IWAGWVTGDTFAPVRAVLSGP-----RRSGAPAHRQRQRPPRLSRYSVAH
TH_1222|M.thermoresistible__bu VWAGWVTGDTFAPVRAMLSGAGR-TGRRGGAPAHQQSRRPPRLSRYSVVA
MAB_3651|M.abscessus_ATCC_1997 VWAGQVTGDTFAPVRALLGTST------TSRTAHR-NRRAPRLRAYTPIT
MLBr_00811|M.leprae_Br4923 LHR-------WETIDKALGLGT-------PDPAETYSNSPHLYTELAIPA
MUL_2533|M.ulcerans_Agy99 LPR-------WTMIDKALGLGS-------PDPAETYSSSPHLYTELSIPT
: : : *. .:. .
Mflv_4810|M.gilvum_PYR-GCK SSLSAHRDSDPTVAGRWSALPTAEVDTTVRAHYQADQLLARHGVLTKGAV
Mvan_1632|M.vanbaalenii_PYR-1 SSLSAHRDSDPTVAGRWSALPVAEVDTTVRAHYQADQLLARHGVLTKGAV
Mb3324|M.bovis_AF2122/97 AQA---RNADPTVAGRWSALPLPEPDSTLRAHYQAELLLNRHGVLTKDAV
Rv3296|M.tuberculosis_H37Rv AQA---RNADPTVAGRWSALPLPEPDSTLRAHYQAELLLNRHGVLTKDAV
MMAR_1238|M.marinum_M AQP---RSVDPTVAGRWSLLPPPEPDSTVRAHYQAELLLNRHGVLTKGAV
MAV_4267|M.avium_104 PQA---RPADTTVAGRWSVLPPPEPDSTVRAHFQAELLLGRHGVLTRGAV
MSMEG_1757|M.smegmatis_MC2_155 AQT---RGTDPTVSGRWSALPAAEPDSTVRAHFQAELLLGRHGVLTKGAV
TH_1222|M.thermoresistible__bu AQT---RAADPTVAGRWSALPAPETDATVRAHFQAELLLHRYGVLTKGSV
MAB_3651|M.abscessus_ATCC_1997 TAA----PVDPAVAGRWSMLPERLTGGTERSHIQAELLLGRYGVVTKGSV
MLBr_00811|M.leprae_Br4923 EASG--TVGTPRKAQVKRRKTDRDGDKSGTSAQAAKAARTSNSVQRHRIR
MUL_2533|M.ulcerans_Agy99 DAAG--TVGPPSKSGSKPRTTEKQDDQQGEKSGRAR----SDAGRRRRTR
. : . . * . :
Mflv_4810|M.gilvum_PYR-GCK ASENFRGNIPGGFASMYKVLTTMEDAGRCQRGYFVESLGGAQFATASTVD
Mvan_1632|M.vanbaalenii_PYR-1 AGEN----IPGGFASMYKVLTTMEEAGRCQRGYFVESLGGAQFATASTVD
Mb3324|M.bovis_AF2122/97 AAEG----VAGGFATLYKVLSAFEDAGRCQRGYFIESLGGAQFAVASTVD
Rv3296|M.tuberculosis_H37Rv AAEG----VAGGFATLYKVLSAFEDAGRCQRGYFIESLGGAQFAVASTVD
MMAR_1238|M.marinum_M ASEG----VPGGFATLYKVLSAFEDAGRCQRGYFVESLGGAQFAVAATVD
MAV_4267|M.avium_104 AAEG----VAGGFATLYKVLSTFEDAGRCQRGYFIESLGGAQFAVASTVD
MSMEG_1757|M.smegmatis_MC2_155 GAEG----VPGGFATLYKVLSTFEDAGRCQRGYFVESLGGAQFAVASTVD
TH_1222|M.thermoresistible__bu VAEA----VPGGFGTLYKVLTAFEEAGRCQRGYFVESLGGAQFAVASTVD
MAB_3651|M.abscessus_ATCC_1997 VAES----VAGGFAWLYKVLSTFEDNGRCRRGYFVESLGGAQFASPATVD
MLBr_00811|M.leprae_Br4923 GGQP-----VTGHPTNNPSADSLATNGKVVAETLPNSSSGSPSTN---VR
MUL_2533|M.ulcerans_Agy99 GGKP-----VTGHPATTPVAS-----GETATETGSGFGASSPSGNAGATR
.: *. *. ..: .
Mflv_4810|M.gilvum_PYR-GCK RLRSHADS----IDDQQQKLRAVTLAATDPANPYGAALPWPSRGTDG-DT
Mvan_1632|M.vanbaalenii_PYR-1 RLRSHADS----IDDQQHTLRAVALAATDPANPYGAALPWPSRGGE--DS
Mb3324|M.bovis_AF2122/97 RLRSYLDG----VDPEQPDYHAVVLAAADPANPYGAALPWPASSADGT--
Rv3296|M.tuberculosis_H37Rv RLRSYLDG----VDPEQPDYHAVVLAAADPANPYGAALPWPASSADGT--
MMAR_1238|M.marinum_M RLRSYLDDPSAFTDSRRPQYQAVLLAAADPANPYGAALPWPTSDDDGSNV
MAV_4267|M.avium_104 RLRGFADG----VDPQRPEYRAIVLAAADPANPYGAALPWPASSADGA--
MSMEG_1757|M.smegmatis_MC2_155 RLRSYLDN----VDPERPEYHAVVLAATDPANPYGAALGWPTD-----SE
TH_1222|M.thermoresistible__bu RLRSYLDS----VDPQRPGYHAVVLAAADPANPYGAALPWPAGGAGDPDV
MAB_3651|M.abscessus_ATCC_1997 RLREYLDP----VDDARKPYRATVLAATDPANPYGAALVWPRATSES---
MLBr_00811|M.leprae_Br4923 RRRHRRKP----TEVAENGLDKNLAVQAN---------------------
MUL_2533|M.ulcerans_Agy99 RRRRRRKP----AGVQDN-----AAASAN---------------------
* * . . ::
Mflv_4810|M.gilvum_PYR-GCK AHRPGRKAGALVVLIDGELTWFVERGGRSLLSFTD--DAETANAAAAALA
Mvan_1632|M.vanbaalenii_PYR-1 AHRPGRKAGALVVLVDGALAWFVERGGRSLLSFTA--DAETCHAAAASLA
Mb3324|M.bovis_AF2122/97 -ARPGRKAGALVVLVDGELAWFLERGGRSLLTFTD--DPEANHAAAIGLA
Rv3296|M.tuberculosis_H37Rv -ARPGRKAGALVVLVDGELAWFLERGGRSLLTFTD--DPEANHAAAIGLA
MMAR_1238|M.marinum_M GARPGRKAGALVVLVDGALAWFLERGGRTLLTFTD--DPEANAAAAIALA
MAV_4267|M.avium_104 --RPGRKAGALVVLVDGELAWFLERGGRSLLTFTD--DPAAQHAAAAALA
MSMEG_1757|M.smegmatis_MC2_155 AHRPGRKAGALVALVDGRLVWFLERGGRSLLSFG--ADADAQRAAAGALT
TH_1222|M.thermoresistible__bu GHRPGRKAGALVVLVDGALRWFIERGGRSLLTFGDHADAEAHAAAAAALA
MAB_3651|M.abscessus_ATCC_1997 GHRPGRKAGALAVLVDGDLALYIERGGKSLLSFVI--DPTVLHAAALGTM
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK ELVTRHRVPALLVERIDGVPVLESR-----ESVMVEALILAGFSRTPRGL
Mvan_1632|M.vanbaalenii_PYR-1 ELVSRQRVPGLLVERIDGAPVLEAR-----DSAVAEALVQAGFARTPRGL
Mb3324|M.bovis_AF2122/97 DLVTAGRVASILVERADGMPVLQPG---GRASAALTALLAAGFVRTPRGL
Rv3296|M.tuberculosis_H37Rv DLVTAGRVASILVERADGMPVLQPG---GRASAALTALLAAGFVRTPRGL
MMAR_1238|M.marinum_M DLVATRRVGSLLVERINGVPVLQAGA--GQASLAVTALADAGFLRTPRGL
MAV_4267|M.avium_104 GLVSARRVAAILVERIDGVPALAPRGDGAAGNDALTALADAGFARTPRGM
MSMEG_1757|M.smegmatis_MC2_155 DLVSAGRIPSLLVERINGVAVLDPDVD-AERAVVQDALLGAGLSRTPRGL
TH_1222|M.thermoresistible__bu GLVTAGRVPSLLVERINGVPVLEPGAD-AARQAVVDALTGAGFSRTPRGL
MAB_3651|M.abscessus_ATCC_1997 ELVRDGGLDGLVIERIDGRSVFDIG-----DSAVVAALMEAGFARTPRGL
MLBr_00811|M.leprae_Br4923 --------------------------------------------------
MUL_2533|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4810|M.gilvum_PYR-GCK RLR-
Mvan_1632|M.vanbaalenii_PYR-1 RLR-
Mb3324|M.bovis_AF2122/97 RRR-
Rv3296|M.tuberculosis_H37Rv RRR-
MMAR_1238|M.marinum_M RLR-
MAV_4267|M.avium_104 RLR-
MSMEG_1757|M.smegmatis_MC2_155 RLR-
TH_1222|M.thermoresistible__bu RLR-
MAB_3651|M.abscessus_ATCC_1997 RIRR
MLBr_00811|M.leprae_Br4923 ----
MUL_2533|M.ulcerans_Agy99 ----